erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kozak PP et al. | Administration of erythromycin to patients on theophylline. | 1977 | J. Allergy Clin. Immunol. | pmid:874213 |
Ohba M et al. | Effect of clarithromycin on the bioavailability of cyclosporin in rats. | 1996 | Biol. Pharm. Bull. | pmid:8741585 |
Hoppe JE | Update of epidemiology, diagnosis, and treatment of pertussis. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8740851 |
Ripoll L et al. | Interaction of macrolides with alpha dornase during DNA hydrolysis. | 1996 | J. Antimicrob. Chemother. | pmid:8737148 |
Aubier M et al. | Sparfloxacin for the treatment of community-acquired pneumonia: a pooled data analysis of two studies. | 1996 | J. Antimicrob. Chemother. | pmid:8737127 |
Gómez-Lechón MJ et al. | Evidence of antibodies to erythromycin in serum of a patient following an episode of acute drug-induced hepatitis. | 1996 | Clin. Exp. Allergy | pmid:8735873 |
Shinkai I and Ohta Y | New drugs--reports of new drugs recently approved by the FDA. Dirithromycin. | 1996 | Bioorg. Med. Chem. | pmid:8735838 |
Box SA and Lee MR | A systemic reaction following exposure to a pyrethroid insecticide. | 1996 | Hum Exp Toxicol | pmid:8735461 |
Moore JE et al. | Erythromycin-resistant thermophilic Campylobacter species isolated from pigs. | 1996 | Vet. Rec. | pmid:8730692 |
Lopes Cardoso FL et al. | Rhodococcus equi mastoiditis in a patient with AIDS. | 1996 | Clin. Infect. Dis. | pmid:8729214 |
Brouqui P et al. | Eucaryotic cells protect Borrelia burgdorferi from the action of penicillin and ceftriaxone but not from the action of doxycycline and erythromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8726038 |
Fujii T et al. | Inhibitory effect of erythromycin on interleukin 8 production by 1 alpha,25-dihydroxyvitamin D3-stimulated THP-1 cells. | 1996 | Antimicrob. Agents Chemother. | pmid:8726037 |
Champney WS and Burdine R | 50S ribosomal subunit synthesis and translation are equivalent targets for erythromycin inhibition in Staphylococcus aureus. | 1996 | Antimicrob. Agents Chemother. | pmid:8723490 |
van Hoogdalem EJ et al. | Evaluation of the effect of zinc acetate on the stratum corneum penetration kinetics of erythromycin in healthy male volunteers. | 1996 | Skin Pharmacol. | pmid:8722604 |
Hall G et al. | Elimination of bacteraemia after dental extraction: comparison of erythromycin and clindamycin for prophylaxis of infective endocarditis. | 1996 | J. Antimicrob. Chemother. | pmid:8722544 |
Khan MA et al. | A reverse transcriptase-PCR based assay for in-vitro antibiotic susceptibility testing of Chlamydia pneumoniae. | 1996 | J. Antimicrob. Chemother. | pmid:8722533 |
Zimmermann T et al. | Influence of the antibiotics erythromycin and azithromycin on the pharmacokinetics and pharmacodynamics of midazolam. | 1996 | Arzneimittelforschung | pmid:8720318 |
Altrichter T and Heizmann WR | [Gardnerella vaginalis: transport, microscopy, testing resistance]. | 1994 | Geburtshilfe Frauenheilkd | pmid:8719002 |
Ferraro AL et al. | The antimicrobial susceptibility of Streptococcus pyogenes isolates from the Philadelphia area. | 1995 | Adv. Exp. Med. Biol. | pmid:8718607 |
Mortensen JE and McDowell T | Streptococcus pyogenes: resistant, tolerant, neither or both? | 1995 | Adv. Exp. Med. Biol. | pmid:8718606 |
Orden B et al. | [Antibiotic resistance to erythromycin, clindamycin and tetracycline of 573 strains of Streptococcus pyogenes (1992-1994)]. | 1996 | Enferm. Infecc. Microbiol. Clin. | pmid:8714154 |
Tateishi T et al. | Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation. | 1996 | Anesth. Analg. | pmid:8712396 |
Chattopadhyay S et al. | Reactivation of denatured proteins by 23S ribosomal RNA: role of domain V. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8710862 |
Vanderhoof JA et al. | Treatment of cyclic vomiting in childhood with erythromycin. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:8708873 |
Nichterlein T et al. | RP 59500, a streptogramin derivative, is effective in murine listeriosis. | 1996 | J Chemother | pmid:8708741 |
Arranz-Caso JA et al. | Prolonged colonic pseudo-obstruction (Ogilvie syndrome) in an older woman resolved with conservative treatment. | 1996 | J Am Geriatr Soc | pmid:8708296 |
Paz HL et al. | Motility agents for the placement of weighted and unweighted feeding tubes in critically ill patients. | 1996 | Intensive Care Med | pmid:8708166 |
Zanetti S et al. | In-vitro activity of 3-azinomethyl-rifamycin (SPA-S-565) against Chlamydia trachomatis. | 1996 | J. Antimicrob. Chemother. | pmid:8707747 |
Higgins SP | Chlamydial infection in women. | 1996 | Br J Gen Pract | pmid:8703535 |
RamÃrez RamÃrez CR et al. | Bacillary angiomatosis: microbiology, histopathology, clinical presentation, diagnosis and management. | 1995 Jul-Sep | Bol Asoc Med P R | pmid:8703269 |
McBride MJ and Baker SA | Development of techniques to genetically manipulate members of the genera Cytophaga, Flavobacterium, Flexibacter, and Sporocytophaga. | 1996 | Appl. Environ. Microbiol. | pmid:8702294 |
Wasteson Y et al. | Characterization of tetracycline and erythromycin resistance in Actinobacillus pleuropneumoniae. | 1996 | Vet. Microbiol. | pmid:8701576 |
Cadisch R et al. | [Exacerbation of pseudoparalytic myasthenia gravis following azithromycin (Zithromax)]. | 1996 | Schweiz Med Wochenschr | pmid:8701248 |
Koizumi A et al. | [Effect of prolonged administration of erythromycin on the drug sensitivity and the biological properties of Streptococcus pneumoniae]. | 1996 | Kansenshogaku Zasshi | pmid:8699091 |
Horowitz MS and Smith LG | Vegetative bacterial endocarditis on the prolapsing mitral valve. Echocardiographic evaluation. | 1977 | Arch. Intern. Med. | pmid:869651 |
Hall JE and Harmer M | Erythromycin as a prokinetic agent in children. | 1996 | Anaesthesia | pmid:8694177 |
Sanchez MA and Rorat E | Fine needle aspiration diagnosis of intramuscular bacillary angiomatosis. A case report. | 1996 Jul-Aug | Acta Cytol. | pmid:8693899 |
Bailey DG et al. | Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice. | 1996 | Clin. Pharmacol. Ther. | pmid:8689808 |
Matschiner S et al. | Optimization of topical erythromycin formulations by ion pairing. | 1995 | Skin Pharmacol. | pmid:8688198 |
Burgin S and Spencer DC | Bacillary angiomatosis--another South African case. | 1996 | S. Afr. Med. J. | pmid:8685799 |
Edelman K et al. | Detection of Bordetella pertussis by polymerase chain reaction and culture in the nasopharynx of erythromycin-treated infants with pertussis. | 1996 | Pediatr. Infect. Dis. J. | pmid:8684877 |
El-Chaar GM et al. | Randomized, double blind comparison of brand and generic antibiotic suspensions: II. A study of taste and compliance in children. | 1996 | Pediatr. Infect. Dis. J. | pmid:8684871 |
Samulak KM et al. | Randomized, double blind comparison of brand and generic antibiotic suspensions: I. A study of taste in adults. | 1996 | Pediatr. Infect. Dis. J. | pmid:8684870 |
Faghih R et al. | Synthesis and antibacterial activity of 6-deoxysporeamicin A. | 1996 | J. Antibiot. | pmid:8682729 |
Griesgraber G et al. | 3-Keto-11,12-carbazate derivatives of 6-O-methylerythromycin A synthesis and in vitro activity. | 1996 | J. Antibiot. | pmid:8682724 |
Davies JS and Penfold JB | Campylobacter urinary infection. | 1979 | Lancet | pmid:86820 |
Backström M and Kuusela AL | [Unilateral pulmonary edema in an infant]. | 1995 | Duodecim | pmid:8681845 |
Sturm A et al. | [Treatment of radiotherapy-induced gastroparesis with erythromycin]. | 1996 | Dtsch. Med. Wochenschr. | pmid:8681733 |
Coulter WA et al. | Dental anxiety and the absorption of orally administered erythromycin stearate. | 1995 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:8680971 |
Rowbury RJ et al. | Sensitization to acid induced by sodium ions in Escherichia coli: dependence of (p)ppGpp and cAMP and suppression of the relA-associated defect by mutations in envZ. | 1996 | Microbios | pmid:8676748 |