erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
Rhinitis D012220 10 associated lipids
Skin Ulcer D012883 6 associated lipids
Heart Diseases D006331 8 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Multiple Myeloma D009101 13 associated lipids
Quadriplegia D011782 4 associated lipids
Pain, Postoperative D010149 13 associated lipids
Porphyrias D011164 2 associated lipids
Femoral Fractures D005264 7 associated lipids
Hematuria D006417 13 associated lipids
Labyrinth Diseases D007759 3 associated lipids
Weight Gain D015430 101 associated lipids
Cardiovascular Diseases D002318 24 associated lipids
Abnormalities, Drug-Induced D000014 10 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Endocarditis, Bacterial D004697 5 associated lipids
Staphylococcal Infections D013203 15 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Leukemia P388 D007941 43 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Obesity D009765 29 associated lipids
Bradycardia D001919 13 associated lipids
Prostatic Hyperplasia D011470 20 associated lipids
Intraoperative Complications D007431 5 associated lipids
Drug Hypersensitivity D004342 20 associated lipids
Eye Diseases D005128 12 associated lipids
Salpingitis D012488 2 associated lipids
Leukemia D007938 74 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Fractures, Open D005597 3 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Crohn Disease D003424 12 associated lipids
Arthritis, Infectious D001170 8 associated lipids
Prosthesis-Related Infections D016459 7 associated lipids
Cholestasis D002779 23 associated lipids
Sinusitis D012852 9 associated lipids
Glomerulonephritis D005921 35 associated lipids
Sepsis D018805 11 associated lipids
Nervous System Diseases D009422 37 associated lipids
Enterocolitis, Pseudomembranous D004761 8 associated lipids
Ataxia D001259 20 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Cross Infection D003428 9 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Staphylococcal Skin Infections D013207 9 associated lipids
Wound Infection D014946 12 associated lipids
Bacteriuria D001437 7 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Khair OA et al. Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells. 1995 Eur. Respir. J. pmid:8575568
Kerr JR and Moore JE Potential for erythromycin resistance in porcine Campylobacter species. 1995 Trends Microbiol. pmid:8574518
Lynch HC and Bushell ME The physiology of erythromycin biosynthesis in cyclic fed batch culture. 1995 Microbiology (Reading, Engl.) pmid:8574403
Goswami BB et al. Physico-chemical properties and biological activities of erythromycin nalidixate. 1995 Arzneimittelforschung pmid:8573228
Roberts MC et al. Transferable erythromycin resistance in Listeria spp. isolated from food. 1996 Appl. Environ. Microbiol. pmid:8572704
Ishiura Y et al. Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome. 1995 Respir Med pmid:8570882
Tait A and Knowles JK Characterization of mitochondrial and cytoplasmic ribosomes from Paramecium aurelia. 1977 J. Cell Biol. pmid:856828
Christie CD et al. Containment of pertussis in the regional pediatric hospital during the Greater Cincinnati epidemic of 1993. 1995 Infect Control Hosp Epidemiol pmid:8568199
Cherry JD Nosocomial pertussis in the nineties. 1995 Infect Control Hosp Epidemiol pmid:8568198
Leyh F [Syphilis therapy--results of an inquiry]. 1977 Hautarzt pmid:856770
Martins C et al. Allergic contact dermatitis from erythromycin. 1995 Contact Derm. pmid:8565504
Kelly DJ et al. Rickettsia tsutsugamushi infection in cell culture: antibiotic susceptibility determined by flow cytometry. 1995 Am. J. Trop. Med. Hyg. pmid:8561261
Arroyo J and Medoff G Mycobacterium chelonei infection: successful treatment based on a radiometric susceptibility test. 1977 Antimicrob. Agents Chemother. pmid:856032
Allen NE Macrolide resistance in Staphylococcus aureus: inducers of macrolide resistance. 1977 Antimicrob. Agents Chemother. pmid:856018
Moriyama H et al. Evaluation of endoscopic sinus surgery for chronic sinusitis: post-operative erythromycin therapy. 1995 Rhinology pmid:8560171
Mitsuyama T et al. Inhibition by erythromycin of superoxide anion production by human polymorphonuclear leukocytes through the action of cyclic AMP-dependent protein kinase. 1995 Respiration pmid:8560094
Tauch A et al. The Corynebacterium xerosis composite transposon Tn5432 consists of two identical insertion sequences, designated IS1249, flanking the erythromycin resistance gene ermCX. 1995 Plasmid pmid:8559800
Tateishi T et al. Omeprazole does not affect measured CYP3A4 activity using the erythromycin breath test. 1995 Br J Clin Pharmacol pmid:8554946
Fujii T et al. Long term effect of erythromycin therapy in patients with chronic Pseudomonas aeruginosa infection. 1995 Thorax pmid:8553295
Kawahara S et al. Inhibitory effect of ofloxacin on acute exacerbations of chronic respiratory tract infections in comparison with erythromycin. 1995 Drugs pmid:8549382
Fujimura M et al. Additive effect of continuous low dose ofloxacin on erythromycin therapy for sinobronchial syndrome. 1995 Drugs pmid:8549380
Saito A and Gaja M In vitro and in vivo activities of sparfloxacin in Legionella infections. 1995 Drugs pmid:8549320
Morrissey I and Smith JT Activity of new 4-quinolones in combination with erythromycin or tetracycline against S. pneumoniae. 1995 Drugs pmid:8549311
Bojar RA et al. Direct analysis of resistance in the cutaneous microflora during treatment of acne vulgaris with topical 1% nadifloxacin and 2% erythromycin. 1995 Drugs pmid:8549289
Stein CM et al. Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. 1996 Clin. Pharmacol. Ther. pmid:8549033
Brown GR Erythromycin-induced hypotension. 1995 Ann Pharmacother pmid:8547744
Ducloux D et al. [Pseudo-cholangitis, a form of erythromycin-induced hepatitis]. 1995 Presse Med pmid:8545387
Kenney DG et al. Development of reactive arthritis and resistance to erythromycin and rifampin in a foal during treatment for Rhodococcus equi pneumonia. 1994 Equine Vet. J. pmid:8542848
Tissi L et al. In vivo efficacy of azithromycin in treatment of systemic infection and septic arthritis induced by type IV group B Streptococcus strains in mice: comparative study with erythromycin and penicillin G. 1995 Antimicrob. Agents Chemother. pmid:8540695
Veber B and Pocidalo JJ [The particular case of azalides: antibiotic diapedesis. Experimental data from a murine model of pneumococcal pneumonia]. 1995 Pathol. Biol. pmid:8539075
Lagrange PH [Azithromycin, pharmacodynamic evaluation in animal models]. 1995 Pathol. Biol. pmid:8539074
Philippon A et al. [Azithromycin: critical points]. 1995 Pathol. Biol. pmid:8539070
Pechère JC [Effect of the molecular structure of azithromycin on pharmacokinetics and the antimicrobial activity]. 1995 Pathol. Biol. pmid:8539069
Littenberg B et al. A randomized controlled trial of oral albuterol in acute cough. 1996 J Fam Pract pmid:8537805
Hosie J et al. A comparison of 5 days of dirithromycin and 7 days of clarithromycin in acute bacterial exacerbation of chronic bronchitis. 1995 J. Antimicrob. Chemother. pmid:8537264
Doucet-Populaire F et al. Acquired resistance in Mycobacterium avium complex strains isolated from AIDS patients and beige mice during treatment with clarithromycin. 1995 J. Antimicrob. Chemother. pmid:8537260
Shiba Y et al. Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs. 1996 Gastroenterology pmid:8536863
Hoppe JE and Tschirner T Comparison of media for agar dilution susceptibility testing of Bordetella pertussis and Bordetella parapertussis. 1995 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8536725
Izumikawa K et al. [The therapeutic effect of doxycycline (Vibramycin) on pneumonia due to mycoplasma pneumoniae (author's transl)]. 1977 Jpn J Antibiot pmid:853569
Benzamycin gel for acne. 1995 Drug Ther Bull pmid:8529541
Lestico MR and Smith AD Stevens-Johnson syndrome following erythromycin administration. 1995 Am J Health Syst Pharm pmid:8528839
Tee W et al. Emergence of multidrug resistance in Campylobacter jejuni isolates from three patients infected with human immunodeficiency virus. 1995 Clin. Infect. Dis. pmid:8527556
Kelentey BA and Kelentey BJ [Excretion of erythromycin, clindamycin and lincomycin into the saliva]. 1995 Fogorv Sz pmid:8522016
González Carro P et al. [Acute pancreatitis and erythromycin]. 1995 Rev Esp Enferm Dig pmid:8519548
Baird RM Antimicrobial drug use in hospitals. 1977 Can Med Assoc J pmid:851926
Suriñach JM et al. [Acute pancreatitis from erythromycin]. 1993 Rev Clin Esp pmid:8516513
Nakata M et al. Synthetic studies of erythromycin derivatives. Synthesis and antimicrobial activities of 3''-EPI-erythromycin A and (9S)-11-dehydroxy-9-deoxo-9-hydroxy-11- oxoerythromycin A. 1993 J. Antibiot. pmid:8514636
Kepczyk T et al. Effect of intravenous erythromycin on gastric emptying. 1993 May-Jun Gastrointest. Endosc. pmid:8514093
Narchi P et al. Interactions of pre-operative erythromycin administration with general anaesthesia. 1993 Can J Anaesth pmid:8513524
Suata K et al. Antimicrobial susceptibility patterns and resistance transferability among Bacteroides fragilis group isolates from patients with appendicitis in Bali, Indonesia. 1993 Clin. Infect. Dis. pmid:8513066
Siminoski K Persistent fever due to occult dental infection: case report and review. 1993 Clin. Infect. Dis. pmid:8513063
Varga DW Learning in the real world. 1993 J Ky Med Assoc pmid:8509688
Roberts GA et al. Heterologous expression in Escherichia coli of an intact multienzyme component of the erythromycin-producing polyketide synthase. 1993 Eur. J. Biochem. pmid:8508800
Kawamura O et al. Effect of erythromycin derivative EM523L on human interdigestive gastrointestinal tract. 1993 Dig. Dis. Sci. pmid:8508696
Lemaire F et al. [Erythromycin therapy of incidences of superinfection in chronic respiratory insufficiency]. 1977 Nouv Presse Med pmid:850633
Altemeir WA and Ayoub EM Erythromycin prophylaxis for pertussis. 1977 Pediatrics pmid:850603
Danielson ND et al. Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. 1993 J Pharm Biomed Anal pmid:8504183
Sacristán JA et al. Ototoxicity of erythromycin in man: electrophysiologic approach. 1993 Am J Otol pmid:8503495
Oğünç G et al. [Legionnaires' disease following kidney transplantation]. 1993 Mikrobiyol Bul pmid:8502185
Faghin R et al. Acid degradation studies of 6-deoxyerythromycin A. 1993 J. Antibiot. pmid:8501017
Watanabe Y et al. Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin. 1993 J. Antibiot. pmid:8501007
Levison ME et al. In vitro activity and clinical efficacy of clindamycin in the treatment of infections due to anaerobic bacteria. 1977 J. Infect. Dis. pmid:850091
Iino Y et al. Erythromycin therapy for otitis media with effusion in sinobronchial syndrome. 1993 Arch. Otolaryngol. Head Neck Surg. pmid:8499096
Prather CM et al. Gastric axial forces in experimentally delayed and accelerated gastric emptying. 1993 Am. J. Physiol. pmid:8498519
Tredaniel J et al. Diffuse panbronchiolitis: efficacy of low-dose erythromycin. 1993 Respir Med pmid:8497706
Edelstein PH and Edelstein MA In vitro activity of RP 74501-RP 74502, a novel streptogramin antimicrobial mixture, against clinical isolates of Legionella species. 1993 Antimicrob. Agents Chemother. pmid:8494390
Foweraker JE et al. Ecology of Haemophilus influenzae and Haemophilus parainfluenzae in sputum and saliva and effects of antibiotics on their distribution in patients with lower respiratory tract infections. 1993 Antimicrob. Agents Chemother. pmid:8494378
Tankovic J et al. Antimicrobial susceptibility of Pediococcus spp. and genetic basis of macrolide resistance in Pediococcus acidilactici HM3020. 1993 Antimicrob. Agents Chemother. pmid:8494376
Tateda K et al. Effects of sub-MICs of erythromycin and other macrolide antibiotics on serum sensitivity of Pseudomonas aeruginosa. 1993 Antimicrob. Agents Chemother. pmid:8494362
Piras G et al. Cloning and sequencing of the low-affinity penicillin-binding protein 3r-encoding gene of Enterococcus hirae S185: modular design and structural organization of the protein. 1993 J. Bacteriol. pmid:8491705
Grøndahl TO and Langmoen IA Epileptogenic effect of antibiotic drugs. 1993 J. Neurosurg. pmid:8487076
Soriano F and Fernández-Roblas R High rates of erythromycin-resistant Streptococcus pneumoniae among penicillin-resistant strains. 1993 J. Antimicrob. Chemother. pmid:8486579
Savolainen S et al. Peritonsillar abscess. Clinical and microbiologic aspects and treatment regimens. 1993 Arch. Otolaryngol. Head Neck Surg. pmid:8484941
Doménech J et al. [Evaluation of the possible ototoxicity of josamycin by high frequency audiometry]. 1993 An Otorrinolaringol Ibero Am pmid:8484488
Rathore MH and Jenkins SG Group A beta-hemolytic Streptococcus: issue of resistance. 1993 Pediatr. Infect. Dis. J. pmid:8483636
Gustafsson BE et al. Prolonged induction of germfree bile acid pattern in conventional rats by antibiotics. 1977 Acta Med Scand pmid:848350
Orr PH et al. Randomized placebo-controlled trials of antibiotics for acute bronchitis: a critical review of the literature. 1993 J Fam Pract pmid:8482934
Ohtawa M et al. Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs. 1993 Gastroenterology pmid:8482446
Kawamura O et al. Effect of erythromycin on interdigestive gastrointestinal contractile activity and plasma motilin concentration in humans. 1993 Dig. Dis. Sci. pmid:8482186
Derby LE et al. Erythromycin-associated cholestatic hepatitis. 1993 Med. J. Aust. pmid:8479375
Müller O and Wettich K Clinical efficacy of dirithromycin in pharyngitis and tonsillitis. 1993 J. Antimicrob. Chemother. pmid:8478316
Derriennic M et al. Dirithromycin in the treatment of streptococcal pharyngitis. 1993 J. Antimicrob. Chemother. pmid:8478315
Bergogne-Bérézin E Tissue distribution of dirithromycin: comparison with erythromycin. 1993 J. Antimicrob. Chemother. pmid:8478314
Sides GD et al. Pharmacokinetics of dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478313
Labro MT et al. Modulation of human polymorphonuclear neutrophil function by macrolides: preliminary data concerning dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478312
Bauernfeind A In-vitro activity of dirithromycin in comparison with other new and established macrolides. 1993 J. Antimicrob. Chemother. pmid:8478311
Barry AL et al. Dirithromycin disc susceptibility tests: interpretative criteria and quality control parameters. 1993 J. Antimicrob. Chemother. pmid:8478310
Sides GD and Conforti PM Safety profile of dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478309
Varanese L Pharmacokinetics and safety of dirithromycin in the elderly. 1993 J. Antimicrob. Chemother. pmid:8478308
Derriennic M and Escande JP Dirithromycin in the treatment of skin and skin structure infections. 1993 J. Antimicrob. Chemother. pmid:8478307
Pozzi E Clinical efficacy of dirithromycin versus miocamycin in the treatment of acute bronchitis or acute exacerbations of chronic bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478306
Gaillat J A multicentre study comparing the safety and efficacy of dirithromycin with erythromycin in the treatment of bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478305
Sides GD Clinical efficacy of dirithromycin in acute exacerbations of chronic bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478304
Jacobson K Clinical efficacy of dirithromycin in pneumonia. 1993 J. Antimicrob. Chemother. pmid:8478303
Ruggiero G et al. Clinical efficacy of dirithromycin versus miocamycin in tonsillopharyngitis. 1993 J. Antimicrob. Chemother. pmid:8478300
Endou K et al. Implication of cohesive binding of a macrolide antibiotic, rokitamycin, to ribosomes from Staphylococcus aureus. 1993 J. Antibiot. pmid:8478265
Husfeldt P et al. Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin. 1993 Eur Arch Otorhinolaryngol pmid:8476582
Gannon H Ureaplasma urealyticum and its role in neonatal lung disease. 1993 Neonatal Netw pmid:8474408
Garlaschi ML et al. Antimicrobial resistance among clinical isolates of Haemophilus influenzae in northern Italy. Collaborative Study on Pediatric Infectious Diseases. 1993 Eur. J. Epidemiol. pmid:8472803
Smith GR and Thornton EA Effect of disturbance of the gastrointestinal microflora on the faecal excretion of Fusobacterium necrophorum biovar A. 1993 Epidemiol. Infect. pmid:8472777