Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Danielson ND et al. Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. 1993 J Pharm Biomed Anal pmid:8504183
Lee SH and Lee KJ Aspartate aminotransferase and tylosin biosynthesis in Streptomyces fradiae. 1993 Appl. Environ. Microbiol. pmid:8481008
Jordan WH et al. A review of the toxicology of the antibiotic MICOTIL 300. 1993 Vet Hum Toxicol pmid:8470360
Roets E et al. Quantitative analysis of tylosin by column liquid chromatography. 1993 J. Chromatogr. pmid:8445000
Cester CC et al. Effect of stage of oestrous cycle on tylosin disposition in genital tract secretions of cows. 1993 Res. Vet. Sci. pmid:8434145
Binder S et al. [The effectiveness of tilmicosin in respiratory diseases of swine]. 1993 Berl. Munch. Tierarztl. Wochenschr. pmid:8431202
Morck DW et al. Prophylactic efficacy of tilmicosin for bovine respiratory tract disease. 1993 J. Am. Vet. Med. Assoc. pmid:8428833
Kageyama S et al. Synthesis of 3-deoxy-3,4-didehydro derivatives of 5-O-mycaminosyltylonolide, 5-O-(4-deoxymycaminosyl) tylonolide, and desmycosin. 1993 J. Antibiot. pmid:8407589
Tanner AC et al. A comparison of danofloxacin and tylosin in the control of induced Mycoplasma gallisepticum infection in broiler chicks. 1993 Apr-Jun Avian Dis. pmid:8395804
Migaki TT et al. Efficacy of danofloxacin and tylosin in the control of mycoplasmosis in chicks infected with tylosin-susceptible or tylosin-resistant field isolates of Mycoplasma gallisepticum. 1993 Apr-Jun Avian Dis. pmid:8395803
Cooper AC et al. In vitro activity of danofloxacin, tylosin and oxytetracycline against mycoplasmas of veterinary importance. 1993 Res. Vet. Sci. pmid:8393208
Meisel ML et al. Tylosin inhibits the steroidogenesis in mouse Leydig cells "in vitro". 1993 Life Sci. pmid:8390595
Jordan FT et al. A comparison of the efficacy of danofloxacin and tylosin in the control of Mycoplasma gallisepticum infection in broiler chicks. 1993 J. Vet. Pharmacol. Ther. pmid:8386777
Meisel ML et al. Effects of tylosin on the pituitary-gonadal axis in male rats. 1993 Apr-May Pharmacol. Toxicol. pmid:8372057
Huang SL et al. Purification and properties of NADPH-dependent tylosin reductase from Streptomyces fradiae. 1993 J. Biol. Chem. pmid:8360186
Westermarck E et al. Effect of treatment on the jejunal and colonic bacterial flora of dogs with exocrine pancreatic insufficiency. 1993 Pancreas pmid:8302792
Tanner AC et al. Adaptation of the Sensititre broth microdilution technique to antimicrobial susceptibility testing of Mycoplasma hyopneumoniae. 1993 Vet. Microbiol. pmid:8273275
Clary EM et al. Supplemental fat and ionophores in finishing diets: feedlot performance and ruminal digesta kinetics in steers. 1993 J. Anim. Sci. pmid:8270535
Stephens CP et al. In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Pasteurella haemolytica from cattle. 1993 Aust. Vet. J. pmid:8257321
Takhirov MT et al. [Determination of tylosin in the water supply using a chromatographic method]. 1993 Gig Sanit pmid:8244081