erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Grier M et al. | Do antibiotics improve neonatal outcomes in preterm premature rupture of membranes (PPROM)? | 2001 | J Fam Pract | pmid:11485716 |
Emoto C et al. | Cooperativity of alpha-naphthoflavone in cytochrome P450 3A-dependent drug oxidation activities in hepatic and intestinal microsomes from mouse and human. | 2001 | Xenobiotica | pmid:11491388 |
Welling PG et al. | Prediction of drug dosage in patients with renal failure using data derived from normal subjects. | 1975 | Clin. Pharmacol. Ther. | pmid:1149361 |
Farpour B and McClellan KA | Diagnosis and management of chronic blepharokeratoconjunctivitis in children. | 2001 Jul-Aug | J Pediatr Ophthalmol Strabismus | pmid:11495307 |
Eagle DA et al. | Gastroparesis following bone marrow transplantation. | 2001 | Bone Marrow Transplant. | pmid:11498745 |
Tyteca D et al. | Azithromycin, a lysosomotropic antibiotic, impairs fluid-phase pinocytosis in cultured fibroblasts. | 2001 | Eur. J. Cell Biol. | pmid:11499789 |
Morosini MI et al. | In vitro activity of telithromycin against Spanish Streptococcus pneumoniae isolates with characterized macrolide resistance mechanisms. | 2001 | Antimicrob. Agents Chemother. | pmid:11502509 |
Mitten MJ et al. | Efficacies of ABT-773, a new ketolide, against experimental bacterial infections. | 2001 | Antimicrob. Agents Chemother. | pmid:11502533 |
Kenny GE and Cartwright FD | Susceptibilities of Mycoplasma hominis, M. pneumoniae, and Ureaplasma urealyticum to GAR-936, dalfopristin, dirithromycin, evernimicin, gatifloxacin, linezolid, moxifloxacin, quinupristin-dalfopristin, and telithromycin compared to their susceptibilities to reference macrolides, tetracyclines, and quinolones. | 2001 | Antimicrob. Agents Chemother. | pmid:11502536 |
Mavroidi A et al. | Multidrug-resistant strains of Neisseria gonorrhoeae in Greece. | 2001 | Antimicrob. Agents Chemother. | pmid:11502546 |
Byarugaba W et al. | Toxicity of antibiotics on cultured human skin fibroblasts. | 1975 | Humangenetik | pmid:1150286 |
de Mey C et al. | Erythromycin increases plasma concentrations of alpha-dihydroergocryptine in humans. | 2001 | Clin. Pharmacol. Ther. | pmid:11503008 |
Choosing a macrolide: drug interactions must be taken into account. | 1999 | Prescrire Int | pmid:11503822 | |
Erythromycin-induced pyloric stenosis in infants. | 2001 | Prescrire Int | pmid:11503852 | |
Flickinger MC and Perlman D | Microbial degradation of erythromycins A and B. | 1975 | J. Antibiot. | pmid:1150530 |
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Talley NJ et al. | Effects of a motilin receptor agonist (ABT-229) on upper gastrointestinal symptoms in type 1 diabetes mellitus: a randomised, double blind, placebo controlled trial. | 2001 | Gut | pmid:11511562 |
Shengxi C et al. | 3-Keto-9-O-substituted oxime derivatives of 6-O-methyl erythromycin A synthesis and in vitro activity. | 2001 | J. Antibiot. | pmid:11513040 |
Bernabéu JA et al. | Procedure to evaluate the stability during processing and storage of a medicated premix and medicated farm feed: erythromycin thiocyanate. | 2001 | J. Agric. Food Chem. | pmid:11513652 |
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Katagiri K et al. | Staphylococcal footpad infection in mice. | 1975 | Jpn. J. Microbiol. | pmid:1152301 |
MartÃnez MA et al. | Occurrence and antimicrobial susceptibility of Ureaplasma parvum (Ureaplasma urealyticum biovar 1) and Ureaplasma urealyticum (Ureaplasma urealyticum biovar 2) from patients with adverse pregnancy outcomes and normal pregnant women. | 2001 | Scand. J. Infect. Dis. | pmid:11525356 |
Schlienger RG et al. | Risk of cataract in patients treated with statins. | 2001 | Arch. Intern. Med. | pmid:11525705 |
Oei J and Lui K | A placebo-controlled trial of low-dose erythromycin to promote feed tolerance in preterm infants. | 2001 | Acta Paediatr. | pmid:11529540 |
Miyashita N et al. | [A case of Coxiella burnetii pneumonia in an adult]. | 2001 | Nihon Kokyuki Gakkai Zasshi | pmid:11530397 |
Celik H et al. | Effects of erythromycin on stretch-induced contractile activity of isolated myometrium from pregnant women. | 2001 | Acta Obstet Gynecol Scand | pmid:11531610 |