Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Holman DB and Chénier MR Temporal changes and the effect of subtherapeutic concentrations of antibiotics in the gut microbiota of swine. 2014 FEMS Microbiol. Ecol. pmid:25187398
Avci T and Elmas M Milk and blood pharmacokinetics of tylosin and tilmicosin following parenteral administrations to cows. 2014 ScientificWorldJournal pmid:25177733
Kilpinen S et al. Efficacy of two low-dose oral tylosin regimens in controlling the relapse of diarrhea in dogs with tylosin-responsive diarrhea: a prospective, single-blinded, two-arm parallel, clinical field trial. 2014 Acta Vet. Scand. pmid:25096196
Chen X et al. Preparation and evaluation of tilmicosin-loaded hydrogenated castor oil nanoparticle suspensions of different particle sizes. 2014 Int J Nanomedicine pmid:24920902
Beck P et al. Additive effects of growth promoting technologies on performance of grazing steers and economics of the wheat pasture enterprise. 2014 J. Anim. Sci. pmid:24492552
Kawai K et al. Antimicrobial susceptibilities of Mycoplasma isolated from bovine mastitis in Japan. 2014 Anim. Sci. J. pmid:24261609
Marosevic D et al. In vivo spread of macrolide-lincosamide-streptogramin B (MLSB) resistance--a model study in chickens. 2014 Vet. Microbiol. pmid:24467930
Usui M et al. Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. 2014 Vet. Rec. pmid:25163817
Tavío MM et al. In vitro activity of tylvalosin against Spanish field strains of Mycoplasma hyopneumoniae. 2014 Vet. Rec. pmid:25185108
Solliec M et al. Analysis of trimethoprim, lincomycin, sulfadoxin and tylosin in swine manure using laser diode thermal desorption-atmospheric pressure chemical ionization-tandem mass spectrometry. 2014 Talanta pmid:25059125
Sehati N et al. Extraction and preconcentration of tylosin from milk samples through functionalized TiOâ‚‚ nanoparticles reinforced with a hollow fiber membrane as a novel solid/liquid-phase microextraction technique. 2014 J Sep Sci pmid:24890459
Ferrag-Siagh F et al. Electro-Fenton pretreatment for the improvement of tylosin biodegradability. 2014 Environ Sci Pollut Res Int pmid:24705893
Entorf M et al. Tylosin susceptibility of Staphylococci from bovine mastitis. 2014 Vet. Microbiol. pmid:24461550
Ji LW et al. Comparative pharmacokinetics and bioavailability of tylosin tartrate and tylosin phosphate after a single oral and i.v. administration in chickens. 2014 J. Vet. Pharmacol. Ther. pmid:24325541
Guo X et al. The influences of pH and ionic strength on the sorption of tylosin on goethite. 2014 Environ Sci Pollut Res Int pmid:24197966
Pei Z et al. Effects of copper and aluminum on the adsorption of sulfathiazole and tylosin on peat and soil. 2014 Environ. Pollut. pmid:24201036
Khaliq S et al. Characterization of mutations in regulatory genes of Tyl cluster leading to overexpression of tylosin in mutant γ-1 of Streptomyces fradiae NRRL-2702. 2014 Appl. Microbiol. Biotechnol. pmid:24270892
Kolanović BS et al. Tylosin content in meat and honey samples over a two-year period in Croatia. 2014 J Immunoassay Immunochem pmid:24063615
Zhao Z et al. Tylvalosin exhibits anti-inflammatory property and attenuates acute lung injury in different models possibly through suppression of NF-κB activation. 2014 Biochem. Pharmacol. pmid:24792436
VoeÄ­kova TA et al. [Bion-M1. Biological activities of microorganisms under the conditions of a 30-day space flight]. 2014 Aviakosm Ekolog Med pmid:25365877
Kim HB et al. Effects of tylosin administration on C-reactive protein concentration and carriage of Salmonella enterica in pigs. 2014 Am. J. Vet. Res. pmid:24762018
Muñoz R et al. Withdrawal times of oxytetracycline and tylosin in eggs of laying hens after oral administration. 2014 J. Food Prot. pmid:24853528
Xia X et al. Proteomic analysis of tylosin-resistant Mycoplasma gallisepticum reveals enzymatic activities associated with resistance. 2015 Sci Rep pmid:26584633
Lu C et al. Identification of novel tylosin analogues generated by a wblA disruption mutant of Streptomyces ansochromogenes. 2015 Microb. Cell Fact. pmid:26525981
Nobel YR et al. Metabolic and metagenomic outcomes from early-life pulsed antibiotic treatment. 2015 Nat Commun pmid:26123276
Maxwell CL et al. The effects of technology use in feedlot production systems on feedlot performance and carcass characteristics. 2015 J. Anim. Sci. pmid:26020911
Pilcher CM et al. The interaction of fiber, supplied by distillers dried grains with solubles, with an antimicrobial and a nutrient partitioning agent on nitrogen balance, water utilization, and energy digestibility in finishing pigs. 2015 J. Anim. Sci. pmid:26020889
Mercadante VR et al. Effects of anti-phospholipase A(2) antibody supplementation on dry matter intake feed efficiency, acute phase response, and blood differentials of steers fed forage- and grain-based diets. 2015 J. Anim. Sci. pmid:26020758
Lysnyansky I et al. Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. 2015 Microb. Drug Resist. pmid:25734368
Luo H et al. Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. 2015 Avian Pathol. pmid:25690020
Dieste-Pérez L et al. Studies on a suitable antibiotic therapy for treating swine brucellosis. 2015 J. Vet. Pharmacol. Ther. pmid:25413993
Amachawadi RG et al. Effects of In-Feed Copper, Chlortetracycline, and Tylosin on the Prevalence of Transferable Copper Resistance Gene, tcrB, Among Fecal Enterococci of Weaned Piglets. 2015 Foodborne Pathog. Dis. pmid:26258261
Sura S et al. Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff. 2015 Sci. Total Environ. pmid:25839178
Sehati N et al. Application of hollow fiber membrane mediated with titanium dioxide nanowire/reduced graphene oxide nanocomposite in preconcentration of clotrimazole and tylosin. 2015 J Chromatogr A pmid:26477522
Blondeau JM et al. Bactericidal effects of various concentrations of enrofloxacin, florfenicol, tilmicosin phosphate, and tulathromycin on clinical isolates of Mannheimia haemolytica. 2015 Am. J. Vet. Res. pmid:26413823
Hao H et al. Microbiological toxicity of tilmicosin on human colonic microflora in chemostats. 2015 Regul. Toxicol. Pharmacol. pmid:26190303
Kilpinen S et al. Oral tylosin administration is associated with an increase of faecal enterococci and lactic acid bacteria in dogs with tylosin-responsive diarrhoea. 2015 Vet. J. pmid:26049259
Whitehead TR et al. Savagea faecisuis gen. nov., sp. nov., a tylosin- and tetracycline-resistant bacterium isolated from a swine-manure storage pit. 2015 Antonie Van Leeuwenhoek pmid:25980832
Li Q et al. Co-addition of manure increases the dissipation rates of tylosin A and the numbers of resistance genes in laboratory incubation experiments. 2015 Sci. Total Environ. pmid:25958362
Le T et al. A quantum dot-based immunoassay for screening of tylosin and tilmicosin in edible animal tissues. 2015 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:25822697
Amachawadi RG et al. Effects of in-feed copper and tylosin supplementations on copper and antimicrobial resistance in faecal enterococci of feedlot cattle. 2015 J. Appl. Microbiol. pmid:25739516
Mitchell SM et al. Hydrolysis of amphenicol and macrolide antibiotics: Chloramphenicol, florfenicol, spiramycin, and tylosin. 2015 Chemosphere pmid:25618189
Li Y et al. Effects of Cu exposure on enzyme activities and selection for microbial tolerances during swine-manure composting. 2015 J. Hazard. Mater. pmid:25464290
Abdel-Daim MM et al. Synergistic protective role of mirazid (Commiphora molmol) and ascorbic acid against tilmicosin-induced cardiotoxicity in mice. 2015 Can. J. Physiol. Pharmacol. pmid:25429612
Zhu H et al. Immobilization of Streptomyces thermotolerans 11432 on polyurethane foam to improve production of acetylisovaleryltylosin. 2015 J. Ind. Microbiol. Biotechnol. pmid:25413211
Tereshchenkov AG et al. New Fluorescent Macrolide Derivatives for Studying Interactions of Antibiotics and Their Analogs with the Ribosomal Exit Tunnel. 2016 Biochemistry Mosc. pmid:27908240
Luby EM et al. Fate and transport of tylosin-resistant bacteria and macrolide resistance genes in artificially drained agricultural fields receiving swine manure. 2016 Sci. Total Environ. pmid:26874610
Rose M et al. A microbiological assay to estimate the antimicrobial activity of parenteral tildipirosin against foodborne pathogens and commensals in the colon of beef cattle and pigs. 2016 J. Vet. Pharmacol. Ther. pmid:26538405
El-Mahmoudy A and Gheith I The anti-nociceptive potential of tilmicosin against chemical-induced but not thermal-induced pain in mice. 2016 Int J Immunopathol Pharmacol pmid:26519523
Entorf M et al. Comparative erythromycin and tylosin susceptibility testing of streptococci from bovine mastitis. 2016 Vet. Microbiol. pmid:26732695