| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid:7756878 | ||||
| Zhang AJ and Warshaw EM | Pet Consort Dermatitis: The Importance of Asking About Pets. | Dermatitis | pmid:29901502 | |
| Yahiaoui I et al. | Removal of a mixture tetracycline-tylosin from water based on anodic oxidation on a glassy carbon electrode coupled to activated sludge. | Environ Technol | pmid:25650749 | |
| Topp E et al. | Accelerated Biodegradation of Veterinary Antibiotics in Agricultural Soil following Long-Term Exposure, and Isolation of a Sulfamethazine-degrading sp. | J. Environ. Qual. | pmid:23673752 | |
| pmid: | ||||
| DENNY CB et al. | Effects of tylosin and nisin on canned food spoilage bacteria. | 1961 | Appl Microbiol | pmid:13721908 |
| DOORNENBAL H | CLINICAL EVALUATION OF TYLOSIN AS A TREATMENT OF VIBRIONIC DYSENTERY IN SWINE. | 1965 | Can J Comp Med Vet Sci | pmid:14300858 |
| Shimi IR et al. | Staphcoccomycin, a new basic macrolide antibiotic. | 1979 | J. Antibiot. | pmid:541251 |
| Omura S et al. | X-ray crystallography of protylonolide and absolute configuration of tylosin. | 1980 | J. Antibiot. | pmid:7429997 |
| Inouye S et al. | Modifications of a macrolide antibiotic midecamycin. II. Reaction of midecamycin and 9-acetylmidecamycin with dimethylsulfoxide and acetic anhydride. | 1980 | J. Antibiot. | pmid:7372551 |
| Tsuchiya M et al. | Studies on the effects of 3-acetyl-4"-isovaleryltylosin against multiple-drug resistant strains of Staphylococcus aureus. | 1981 | J. Antibiot. | pmid:7275812 |
| Seno ET and Baltz RH | Properties of S-adenosyl-L-methionine:macrocin O-methyltransferase in extracts of Streptomyces fradiae strains which produce normal or elevated levels of tylosin and in mutants blocked in specific O-methylations. | 1981 | Antimicrob. Agents Chemother. | pmid:7305323 |
| Tanaka A et al. | Synthesis of 4'-deoxymycaminosyl tylonolide. | 1981 | J. Antibiot. | pmid:7309633 |
| Tanaka A et al. | Syntheses of derivatives of 4'-deoxymycaminosyl tylonolide and mycaminosyl tylonolide modified AT C-23. | 1981 | J. Antibiot. | pmid:7309634 |
| Tanaka A et al. | Syntheses of 4'-deoxy-demycarosyl tylosin and its analogues. | 1981 | J. Antibiot. | pmid:7309635 |
| Hopper RJ and Miller ML | Efficacy of swine erysipelas vaccine given simultaneously with medicated rations. | 1981 | Vet Med Small Anim Clin | pmid:6916559 |
| Allan EM and Pirie HM | In vitro activity of tiamulin against bovine respiratory tract mycoplasmas. | 1981 | Res. Vet. Sci. | pmid:7323463 |
| Voeten AC and Litjens JB | The hygienic treatment of turkey eggs by dipping in an antibiotic and disinfectant solution. | 1982 | Vet Q | pmid:7112889 |
| Tsuchiya M et al. | Binding of 3-O-acetyl-4"-O-isovaleryltylosin to ribosomes from a macrolide-resistant strain of Staphylococcus aureus. | 1982 | J. Antibiot. | pmid:7118723 |
| Sadakane N et al. | Hybrid biosynthesis of derivatives of protylonolide and M-4365 by macrolide-producing microorganisms. | 1982 | J. Antibiot. | pmid:7118724 |
| Omura S et al. | Biosynthesis of tylosin: oxidations of 5-O-mycaminosylprotylonolide at C-20 and C-23 with a cell-free extract from Streptomyces fradiae. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7126228 |
| Vaughan RW et al. | Isolation and characterization of two 16-membered lactones: 20-deoxorosaramicin and 20-deoxo-12,13-desepoxy-12,13-dehydrorosaramicin aglycones, from a mutant strain of Micromonospora rosaria. | 1982 | J. Antibiot. | pmid:7076570 |
| Donev B et al. | [Intramammary drug forms of neotil in treating mastitis during lactation]. | 1982 | Vet Med Nauki | pmid:7157656 |
| Omura S et al. | Novel dimeric derivatives of leucomycins and tylosin, sixteen-membered macrolides. | 1982 | J. Med. Chem. | pmid:7040661 |
| Shiel MJ et al. | Polyarthritis in a calf associated with a group 7 Mycoplasma infection. | 1982 | Aust. Vet. J. | pmid:6892005 |
| Hannan PC et al. | Tylosin tartrate and tiamutilin effects on experimental piglet pneumonia induced with pneumonic pig lung homogenate containing mycoplasmas, bacteria and viruses. | 1982 | Res. Vet. Sci. | pmid:7134653 |
| Carpenter TE et al. | The effect of Mycoplasma meleagridis infection and egg dipping on the weight-gain performance of turkey poults. | 1982 Apr-Jun | Avian Dis. | pmid:7103888 |
| Simpson EJ et al. | A simple method for the removal of mycoplasma contamination from paramyxovirus stocks. | 1983 | J. Virol. Methods | pmid:6190834 |
| Jung HD | [Occupationally-induced contact eczema by tylosin (Tylan)]. | 1983 | Dermatol Monatsschr | pmid:6222923 |
| Baltz RH et al. | Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin. | 1983 | J. Antibiot. | pmid:6833128 |
| Omura S et al. | Chimeramycins: new macrolide antibiotics produced by hybrid biosynthesis. | 1983 | J. Antibiot. | pmid:6860432 |
| Kreisner M and Kietzmann M | [Pharmacokinetics of chloramphenicol, tylosin and prednisolone in combined preparations. 1. Thin-layer chromatographic determination of chloramphenicol, tylosin and prednisolone in serum]. | 1983 | Zentralbl Veterinarmed A | pmid:6407241 |
| Kietzmann M and Kreisner M | [Pharmacokinetics of chloramphenicol and tylosin in combined preparations. 2. Pharmacokinetic interaction between chloramphenicol and tylosin in calves and rats]. | 1983 | Zentralbl Veterinarmed A | pmid:6407242 |
| Dilov P et al. | [Toxicity, tolerance and blood concentrations of iron and tylosin with the use of preparation FV-82]. | 1983 | Vet Med Nauki | pmid:6623919 |
| Worseck M et al. | [Activity and minimal inhibitory concentration of turimycin against important pathogens in veterinary medicine]. | 1983 | Arch Exp Veterinarmed | pmid:6651443 |
| Hoffmann H et al. | [Antimicrobial activity in tissues of swine following subcutaneous administration of turimycin]. | 1983 | Arch Exp Veterinarmed | pmid:6651444 |
| Thurman GD et al. | Diagnosis and successful treatment of subacute erysipelas in a captive dolphin. | 1983 | J S Afr Vet Assoc | pmid:6655661 |
| Donev B et al. | [Toxicological studies of a combination of technical tylosin phosphate with bentonite (farmazin TB)]. | 1983 | Vet Med Nauki | pmid:6659350 |
| Omura S et al. | Ribosome-binding activities and antimicrobial activities of tylosin and its related compounds. | 1983 | J. Antibiot. | pmid:6662812 |
| Matsubara H et al. | Chemical modification of tylosin: synthesis of amino derivatives at C-20 position of tylosin and demycarosyltylosin. | 1983 | J. Antibiot. | pmid:6662813 |
| Omura S et al. | Ammonium ion suppresses the biosynthesis of tylosin aglycone by interference with valine catabolism in Streptomyces fradiae. | 1983 | J. Antibiot. | pmid:6662823 |
| Truscott RB | Factors associated with the determination of antibiotic activity in bovine semen. | 1983 | Can. J. Comp. Med. | pmid:6230144 |
| Lee BK et al. | Multistep bioconversion of 20-deoxo-20-dihydro-12,13-deepoxy-12,13-dehydrorosaranolide to 22-hydroxy-23-O-mycinosyl-20-deoxo-20-dihydro-12,13-deepoxy-rosaramicin. | 1983 | J. Antibiot. | pmid:6874596 |
| Sadakane N et al. | Hybrid biosynthesis of a new macrolide antibiotic by a daunomycin-producing microorganism. | 1983 | J. Antibiot. | pmid:6885644 |
| Omura S et al. | Valine as a precursor of n-butyrate unit in the biosynthesis of macrolide aglycone. | 1983 | J. Antibiot. | pmid:6874580 |
| Wayner EA and Brooks CG | Induction of NKCF-like activity in mixed lymphocyte-tumor cell culture: direct involvement of mycoplasma infection of tumor cells. | 1984 | J. Immunol. | pmid:6230401 |
| Truscott RB and Ruhnke HL | The effect of antibiotics against bovine mycoplasmas and ureaplasmas. | 1984 | Can. J. Comp. Med. | pmid:6232992 |
| Stipkovits L et al. | Efficacy of lasalocid sodium against mycoplasmas (preliminary communication). | 1984 | Acta Vet. Hung. | pmid:6242271 |
| Omura S et al. | Ammonium ions suppress the amino acid metabolism involved in the biosynthesis of protylonolide in a mutant of Streptomyces fradiae. | 1984 | J. Antibiot. | pmid:6511663 |
| Stipkovits L et al. | A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas. | 1984 | Vet. Microbiol. | pmid:6730305 |
| Dotzlaf JE et al. | Incorporation of amino acid-derived carbon into tylactone by Streptomyces fradiae GS14. | 1984 | Antimicrob. Agents Chemother. | pmid:6424562 |
| Mackinnon JD et al. | Effect of tylosin on milk yield and dry matter intake of lactating dairy cows. | 1984 | Vet. Rec. | pmid:6495581 |
| Omura S et al. | Chemical modification of tylosin. Thioether derivatives of tylosin and demycarosyltylosin. | 1984 | J. Antibiot. | pmid:6501102 |
| Dilov P et al. | [Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs]. | 1984 | Vet Med Nauki | pmid:6474828 |
| Sakamoto S et al. | Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide. | 1984 | J. Antibiot. | pmid:6526731 |
| Mutoh Y et al. | Deepoxidation of 16-membered epoxyenone macrolide antibiotics. II. Chemical deepoxidation by dissolving metal reduction. | 1984 | J. Antibiot. | pmid:6706848 |
| Sakamoto M et al. | Deepoxidation of 16-membered epoxyenone macrolide antibiotics. III. In vitro and in vivo evaluation of deepoxidation products of carbomycin A, deltamycin A1, 4"-phenylacetyldeltamycin, angolamycin and rosamicin. | 1984 | J. Antibiot. | pmid:6706849 |
| Dafwang II et al. | Broiler chick growth response to antibiotics, 1981-1982. | 1984 | Poult. Sci. | pmid:6610176 |
| Omura S et al. | Effect of ammonium ion, inorganic phosphate and amino acids on the biosynthesis of protylonolide, a precursor of tylosin aglycone. | 1984 | J. Antibiot. | pmid:6735923 |
| Goodwin RF | In vitro activity of tiamulin against porcine mycoplasmas. | 1985 | Res. Vet. Sci. | pmid:3975477 |
| Kietzmann M | [Comparative study of the distribution and excretion of tylosin of various origins]. | 1985 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:3899580 |
| Itoh Z et al. | Structure-activity relation among macrolide antibiotics in initiation of interdigestive migrating contractions in the canine gastrointestinal tract. | 1985 | Am. J. Physiol. | pmid:3976891 |
| Brumm MC and Peo ER | Effect of receiving diets containing alfalfa and certain feed additives on performance of feeder pigs transported long distances. | 1985 | J. Anim. Sci. | pmid:4030523 |
| Tejedor F and Ballesta JP | Components of the macrolide binding site on the ribosome. | 1985 | J. Antimicrob. Chemother. | pmid:4055551 |
| Baltz RH and Stonesifer J | Phenotypic changes associated with loss of expression of tylosin biosynthesis and resistance genes in Streptomyces fradiae. | 1985 | J. Antibiot. | pmid:4066505 |
| Duthu GS | Interspecies correlation of the pharmacokinetics of erythromycin, oleandomycin, and tylosin. | 1985 | J Pharm Sci | pmid:4067847 |
| Potter EL et al. | Effect of monensin and tylosin on average daily gain, feed efficiency and liver abscess incidence in feedlot cattle. | 1985 | J. Anim. Sci. | pmid:4077750 |
| Moats WA et al. | Comparison of liquid chromatographic and bioassay procedures for determining depletion of intramuscularly injected tylosin. | 1985 May-Jun | J Assoc Off Anal Chem | pmid:4019360 |
| Moats WA | Chromatographic methods for determination of macrolide antibiotic residues in tissues and milk of food-producing animals. | 1985 Sep-Oct | J Assoc Off Anal Chem | pmid:4055648 |
| Tanaka Y et al. | Mechanism of nitrogen regulation of protylonolide biosynthesis in Streptomyces fradiae. | 1986 | J. Antibiot. | pmid:3733529 |
| Fish BJ and Carr GP | Pharmacopoeial procedure for the determination of tylosin factors by high-performance liquid chromatography. | 1986 | J. Chromatogr. | pmid:3700523 |
| Jacks TM et al. | 3-Acetyl-4''-isovaleryl tylosin for prevention of swine dysentery. | 1986 | Am. J. Vet. Res. | pmid:3789492 |
| Burrows GE et al. | Antibiotic disposition in experimental pneumonic pasteurellosis: gentamicin and tylosin. | 1986 | Can. J. Vet. Res. | pmid:3756673 |
| Tsuzuki K et al. | Syntheses and antimicrobial activities of 9-O-acyl derivatives of tylosin and demycarosyltylosin. | 1986 | J. Antibiot. | pmid:3818453 |
| Effect of space allowance and tylosin feeding on performance of growing-finishing pigs. NCR-89 Committee on Confinement Management of Swine. | 1986 | J. Anim. Sci. | pmid:3710927 | |
| Stonesifer J et al. | High frequency conjugal transfer of tylosin genes and amplifiable DNA in Streptomyces fradiae. | 1986 | Mol. Gen. Genet. | pmid:3458997 |
| el-Sayed MG et al. | Pharmacokinetic profile of tylosin in mastitic cows. | 1986 | DTW. Dtsch. Tierarztl. Wochenschr. | pmid:3530702 |
| Gershon P and Howells RE | Synergy of four macrolide antibiotics with chloroquine against chloroquine-resistant Plasmodium falciparum in vitro. | 1986 | Trans. R. Soc. Trop. Med. Hyg. | pmid:3299891 |
| Moats WA | Effect of the silica support of bonded reversed-phase columns on chromatography of some antibiotic compounds. | 1986 | J. Chromatogr. | pmid:3023412 |
| Skelly BJ et al. | Prophylactic efficacy of 3-acetyl-4''-isovaleryl tylosin in a Mycoplasma gallisepticum-induced airsacculitis infection. | 1986 Jul-Sep | Avian Dis. | pmid:3767811 |
| Cummings TS et al. | Effect of medicated feed on tracheal infection and population of Mycoplasma gallisepticum in chickens. | 1986 Jul-Sep | Avian Dis. | pmid:3767816 |
| Stipkovits L et al. | In vitro testing of the anti-mycoplasma effect of some anti-coccidial drugs. | 1987 | Vet. Microbiol. | pmid:3439016 |
| Blaha T et al. | Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. | 1987 | Vet. Rec. | pmid:3424604 |
| Rodionova II et al. | [Effect of protoplast formation on the antibiotic activity of the Streptomyces fradiae 165 strain--a producer of tylosin]. | 1987 | Antibiot. Med. Biotekhnol. | pmid:2830838 |
| Kaukas A et al. | The effect of ampicillin and tylosin on the faecal enterococci of healthy young chickens. | 1987 | J. Appl. Bacteriol. | pmid:3112089 |
| Nagaraja TG and Taylor MB | Susceptibility and resistance of ruminal bacteria to antimicrobial feed additives. | 1987 | Appl. Environ. Microbiol. | pmid:3116929 |
| Fishman SE et al. | Cloning genes for the biosynthesis of a macrolide antibiotic. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3479787 |
| Ose EE | In vitro antibacterial properties of EL-870, a new semi-synthetic macrolide antibiotic. | 1987 | J. Antibiot. | pmid:3570967 |
| Wiley PF et al. | Enzymatic phosphorylation of macrolide antibiotics. | 1987 | J. Antibiot. | pmid:3570968 |
| Kiyoshima K et al. | New tylosin analogs produced by mutants of Streptomyces fradiae. | 1987 | J. Antibiot. | pmid:3680024 |
| Takeuchi T et al. | 4''-O-(4-methoxyphenyl)-acetyltylosin, a new macrolide derivative of therapeutic importance. | 1987 | J. Antibiot. | pmid:3680047 |
| Greer RT and Ryoo JP | Development of ocular inserts for cattle. | 1987 | Scanning Microsc. | pmid:3616580 |
| Ball HJ and McCaughey WJ | Experimental intramuscular inoculation of tylosin in the elimination of ureaplasmas from ewes. | 1987 | Vet. Rec. | pmid:3617407 |
| Westerbeek JA and Jaartsveld FH | [Mycoplasma infection on a cattle farm]. | 1987 | Tijdschr Diergeneeskd | pmid:3603536 |
| Vancura A et al. | Fatty acids and production of tylosin-like compounds in Streptomyces fradiae. | 1987 | J. Basic Microbiol. | pmid:3625475 |
| Bauer NJ et al. | Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine:macrocin O-methyltransferase from Streptomyces fradiae. | 1988 | J. Biol. Chem. | pmid:3170601 |
| Kreuzman AJ et al. | Two distinctive O-methyltransferases catalyzing penultimate and terminal reactions of macrolide antibiotic (tylosin) biosynthesis. Substrate specificity, enzyme inhibition, and kinetic mechanism. | 1988 | J. Biol. Chem. | pmid:3170602 |
| Kirst HA et al. | Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics. | 1988 | J. Med. Chem. | pmid:3398001 |
| Kirst HA et al. | In vitro and in vivo evaluation of C-20- and C-23-modified derivatives of tylosin against veterinary pathogens. | 1988 | J. Antibiot. | pmid:3417566 |
| Ose EE and Tonkinson LV | Single-dose treatment of neonatal calf pneumonia with the new macrolide antibiotic tilmicosin. | 1988 | Vet. Rec. | pmid:3195026 |