Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Kádár-Pauncz J et al. | Isolation and structure elucidation of new antibiotics related to angolamycin. | 1992 | J. Antibiot. | pmid:1399843 |
Arzey GG and Arzey KE | Successful treatment of mycoplasmosis in layer chickens with single dose therapy. | 1992 | Aust. Vet. J. | pmid:1379426 |
Huang SL et al. | Purification and properties of NADPH-dependent tylosin reductase from Streptomyces fradiae. | 1993 | J. Biol. Chem. | pmid:8360186 |
Binder S et al. | [The effectiveness of tilmicosin in respiratory diseases of swine]. | 1993 | Berl. Munch. Tierarztl. Wochenschr. | pmid:8431202 |
Cester CC et al. | Effect of stage of oestrous cycle on tylosin disposition in genital tract secretions of cows. | 1993 | Res. Vet. Sci. | pmid:8434145 |
Jordan FT et al. | A comparison of the efficacy of danofloxacin and tylosin in the control of Mycoplasma gallisepticum infection in broiler chicks. | 1993 | J. Vet. Pharmacol. Ther. | pmid:8386777 |
Meisel ML et al. | Tylosin inhibits the steroidogenesis in mouse Leydig cells "in vitro". | 1993 | Life Sci. | pmid:8390595 |
Kageyama S et al. | Synthesis of 3-deoxy-3,4-didehydro derivatives of 5-O-mycaminosyltylonolide, 5-O-(4-deoxymycaminosyl) tylonolide, and desmycosin. | 1993 | J. Antibiot. | pmid:8407589 |
Danielson ND et al. | Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. | 1993 | J Pharm Biomed Anal | pmid:8504183 |
Lee SH and Lee KJ | Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae. | 1993 | Appl. Environ. Microbiol. | pmid:8481008 |