erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
Rhinitis D012220 10 associated lipids
Skin Ulcer D012883 6 associated lipids
Heart Diseases D006331 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Multiple Myeloma D009101 13 associated lipids
Quadriplegia D011782 4 associated lipids
Pain, Postoperative D010149 13 associated lipids
Porphyrias D011164 2 associated lipids
Femoral Fractures D005264 7 associated lipids
Hematuria D006417 13 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Endocarditis, Bacterial D004697 5 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Obesity D009765 29 associated lipids
Bradycardia D001919 13 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Intraoperative Complications D007431 5 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Eye Diseases D005128 12 associated lipids
Salpingitis D012488 2 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Fractures, Open D005597 3 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Crohn Disease D003424 12 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Cholestasis D002779 23 associated lipids
Sinusitis D012852 9 associated lipids
Glomerulonephritis D005921 35 associated lipids
Sepsis D018805 11 associated lipids
Nervous System Diseases D009422 37 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Ataxia D001259 20 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Wound Infection D014946 12 associated lipids
Bacteriuria D001437 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Kozak PP et al. Administration of erythromycin to patients on theophylline. 1977 J. Allergy Clin. Immunol. pmid:874213
Ohba M et al. Effect of clarithromycin on the bioavailability of cyclosporin in rats. 1996 Biol. Pharm. Bull. pmid:8741585
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Ripoll L et al. Interaction of macrolides with alpha dornase during DNA hydrolysis. 1996 J. Antimicrob. Chemother. pmid:8737148
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Gómez-Lechón MJ et al. Evidence of antibodies to erythromycin in serum of a patient following an episode of acute drug-induced hepatitis. 1996 Clin. Exp. Allergy pmid:8735873
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Box SA and Lee MR A systemic reaction following exposure to a pyrethroid insecticide. 1996 Hum Exp Toxicol pmid:8735461
Moore JE et al. Erythromycin-resistant thermophilic Campylobacter species isolated from pigs. 1996 Vet. Rec. pmid:8730692
Lopes Cardoso FL et al. Rhodococcus equi mastoiditis in a patient with AIDS. 1996 Clin. Infect. Dis. pmid:8729214
Brouqui P et al. Eucaryotic cells protect Borrelia burgdorferi from the action of penicillin and ceftriaxone but not from the action of doxycycline and erythromycin. 1996 Antimicrob. Agents Chemother. pmid:8726038
Fujii T et al. Inhibitory effect of erythromycin on interleukin 8 production by 1 alpha,25-dihydroxyvitamin D3-stimulated THP-1 cells. 1996 Antimicrob. Agents Chemother. pmid:8726037
Champney WS and Burdine R 50S ribosomal subunit synthesis and translation are equivalent targets for erythromycin inhibition in Staphylococcus aureus. 1996 Antimicrob. Agents Chemother. pmid:8723490
van Hoogdalem EJ et al. Evaluation of the effect of zinc acetate on the stratum corneum penetration kinetics of erythromycin in healthy male volunteers. 1996 Skin Pharmacol. pmid:8722604
Hall G et al. Elimination of bacteraemia after dental extraction: comparison of erythromycin and clindamycin for prophylaxis of infective endocarditis. 1996 J. Antimicrob. Chemother. pmid:8722544
Khan MA et al. A reverse transcriptase-PCR based assay for in-vitro antibiotic susceptibility testing of Chlamydia pneumoniae. 1996 J. Antimicrob. Chemother. pmid:8722533
Zimmermann T et al. Influence of the antibiotics erythromycin and azithromycin on the pharmacokinetics and pharmacodynamics of midazolam. 1996 Arzneimittelforschung pmid:8720318
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Ferraro AL et al. The antimicrobial susceptibility of Streptococcus pyogenes isolates from the Philadelphia area. 1995 Adv. Exp. Med. Biol. pmid:8718607
Mortensen JE and McDowell T Streptococcus pyogenes: resistant, tolerant, neither or both? 1995 Adv. Exp. Med. Biol. pmid:8718606
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Vanderhoof JA et al. Treatment of cyclic vomiting in childhood with erythromycin. 1995 J. Pediatr. Gastroenterol. Nutr. pmid:8708873
Nichterlein T et al. RP 59500, a streptogramin derivative, is effective in murine listeriosis. 1996 J Chemother pmid:8708741
Arranz-Caso JA et al. Prolonged colonic pseudo-obstruction (Ogilvie syndrome) in an older woman resolved with conservative treatment. 1996 J Am Geriatr Soc pmid:8708296
Paz HL et al. Motility agents for the placement of weighted and unweighted feeding tubes in critically ill patients. 1996 Intensive Care Med pmid:8708166
Zanetti S et al. In-vitro activity of 3-azinomethyl-rifamycin (SPA-S-565) against Chlamydia trachomatis. 1996 J. Antimicrob. Chemother. pmid:8707747
Higgins SP Chlamydial infection in women. 1996 Br J Gen Pract pmid:8703535
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McBride MJ and Baker SA Development of techniques to genetically manipulate members of the genera Cytophaga, Flavobacterium, Flexibacter, and Sporocytophaga. 1996 Appl. Environ. Microbiol. pmid:8702294
Wasteson Y et al. Characterization of tetracycline and erythromycin resistance in Actinobacillus pleuropneumoniae. 1996 Vet. Microbiol. pmid:8701576
Cadisch R et al. [Exacerbation of pseudoparalytic myasthenia gravis following azithromycin (Zithromax)]. 1996 Schweiz Med Wochenschr pmid:8701248
Koizumi A et al. [Effect of prolonged administration of erythromycin on the drug sensitivity and the biological properties of Streptococcus pneumoniae]. 1996 Kansenshogaku Zasshi pmid:8699091
Horowitz MS and Smith LG Vegetative bacterial endocarditis on the prolapsing mitral valve. Echocardiographic evaluation. 1977 Arch. Intern. Med. pmid:869651
Hall JE and Harmer M Erythromycin as a prokinetic agent in children. 1996 Anaesthesia pmid:8694177
Sanchez MA and Rorat E Fine needle aspiration diagnosis of intramuscular bacillary angiomatosis. A case report. 1996 Jul-Aug Acta Cytol. pmid:8693899
Bailey DG et al. Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice. 1996 Clin. Pharmacol. Ther. pmid:8689808
Matschiner S et al. Optimization of topical erythromycin formulations by ion pairing. 1995 Skin Pharmacol. pmid:8688198
Burgin S and Spencer DC Bacillary angiomatosis--another South African case. 1996 S. Afr. Med. J. pmid:8685799
Edelman K et al. Detection of Bordetella pertussis by polymerase chain reaction and culture in the nasopharynx of erythromycin-treated infants with pertussis. 1996 Pediatr. Infect. Dis. J. pmid:8684877
El-Chaar GM et al. Randomized, double blind comparison of brand and generic antibiotic suspensions: II. A study of taste and compliance in children. 1996 Pediatr. Infect. Dis. J. pmid:8684871
Samulak KM et al. Randomized, double blind comparison of brand and generic antibiotic suspensions: I. A study of taste in adults. 1996 Pediatr. Infect. Dis. J. pmid:8684870
Faghih R et al. Synthesis and antibacterial activity of 6-deoxysporeamicin A. 1996 J. Antibiot. pmid:8682729
Griesgraber G et al. 3-Keto-11,12-carbazate derivatives of 6-O-methylerythromycin A synthesis and in vitro activity. 1996 J. Antibiot. pmid:8682724
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Backström M and Kuusela AL [Unilateral pulmonary edema in an infant]. 1995 Duodecim pmid:8681845
Sturm A et al. [Treatment of radiotherapy-induced gastroparesis with erythromycin]. 1996 Dtsch. Med. Wochenschr. pmid:8681733
Coulter WA et al. Dental anxiety and the absorption of orally administered erythromycin stearate. 1995 Oral Surg Oral Med Oral Pathol Oral Radiol Endod pmid:8680971
Rowbury RJ et al. Sensitization to acid induced by sodium ions in Escherichia coli: dependence of (p)ppGpp and cAMP and suppression of the relA-associated defect by mutations in envZ. 1996 Microbios pmid:8676748
Zhou D and Apicella MA Plasmids with erythromycin resistance and catechol 2,3-dioxygenase- or beta-galactosidase-encoding gene cassettes for use in Neisseria spp. 1996 Gene pmid:8675023
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Aleksandrova AE and Vinogradova TI [Immunotropic activity of antimicrobial agents used in tuberculosis]. 1996 Probl Tuberk pmid:8657696
King DE et al. Effectiveness of erythromycin in the treatment of acute bronchitis. 1996 J Fam Pract pmid:8656171
Packman AM et al. Treatment of acne vulgaris: combination of 3% erythromycin and 5% benzoyl peroxide in a gel compared to clindamycin phosphate lotion. 1996 Int. J. Dermatol. pmid:8655242
Kligman AM The treatment of acne. Part III: antibacterials. 1995 Cutis pmid:8654122
Mashkilleyson AL et al. Treatment of syphilis with azithromycin. 1996 Int J STD AIDS pmid:8652720
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Dam M et al. Mutations in domain II of 23 S rRNA facilitate translation of a 23 S rRNA-encoded pentapeptide conferring erythromycin resistance. 1996 J. Mol. Biol. pmid:8648637
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Thompson D and Oster G Use of terfenadine and contraindicated drugs. 1996 JAMA pmid:8614120
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The choice of antibacterial drugs. 1996 Med Lett Drugs Ther pmid:8598824
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Lucier TS et al. Transition mutations in the 23S rRNA of erythromycin-resistant isolates of Mycoplasma pneumoniae. 1995 Antimicrob. Agents Chemother. pmid:8593017
Bental T et al. Chronic Q fever of pregnancy presenting as Coxiella burnetii placentitis: successful outcome following therapy with erythromycin and rifampin. 1995 Clin. Infect. Dis. pmid:8589167
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Radulovic S et al. In vitro and in vivo antibiotic susceptibilities of ELB rickettsiae. 1995 Antimicrob. Agents Chemother. pmid:8585746
Hamzehpour MM et al. OprK and OprM define two genetically distinct multidrug efflux systems in Pseudomonas aeruginosa. 1995 Antimicrob. Agents Chemother. pmid:8585714
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Tinanoff N et al. Dental treatment of Papillon-Lefèvre syndrome: 15-year follow-up. 1995 J. Clin. Periodontol. pmid:8583017
Minocha A et al. Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. 1995 Aliment. Pharmacol. Ther. pmid:8580273
Slomiany BL et al. Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents. 1995 Scand. J. Gastroenterol. Suppl. pmid:8578215
Masclee AA et al. Effect of antrectomy and truncal vagotomy on erythromycin induced pancreatic polypeptide secretion. 1995 Regul. Pept. pmid:8577928