erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kuwahara T et al. | Clinical characteristics and management of periesophageal vagal nerve injury complicating left atrial ablation of atrial fibrillation: lessons from eleven cases. | 2013 | J. Cardiovasc. Electrophysiol. | pmid:23551640 |
Lozada LE et al. | Development of pyloric stenosis after a 4-day course of oral erythromycin. | 2013 | Pediatr Emerg Care | pmid:23558266 |
Cuello-GarcÃa CA et al. | Treating BCG-induced disease in children. | 2013 | Cochrane Database Syst Rev | pmid:23440826 |
Jersild Jespersen M et al. | [Sparse effect of long-term treatment with macrolides in patients with chronic obstructive pulmonary disease]. | 2013 | Ugeskr. Laeg. | pmid:23462037 |
Jiang M and Pfeifer BA | Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. | 2013 | Metab. Eng. | pmid:23747605 |
Xia Q et al. | Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. | 2013 | BMC Microbiol. | pmid:23767761 |
Guan Y et al. | [Effect of combination of sub-MIC sodium houttuyfonate and erythromycin on biofilm of Staphylococcus epidermidis]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23724685 |
Sugino K et al. | Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency. | 2013 | Intern. Med. | pmid:24292765 |
Goh S et al. | Phage Ï•C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains. | 2013 | MBio | pmid:24255122 |
Horácio AN et al. | The majority of adult pneumococcal invasive infections in Portugal are still potentially vaccine preventable in spite of significant declines of serotypes 1 and 5. | 2013 | PLoS ONE | pmid:24066064 |
Guo L et al. | Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | 2013 | Toxicol. Sci. | pmid:24052561 |
Guo MT et al. | Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. | 2013 | Chemosphere | pmid:24055024 |
Li YY et al. | Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. | 2013 | BMC Genomics | pmid:23902230 |
Cai G et al. | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. | 2013 | J. Nat. Prod. | pmid:24224794 |
Ong SJ et al. | Staphylococcus aureus keratitis: a review of hospital cases. | 2013 | PLoS ONE | pmid:24244625 |
Chroboczek T et al. | Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics. | 2013 | PLoS ONE | pmid:24260092 |
Ansari NN et al. | Treatment of chronic rhinosinusitis using erythromycin phonophoresis. | 2013 | Physiother Theory Pract | pmid:22891948 |
Fang J et al. | Dissecting the function of a protruding loop in AcrB trimerization. | 2013 | J. Biomol. Struct. Dyn. | pmid:22877148 |
Novy P et al. | Synergistic interactions of epigallocatechin gallate and oxytetracycline against various drug resistant Staphylococcus aureus strains in vitro. | 2013 | Phytomedicine | pmid:23485046 |
Chen DK et al. | [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. | 2013 | Zhonghua Yi Xue Za Zhi | pmid:24548451 |
Opdam FL et al. | Breath tests to phenotype drug disposition in oncology. | 2013 | Clin Pharmacokinet | pmid:23868281 |
Tsujimoto M et al. | Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. | 2013 | Toxins (Basel) | pmid:23965431 |
PetráÄková D et al. | Fitness and proteome changes accompanying the development of erythromycin resistance in a population of Escherichia coli grown in continuous culture. | 2013 | Microbiologyopen | pmid:23996919 |
Whitehead TR and Cotta MA | Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. | 2013 | Lett. Appl. Microbiol. | pmid:23297734 |
Broad J and Sanger GJ | The antibiotic azithromycin is a motilin receptor agonist in human stomach: comparison with erythromycin. | 2013 | Br. J. Pharmacol. | pmid:23190027 |
Hao H et al. | Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. | 2013 | Antimicrob. Agents Chemother. | pmid:23274667 |
James GD et al. | Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. | 2013 | Prim Care Respir J | pmid:23839240 |
Parhi AK et al. | Antibacterial activity of quinoxalines, quinazolines, and 1,5-naphthyridines. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23891185 |
Lee A | Gastroparesis: what is the current state-of-the-art for evaluation and medical management? What are the results? | 2013 | J. Gastrointest. Surg. | pmid:23801519 |
Liu ZX et al. | [Inhibition of methanogenium by erythromycin and its domestation]. | 2013 | Huan Jing Ke Xue | pmid:23798140 |
Pasquini L et al. | Impact of certain household micropollutants on bacterial behavior. Toxicity tests/study of extracellular polymeric substances in sludge. | 2013 | Sci. Total Environ. | pmid:23827359 |
Malinka W et al. | Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes. | 2013 | Bioorg. Med. Chem. | pmid:23850103 |
Sundermann U et al. | Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. | 2013 | ACS Chem. Biol. | pmid:23181268 |
Weber JM et al. | Biotransformation and recovery of the isoflavones genistein and daidzein from industrial antibiotic fermentations. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23604533 |
Yang X et al. | Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China. | 2013 | Environ Sci Pollut Res Int | pmid:23608973 |
Chen Y et al. | Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. | 2013 | Bioprocess Biosyst Eng | pmid:23361182 |
Melnik BC and Schmitz G | Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1? | 2013 | Exp. Dermatol. | pmid:23800068 |
Wittwer MB et al. | Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. | 2013 | J. Med. Chem. | pmid:23241029 |
Gao X et al. | Total synthesis of 6-deoxyerythronolide B via C-C bond-forming transfer hydrogenation. | 2013 | J. Am. Chem. Soc. | pmid:23464668 |
Sánchez Valenzuela A et al. | Phenotypic and molecular antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium isolated from different traditional fermented foods. | 2013 | Foodborne Pathog. Dis. | pmid:23259502 |
Sanad YM et al. | Molecular epidemiology and public health relevance of Campylobacter isolated from dairy cattle and European starlings in Ohio, USA. | 2013 | Foodborne Pathog. Dis. | pmid:23259503 |
Haruna M et al. | Prevalence and antimicrobial resistance of Campylobacter isolates from beef cattle and pigs in Japan. | 2013 | J. Vet. Med. Sci. | pmid:23220905 |
Javid FA et al. | Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors. | 2013 | Eur. J. Pharmacol. | pmid:23201066 |
Goodman CD et al. | Chemobiosynthesis of new antimalarial macrolides. | 2013 | Antimicrob. Agents Chemother. | pmid:23208707 |
Li X et al. | Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. | 2013 | Eur J Med Chem | pmid:23229056 |
Nunez-Samudio V and Chesneau O | Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. | 2013 | Res. Microbiol. | pmid:23261969 |
Secka O et al. | Antimicrobial susceptibility and resistance patterns among Helicobacter pylori strains from The Gambia, West Africa. | 2013 | Antimicrob. Agents Chemother. | pmid:23263004 |
Rożynek E et al. | Emergence of macrolide-resistant Campylobacter strains in chicken meat in Poland and the resistance mechanisms involved. | 2013 | Foodborne Pathog. Dis. | pmid:23638847 |
Dubey D et al. | A report on infection dynamics of inducible clindamycin resistance of Staphylococcus aureus isolated from a teaching hospital in India. | 2013 | Asian Pac J Trop Biomed | pmid:23593595 |
Metzler K et al. | Minimal inhibitory and mutant prevention concentrations of azithromycin, clarithromycin and erythromycin for clinical isolates of Streptococcus pneumoniae. | 2013 | J. Antimicrob. Chemother. | pmid:23169894 |