Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Ueda Y et al. Effect of terdecamycin on experimentally induced Mycoplasma hyopneumoniae-infection in pigs. 1994 Zentralblatt Veterinarmedizin Reihe B pmid:7839749
Parker RM and Patel RK Determination of tilmicosin in ovine milk using high-performance liquid chromatography. 1994 Analyst pmid:7879857
Delepine B et al. Identification of tylosin in bovine muscle at the maximum residue limit level by liquid chromatography-mass spectrometry, using a particle beam interface. 1994 Analyst pmid:7879883
Kirchgessner M et al. [The effect of avilamycin and tylosin on the apparent digestibility of iron, zinc, copper, manganese and selenium in the beginning and ending performance of swine]. 1994 Arch Tierernahr pmid:7778980
Scott DW et al. Efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1994 Can. Vet. J. pmid:7994702
Narandja A et al. Structure-activity relationship among polyhydro derivatives of tylosin. 1994 J. Antibiot. pmid:8040056
Duff GC et al. Effects of lasalocid and monensin plus tylosin on serum metabolic hormones and clinical chemistry profiles of beef steers fed a 90% concentrate diet. 1994 J. Anim. Sci. pmid:8014140
Kounenis G et al. Comparative study of erythromycin, troleandomycin and tylosin on the rabbit intestine. 1994 Fundam Clin Pharmacol pmid:8020874
Kageyama S and Tsuchiya T Synthesis of 2-C-methyl derivatives of 3,4'-dideoxymycaminosyltylonolide, a novel type of 16-membered macrolide antibiotic. 1994 J. Antibiot. pmid:7928687
Kelemen GH et al. Transcriptional attenuation control of the tylosin-resistance gene tlrA in Streptomyces fradiae. 1994 Mol. Microbiol. pmid:7534372
Lee SH and Lee KJ Kinetics of the repression of tylosin biosynthesis by ammonium ion in Streptomyces fradiae. 1994 J. Biotechnol. pmid:7764561
Danese P et al. Occupational contact dermatitis from tylosin. 1994 Contact Derm. pmid:8187499
Shryock TR et al. Effect of bentonite incorporated in a feed ration with tilmicosin in the prevention of induced Mycoplasma gallisepticum airsacculitis in broiler chickens. 1994 Jul-Sep Avian Dis. pmid:7832702
Chan W et al. Determination of tylosin and tilmicosin residues in animal tissues by reversed-phase liquid chromatography. 1994 Mar-Apr J AOAC Int pmid:8199468
Nguyen LT et al. The tylosin producer, Streptomyces fradiae, contains a second valine dehydrogenase. 1995 Microbiology (Reading, Engl.) pmid:7773408
Paesen J et al. Isolation of decomposition products of tylosin using liquid chromatography. 1995 J Chromatogr A pmid:7757214
Shryock TR et al. Proposed quality control guidelines for antimicrobial susceptibility tests using tilmicosin. 1995 J. Clin. Microbiol. pmid:7714188
Bobillot S et al. Chemical modification of tylosin. 1995 J. Antibiot. pmid:7649866
Creemer LC et al. Synthesis, antimicrobial activity and in vivo fluorine NMR of a hexafluorinated derivative of tilmicosin. 1995 J. Antibiot. pmid:7649867
Narandja A et al. 10,11,12,13-Tetrahydro derivatives of tylosin. II. Synthesis, antibacterial activity and tissue of 4'-deoxy-10,11,12,13-tetrahydrodesmycosin. 1995 J. Antibiot. pmid:7730160
Paesen J et al. Study of the stability of tylosin A in aqueous solutions. 1995 J Pharm Biomed Anal pmid:8573642
Ziv G et al. Disposition kinetics of tylosin tartrate administered intravenously and intramuscularly to normal and water-deprived camels. 1995 J. Vet. Pharmacol. Ther. pmid:8583543
Ziv G et al. Tilmicosin antibacterial activity and pharmacokinetics in cows. 1995 J. Vet. Pharmacol. Ther. pmid:8587151
Brown SA et al. Characterization of plasma and lung concentrations after ceftiofur sodium and tilmicosin phosphate administered subcutaneously to mice. 1995 J. Vet. Pharmacol. Ther. pmid:8587160
Blackall PJ et al. In-vitro antibacterial properties of tilmicosin against Australian isolates of Pasteurella multocida and Actinobacillus pleuropneumoniae from pigs. 1995 Aust. Vet. J. pmid:8787526
Tuomi ML and Räsänen L Contact allergy to tylosin and cobalt in a pig-farmer. 1995 Contact Derm. pmid:8654098
Lee SH and Lee KJ Threonine dehydratases in different strains of Streptomyces fradiae. 1995 J. Biotechnol. pmid:8562022
Kirchgessner M et al. [Effect of avilamycin and tylosin on the metabolizable energy in growing and finishing pigs]. 1995 Arch Tierernahr pmid:8526732
Kiehl DE and Kennington AS Analysis of tilmicosin in swine liver extracts by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry. 1995 Rapid Commun. Mass Spectrom. pmid:8527821
Harvey RB et al. Influence of the antibiotics lincomycin and tylosin on aflatoxicosis when added to aflatoxin-contaminated diets of growing swine. 1995 J. Vet. Diagn. Invest. pmid:7578454
Stock RA et al. Effect of monensin and monensin and tylosin combination on feed intake variation of feedlot steers. 1995 J. Anim. Sci. pmid:7601752
Zuzulova M et al. In vitro activity of tylosin and its derivatives against Ureaplasma urealyticum. 1995 Arzneimittelforschung pmid:8929244
Galyean ML et al. Effects of arrival medication with tilmicosin phosphate on health and performance of newly received beef cattle. 1995 J. Anim. Sci. pmid:7665351
Scott PR Efficacy of strategic tilmicosin injection during an outbreak of respiratory disease in housed beef calves. 1995 Sep-Oct Br. Vet. J. pmid:8556318
Moore GM et al. Clinical field trials with tilmicosin phosphate in feed for the control of naturally acquired pneumonia caused by Actinobacillus pleuropneumoniae and Pasteurella multocida in swine. 1996 Am. J. Vet. Res. pmid:8633813
Day FG The value of tilmicosin in production medicine. 1996 J. Am. Vet. Med. Assoc. pmid:8617615
Solenberg PJ et al. Transposition mutagenesis in Streptomyces fradiae: identification of a neutral site for the stable insertion of DNA by transposon exchange. 1996 Gene pmid:8626067
Arisawa A et al. Direct fermentative production of acyltylosins by genetically-engineered strains of Streptomyces fradiae. 1996 J. Antibiot. pmid:8641997
Main BW et al. Cardiovascular effects of the macrolide antibiotic tilmicosin, administered alone and in combination with propranolol or dobutamine, in conscious unrestrained dogs. 1996 J. Vet. Pharmacol. Ther. pmid:8803881
Peng CY et al. Laboratory and field studies on the effects of the antibiotic tylosin on honey bee Apis mellifera L. (Hymenoptera: Apidae) development and prevention of American foulbrood disease. 1996 J. Invertebr. Pathol. pmid:8812572
Scott PR et al. Use of tilmicosin in a severe outbreak of respiratory disease in weaned beef calves. 1996 Aust. Vet. J. pmid:8660201
Wittum TE et al. Haptoglobin response to clinical respiratory tract disease in feedlot cattle. 1996 Am. J. Vet. Res. pmid:8723875
Musser J et al. Comparison of tilmicosin with long-acting oxytetracycline for treatment of respiratory tract disease in calves. 1996 J. Am. Vet. Med. Assoc. pmid:8682696
Fish SA and Cundliffe E Structure-activity studies of tylosin-related macrolides. 1996 J. Antibiot. pmid:8968399
Katoh T et al. The fractional inhibitory concentration index of antimicrobial agents for bacteria and Mycoplasma isolated from the nasal swabs of cattle with respiratory diseases. 1996 J. Vet. Med. Sci. pmid:8877979
Katoh T et al. Effect of a combination of antimicrobial agents for the treatment of respiratory disease in cattle. 1996 J. Vet. Med. Sci. pmid:8877980
McKay SG et al. Use of tilmicosin for treatment of pasteurellosis in rabbits. 1996 Am. J. Vet. Res. pmid:8836371
Kobayashi H et al. Macrolide susceptibility of Mycoplasma hyorhinis isolated from piglets. 1996 Antimicrob. Agents Chemother. pmid:8849222
Gandecha AR and Cundliffe E Molecular analysis of tlrD, an MLS resistance determinant from the tylosin producer, Streptomyces fradiae. 1996 Gene pmid:8973363
Kuhstoss S et al. Production of a novel polyketide through the construction of a hybrid polyketide synthase. 1996 Gene pmid:8996112