Tylosin

Tylosin is a lipid of Polyketides (PK) class. Tylosin is associated with abnormalities such as Mastitis, Bovine, Infection, Bacterial Infections, Arthritis and Ileitis. The involved functions are known as Anabolism, acireductone dioxygenase [iron(II)-requiring] activity, Protein Biosynthesis, Mastitis and Methylation. Tylosin often locates in Ribosomes, Cell Wall, 50S ribosomal subunit, Ribosome Subunits, Large and Ribosome Subunits. The associated genes with Tylosin are Gene Clusters, Genome, resistance genes, Homologous Gene and HM13 gene. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Tylosin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tylosin?

Tylosin is suspected in Porcine ulcerative spirochetosis, Infection, Liver Abscess, Respiration Disorders, Intestinal Diseases, Mastitis, Bovine and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tylosin

PubChem Associated disorders and diseases

What pathways are associated with Tylosin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tylosin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Tylosin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Tylosin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Tylosin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tylosin?

Knock-out

Knock-out are used in the study 'A second tylosin resistance determinant, Erm B, in Arcanobacterium pyogenes.' (Jost BH et al., 2004).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tylosin

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Authors Title Published Journal PubMed Link
Scott DW et al. Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1996 Can. Vet. J. pmid:8896878
Houglum JE and Tasler MK Liquid chromatographic assay of tylosin in animal feeds. 1996 Mar-Apr J AOAC Int pmid:8920123
Delépine B et al. Multiresidue method for confirmation of macrolide antibiotics in bovine muscle by liquid chromatography/mass spectrometry. 1996 Mar-Apr J AOAC Int pmid:8920126
Zuzulova M et al. In vitro activity of tylosin and its derivatives against Ureaplasma urealyticum. 1995 Arzneimittelforschung pmid:8929244
Markakis PK Microbiological method for determining macrolides in animal feeds in the presence of other drugs by thin-layer chromatography detection. 1996 Nov-Dec J AOAC Int pmid:8946704
Kobayashi H et al. In vitro susceptibility of Mycoplasma hyosynoviae and M. hyorhinis to antimicrobial agents. 1996 J. Vet. Med. Sci. pmid:8959659
Fish SA and Cundliffe E Structure-activity studies of tylosin-related macrolides. 1996 J. Antibiot. pmid:8968399
Gandecha AR and Cundliffe E Molecular analysis of tlrD, an MLS resistance determinant from the tylosin producer, Streptomyces fradiae. 1996 Gene pmid:8973363
Kuhstoss S et al. Production of a novel polyketide through the construction of a hybrid polyketide synthase. 1996 Gene pmid:8996112
McOrist S et al. Oral administration of tylosin phosphate for treatment and prevention of proliferative enteropathy in pigs. 1997 Am. J. Vet. Res. pmid:9028475