erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Griño JM et al. | Erythromycin and cyclosporine. | 1986 | Ann. Intern. Med. | pmid:3740694 |
Kirby BD et al. | Legionnaires' disease: clinical features of 24 cases. | 1978 | Ann. Intern. Med. | pmid:686539 |
Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
Saravolatz LD et al. | The compromised host and Legionnaires' disease. | 1979 | Ann. Intern. Med. | pmid:373543 |
Gump DW et al. | Legionnaires' disease in patients with associated serious disease. | 1979 | Ann. Intern. Med. | pmid:373544 |
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Sanford JP | Legionnaires' disease: one person's perspective. | 1979 | Ann. Intern. Med. | pmid:373555 |
Hassel B | Hypothermia from erythromycin. | 1991 | Ann. Intern. Med. | pmid:2048867 |
Green GR et al. | Treatment of bacterial endocarditis in patients with penicillin hypersensitivity. | 1967 | Ann. Intern. Med. | pmid:4382501 |
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Legionnaires' disease: diagnosis and management. | 1978 | Ann. Intern. Med. | pmid:343681 | |
Leroy F et al. | Dihydroergotamine-erythromycin-induced ergotism. | 1988 | Ann. Intern. Med. | pmid:3389610 |
JENSEN K and LASSEN HC | FULMINATING STAPHYLOCOCCAL INFECTIONS TREATED WITH FUCIDIN AND PENICILLIN OR SEMISYNTHETIC PENICILLIN. | 1964 | Ann. Intern. Med. | pmid:14159235 |
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Syphilis: recommended treatment schedules, 1976. Recommendations established by the Venereal Disease Control Advisory Committee. | 1976 | Ann. Intern. Med. | pmid:937929 | |
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Steere AC et al. | Treatment of the early manifestations of Lyme disease. | 1983 | Ann. Intern. Med. | pmid:6407378 |
Spach DH et al. | Intracerebral bacillary angiomatosis in a patient infected with human immunodeficiency virus. | 1992 | Ann. Intern. Med. | pmid:1558347 |
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Ampel NM et al. | Cutaneous abscess caused by Legionella micdadei in an immunosuppressed patient. | 1985 | Ann. Intern. Med. | pmid:3885816 |
McCabe RE et al. | Prosthetic valve endocarditis caused by Legionella pneumophila. | 1984 | Ann. Intern. Med. | pmid:6703545 |
Carson JL et al. | Acute liver disease associated with erythromycins, sulfonamides, and tetracyclines. | 1993 | Ann. Intern. Med. | pmid:8363168 |
Campanini M et al. | [A case of legionellosis treated with erythromycin]. | 1986 | Ann. Ital. Med. Int. | pmid:3275185 |
Siitonen S et al. | Effect of Lactobacillus GG yoghurt in prevention of antibiotic associated diarrhoea. | 1990 | Ann. Med. | pmid:2184848 |
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Andremont A and Tancrede C | Reduction of the aerobic Gram negative bacterial flora of the gastro-intestinal tract and prevention of traveller's diarrhea using oral erythromycin. | 1981 Nov-Dec | Ann. Microbiol. (Paris) | pmid:7036825 |
Reynaud A et al. | [Antibiotic sensitivity of 139 strains of Listeria serotyped by the National Reference Center in 1983]. | 1984 Nov-Dec | Ann. Microbiol. (Paris) | pmid:6442548 |
Ionesco H | [Transferable tetracycline resistance in "Clostridium difficile" (author's transl)]. | 1980 Mar-Apr | Ann. Microbiol. (Paris) | pmid:6247949 |
Tytgat F | [Activity of seven antimicrobial agents against "Bacteroides fragilis" (author's transl)]. | 1980 Jan-Feb | Ann. Microbiol. (Paris) | pmid:6899739 |
Donaldson MH and Thurman WG | An approach to acute respiratory infection in children. | 1967 | Ann. N. Y. Acad. Sci. | pmid:4397880 |
Fujii R | Patterns of organisms in disease and in vitro sensitivity to kanamycin in comparison with other antibiotics. | 1966 | Ann. N. Y. Acad. Sci. | pmid:4960371 |
Griffith LJ | Development of resistance to kanamycin. | 1966 | Ann. N. Y. Acad. Sci. | pmid:4960372 |
Tourtellotte ME et al. | Protein synthesis in mycoplasma. | 1967 | Ann. N. Y. Acad. Sci. | pmid:5233752 |
Shepard MC | Cultivation and properties of T-strains of mycoplasma associated with nongonococcal urethritis. | 1967 | Ann. N. Y. Acad. Sci. | pmid:5233783 |
Tonzetich J and Friedman SD | The regulation of metabolism by the cellular elements in saliva. | 1965 | Ann. N. Y. Acad. Sci. | pmid:5214669 |
Johnson RC et al. | Experimental infection of the hamster with Borrelia burgdorferi. | 1988 | Ann. N. Y. Acad. Sci. | pmid:3190098 |
Lepper MH et al. | Patterns of transmission of staphylococci. | 1965 | Ann. N. Y. Acad. Sci. | pmid:4221874 |
SUTHERLAND JM | OBSERVATIONS ON RELATIONSHIPS BETWEEN DRUG THERAPY AND NEONATAL JAUNDICE. | 1963 | Ann. N. Y. Acad. Sci. | pmid:14085870 |
Smith CB et al. | Mycoplasma pneumoniae infections in volunteers. | 1967 | Ann. N. Y. Acad. Sci. | pmid:4861142 |
Godzeski CW et al. | The interaction of antibiotics, bacteria and the bacterial L-phase in vivo. | 1967 | Ann. N. Y. Acad. Sci. | pmid:4167700 |
Ross S | Staphylococcal infections in nurseries. | 1966 | Ann. N. Y. Acad. Sci. | pmid:5297742 |
Plorde JJ and Sherris JC | Staphylococcal resistance to antibiotics: origin, measurement, and epidemiology. | 1974 | Ann. N. Y. Acad. Sci. | pmid:4608264 |