| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Bacterial Infections | D001424 | 21 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Cattle Diseases | D002418 | 24 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Facial Dermatoses | D005148 | 7 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Asthma | D001249 | 52 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
Tylosin
Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Tylosin?
Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (6)
- Appl. Environ. Microbiol. (2)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (6)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Tylosin
PubChem Associated disorders and diseases
What pathways are associated with Tylosin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Tylosin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Tylosin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Tylosin?
There are no associated biomedical information in the current reference collection.
What genes are associated with Tylosin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (9)
- Microbiology (Reading, Engl.) (3)
- Proc. Natl. Acad. Sci. U.S.A. (2)
- Others (13)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Tylosin?
Knock-out
Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with Tylosin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Giordano R et al. | Effect of a high dose of three antibiotics on the reproduction of a parthenogenetic strain of Folsomia candida (Isotomidae: Collembola). | 2010 | Environ. Entomol. | pmid:22127168 |
| Aust MO et al. | Distribution of sulfamethazine, chlortetracycline and tylosin in manure and soil of Canadian feedlots after subtherapeutic use in cattle. | 2008 | Environ. Pollut. | pmid:18440678 |
| Kay P et al. | A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data. | 2005 | Environ. Pollut. | pmid:15589660 |
| Brain RA et al. | Aquatic microcosm assessment of the effects of tylosin on Lemna gibba and Myriophyllum spicatum. | 2005 | Environ. Pollut. | pmid:15519715 |
| Zhang YJ et al. | Temporal succession of soil antibiotic resistance genes following application of swine, cattle and poultry manures spiked with or without antibiotics. | 2017 | Environ. Pollut. | pmid:28964602 |
| Kline A and Pinckney JL | Size-selective toxicity effects of the antimicrobial tylosin on estuarine phytoplankton communities. | 2016 | Environ. Pollut. | pmid:27376985 |
| Pei Z et al. | Effects of copper and aluminum on the adsorption of sulfathiazole and tylosin on peat and soil. | 2014 | Environ. Pollut. | pmid:24201036 |
| Liu F et al. | Effects of six selected antibiotics on plant growth and soil microbial and enzymatic activities. | 2009 | Environ. Pollut. | pmid:19157661 |
| Teeter JS and Meyerhoff RD | Aerobic degradation of tylosin in cattle, chicken, and swine excreta. | 2003 | Environ. Res. | pmid:12865047 |
| Hu D et al. | Identification of tylosin photoreaction products and comparison of ELISA and HPLC methods for their detection in water. | 2008 | Environ. Sci. Technol. | pmid:18497154 |
| Demoling LA and Bååth E | No long-term persistence of bacterial pollution-induced community tolerance in tylosin-polluted soil. | 2008 | Environ. Sci. Technol. | pmid:18853809 |
| Sassman SA et al. | Sorption of tylosin A, D, and A-aldol and degradation of tylosin A in soils. | 2007 | Environ. Toxicol. Chem. | pmid:17702335 |
| Loftin KA et al. | Inhibition of microbial metabolism in anaerobic lagoons by selected sulfonamides, tetracyclines, lincomycin, and tylosin tartrate. | 2005 | Environ. Toxicol. Chem. | pmid:15839550 |
| Halling-Sørensen B et al. | Dissipation and effects of chlortetracycline and tylosin in two agricultural soils: a field-scale study in southern Denmark. | 2005 | Environ. Toxicol. Chem. | pmid:15839553 |
| Carlson JC and Mabury SA | Dissipation kinetics and mobility of chlortetracycline, tylosin, and monensin in an agricultural soil in Northumberland County, Ontario, Canada. | 2006 | Environ. Toxicol. Chem. | pmid:16494218 |
| ter Laak TL et al. | The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. | 2006 | Environ. Toxicol. Chem. | pmid:16629129 |
| ter Laak TL et al. | Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. | 2006 | Environ. Toxicol. Chem. | pmid:16629132 |
| Kay P et al. | Fate of veterinary antibiotics in a macroporous tile drained clay soil. | 2004 | Environ. Toxicol. Chem. | pmid:15180364 |
| Hu D and Coats JR | Aerobic degradation and photolysis of tylosin in water and soil. | 2007 | Environ. Toxicol. Chem. | pmid:17521133 |
| Iveković D et al. | Electrochemical reduction of desmycosin, structure investigation and antibacterial evaluation of the resulting products. | 2003 | Eur J Pharm Sci | pmid:12694884 |
| Shakeri-Nejad K and Stahlmann R | Drug interactions during therapy with three major groups of antimicrobial agents. | 2006 | Expert Opin Pharmacother | pmid:16556082 |
| Residues of some veterinary drugs in animals and foods. Monographs prepared by the Forty-Seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives. Rome, 4-13 June 1996. | 1997 | FAO Food Nutr Pap | pmid:9253593 | |
| Residues of some veterinary drugs in animals and foods. Monographs prepared by the thirty-eighth meeting of the Joint FAO/WHO Expert Committee on Food Additives. | 1991 | FAO Food Nutr Pap | pmid:1687815 | |
| Moretto A et al. | Slow release of two antibiotics of veterinary interest from PVA hydrogels. | 2004 | Farmaco | pmid:14751309 |
| Holman DB and Chénier MR | Temporal changes and the effect of subtherapeutic concentrations of antibiotics in the gut microbiota of swine. | 2014 | FEMS Microbiol. Ecol. | pmid:25187398 |
| Cleary DW et al. | Long-term antibiotic exposure in soil is associated with changes in microbial community structure and prevalence of class 1 integrons. | 2016 | FEMS Microbiol. Ecol. | pmid:27495240 |
| Holman DB and Chénier MR | Impact of subtherapeutic administration of tylosin and chlortetracycline on antimicrobial resistance in farrow-to-finish swine. | 2013 | FEMS Microbiol. Ecol. | pmid:23397987 |
| Onan LJ and LaPara TM | Tylosin-resistant bacteria cultivated from agricultural soil. | 2003 | FEMS Microbiol. Lett. | pmid:12644222 |
| Taniguchi K et al. | The role of histidine residues conserved in the putative ATP-binding region of macrolide 2'-phosphotransferase II. | 2004 | FEMS Microbiol. Lett. | pmid:15033229 |
| Fouces R et al. | Conjugation and transformation of Streptomyces species by tylosin resistance. | 2000 | FEMS Microbiol. Lett. | pmid:10802191 |
| Wu CM et al. | Induction of macrolide resistance in Mycoplasma gallisepticum in vitro and its resistance-related mutations within domain V of 23S rRNA. | 2005 | FEMS Microbiol. Lett. | pmid:15936901 |
| Rezanka T et al. | Isobutyrate as a precursor of n-butyrate in the biosynthesis of tylosine and fatty acids. | 1991 | FEMS Microbiol. Lett. | pmid:1769552 |
| Fujiwara T and Takenaka S | Bioconversion of 19-deformyl-5-O-desosaminyl tylonolide to 19-deformyl-4'-deoxydesmycosin (TMC-016). | 1990 | FEMS Microbiol. Lett. | pmid:2379808 |
| Karlsson M et al. | Genetic basis of macrolide and lincosamide resistance in Brachyspira (Serpulina) hyodysenteriae. | 1999 | FEMS Microbiol. Lett. | pmid:10188254 |
| Higgins HC and McEvoy JD | Accelerated solvent extraction of animal feedingstuffs for microbial growth inhibition screening for the presence of antimicrobial feed additives. | 2002 | Food Addit Contam | pmid:12396393 |
| Montesissa C et al. | Tylosin depletion in edible tissues of turkeys. | 1999 | Food Addit Contam | pmid:10755131 |
| Koenen-Dierick K and De Beer JO | Optimization of an antibiotic residue screening test, based on inhibition of Bacillus subtilis BGA, with experimental design. | 1998 | Food Addit Contam | pmid:9829036 |
| Vincent U et al. | Validation of an analytical method for the determination of spiramycin, virginiamycin and tylosin in feeding-stuffs by thin-layer chromatography and bio-autography. | 2007 | Food Addit Contam | pmid:17454108 |
| Patyra E et al. | Development and validation of an LC-MS/MS method for the quantification of tiamulin, trimethoprim, tylosin, sulfadiazine and sulfamethazine in medicated feed. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:29324179 |
| Cornejo J et al. | Depletion of tylosin residues in feathers, muscle and liver from broiler chickens after completion of antimicrobial therapy. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:29111882 |
| De Baere S et al. | In vitro model to assess the adsorption of oral veterinary drugs to mycotoxin binders in a feed- and aflatoxin B1-containing buffered matrix. | 2018 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:30016205 |
| Le T et al. | A quantum dot-based immunoassay for screening of tylosin and tilmicosin in edible animal tissues. | 2015 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:25822697 |
| Stead SL et al. | Development and validation of a potentiometric biosensor assay for tylosin with demonstrated applicability for the detection of two other antimicrobial growth-promoter compounds in feedstuffs. | 2011 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:21574083 |
| Gaudin V et al. | Validation of two ELISA kits for the screening of tylosin and streptomycin in honey according to the European decision 2002/657/EC. | 2013 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:23013044 |
| Pol-Hofstad I et al. | Collaborative study of a microbiological screening method (three-plate) for the banned antimicrobial growth promotors tylosin, virginiamycin, spiramycin, zinc bacitracin and avoparcin in animal feed. | 2008 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess | pmid:19680856 |
| Baggio A et al. | Residues of antibacterial drugs in honey from the Italian market. | 2009 | Food Addit Contam Part B Surveill | pmid:24784967 |
| Molognoni L et al. | Development of a LC-MS/MS method for the simultaneous determination of sorbic acid, natamycin and tylosin in Dulce de leche. | 2016 | Food Chem | pmid:27283692 |
| Hume ME and Donskey CJ | Effect of Vancomycin, Tylosin, and Chlortetracycline on Vancomycin-Resistant Enterococcus faecium Colonization of Broiler Chickens During Grow-Out. | 2017 | Foodborne Pathog. Dis. | pmid:28128649 |
| Amachawadi RG et al. | Effects of In-Feed Copper, Chlortetracycline, and Tylosin on the Prevalence of Transferable Copper Resistance Gene, tcrB, Among Fecal Enterococci of Weaned Piglets. | 2015 | Foodborne Pathog. Dis. | pmid:26258261 |
| Apley MD et al. | Use estimates of in-feed antimicrobials in swine production in the United States. | 2012 | Foodborne Pathog. Dis. | pmid:22324295 |