erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Dubois J and St-Pierre C | In vitro susceptibility study of BMS-284756 against Legionella species. | 2001 Sep-Oct | Diagn. Microbiol. Infect. Dis. | pmid:11687318 |
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Gorrini M et al. | Inhibition of human neutrophil elastase by erythromycin and flurythromycin, two macrolide antibiotics. | 2001 | Am. J. Respir. Cell Mol. Biol. | pmid:11694455 |
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Gonorrhea: recommended treatment schedules-1974. Part II: Disseminated gonococcal infection and gonococcal infection in pediatric patients. | 1975 | Obstet Gynecol | pmid:1170528 | |
Koh TW | Risk of torsades de pointes from oral erythromycin with concomitant carbimazole (methimazole) administration. | 2001 | Pacing Clin Electrophysiol | pmid:11707056 |
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Bührer C et al. | Role of erythromycin for treatment of incipient chronic lung disease in preterm infants colonised with Ureaplasma urealyticum. | 2001 | Drugs | pmid:11708762 |
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Ma Z et al. | Novel erythromycin derivatives with aryl groups tethered to the C-6 position are potent protein synthesis inhibitors and active against multidrug-resistant respiratory pathogens. | 2001 | J. Med. Chem. | pmid:11708916 |
Teng LJ et al. | High prevalence of inducible erythromycin resistance among Streptococcus bovis isolates in Taiwan. | 2001 | Antimicrob. Agents Chemother. | pmid:11709309 |
de Azavedo JC et al. | Prevalence and mechanisms of macrolide resistance in invasive and noninvasive group B streptococcus isolates from Ontario, Canada. | 2001 | Antimicrob. Agents Chemother. | pmid:11709331 |
Neuhauser MM et al. | Postantibiotic effects of ABT-773 and amoxicillin-clavulanate against Streptococcus pneumoniae and Haemophilus influenzae. | 2001 | Antimicrob. Agents Chemother. | pmid:11709352 |
Singh KV et al. | In vitro activities of a new ketolide, ABT-773, against multidrug-resistant gram-positive cocci. | 2001 | Antimicrob. Agents Chemother. | pmid:11709359 |
von Kobyletzki G et al. | [Acute generalized cat scratch disease in myelodysplastic syndrome]. | 2001 | Hautarzt | pmid:11715399 |
Ye Y et al. | [Clinic intervention study on urogenital mycoplasma infection of pregnant women]. | 2001 | Zhonghua Liu Xing Bing Xue Za Zhi | pmid:11718071 |
Schmidt LE et al. | Early postoperative erythromycin breath test correlates with hepatic cytochrome P4503A activity in liver transplant recipients. | 2001 | Clin. Pharmacol. Ther. | pmid:11719731 |