erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Cimolai N | Ocular methicillin-resistant Staphylococcus aureus infections in a newborn intensive care cohort. | 2006 | Am. J. Ophthalmol. | pmid:16815280 |
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Okumoto M and Smolin G | Pneumococcal infections of the eye. | 1974 | Am. J. Ophthalmol. | pmid:4149786 |
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Genvert GI et al. | Erythema multiforme after use of topical sulfacetamide. | 1985 | Am. J. Ophthalmol. | pmid:3157322 |
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Bartley GB and Messenger MM | Outcome of tarsoconjunctival flap dehiscence after eyelid reconstruction. | 2002 | Am. J. Ophthalmol. | pmid:12383835 |
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MARR WG et al. | Further studies on the effect of agents on regeneration of corneal epithelium. | 1954 | Am. J. Ophthalmol. | pmid:13148284 |
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Ghione M et al. | Research on factors influencing experimental chemotherapy tests in trachoma. | 1967 | Am. J. Ophthalmol. | pmid:6067316 |
Newman PE et al. | A cluster of cases of Mycobacterium chelonei keratitis associated with outpatient office procedures. | 1984 | Am. J. Ophthalmol. | pmid:6702973 |
Granovsky-Grisaru S et al. | Effects of erythromycin on contractility of isolated myometrium from pregnant rats. | 1998 | Am. J. Obstet. Gynecol. | pmid:9465824 |
Bowie WR et al. | Efficacy of treatment regimens for lower urogenital Chlamydia trachomatis infection in women. | 1982 | Am. J. Obstet. Gynecol. | pmid:7055176 |
McGregor JA et al. | Cervicovaginal microflora and pregnancy outcome: results of a double-blind, placebo-controlled trial of erythromycin treatment. | 1990 | Am. J. Obstet. Gynecol. | pmid:2240110 |
Andrews JI et al. | Group B streptococci causing neonatal bloodstream infection: antimicrobial susceptibility and serotyping results from SENTRY centers in the Western Hemisphere. | 2000 | Am. J. Obstet. Gynecol. | pmid:11035326 |
Charles AG et al. | Asymptomatic gonorrhea in prenatal patients. | 1970 | Am. J. Obstet. Gynecol. | pmid:5505990 |
Mercer BM et al. | Prenatal screening for group B Streptococcus. I. Impact of antepartum screening on antenatal prophylaxis and intrapartum care. | 1995 | Am. J. Obstet. Gynecol. | pmid:7573254 |
Campbell WF and Dodson MG | Clindamycin therapy for Chlamydia trachomatis in women. | 1990 | Am. J. Obstet. Gynecol. | pmid:2178426 |
Silverman NS et al. | A randomized, prospective trial comparing amoxicillin and erythromycin for the treatment of Chlamydia trachomatis in pregnancy. | 1994 | Am. J. Obstet. Gynecol. | pmid:8141211 |
Friberg J | Genital mycoplasma infections. | 1978 | Am. J. Obstet. Gynecol. | pmid:362924 |
Klebanoff MA et al. | Outcome of the Vaginal Infections and Prematurity Study: results of a clinical trial of erythromycin among pregnant women colonized with group B streptococci. | 1995 | Am. J. Obstet. Gynecol. | pmid:7755068 |
Quinn PA et al. | Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas. | 1983 | Am. J. Obstet. Gynecol. | pmid:6849358 |
Louik C et al. | Erythromycin use during pregnancy in relation to pyloric stenosis. | 2002 | Am. J. Obstet. Gynecol. | pmid:11854652 |
Ehsanipoor RM et al. | A retrospective review of ampicillin-sulbactam and amoxicillin + clavulanate vs cefazolin/cephalexin and erythromycin in the setting of preterm premature rupture of membranes: maternal and neonatal outcomes. | 2008 | Am. J. Obstet. Gynecol. | pmid:18455521 |
Jones RB | New treatments for Chlamydia trachomatis. | 1991 | Am. J. Obstet. Gynecol. | pmid:2039033 |
Yost NP et al. | An appraisal of treatment guidelines for antepartum community-acquired pneumonia. | 2000 | Am. J. Obstet. Gynecol. | pmid:10920320 |
Lin KJ et al. | Safety of macrolides during pregnancy. | 2013 | Am. J. Obstet. Gynecol. | pmid:23254249 |
McGregor JA et al. | Antimicrobial therapy in preterm premature rupture of membranes: results of a prospective, double-blind, placebo-controlled trial of erythromycin. | 1991 | Am. J. Obstet. Gynecol. | pmid:1892190 |
Croak A et al. | Predominance of serotype V and frequency of erythromycin resistance in Streptococcus agalactiae in Ohio. | 2003 | Am. J. Obstet. Gynecol. | pmid:12748459 |
Hussain N and Herson VC | Erythromycin use during pregnancy in relation to pyloric stenosis. | 2002 | Am. J. Obstet. Gynecol. | pmid:12237674 |
Milwidsky A et al. | Direct inhibition of proteases and cervical plasminogen activator by antibiotics. | 1992 | Am. J. Obstet. Gynecol. | pmid:1536241 |
Johnson RB | The role of azalide antibiotics in the treatment of Chlamydia. | 1991 | Am. J. Obstet. Gynecol. | pmid:1645503 |
Romero R et al. | Eradication of Ureaplasma urealyticum from the amniotic fluid with transplacental antibiotic treatment. | 1992 | Am. J. Obstet. Gynecol. | pmid:1536243 |
Danielian P | Erythromycin, motilin, and meconium. | 1992 | Am. J. Obstet. Gynecol. | pmid:1536263 |
Keelan JA et al. | Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. | 2011 | Am. J. Obstet. Gynecol. | pmid:21481833 |
Kundsin RB et al. | Ureaplasma urealyticum resistance to erythromycin: confirmed by clinical trial. | 1992 | Am. J. Obstet. Gynecol. | pmid:1615998 |