erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Padovan J et al. | Investigating the barriers to bioavailability of macrolide antibiotics in the rat. | 2012 | Eur J Drug Metab Pharmacokinet | pmid:22113743 |
| Mokhber-Dezfooli MR et al. | Effect of abomasal emptying rate on the apparent efficiency of colostral immunoglobulin G absorption in neonatal Holstein-Friesian calves. | 2012 | J. Dairy Sci. | pmid:22981576 |
| Walkey AJ and Wiener RS | Macrolide antibiotics and survival in patients with acute lung injury. | 2012 | Chest | pmid:22116799 |
| Wills RH et al. | Structural characterization of polyketides using high mass accuracy tandem mass spectrometry. | 2012 | Anal. Chem. | pmid:22985101 |
| Sugimoto T et al. | Synthesis and structure-activity relationship of a novel class of 15-membered macrolide antibiotics known as '11a-azalides'. | 2012 | Bioorg. Med. Chem. | pmid:22925450 |
| Sugimoto T et al. | Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22858102 |
| Zou MX et al. | Antimicrobial resistance and molecular epidemiological characteristics of clinical isolates of Staphylococcus aureus in Changsha area. | 2012 | Chin. Med. J. | pmid:22882850 |
| Wang L et al. | Persistence of resistance to erythromycin and tetracycline in swine manure during simulated composting and lagoon treatments. | 2012 | Microb. Ecol. | pmid:21811793 |
| Oo C and Shah B | Does erythromycin have anti-inflammatory effects independent of its antimicrobial action? | 2012 | J Clin Pharmacol | pmid:21868717 |
| März A et al. | Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic. | 2012 | Anal Bioanal Chem | pmid:21822777 |
| Tran TD et al. | Synthesis and anti Methicillin resistant Staphylococcus aureus activity of substituted chalcones alone and in combination with non-beta-lactam antibiotics. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22727643 |
| Sommerfeld Ross S and Fiegel J | Nutrient dispersion enhances conventional antibiotic activity against Pseudomonas aeruginosa biofilms. | 2012 | Int. J. Antimicrob. Agents | pmid:22727773 |
| Zaknoon F et al. | Antibacterial properties of an oligo-acyl-lysyl hexamer targeting Gram-negative species. | 2012 | Antimicrob. Agents Chemother. | pmid:22751534 |
| Gant CM et al. | Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22751535 |
| Kim J et al. | Copper resistance and its relationship to erythromycin resistance in Enterococcus isolates from bovine milk samples in Korea. | 2012 | J. Microbiol. | pmid:22752920 |
| Arakawa K et al. | The butenolide signaling molecules SRB1 and SRB2 induce lankacidin and lankamycin production in Streptomyces rochei. | 2012 | Chembiochem | pmid:22761035 |
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| Gazzola S et al. | Assessment of tetracycline and erythromycin resistance transfer during sausage fermentation by culture-dependent and -independent methods. | 2012 | Food Microbiol. | pmid:22365347 |
| Palumbo Piccionello A et al. | Synthesis and preliminary antibacterial evaluation of Linezolid-like 1,2,4-oxadiazole derivatives. | 2012 | Eur J Med Chem | pmid:22365410 |
| Pešić D et al. | Design, synthesis, and in vitro activity of novel 2'-O-substituted 15-membered azalides. | 2012 | J. Med. Chem. | pmid:22380766 |
| Shore EM and Yudin MH | Choice of antibiotic for group B streptococcus in women in labour based on antibiotic sensitivity testing. | 2012 | J Obstet Gynaecol Can | pmid:22385665 |
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| Calcium channel blockers + macrolides: elderly patients hospitalised for low blood pressure. | 2012 | Prescrire Int | pmid:22852287 | |
| Pinto A et al. | 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. | 2012 | Org. Lett. | pmid:22519860 |
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| Deane AM et al. | Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. | 2012 | Am. J. Clin. Nutr. | pmid:22572649 |
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| Rocco L et al. | Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. | 2012 | Environ. Toxicol. | pmid:21384490 |
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| Chen X et al. | Synthesis and antibacterial activity of novel modified 5-O-desosamine ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:23122862 |
| Izumikawa M et al. | JBIR-78 and JBIR-95: phenylacetylated peptides isolated from Kibdelosporangium sp. AK-AA56. | 2012 | J. Nat. Prod. | pmid:22264203 |
| Li M et al. | Effect of erythromycin on cigarette-induced histone deacetylase protein expression and nuclear factor-κB activity in human macrophages in vitro. | 2012 | Int. Immunopharmacol. | pmid:22265969 |
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| Tolosa L et al. | Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. | 2012 | Toxicol. Sci. | pmid:22331495 |
| Ocular prophylaxis for gonococcal ophthalmia neonatorum: reaffirmation recommendation statement. | 2012 | Am Fam Physician | pmid:22335221 |