Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Kietzmann M and Kreisner M [Pharmacokinetics of chloramphenicol and tylosin in combined preparations. 2. Pharmacokinetic interaction between chloramphenicol and tylosin in calves and rats]. 1983 Zentralbl Veterinarmed A pmid:6407242
Omura S et al. Ammonium ion suppresses the biosynthesis of tylosin aglycone by interference with valine catabolism in Streptomyces fradiae. 1983 J. Antibiot. pmid:6662823
Truscott RB Factors associated with the determination of antibiotic activity in bovine semen. 1983 Can. J. Comp. Med. pmid:6230144
Lee BK et al. Multistep bioconversion of 20-deoxo-20-dihydro-12,13-deepoxy-12,13-dehydrorosaranolide to 22-hydroxy-23-O-mycinosyl-20-deoxo-20-dihydro-12,13-deepoxy-rosaramicin. 1983 J. Antibiot. pmid:6874596
Sadakane N et al. Hybrid biosynthesis of a new macrolide antibiotic by a daunomycin-producing microorganism. 1983 J. Antibiot. pmid:6885644
Wayner EA and Brooks CG Induction of NKCF-like activity in mixed lymphocyte-tumor cell culture: direct involvement of mycoplasma infection of tumor cells. 1984 J. Immunol. pmid:6230401
Truscott RB and Ruhnke HL The effect of antibiotics against bovine mycoplasmas and ureaplasmas. 1984 Can. J. Comp. Med. pmid:6232992
Stipkovits L et al. Efficacy of lasalocid sodium against mycoplasmas (preliminary communication). 1984 Acta Vet. Hung. pmid:6242271
Omura S et al. Ammonium ions suppress the amino acid metabolism involved in the biosynthesis of protylonolide in a mutant of Streptomyces fradiae. 1984 J. Antibiot. pmid:6511663
Stipkovits L et al. A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas. 1984 Vet. Microbiol. pmid:6730305
Dotzlaf JE et al. Incorporation of amino acid-derived carbon into tylactone by Streptomyces fradiae GS14. 1984 Antimicrob. Agents Chemother. pmid:6424562
Mackinnon JD et al. Effect of tylosin on milk yield and dry matter intake of lactating dairy cows. 1984 Vet. Rec. pmid:6495581
Omura S et al. Chemical modification of tylosin. Thioether derivatives of tylosin and demycarosyltylosin. 1984 J. Antibiot. pmid:6501102
Dilov P et al. [Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs]. 1984 Vet Med Nauki pmid:6474828
Sakamoto S et al. Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide. 1984 J. Antibiot. pmid:6526731
Mutoh Y et al. Deepoxidation of 16-membered epoxyenone macrolide antibiotics. II. Chemical deepoxidation by dissolving metal reduction. 1984 J. Antibiot. pmid:6706848
Sakamoto M et al. Deepoxidation of 16-membered epoxyenone macrolide antibiotics. III. In vitro and in vivo evaluation of deepoxidation products of carbomycin A, deltamycin A1, 4"-phenylacetyldeltamycin, angolamycin and rosamicin. 1984 J. Antibiot. pmid:6706849
Dafwang II et al. Broiler chick growth response to antibiotics, 1981-1982. 1984 Poult. Sci. pmid:6610176
Omura S et al. Effect of ammonium ion, inorganic phosphate and amino acids on the biosynthesis of protylonolide, a precursor of tylosin aglycone. 1984 J. Antibiot. pmid:6735923
Brumm MC and Peo ER Effect of receiving diets containing alfalfa and certain feed additives on performance of feeder pigs transported long distances. 1985 J. Anim. Sci. pmid:4030523