Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Tylosin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Rose M et al. | Pharmacokinetics of tildipirosin in porcine plasma, lung tissue, and bronchial fluid and effects of test conditions on in vitro activity against reference strains and field isolates of Actinobacillus pleuropneumoniae. | 2013 | J. Vet. Pharmacol. Ther. | pmid:22500881 |
Whitehead TR and Cotta MA | Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. | 2013 | Lett. Appl. Microbiol. | pmid:23297734 |
Hao H et al. | Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. | 2013 | Antimicrob. Agents Chemother. | pmid:23274667 |
Tsutsui A et al. | Antimalarial C-9 oxime derivatives from desmycosin, produced by click chemistry. | 2013 | J. Antibiot. | pmid:23232930 |
Burkin MA and Galvidis IA | Hapten modification approach for switching immunoassay specificity from selective to generic. | 2013 | J. Immunol. Methods | pmid:23234756 |
Holman DB and Chénier MR | Impact of subtherapeutic administration of tylosin and chlortetracycline on antimicrobial resistance in farrow-to-finish swine. | 2013 | FEMS Microbiol. Ecol. | pmid:23397987 |
Ali M et al. | Effect of redox potential and pH status on degradation and adsorption behavior of tylosin in dairy lagoon sediment suspension. | 2013 | Chemosphere | pmid:23352520 |
Gaudin V et al. | Validation of two ELISA kits for the screening of tylosin and streptomycin in honey according to the European decision 2002/657/EC. | 2013 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:23013044 |
Devreese M et al. | An in vitro model using the IPEC-J2 cell line for efficacy and drug interaction testing of mycotoxin detoxifying agents. | 2013 | Toxicol In Vitro | pmid:23078954 |
Pan R et al. | Extraction of trace tilmicosin in real water samples using ionic liquid-based aqueous two-phase systems. | 2013 | Water Sci. Technol. | pmid:23579819 |
Zhang Q et al. | Sorption of tylosin on clay minerals. | 2013 | Chemosphere | pmid:24007614 |
GarcÃa-Sánchez L et al. | Occurrence of tylosin in swine wastewater in Mexico. | 2013 | Water Sci. Technol. | pmid:23985521 |
Svartström O et al. | Characterization of Treponema spp. isolates from pigs with ear necrosis and shoulder ulcers. | 2013 | Vet. Microbiol. | pmid:23948134 |
Herd MB et al. | Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. | 2013 | J. Neurosci. | pmid:24027285 |
Corns SM et al. | Development of antibiotic regimens using graph based evolutionary algorithms. | 2013 | BioSystems | pmid:24051263 |
Stackhouse-Lawson KR et al. | Growth promoting technologies reduce greenhouse gas, alcohol, and ammonia emissions from feedlot cattle. | 2013 | J. Anim. Sci. | pmid:24085413 |
Mitchell SM et al. | The effects of the antibiotics ampicillin, florfenicol, sulfamethazine, and tylosin on biogas production and their degradation efficiency during anaerobic digestion. | 2013 | Bioresour. Technol. | pmid:24113548 |
Lin J et al. | Response of intestinal microbiota to antibiotic growth promoters in chickens. | 2013 | Foodborne Pathog. Dis. | pmid:23461609 |
Shishkina A et al. | Conjugates of amino acids and peptides with 5-o-mycaminosyltylonolide and their interaction with the ribosomal exit tunnel. | 2013 | Bioconjug. Chem. | pmid:24090034 |
Pilcher CM et al. | Impact of tylosin phosphate and distillers dried grains with solubles on energy and nutrient digestibility and flow through the gastrointestinal tract in growing pigs. | 2013 | J. Anim. Sci. | pmid:24126274 |