| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Appl. Environ. Microbiol. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- FEMS Microbiol. Lett. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Donev B et al. | [Intramammary drug forms of neotil in treating mastitis during lactation]. | 1982 | Vet Med Nauki | pmid:7157656 |
| Hannan PC et al. | Tylosin tartrate and tiamutilin effects on experimental piglet pneumonia induced with pneumonic pig lung homogenate containing mycoplasmas, bacteria and viruses. | 1982 | Res. Vet. Sci. | pmid:7134653 |
| Omura S et al. | Biosynthesis of tylosin: oxidations of 5-O-mycaminosylprotylonolide at C-20 and C-23 with a cell-free extract from Streptomyces fradiae. | 1982 | Biochem. Biophys. Res. Commun. | pmid:7126228 |
| Sadakane N et al. | Hybrid biosynthesis of derivatives of protylonolide and M-4365 by macrolide-producing microorganisms. | 1982 | J. Antibiot. | pmid:7118724 |
| Tsuchiya M et al. | Binding of 3-O-acetyl-4"-O-isovaleryltylosin to ribosomes from a macrolide-resistant strain of Staphylococcus aureus. | 1982 | J. Antibiot. | pmid:7118723 |
| Voeten AC and Litjens JB | The hygienic treatment of turkey eggs by dipping in an antibiotic and disinfectant solution. | 1982 | Vet Q | pmid:7112889 |
| Carpenter TE et al. | The effect of Mycoplasma meleagridis infection and egg dipping on the weight-gain performance of turkey poults. | 1982 Apr-Jun | Avian Dis. | pmid:7103888 |
| Vaughan RW et al. | Isolation and characterization of two 16-membered lactones: 20-deoxorosaramicin and 20-deoxo-12,13-desepoxy-12,13-dehydrorosaramicin aglycones, from a mutant strain of Micromonospora rosaria. | 1982 | J. Antibiot. | pmid:7076570 |
| Omura S et al. | Novel dimeric derivatives of leucomycins and tylosin, sixteen-membered macrolides. | 1982 | J. Med. Chem. | pmid:7040661 |
| Hopper RJ and Miller ML | Efficacy of swine erysipelas vaccine given simultaneously with medicated rations. | 1981 | Vet Med Small Anim Clin | pmid:6916559 |
| Shiel MJ et al. | Polyarthritis in a calf associated with a group 7 Mycoplasma infection. | 1982 | Aust. Vet. J. | pmid:6892005 |
| Sadakane N et al. | Hybrid biosynthesis of a new macrolide antibiotic by a daunomycin-producing microorganism. | 1983 | J. Antibiot. | pmid:6885644 |
| Lee BK et al. | Multistep bioconversion of 20-deoxo-20-dihydro-12,13-deepoxy-12,13-dehydrorosaranolide to 22-hydroxy-23-O-mycinosyl-20-deoxo-20-dihydro-12,13-deepoxy-rosaramicin. | 1983 | J. Antibiot. | pmid:6874596 |
| Omura S et al. | Valine as a precursor of n-butyrate unit in the biosynthesis of macrolide aglycone. | 1983 | J. Antibiot. | pmid:6874580 |
| Omura S et al. | Chimeramycins: new macrolide antibiotics produced by hybrid biosynthesis. | 1983 | J. Antibiot. | pmid:6860432 |
| Baltz RH et al. | Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin. | 1983 | J. Antibiot. | pmid:6833128 |
| Omura S et al. | Effect of ammonium ion, inorganic phosphate and amino acids on the biosynthesis of protylonolide, a precursor of tylosin aglycone. | 1984 | J. Antibiot. | pmid:6735923 |
| Stipkovits L et al. | A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas. | 1984 | Vet. Microbiol. | pmid:6730305 |
| Sakamoto M et al. | Deepoxidation of 16-membered epoxyenone macrolide antibiotics. III. In vitro and in vivo evaluation of deepoxidation products of carbomycin A, deltamycin A1, 4"-phenylacetyldeltamycin, angolamycin and rosamicin. | 1984 | J. Antibiot. | pmid:6706849 |
| Mutoh Y et al. | Deepoxidation of 16-membered epoxyenone macrolide antibiotics. II. Chemical deepoxidation by dissolving metal reduction. | 1984 | J. Antibiot. | pmid:6706848 |
| Omura S et al. | Ammonium ion suppresses the biosynthesis of tylosin aglycone by interference with valine catabolism in Streptomyces fradiae. | 1983 | J. Antibiot. | pmid:6662823 |
| Matsubara H et al. | Chemical modification of tylosin: synthesis of amino derivatives at C-20 position of tylosin and demycarosyltylosin. | 1983 | J. Antibiot. | pmid:6662813 |
| Omura S et al. | Ribosome-binding activities and antimicrobial activities of tylosin and its related compounds. | 1983 | J. Antibiot. | pmid:6662812 |
| Donev B et al. | [Toxicological studies of a combination of technical tylosin phosphate with bentonite (farmazin TB)]. | 1983 | Vet Med Nauki | pmid:6659350 |
| Thurman GD et al. | Diagnosis and successful treatment of subacute erysipelas in a captive dolphin. | 1983 | J S Afr Vet Assoc | pmid:6655661 |
| Hoffmann H et al. | [Antimicrobial activity in tissues of swine following subcutaneous administration of turimycin]. | 1983 | Arch Exp Veterinarmed | pmid:6651444 |
| Worseck M et al. | [Activity and minimal inhibitory concentration of turimycin against important pathogens in veterinary medicine]. | 1983 | Arch Exp Veterinarmed | pmid:6651443 |
| Dilov P et al. | [Toxicity, tolerance and blood concentrations of iron and tylosin with the use of preparation FV-82]. | 1983 | Vet Med Nauki | pmid:6623919 |
| Dafwang II et al. | Broiler chick growth response to antibiotics, 1981-1982. | 1984 | Poult. Sci. | pmid:6610176 |
| Sakamoto S et al. | Syntheses of 23-deoxy-23-N-ethyl-23-(2-fluoro-, 2,2-difluoro-, and 2,2,2-trifluoroethyl)amino derivatives of mycaminosyl tylonolide and 4'-deoxymycaminosyl tylonolide. | 1984 | J. Antibiot. | pmid:6526731 |
| Omura S et al. | Ammonium ions suppress the amino acid metabolism involved in the biosynthesis of protylonolide in a mutant of Streptomyces fradiae. | 1984 | J. Antibiot. | pmid:6511663 |
| Omura S et al. | Chemical modification of tylosin. Thioether derivatives of tylosin and demycarosyltylosin. | 1984 | J. Antibiot. | pmid:6501102 |
| Mackinnon JD et al. | Effect of tylosin on milk yield and dry matter intake of lactating dairy cows. | 1984 | Vet. Rec. | pmid:6495581 |
| Dilov P et al. | [Comparative studies on the resorption, anti-anemic action and growth effect of FV-82 and dextrofer-100 on pigs]. | 1984 | Vet Med Nauki | pmid:6474828 |
| Dotzlaf JE et al. | Incorporation of amino acid-derived carbon into tylactone by Streptomyces fradiae GS14. | 1984 | Antimicrob. Agents Chemother. | pmid:6424562 |
| Kietzmann M and Kreisner M | [Pharmacokinetics of chloramphenicol and tylosin in combined preparations. 2. Pharmacokinetic interaction between chloramphenicol and tylosin in calves and rats]. | 1983 | Zentralbl Veterinarmed A | pmid:6407242 |
| Kreisner M and Kietzmann M | [Pharmacokinetics of chloramphenicol, tylosin and prednisolone in combined preparations. 1. Thin-layer chromatographic determination of chloramphenicol, tylosin and prednisolone in serum]. | 1983 | Zentralbl Veterinarmed A | pmid:6407241 |
| Stipkovits L et al. | Efficacy of lasalocid sodium against mycoplasmas (preliminary communication). | 1984 | Acta Vet. Hung. | pmid:6242271 |
| Truscott RB and Ruhnke HL | The effect of antibiotics against bovine mycoplasmas and ureaplasmas. | 1984 | Can. J. Comp. Med. | pmid:6232992 |
| Wayner EA and Brooks CG | Induction of NKCF-like activity in mixed lymphocyte-tumor cell culture: direct involvement of mycoplasma infection of tumor cells. | 1984 | J. Immunol. | pmid:6230401 |
| Truscott RB | Factors associated with the determination of antibiotic activity in bovine semen. | 1983 | Can. J. Comp. Med. | pmid:6230144 |
| Jung HD | [Occupationally-induced contact eczema by tylosin (Tylan)]. | 1983 | Dermatol Monatsschr | pmid:6222923 |
| Simpson EJ et al. | A simple method for the removal of mycoplasma contamination from paramyxovirus stocks. | 1983 | J. Virol. Methods | pmid:6190834 |
| Shimi IR et al. | Staphcoccomycin, a new basic macrolide antibiotic. | 1979 | J. Antibiot. | pmid:541251 |
| Potter EL et al. | Effect of monensin and tylosin on average daily gain, feed efficiency and liver abscess incidence in feedlot cattle. | 1985 | J. Anim. Sci. | pmid:4077750 |
| Duthu GS | Interspecies correlation of the pharmacokinetics of erythromycin, oleandomycin, and tylosin. | 1985 | J Pharm Sci | pmid:4067847 |
| Baltz RH and Stonesifer J | Phenotypic changes associated with loss of expression of tylosin biosynthesis and resistance genes in Streptomyces fradiae. | 1985 | J. Antibiot. | pmid:4066505 |
| Moats WA | Chromatographic methods for determination of macrolide antibiotic residues in tissues and milk of food-producing animals. | 1985 Sep-Oct | J Assoc Off Anal Chem | pmid:4055648 |
| Tejedor F and Ballesta JP | Components of the macrolide binding site on the ribosome. | 1985 | J. Antimicrob. Chemother. | pmid:4055551 |
| Brumm MC and Peo ER | Effect of receiving diets containing alfalfa and certain feed additives on performance of feeder pigs transported long distances. | 1985 | J. Anim. Sci. | pmid:4030523 |