Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Peltier E et al. Zinc-induced antibiotic resistance in activated sludge bioreactors. 2010 Water Res. pmid:20537675
Granja R et al. Determination of erythromycin and tylosin residues in honey by LC/MS/MS. 2009 May-Jun J AOAC Int pmid:19610392
Sharma R et al. Selected antimicrobial resistance during composting of manure from cattle administered sub-therapeutic antimicrobials. 2009 Mar-Apr J. Environ. Qual. pmid:19202027
Smith GW et al. Elimination kinetics of tilmicosin following intramammary administration in lactating dairy cattle. 2009 J. Am. Vet. Med. Assoc. pmid:19210246
Kouvela EC et al. Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity. 2009 Antimicrob. Agents Chemother. pmid:19164155
Baggio A et al. Residues of antibacterial drugs in honey from the Italian market. 2009 Food Addit Contam Part B Surveill pmid:24784967
Chemier JA et al. Trends in microbial synthesis of natural products and biofuels. 2009 Adv. Enzymol. Relat. Areas Mol. Biol. pmid:18990830
Montgomery JL et al. Effects of dietary zilpaterol hydrochloride on feedlot performance and carcass characteristics of beef steers fed with and without monensin and tylosin. 2009 J. Anim. Sci. pmid:18997069
Boles JA et al. Growth implants reduced tenderness of steaks from steers and heifers with different genetic potentials for growth and marbling. 2009 J. Anim. Sci. pmid:18791138
Han C et al. Hydrogenated castor oil nanoparticles as carriers for the subcutaneous administration of tilmicosin: in vitro and in vivo studies. 2009 J. Vet. Pharmacol. Ther. pmid:19290940
Engi H [Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments]. 2009 Orv Hetil pmid:19293063
Hoese A et al. Chlortetracycline and tylosin runoff from soils treated with antimicrobial containing manure. 2009 J Environ Sci Health B pmid:19365753
Meyer NF et al. Effect of essential oils, tylosin, and monensin on finishing steer performance, carcass characteristics, liver abscesses, ruminal fermentation, and digestibility. 2009 J. Anim. Sci. pmid:19359504
Christodoulopoulos G Adverse outcome of using tilmicosin in a lamb with multiple ventricular septal defects. 2009 Can. Vet. J. pmid:19337615
Khaliq S et al. Production of tylosin in solid-state fermentation by Streptomyces fradiae NRRL-2702 and its gamma-irradiated mutant (gamma-1). 2009 Lett. Appl. Microbiol. pmid:19780953
Hu D and Coats JR Laboratory evaluation of mobility and sorption for the veterinary antibiotic, tylosin, in agricultural soils. 2009 J Environ Monit pmid:19724833
Khalifeh MS et al. Assessment of humoral and cellular-mediated immune response in chickens treated with tilmicosin, florfenicol, or enrofloxacin at the time of Newcastle disease vaccination. 2009 Poult. Sci. pmid:19762865
Guedes RM et al. Use of tylvalosin-medicated feed to control porcine proliferative enteropathy. 2009 Vet. Rec. pmid:19767637
Fitzgerald J Administration of micotil. 2009 Vet. Rec. pmid:19767643
Stone JJ et al. Effect of antimicrobial compounds tylosin and chlortetracycline during batch anaerobic swine manure digestion. 2009 Water Res. pmid:19695662
Atef M et al. Effect of albendazole administration on pharmacokinetic aspects of tylosin in lactating goats. 2009 Drug Metab Lett pmid:19702546
Hilton GG et al. Effects of feeding zilpaterol hydrochloride with and without monensin and tylosin on carcass cutability and meat palatability of beef steers. 2009 J. Anim. Sci. pmid:19028853
Byrne-Bailey KG et al. Prevalence of sulfonamide resistance genes in bacterial isolates from manured agricultural soils and pig slurry in the United Kingdom. 2009 Antimicrob. Agents Chemother. pmid:19064898
Petropoulos AD et al. Time-resolved binding of azithromycin to Escherichia coli ribosomes. 2009 J. Mol. Biol. pmid:19071138
Blackwell PA et al. Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. 2009 Chemosphere pmid:19128817
Chénier MR and Juteau P Fate of chlortetracycline- and tylosin-resistant bacteria in an aerobic thermophilic sequencing batch reactor treating swine waste. 2009 Microb. Ecol. pmid:19125305
Liu F et al. Effects of six selected antibiotics on plant growth and soil microbial and enzymatic activities. 2009 Environ. Pollut. pmid:19157661
Bodoor K et al. Design and implementation of an ribonucleic acid (RNA) directed fragment library. 2009 J. Med. Chem. pmid:19445516
Hunter RP et al. Letter to the editor. 2009 Br. Poult. Sci. pmid:19904632
Suchodolski JS et al. The effect of the macrolide antibiotic tylosin on microbial diversity in the canine small intestine as demonstrated by massive parallel 16S rRNA gene sequencing. 2009 BMC Microbiol. pmid:19799792
Warner K et al. Control of Ornithobacterium rhinotracheale in poultry. 2009 Vet. Rec. pmid:19946131
Hao H et al. 23S rRNA mutation A2074C conferring high-level macrolide resistance and fitness cost in Campylobacter jejuni. 2009 Microb. Drug Resist. pmid:19857128
Khaliq S et al. Change in colony morphology and kinetics of tylosin production after UV and gamma irradiation mutagenesis of Streptomyces fradiae NRRL-2702. 2009 Microbiol. Res. pmid:17475458
Smith LK and Mankin AS Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. 2008 Antimicrob. Agents Chemother. pmid:18299405
Aust MO et al. Distribution of sulfamethazine, chlortetracycline and tylosin in manure and soil of Canadian feedlots after subtherapeutic use in cattle. 2008 Environ. Pollut. pmid:18440678
Douthwaite S et al. Interaction of the tylosin-resistance methyltransferase RlmA II at its rRNA target differs from the orthologue RlmA I. 2008 J. Mol. Biol. pmid:18406425
Reuter RR et al. Effects of dietary energy source and level and injection of tilmicosin phosphate on immune function in lipopolysaccharide-challenged beef steers. 2008 J. Anim. Sci. pmid:18407986
Mir PS et al. Effects of dietary sunflower seeds and tylosin phosphate on production variables, carcass characteristics, fatty acid composition, and liver abscess incidence in crossbred steers. 2008 J. Anim. Sci. pmid:18567724
Nickell JS et al. Comparison of short-term health and performance effects related to prophylactic administration of tulathromycin versus tilmicosin in long-hauled, highly stressed beef stocker calves. 2008 Vet. Ther. pmid:18597253
Chen J et al. Technical note: Occurrence in fecal microbiota of genes conferring resistance to both macrolide-lincosamide-streptogramin B and tetracyclines concomitant with feeding of beef cattle with tylosin. 2008 J. Anim. Sci. pmid:18469042
Depenbusch BE et al. Efficacy of monensin and tylosin in finishing diets based on steam-flaked corn with and without corn wet distillers grains with solubles. 2008 J. Anim. Sci. pmid:18469059
Shimada T et al. Modelling the effect of the antimicrobial tylosin on the performance of an anaerobic sequencing batch reactor. 2008 Water Sci. Technol. pmid:18547919
Gallina G et al. Acute toxicity evaluation of four antibacterials with Daphnia magna. 2008 Vet. Res. Commun. pmid:18688742
Stoev G and Nazarov V Identification of the related substances of tilmicosin by liquid chromatography/ion trap mass spectrometry. 2008 Rapid Commun. Mass Spectrom. pmid:18491285
Achard A et al. Emergence of macrolide resistance gene mph(B) in Streptococcus uberis and cooperative effects with rdmC-like gene. 2008 Antimicrob. Agents Chemother. pmid:18519724
Crespo R and McMillan R Facial cellulitis induced in chickens by Mycoplasma gallisepticum bacterin and its treatment. 2008 Avian Dis. pmid:19166067
Nathues H and grosse Beilage E Diagnosis of Lawsonia intracellularis infection in pigs after vaccination or antimicrobial treatment. 2008 DTW. Dtsch. Tierarztl. Wochenschr. pmid:19024547
Oakes J and Seifert S American association of poison control centers database characterization of human tilmicosin exposures, 2001-2005. 2008 J Med Toxicol pmid:19031373
Catry B et al. Efficacy of metaphylactic florfenicol therapy during natural outbreaks of bovine respiratory disease. 2008 J. Vet. Pharmacol. Ther. pmid:19000268
Fricke JA et al. Pharmacokinetics and tissue depletion of tilmicosin in turkeys. 2008 J. Vet. Pharmacol. Ther. pmid:19000285