Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Tsinas AC et al. | Control of proliferative enteropathy in growing/fattening pigs using growth promoters. | 1998 | Zentralblatt Veterinarmedizin Reihe B | pmid:9557133 |
Norcia LJ et al. | In vitro microbiological characterization of novel macrolide CP-163,505 for animal health specific use. | 1998 | J. Antibiot. | pmid:9544934 |
Hoar BR et al. | A comparison of the clinical field efficacy and safety of florfenicol and tilmicosin for the treatment of undifferentiated bovine respiratory disease of cattle in western Canada. | 1998 | Can. Vet. J. | pmid:9524721 |
Nagaraja TG and Chengappa MM | Liver abscesses in feedlot cattle: a review. | 1998 | J. Anim. Sci. | pmid:9464910 |
Kempf I et al. | Efficacy of tilmicosin in the control of experimental Mycoplasma gallisepticum infection in chickens. | 1997 Oct-Dec | Avian Dis. | pmid:9454912 |
Yeh WK | Evolving enzyme technology for pharmaceutical applications: case studies. | 1997 Nov-Dec | J. Ind. Microbiol. Biotechnol. | pmid:9451830 |
Fish SA and Cundliffe E | Stimulation of polyketide metabolism in Streptomyces fradiae by tylosin and its glycosylated precursors. | 1997 | Microbiology (Reading, Engl.) | pmid:9421911 |
Moran JW et al. | Determination of tilmicosin in bovine and porcine sera by liquid chromatography. | 1997 Nov-Dec | J AOAC Int | pmid:9419857 |
Readnour RS et al. | Determination of tilmicosin in swine feeds by liquid chromatography. | 1997 Nov-Dec | J AOAC Int | pmid:9419854 |
Readnour RS et al. | Liquid chromatographic determination of tilmicosin in swine feed at 200-400 mg/kg level: interlaboratory study. | 1997 Nov-Dec | J AOAC Int | pmid:9419853 |
Lee SH | Ammonium ion affecting tylosin production by Streptomyces fradiae NRRL 2702 in continuous culture. | 1997 | Lett. Appl. Microbiol. | pmid:9418071 |
Naranda A et al. | New dihydro and tetrahydro derivatives of desmycosin. III. The opening of oxirane ring of 12,13-epoxydesmycosin. | 1997 | J. Antibiot. | pmid:9402992 |
Residues of some veterinary drugs in animals and foods. Monographs prepared by the Forty-Seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives. Rome, 4-13 June 1996. | 1997 | FAO Food Nutr Pap | pmid:9253593 | |
Morck DW et al. | Treatment of experimentally induced pneumonic pasteurellosis of young calves with tilmicosin. | 1997 | Can. J. Vet. Res. | pmid:9242998 |
Mironov VA et al. | [Effect of Ca2+ ions on biosynthesis and component composition of tylosin in Streptomyces fradiae]. | 1997 | Antibiot. Khimioter. | pmid:9182505 |
Ramadan A | Pharmacokinetics of tilmicosin in serum and milk of goats. | 1997 Jan-Feb | Res. Vet. Sci. | pmid:9160424 |
Memili E and Weisblum B | Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae. | 1997 | Antimicrob. Agents Chemother. | pmid:9145902 |
McFarland JW et al. | Quantitative structure-activity relationships among macrolide antibacterial agents: in vitro and in vivo potency against Pasteurella multocida. | 1997 | J. Med. Chem. | pmid:9135031 |
McFarland JW et al. | Repromicin derivatives with potent antibacterial activity against Pasteurella multocida. | 1997 | J. Med. Chem. | pmid:9083494 |
Baltz RH et al. | Applications of transposition mutagenesis in antibiotic producing streptomycetes. | 1997 | Antonie Van Leeuwenhoek | pmid:9049029 |