erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Abdel Fattah NS and Darwish YW | Antibiogram testing of pediatric skin infections in the era of methicillin-resistant Staphylococci aureus: an Egyptian University Hospital-based study. | 2012 | Int. J. Dermatol. | pmid:22928620 |
Kjeldgaard J et al. | Residual antibiotics disrupt meat fermentation and increase risk of infection. | 2012 | MBio | pmid:22930338 |
Krasniqi S et al. | Blood, tissue, and intracellular concentrations of erythromycin and its metabolite anhydroerythromycin during and after therapy. | 2012 | Antimicrob. Agents Chemother. | pmid:22083477 |
Nimgaonkar A et al. | Gastrointestinal dysmotility. | 2012 | Dig. Dis. Sci. | pmid:22038542 |
Kumar R et al. | Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22153939 |
Reutenauer-Patte J et al. | Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways. | 2012 | Am. J. Pathol. | pmid:22192627 |
Romøren M et al. | Pregnancy outcome after gestational exposure to erythromycin - a population-based register study from Norway. | 2012 | Br J Clin Pharmacol | pmid:22463376 |
Lee CH et al. | Case-crossover design: an alternative strategy for detecting drug-induced liver injury. | 2012 | J Clin Epidemiol | pmid:22445086 |
Blode H et al. | Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. | 2012 | Contraception | pmid:22445438 |
Constable PD et al. | Evidence-based use of prokinetic drugs for abomasal disorders in cattle. | 2012 | Vet. Clin. North Am. Food Anim. Pract. | pmid:22374117 |
Mehra T et al. | Treatment of severe acne with low-dose isotretinoin. | 2012 | Acta Derm. Venereol. | pmid:22377969 |
Ogawa W et al. | Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. | 2012 | Gene | pmid:22391093 |
El-Adawy H et al. | Determination of antimicrobial sensitivities of Campylobacter jejuni isolated from commercial turkey farms in Germany. | 2012 | Avian Dis. | pmid:23397839 |
Mercer BM et al. | The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes. | 2012 | Am. J. Obstet. Gynecol. | pmid:22000668 |
Pendela M et al. | Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation. | 2012 | Anal Bioanal Chem | pmid:22002558 |
Wilson BB et al. | An atypical presentation of erythrasma. | 2012 | J. Am. Acad. Dermatol. | pmid:23062922 |
Zhou L et al. | Molecular characteristics of erythromycin-resistant Streptococcus pneumoniae from pediatric patients younger than five years in Beijing, 2010. | 2012 | BMC Microbiol. | pmid:23043378 |
Cannon JA et al. | Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections. | 2012 | Dis. Colon Rectum | pmid:23044677 |
Kaul M et al. | A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization. | 2012 | J. Med. Chem. | pmid:23050700 |
Weisman LE et al. | Appropriate antibiotic therapy improves Ureaplasma sepsis outcome in the neonatal mouse. | 2012 | Pediatr. Res. | pmid:22907617 |
Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
Ezhova NM et al. | [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. | 2011 Nov-Dec | Prikl. Biokhim. Mikrobiol. | pmid:22288199 |
Ridley EJ and Davies AR | Practicalities of nutrition support in the intensive care unit: the usefulness of gastric residual volume and prokinetic agents with enteral nutrition. | 2011 | Nutrition | pmid:21295944 |
Nguyen NQ et al. | Plasma erythromycin concentrations predict feeding outcomes in critically ill patients with feed intolerance. | 2011 | Crit. Care Med. | pmid:21297459 |
Thenmozhi R et al. | Characterization of biofilms in different clinical M serotypes of Streptococcus pyogenes. | 2011 | J. Basic Microbiol. | pmid:21298675 |
Vadlapatla RK et al. | Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin. | 2011 | Int J Pharm | pmid:21864659 |
Lubell Y et al. | Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. | 2011 | Trop. Med. Int. Health | pmid:21740488 |
Spigaglia P et al. | Multidrug resistance in European Clostridium difficile clinical isolates. | 2011 | J. Antimicrob. Chemother. | pmid:21771851 |
Lee HY et al. | Improved precursor-directed biosynthesis in E. coli via directed evolution. | 2011 | J. Antibiot. | pmid:21081955 |
Drago L et al. | Macrolide resistance and in vitro selection of resistance to antibiotics in Lactobacillus isolates. | 2011 | J. Microbiol. | pmid:21887650 |
Liu K et al. | Direct entry to erythronolides via a cyclic bis[allene]. | 2011 | J. Am. Chem. Soc. | pmid:21894913 |
Bonofiglio L et al. | Dissemination of an erythromycin-resistant penicillin-nonsusceptible Streptococcus pneumoniae Poland(6B)-20 clone in Argentina. | 2011 | Microb. Drug Resist. | pmid:21128835 |
Zanoni RG et al. | Occurrence of Helicobacter pullorum in turkeys. | 2011 | Vet. Microbiol. | pmid:21144678 |
Altraif I et al. | Effect of erythromycin before endoscopy in patients presenting with variceal bleeding: a prospective, randomized, double-blind, placebo-controlled trial. | 2011 | Gastrointest. Endosc. | pmid:21145052 |
Taillon MP et al. | Potentially new isobaric metabolite of fluvastatin observed by LC-MS/MS during incurred sample analysis. | 2011 | Bioanalysis | pmid:21877892 |
Koulnis M et al. | Negative autoregulation by Fas stabilizes adult erythropoiesis and accelerates its stress response. | 2011 | PLoS ONE | pmid:21760888 |
Luo DQ et al. | In vitro activities of erythromycin, tetracycline and levofloxacin alone and in dual combinations against ureaplasma spp. | 2011 | Chemotherapy | pmid:21430380 |
Yongsheng J et al. | Antitumor activity of erythromycin on human neuroblastoma cell line (SH-SY5Y). | 2011 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:21336720 |
Pérez-Trallero E et al. | In vitro activities of retapamulin and 16 other antimicrobial agents against recently obtained Streptococcus pyogenes isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:21343452 |
Filić D et al. | Crystal structure and physicochemical properties of crystalline form of 2'-O-{3-[(7-chloro-4-quinolinyl)amino]propyl}-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A. | 2011 | J Pharm Sci | pmid:21394721 |
Wu JC and Sung JJ | Pharmacologic therapy for nonvariceal upper gastrointestinal bleeding. | 2011 | Gastrointest. Endosc. Clin. N. Am. | pmid:21944417 |
Kovacs TO and Jensen DM | Endoscopic therapy for severe ulcer bleeding. | 2011 | Gastrointest. Endosc. Clin. N. Am. | pmid:21944418 |
Ozkok IP et al. | Respirometric assessment of substrate binding by antibiotics in peptone biodegradation. | 2011 | J Environ Sci Health A Tox Hazard Subst Environ Eng | pmid:22029701 |
Justa RF et al. | Bacillary angiomatosis in HIV-positive patient from Northeastern Brazil: a case report. | 2011 | Rev. Soc. Bras. Med. Trop. | pmid:22031085 |
Ma X and Ma S | Significant breakthroughs in search for anti-infectious agents derived from erythromycin A. | 2011 | Curr. Med. Chem. | pmid:21517774 |
Boecxstaens V et al. | Modulation of the postprandial acid and bile pockets at the gastro-oesophageal junction by drugs that affect gastric motility. | 2011 | Aliment. Pharmacol. Ther. | pmid:21517922 |
Sugawara A et al. | Novel 12-membered non-antibiotic macrolides from erythromycin A; EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21524580 |
Cong C et al. | Synthesis and antibacterial activity of novel 4″-O-benzimidazolyl clarithromycin derivatives. | 2011 | Eur J Med Chem | pmid:21524827 |
Ando F et al. | Synergic effects of β-estradiol and erythromycin on hERG currents. | 2011 | J. Membr. Biol. | pmid:21484263 |
Bansal BK et al. | Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health. | 2011 | Trop Anim Health Prod | pmid:20844949 |