Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

MeSH term MeSH ID Detail
Digital Dermatitis D058066 3 associated lipids
Bovine Respiratory Disease Complex D048090 2 associated lipids
Pneumonia of Calves, Enzootic D048089 2 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Pneumonia of Swine, Mycoplasmal D045729 2 associated lipids
Porcine Reproductive and Respiratory Syndrome D019318 4 associated lipids
Primate Diseases D018419 2 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Neisseriaceae Infections D016870 3 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Bacillaceae Infections D016863 1 associated lipids
Mycotoxicosis D015651 5 associated lipids
Weight Gain D015430 101 associated lipids
Vasculitis D014657 14 associated lipids
Treponemal Infections D014211 3 associated lipids
Tracheal Diseases D014133 3 associated lipids
Swine Diseases D013553 16 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Pasteurellosis, Pneumonic D012766 3 associated lipids
Pyoderma D011711 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

Download all related citations
Per page 10 20 50 100 | Total 931
Authors Title Published Journal PubMed Link
Frank GH et al. Effects of tilmicosin treatment on Pasteurella haemolytica organisms in nasal secretion specimens of calves with respiratory tract disease. 2000 Am. J. Vet. Res. pmid:10803647
Baggesen DL et al. Effects of the antimicrobial growth promoter tylosin on subclinical infection of pigs with Salmonella enterica serotype Typhimurium. 1999 Am. J. Vet. Res. pmid:10791930
Moore GM et al. Efficacy dose determination study of tilmicosin phosphate in feed for control of pneumonia caused by Actinobacillus pleuropneumoniae in swine. 1996 Am. J. Vet. Res. pmid:8633812
Shen J et al. Pharmacokinetics of tilmicosin after oral administration in swine. 2005 Am. J. Vet. Res. pmid:16008233
Wittum TE et al. Haptoglobin response to clinical respiratory tract disease in feedlot cattle. 1996 Am. J. Vet. Res. pmid:8723875
Brumbaugh GW et al. Effect of tilmicosin on chemotactic, phagocytic, and bactericidal activities of bovine and porcine alveolar macrophages. 2002 Am. J. Vet. Res. pmid:16206777
Mendoza J et al. Concentrations of tilmicosin in mammary gland secretions of dairy cows following subcutaneous administration of one or two doses of an experimental preparation of tilmicosin and its efficacy against intramammary infections caused by Staphylococcus aureus. 2016 Am. J. Vet. Res. pmid:27580103
McKay SG et al. Use of tilmicosin for treatment of pasteurellosis in rabbits. 1996 Am. J. Vet. Res. pmid:8836371
McOrist S et al. Oral administration of tylosin phosphate for treatment and prevention of proliferative enteropathy in pigs. 1997 Am. J. Vet. Res. pmid:9028475
Frank GH and Duff GC Effects of tilmicosin phosphate, administered prior to transport or at time of arrival, and feeding of chlortetracycline, after arrival in a feedlot, on Mannheimia haemolytica in nasal secretions of transported steers. 2000 Am. J. Vet. Res. pmid:11131584
Carter JN et al. Relationship of vitamin E supplementation and antimicrobial treatment with acute-phase protein responses in cattle affected by naturally acquired respiratory tract disease. 2002 Am. J. Vet. Res. pmid:12171163
Nouri M and Constable PD Effect of parenteral administration of erythromycin, tilmicosin, and tylosin on abomasal emptying rate in suckling calves. 2007 Am. J. Vet. Res. pmid:18052746
Jacobsen AM and Halling-Sørensen B Multi-component analysis of tetracyclines, sulfonamides and tylosin in swine manure by liquid chromatography-tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16485090
Yang S et al. Trace analysis and occurrence of anhydroerythromycin and tylosin in influent and effluent wastewater by liquid chromatography combined with electrospray tandem mass spectrometry. 2006 Anal Bioanal Chem pmid:16715282
Zheng Y et al. Molecularly imprinted solid-phase extraction for determination of tilmicosin in feed using high performance liquid chromatography. 2011 Anal. Chim. Acta pmid:21435486
Bohm DA et al. Preparation and characterisation of in-house reference material of tylosin in honey and results of a proficiency test. 2011 Anal. Chim. Acta pmid:21742117
Thompson TS et al. Degradation of incurred tylosin to desmycosin--implications for residue analysis of honey. 2007 Anal. Chim. Acta pmid:17386728
De Liguoro M et al. Determination of tylosin residues in pig tissues using high-performance liquid chromatography. 1998 Analyst pmid:9764508
Ammida NH et al. Analysis of erythromycin and tylosin in bovine muscle using disposable screen printed electrodes. 2004 Analyst pmid:14737577
Draisci R et al. A new electrochemical enzyme-linked immunosorbent assay for the screening of macrolide antibiotic residues in bovine meat. 2001 Analyst pmid:11763071