erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Bach MC | The chemotherapy of infections due to nocardia. | 1975 | Int J Clin Pharmacol Biopharm | pmid:1099020 |
Komine M and Tamaki K | An open trial of oral macrolide treatment for psoriasis vulgaris. | 2000 | J. Dermatol. | pmid:10989574 |
Shivakumar AG et al. | Studies on the synthesis of plasmid-coded proteins and their control in Bacillus subtilis minicells. | 1979 | Plasmid | pmid:109873 |
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Khan AA et al. | Ketolide ABT-773 is active against Toxoplasma gondii. | 2000 | J. Antimicrob. Chemother. | pmid:10980181 |
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Goldstein EJ et al. | Comparative in vitro activities of ABT-773 against aerobic and anaerobic pathogens isolated from skin and soft-tissue animal and human bite wound infections. | 2000 | Antimicrob. Agents Chemother. | pmid:10952607 |
Pendland SL et al. | In vitro activities of a new ketolide, ABT-773, alone and in combination with amoxicillin, metronidazole, or tetracycline against Helicobacter pylori. | 2000 | Antimicrob. Agents Chemother. | pmid:10952605 |
Masuda N et al. | Contribution of the MexX-MexY-oprM efflux system to intrinsic resistance in Pseudomonas aeruginosa. | 2000 | Antimicrob. Agents Chemother. | pmid:10952562 |
Lakritz J et al. | Pharmacokinetics of erythromycin estolate and erythromycin phosphate after intragastric administration to healthy foals. | 2000 | Am. J. Vet. Res. | pmid:10951982 |
Lozniewski A et al. | Comparison of the in vitro activity of pristinamycin and quinupristin/dalfopristin against Streptococcus pneumoniae. | 2000 | Pathol. Biol. | pmid:10949841 |
Johnston WS | Eradication of STR agalactiae from infected herds using erythromycin. | 1975 | Vet. Rec. | pmid:1094673 |
Wardrop J et al. | Determination of erythromycin and related substances in enteric-coated tablet formulations by reversed-phase liquid chromatography. | 2000 | J Pharm Sci | pmid:10944374 |
De Soyza A et al. | An unusual case of pulmonary abscess. | 2000 | J. Infect. | pmid:10942653 |
Burkhart CN et al. | Synergistic activity of benzoyl peroxide and erythromycin. | 2000 Sep-Oct | Skin Pharmacol. Appl. Skin Physiol. | pmid:10940820 |
Slain D et al. | Variability in activity of hepatic CYP3A4 in patients infected with HIV. | 2000 | Pharmacotherapy | pmid:10939550 |
Leaf T et al. | Precursor-directed biosynthesis of 6-deoxyerythronolide B analogs in Streptomyces coelicolor: understanding precursor effects. | 2000 Jul-Aug | Biotechnol. Prog. | pmid:10933827 |
Wasilewski MM et al. | Comparative efficacy of 5 days of dirithromycin and 7 days of erythromycin in skin and soft tissue infections. | 2000 | J. Antimicrob. Chemother. | pmid:10933649 |
Schultz MJ et al. | Intravenous infusion of erythromycin inhibits CXC chemokine production, but augments neutrophil degranulation in whole blood stimulated with Streptococcus pneumoniae. | 2000 | J. Antimicrob. Chemother. | pmid:10933646 |
Eady EA et al. | Antibiotic resistance patterns of aerobic coryneforms and furazolidone-resistant Gram-positive cocci from the skin surface of the human axilla and fourth toe cleft. | 2000 | J. Antimicrob. Chemother. | pmid:10933642 |
Dreassi E et al. | High-performance liquid chromatographic assay of erythromycin from biological matrix using electrochemical or ultraviolet detection. | 2000 | Analyst | pmid:10932853 |
Hashemi K et al. | Comparison of antibiotic drops placed in the conjunctival cul-de-sac to antibiotic ointment applied to the lid margin in reduction of bacterial colonization on the lid margin. | 2000 | Cornea | pmid:10928757 |
Hammerschlag MR | Treatment of Chlamydia pneumoniae. | 2000 | Int. J. Antimicrob. Agents | pmid:10926449 |
Lin HC et al. | Erythromycin inhibits beta2-integrins (CD11b/CD18) expression, interleukin-8 release and intracellular oxidative metabolism in neutrophils. | 2000 | Respir Med | pmid:10926336 |
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Joshi A et al. | Palmar erythema nodosum. | 2000 | J. Dermatol. | pmid:10920594 |
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Zhang Y et al. | Pentamidine inhibits mitochondrial intron splicing and translation in Saccharomyces cerevisiae. | 2000 | RNA | pmid:10917591 |
Rudolph KM et al. | Serotype distribution and antimicrobial resistance patterns of invasive isolates of Streptococcus pneumoniae: Alaska, 1991-1998. | 2000 | J. Infect. Dis. | pmid:10915080 |
Kobayashi Y et al. | Development of a competitive polymerase chain reaction assay for the ruminal bacterium Butyrivibrio fibrisolvens OB156 and its use for tracking an OB156-derived recombinant. | 2000 | FEMS Microbiol. Lett. | pmid:10913703 |
Lin FY et al. | Antibiotic susceptibility profiles for group B streptococci isolated from neonates, 1995-1998. | 2000 | Clin. Infect. Dis. | pmid:10913400 |
Lacey RW | Antibiotic resistance plasmids of Staphylococcus aureus and their clinical importance. | 1975 | Bacteriol Rev | pmid:1091256 |
Zueva VS et al. | [Dynamics of the antibiotic sensitivity of the staphylococci in suppurative, inflammatory foci in patients during the period of the hospital stay]. | 1975 | Antibiotiki | pmid:1091206 |
Stratton-Phelps M et al. | Risk of adverse effects in pneumonic foals treated with erythromycin versus other antibiotics: 143 cases (1986-1996). | 2000 | J. Am. Vet. Med. Assoc. | pmid:10909450 |