| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Coleman MR et al. | The need for larger analytical samples with granulated feed additives. | 1993 Sep-Oct | J AOAC Int | pmid:8241822 |
| Scott PR | Field study of undifferentiated respiratory disease in housed beef calves. | 1994 | Vet. Rec. | pmid:8203107 |
| Chan W et al. | Determination of tylosin and tilmicosin residues in animal tissues by reversed-phase liquid chromatography. | 1994 Mar-Apr | J AOAC Int | pmid:8199468 |
| Danese P et al. | Occupational contact dermatitis from tylosin. | 1994 | Contact Derm. | pmid:8187499 |
| Coronato S et al. | A simple method to eliminate mycoplasma from cell cultures. | 1994 | J. Virol. Methods | pmid:8175949 |
| Inouye M et al. | Cloning and sequences of two macrolide-resistance-encoding genes from mycinamicin-producing Micromonospora griseorubida. | 1994 | Gene | pmid:8163173 |
| Tan ZL et al. | Serum neutralizing antibodies against Fusobacterium necrophorum leukotoxin in cattle with experimentally induced or naturally developed hepatic abscesses. | 1994 | J. Anim. Sci. | pmid:8157537 |
| Wardlaw AC et al. | Bactericidal activity in the pig roundworm Ascaris suum. | 1994 | J. Appl. Bacteriol. | pmid:8144403 |
| Hartman EG and Geryl J | Comparison between the minimal inhibitory concentration of tilmicosin and oxytetracycline for bovine pneumonic Pasteurella haemolytica isolates. | 1993 | Vet Q | pmid:8122359 |
| Fodor L et al. | Treatment of calf pneumonia with tilmicosin. | 1993 | Acta Vet. Hung. | pmid:8116500 |
| Arisawa A et al. | Cloning of the macrolide antibiotic biosynthesis gene acyA, which encodes 3-O-acyltransferase, from Streptomyces thermotolerans and its use for direct fermentative production of a hybrid macrolide antibiotic. | 1994 | Appl. Environ. Microbiol. | pmid:8074537 |
| Riddell KP et al. | Antibiotic treatment of bovine embryos. | 1993 | J. Assist. Reprod. Genet. | pmid:8069094 |
| Narandja A et al. | Structure-activity relationship among polyhydro derivatives of tylosin. | 1994 | J. Antibiot. | pmid:8040056 |
| Kounenis G et al. | Comparative study of erythromycin, troleandomycin and tylosin on the rabbit intestine. | 1994 | Fundam Clin Pharmacol | pmid:8020874 |
| Duff GC et al. | Effects of lasalocid and monensin plus tylosin on serum metabolic hormones and clinical chemistry profiles of beef steers fed a 90% concentrate diet. | 1994 | J. Anim. Sci. | pmid:8014140 |
| Scott DW et al. | Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1994 | Can. Vet. J. | pmid:7994702 |
| Trovatelli LD et al. | The effect of some antibiotics on Enterococcus faecium SF 68 inoculated in germ-free mice. | 1994 | Microbiol. Res. | pmid:7987613 |
| Merson-Davies LA and Cundliffe E | Analysis of five tylosin biosynthetic genes from the tyllBA region of the Streptomyces fradiae genome. | 1994 | Mol. Microbiol. | pmid:7984112 |
| McGuigan MA | Human exposures to tilmicosin (MICOTIL). | 1994 | Vet Hum Toxicol | pmid:7975134 |
| Buller NB and Hampson DJ | Antimicrobial susceptibility testing of Serpulina hyodysenteriae. | 1994 | Aust. Vet. J. | pmid:7945100 |
| Tang L et al. | Amino acid catabolism and antibiotic synthesis: valine is a source of precursors for macrolide biosynthesis in Streptomyces ambofaciens and Streptomyces fradiae. | 1994 | J. Bacteriol. | pmid:7928973 |
| Kageyama S and Tsuchiya T | Synthesis of 2-C-methyl derivatives of 3,4'-dideoxymycaminosyltylonolide, a novel type of 16-membered macrolide antibiotic. | 1994 | J. Antibiot. | pmid:7928687 |
| Delepine B et al. | Identification of tylosin in bovine muscle at the maximum residue limit level by liquid chromatography-mass spectrometry, using a particle beam interface. | 1994 | Analyst | pmid:7879883 |
| Parker RM and Patel RK | Determination of tilmicosin in ovine milk using high-performance liquid chromatography. | 1994 | Analyst | pmid:7879857 |
| Caraffini S et al. | Tylosin, an airborne contact allergen in veterinarians. | 1994 | Contact Derm. | pmid:7867337 |
| Inamoto T et al. | Antibacterial activity of tilmicosin against Pasteurella multocida and Actinobacillus pleuropneumoniae isolated from pneumonic lesions in swine. | 1994 | J. Vet. Med. Sci. | pmid:7865594 |
| Ueda Y et al. | Effect of terdecamycin on experimentally induced Mycoplasma hyopneumoniae-infection in pigs. | 1994 | Zentralblatt Veterinarmedizin Reihe B | pmid:7839749 |
| Shryock TR et al. | Effect of bentonite incorporated in a feed ration with tilmicosin in the prevention of induced Mycoplasma gallisepticum airsacculitis in broiler chickens. | 1994 Jul-Sep | Avian Dis. | pmid:7832702 |
| Kirchgessner M et al. | [The effect of avilamycin and tylosin on the apparent digestibility of iron, zinc, copper, manganese and selenium in the beginning and ending performance of swine]. | 1994 | Arch Tierernahr | pmid:7778980 |
| Nguyen LT et al. | The tylosin producer, Streptomyces fradiae, contains a second valine dehydrogenase. | 1995 | Microbiology (Reading, Engl.) | pmid:7773408 |
| Lee SH and Lee KJ | Kinetics of the repression of tylosin biosynthesis by ammonium ion in Streptomyces fradiae. | 1994 | J. Biotechnol. | pmid:7764561 |
| Arisawa A et al. | Cloning and nucleotide sequences of two genes involved in the 4''-O-acylation of macrolide antibiotics from Streptomyces thermotolerans. | 1993 | Biosci. Biotechnol. Biochem. | pmid:7764361 |
| Paesen J et al. | Isolation of decomposition products of tylosin using liquid chromatography. | 1995 | J Chromatogr A | pmid:7757214 |
| pmid:7756878 | ||||
| Narandja A et al. | 10,11,12,13-Tetrahydro derivatives of tylosin. II. Synthesis, antibacterial activity and tissue of 4'-deoxy-10,11,12,13-tetrahydrodesmycosin. | 1995 | J. Antibiot. | pmid:7730160 |
| Shryock TR et al. | Proposed quality control guidelines for antimicrobial susceptibility tests using tilmicosin. | 1995 | J. Clin. Microbiol. | pmid:7714188 |
| Galyean ML et al. | Effects of arrival medication with tilmicosin phosphate on health and performance of newly received beef cattle. | 1995 | J. Anim. Sci. | pmid:7665351 |
| Creemer LC et al. | Synthesis, antimicrobial activity and in vivo fluorine NMR of a hexafluorinated derivative of tilmicosin. | 1995 | J. Antibiot. | pmid:7649867 |
| Bobillot S et al. | Chemical modification of tylosin. | 1995 | J. Antibiot. | pmid:7649866 |
| Stock RA et al. | Effect of monensin and monensin and tylosin combination on feed intake variation of feedlot steers. | 1995 | J. Anim. Sci. | pmid:7601752 |
| Harvey RB et al. | Influence of the antibiotics lincomycin and tylosin on aflatoxicosis when added to aflatoxin-contaminated diets of growing swine. | 1995 | J. Vet. Diagn. Invest. | pmid:7578454 |
| Kelemen GH et al. | Transcriptional attenuation control of the tylosin-resistance gene tlrA in Streptomyces fradiae. | 1994 | Mol. Microbiol. | pmid:7534372 |
| Omura S et al. | X-ray crystallography of protylonolide and absolute configuration of tylosin. | 1980 | J. Antibiot. | pmid:7429997 |
| Inouye S et al. | Modifications of a macrolide antibiotic midecamycin. II. Reaction of midecamycin and 9-acetylmidecamycin with dimethylsulfoxide and acetic anhydride. | 1980 | J. Antibiot. | pmid:7372551 |
| Allan EM and Pirie HM | In vitro activity of tiamulin against bovine respiratory tract mycoplasmas. | 1981 | Res. Vet. Sci. | pmid:7323463 |
| Tanaka A et al. | Syntheses of 4'-deoxy-demycarosyl tylosin and its analogues. | 1981 | J. Antibiot. | pmid:7309635 |
| Tanaka A et al. | Syntheses of derivatives of 4'-deoxymycaminosyl tylonolide and mycaminosyl tylonolide modified AT C-23. | 1981 | J. Antibiot. | pmid:7309634 |
| Tanaka A et al. | Synthesis of 4'-deoxymycaminosyl tylonolide. | 1981 | J. Antibiot. | pmid:7309633 |
| Seno ET and Baltz RH | Properties of S-adenosyl-L-methionine:macrocin O-methyltransferase in extracts of Streptomyces fradiae strains which produce normal or elevated levels of tylosin and in mutants blocked in specific O-methylations. | 1981 | Antimicrob. Agents Chemother. | pmid:7305323 |
| Tsuchiya M et al. | Studies on the effects of 3-acetyl-4"-isovaleryltylosin against multiple-drug resistant strains of Staphylococcus aureus. | 1981 | J. Antibiot. | pmid:7275812 |
| Donev B et al. | [Intramammary drug forms of neotil in treating mastitis during lactation]. | 1982 | Vet Med Nauki | pmid:7157656 |
| Hannan PC et al. | Tylosin tartrate and tiamutilin effects on experimental piglet pneumonia induced with pneumonic pig lung homogenate containing mycoplasmas, bacteria and viruses. | 1982 | Res. Vet. Sci. | pmid:7134653 |
| Omura S et al. | Biosynthesis of tylosin: oxidations of 5-O-mycaminosylprotylonolide at C-20 and C-23 with a cell-free extract from Streptomyces fradiae. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7126228 |
| Sadakane N et al. | Hybrid biosynthesis of derivatives of protylonolide and M-4365 by macrolide-producing microorganisms. | 1982 | J. Antibiot. | pmid:7118724 |
| Tsuchiya M et al. | Binding of 3-O-acetyl-4"-O-isovaleryltylosin to ribosomes from a macrolide-resistant strain of Staphylococcus aureus. | 1982 | J. Antibiot. | pmid:7118723 |
| Voeten AC and Litjens JB | The hygienic treatment of turkey eggs by dipping in an antibiotic and disinfectant solution. | 1982 | Vet Q | pmid:7112889 |
| Carpenter TE et al. | The effect of Mycoplasma meleagridis infection and egg dipping on the weight-gain performance of turkey poults. | 1982 Apr-Jun | Avian Dis. | pmid:7103888 |
| Vaughan RW et al. | Isolation and characterization of two 16-membered lactones: 20-deoxorosaramicin and 20-deoxo-12,13-desepoxy-12,13-dehydrorosaramicin aglycones, from a mutant strain of Micromonospora rosaria. | 1982 | J. Antibiot. | pmid:7076570 |
| Omura S et al. | Novel dimeric derivatives of leucomycins and tylosin, sixteen-membered macrolides. | 1982 | J. Med. Chem. | pmid:7040661 |
| Hopper RJ and Miller ML | Efficacy of swine erysipelas vaccine given simultaneously with medicated rations. | 1981 | Vet Med Small Anim Clin | pmid:6916559 |
| Shiel MJ et al. | Polyarthritis in a calf associated with a group 7 Mycoplasma infection. | 1982 | Aust. Vet. J. | pmid:6892005 |
| Sadakane N et al. | Hybrid biosynthesis of a new macrolide antibiotic by a daunomycin-producing microorganism. | 1983 | J. Antibiot. | pmid:6885644 |
| Lee BK et al. | Multistep bioconversion of 20-deoxo-20-dihydro-12,13-deepoxy-12,13-dehydrorosaranolide to 22-hydroxy-23-O-mycinosyl-20-deoxo-20-dihydro-12,13-deepoxy-rosaramicin. | 1983 | J. Antibiot. | pmid:6874596 |
| Omura S et al. | Valine as a precursor of n-butyrate unit in the biosynthesis of macrolide aglycone. | 1983 | J. Antibiot. | pmid:6874580 |
| Omura S et al. | Chimeramycins: new macrolide antibiotics produced by hybrid biosynthesis. | 1983 | J. Antibiot. | pmid:6860432 |
| Baltz RH et al. | Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin. | 1983 | J. Antibiot. | pmid:6833128 |
| Omura S et al. | Effect of ammonium ion, inorganic phosphate and amino acids on the biosynthesis of protylonolide, a precursor of tylosin aglycone. | 1984 | J. Antibiot. | pmid:6735923 |
| Stipkovits L et al. | A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas. | 1984 | Vet. Microbiol. | pmid:6730305 |
| Sakamoto M et al. | Deepoxidation of 16-membered epoxyenone macrolide antibiotics. III. In vitro and in vivo evaluation of deepoxidation products of carbomycin A, deltamycin A1, 4"-phenylacetyldeltamycin, angolamycin and rosamicin. | 1984 | J. Antibiot. | pmid:6706849 |
| Mutoh Y et al. | Deepoxidation of 16-membered epoxyenone macrolide antibiotics. II. Chemical deepoxidation by dissolving metal reduction. | 1984 | J. Antibiot. | pmid:6706848 |
| Omura S et al. | Ammonium ion suppresses the biosynthesis of tylosin aglycone by interference with valine catabolism in Streptomyces fradiae. | 1983 | J. Antibiot. | pmid:6662823 |
| Matsubara H et al. | Chemical modification of tylosin: synthesis of amino derivatives at C-20 position of tylosin and demycarosyltylosin. | 1983 | J. Antibiot. | pmid:6662813 |
| Omura S et al. | Ribosome-binding activities and antimicrobial activities of tylosin and its related compounds. | 1983 | J. Antibiot. | pmid:6662812 |
| Donev B et al. | [Toxicological studies of a combination of technical tylosin phosphate with bentonite (farmazin TB)]. | 1983 | Vet Med Nauki | pmid:6659350 |
| Thurman GD et al. | Diagnosis and successful treatment of subacute erysipelas in a captive dolphin. | 1983 | J S Afr Vet Assoc | pmid:6655661 |
| Hoffmann H et al. | [Antimicrobial activity in tissues of swine following subcutaneous administration of turimycin]. | 1983 | Arch Exp Veterinarmed | pmid:6651444 |
| Worseck M et al. | [Activity and minimal inhibitory concentration of turimycin against important pathogens in veterinary medicine]. | 1983 | Arch Exp Veterinarmed | pmid:6651443 |
| Dilov P et al. | [Toxicity, tolerance and blood concentrations of iron and tylosin with the use of preparation FV-82]. | 1983 | Vet Med Nauki | pmid:6623919 |
| Dafwang II et al. | Broiler chick growth response to antibiotics, 1981-1982. | 1984 | Poult. Sci. | pmid:6610176 |
| Sakamoto S et al. | Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide. | 1984 | J. Antibiot. | pmid:6526731 |
| Omura S et al. | Ammonium ions suppress the amino acid metabolism involved in the biosynthesis of protylonolide in a mutant of Streptomyces fradiae. | 1984 | J. Antibiot. | pmid:6511663 |
| Omura S et al. | Chemical modification of tylosin. Thioether derivatives of tylosin and demycarosyltylosin. | 1984 | J. Antibiot. | pmid:6501102 |
| Mackinnon JD et al. | Effect of tylosin on milk yield and dry matter intake of lactating dairy cows. | 1984 | Vet. Rec. | pmid:6495581 |
| Dilov P et al. | [Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs]. | 1984 | Vet Med Nauki | pmid:6474828 |
| Dotzlaf JE et al. | Incorporation of amino acid-derived carbon into tylactone by Streptomyces fradiae GS14. | 1984 | Antimicrob. Agents Chemother. | pmid:6424562 |
| Kietzmann M and Kreisner M | [Pharmacokinetics of chloramphenicol and tylosin in combined preparations. 2. Pharmacokinetic interaction between chloramphenicol and tylosin in calves and rats]. | 1983 | Zentralbl Veterinarmed A | pmid:6407242 |
| Kreisner M and Kietzmann M | [Pharmacokinetics of chloramphenicol, tylosin and prednisolone in combined preparations. 1. Thin-layer chromatographic determination of chloramphenicol, tylosin and prednisolone in serum]. | 1983 | Zentralbl Veterinarmed A | pmid:6407241 |
| Stipkovits L et al. | Efficacy of lasalocid sodium against mycoplasmas (preliminary communication). | 1984 | Acta Vet. Hung. | pmid:6242271 |
| Truscott RB and Ruhnke HL | The effect of antibiotics against bovine mycoplasmas and ureaplasmas. | 1984 | Can. J. Comp. Med. | pmid:6232992 |
| Wayner EA and Brooks CG | Induction of NKCF-like activity in mixed lymphocyte-tumor cell culture: direct involvement of mycoplasma infection of tumor cells. | 1984 | J. Immunol. | pmid:6230401 |
| Truscott RB | Factors associated with the determination of antibiotic activity in bovine semen. | 1983 | Can. J. Comp. Med. | pmid:6230144 |
| Jung HD | [Occupationally-induced contact eczema by tylosin (Tylan)]. | 1983 | Dermatol Monatsschr | pmid:6222923 |
| Simpson EJ et al. | A simple method for the removal of mycoplasma contamination from paramyxovirus stocks. | 1983 | J. Virol. Methods | pmid:6190834 |
| Shimi IR et al. | Staphcoccomycin, a new basic macrolide antibiotic. | 1979 | J. Antibiot. | pmid:541251 |
| Potter EL et al. | Effect of monensin and tylosin on average daily gain, feed efficiency and liver abscess incidence in feedlot cattle. | 1985 | J. Anim. Sci. | pmid:4077750 |
| Duthu GS | Interspecies correlation of the pharmacokinetics of erythromycin, oleandomycin, and tylosin. | 1985 | J Pharm Sci | pmid:4067847 |
| Baltz RH and Stonesifer J | Phenotypic changes associated with loss of expression of tylosin biosynthesis and resistance genes in Streptomyces fradiae. | 1985 | J. Antibiot. | pmid:4066505 |
| Moats WA | Chromatographic methods for determination of macrolide antibiotic residues in tissues and milk of food-producing animals. | 1985 Sep-Oct | J Assoc Off Anal Chem | pmid:4055648 |
| Tejedor F and Ballesta JP | Components of the macrolide binding site on the ribosome. | 1985 | J. Antimicrob. Chemother. | pmid:4055551 |
| Brumm MC and Peo ER | Effect of receiving diets containing alfalfa and certain feed additives on performance of feeder pigs transported long distances. | 1985 | J. Anim. Sci. | pmid:4030523 |