erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Trench Fever D014205 1 associated lipids
Splenic Infarction D013159 1 associated lipids
Thyroid Crisis D013958 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Papillon-Lefevre Disease D010214 1 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Megacolon D008531 1 associated lipids
Spider Bites D001098 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Chen C et al. Blocking the flow of propionate into TCA cycle through a mutB knockout leads to a significant increase of erythromycin production by an industrial strain of Saccharopolyspora erythraea. 2017 Bioprocess Biosyst Eng pmid:27709326
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Liu J et al. Interaction of erythromycin and ketoconazole on the neurological, biochemical and behavioral responses in crucian carp. 2017 Environ. Toxicol. Pharmacol. pmid:28802958
Lee JK et al. Changes in the Serotype Distribution among Antibiotic Resistant Carriage Streptococcus pneumoniae Isolates in Children after the Introduction of the Extended-Valency Pneumococcal Conjugate Vaccine. 2017 J. Korean Med. Sci. pmid:28776337
Jakkidi M et al. An illusion of septic shock: acute generalised exanthematous pustulosis with multiorgan dysfunction. 2017 BMJ Case Rep pmid:28768672
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Lamari F et al. Assessment of the correlation among antibiotic resistance, adherence to abiotic and biotic surfaces, invasion and cytotoxicity of Pseudomonas aeruginosa isolated from diseased gilthead sea bream. 2017 Colloids Surf B Biointerfaces pmid:28697438
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Wang D et al. An analogous wood barrel theory to explain the occurrence of hormesis: A case study of sulfonamides and erythromycin on Escherichia coli growth. 2017 PLoS ONE pmid:28715457
Jia L et al. Synthesis and antibacterial evaluation of novel 11-O-carbamoyl clarithromycin ketolides. 2017 Bioorg. Med. Chem. Lett. pmid:28711353
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Hodge S et al. Nonantibiotic macrolides restore airway macrophage phagocytic function with potential anti-inflammatory effects in chronic lung diseases. 2017 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:28258107
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Waites KB et al. In Vitro Activities of Lefamulin and Other Antimicrobial Agents against Macrolide-Susceptible and Macrolide-Resistant Mycoplasma pneumoniae from the United States, Europe, and China. 2017 Antimicrob. Agents Chemother. pmid:27855075
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Zhang W et al. Isolation and characterization of a high-efficiency erythromycin A-degrading Ochrobactrum sp. strain. 2017 Mar. Pollut. Bull. pmid:27863881
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Liu J et al. Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea. 2017 Metab. Eng. pmid:27794466
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Zhou X et al. Erythromycin attenuates metalloprotease/anti-metalloprotease imbalance in cigarette smoke-induced emphysema in rats via the mitogen-activated protein kinase/nuclear factor-κB activation pathway. 2017 Mol Med Rep pmid:28358431
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Ksia S et al. Molecular Characteristics of Erythromycin-Resistant Streptococcus pyogenes Strains Isolated from Children Patients in Tunis, Tunisia. 2017 Microb. Drug Resist. pmid:27991848
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