erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Chen J et al. | [An experimental study on the effect of azithromycin treatment in bleomycin-induced pulmonary fibrosis of rats]. | 1999 | Zhonghua Nei Ke Za Zhi | pmid:11798706 |
| Abouesh A et al. | Antimicrobial-induced mania (antibiomania): a review of spontaneous reports. | 2002 | J Clin Psychopharmacol | pmid:11799346 |
| Rollins G | Single antibiotic therapy as effective as dual in treating patients hospitalized with community acquired pneumonia. | 2000 | Rep Med Guidel Outcomes Res | pmid:11799995 |
| Cid A et al. | Recurrent bacteremia caused by Rhodococcus equi in a non-neutropenic patient with acute myeloid leukemia in complete remission. | 2002 | Haematologica | pmid:11801477 |
| Xu Z et al. | [Effects of erythromycin and fosfomycin on Pseudomonas aeruginosa biofilm in vitro]. | 2001 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11802985 |
| Belizhenko GG | [Effect of trypsin on the activity of tetracycline, erythromycin and levomycetin]. | 1975 | Antibiotiki | pmid:1180534 |
| Kamagate A et al. | [A comparative study of various evaluation methods of the antibiotic sensitivity of strict anaerobic bacteria of the subgingival flora]. | 2001 | Odontostomatol Trop | pmid:11808376 |
| Basak PY et al. | The effect of benzoyl peroxide and benzoyl peroxide/erythromycin combination on the antioxidative defence system in papulopustular acne. | 2002 Jan-Feb | Eur J Dermatol | pmid:11809596 |
| Tateda K et al. | Potential of macrolide antibiotics to inhibit protein synthesis of Pseudomonas aeruginosa: suppression of virulence factors and stress response. | 2000 | J. Infect. Chemother. | pmid:11810524 |
| Mitsuya Y et al. | Influence of macrolides on guanosine diphospho-D-mannose dehydrogenase activity in Pseudomonas biofilm. | 2000 | J. Infect. Chemother. | pmid:11810531 |
| Li M et al. | In-vitro and in-vivo antibiotic susceptibilities of Lyme disease Borrelia isolated in China. | 2000 | J. Infect. Chemother. | pmid:11810535 |
| Lee K et al. | Trends in serotypes and antimicrobial susceptibility of group B streptococci isolated in Korea. | 2000 | J. Infect. Chemother. | pmid:11810542 |
| Kunishima H et al. | Evaluation of the activity of antimicrobial agents against Legionella pneumophila multiplying in a human monocytic cell line, THP-1, and an alveolar epithelial cell line, A549. | 2000 | J. Infect. Chemother. | pmid:11810567 |
| Tan W et al. | [The mechanism and effect of erythromycin in development of pulmonary fibrosis]. | 1999 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11812357 |
| Depoortere I | Motilin and motilin receptors: characterization and functional significance. | 2001 | Verh. K. Acad. Geneeskd. Belg. | pmid:11813507 |
| Vorbach H et al. | Endothelial cell compatibility of azithromycin and erythromycin. | 2002 | J. Antimicrob. Chemother. | pmid:11815590 |
| Bradley C | Erythromycin as a gastrointestinal prokinetic agent. | 2001 | Intensive Crit Care Nurs | pmid:11817442 |
| Xuan D et al. | Pharmacokinetics of ABT-773, a new semi-synthetic ketolide in neutropenic lung-infected mice: a population approach. | 2002 | J. Pharm. Pharmacol. | pmid:11829132 |
| Visudhiphan P and Chiemchanya S | Mima polymorpha ventriculitis in a young infant. Problems in overcoming the infection with erythromycin intraventricularly. | 1975 | Clin Pediatr (Phila) | pmid:1183131 |
| Weitnauer G et al. | Analysis of a C-methyltransferase gene (aviG1) involved in avilamycin biosynthesis in Streptomyces viridochromogenes Tü57 and complementation of a Saccharopolyspora erythraea eryBIII mutant by aviG1. | 2002 | Microbiology (Reading, Engl.) | pmid:11832501 |
| Goodchild C et al. | Antimicrobial susceptibility of Campylobacter species. | 2001 | N. Z. Med. J. | pmid:11833968 |
| Edder P et al. | Analysis of erythromycin and oleandomycin residues in food by high-performance liquid chromatography with fluorometric detection. | 2002 | Food Addit Contam | pmid:11834075 |
| Krishnan P et al. | Diffuse panbronchiolitis: a treatable sinobronchial disease in need of recognition in the United States. | 2002 | Chest | pmid:11834689 |
| Kawakami K et al. | Assessment of amorphous content by microcalorimetry. | 2002 | J Pharm Sci | pmid:11835201 |
| Gaylor AS and Reilly JC | Therapy with macrolides in patients with cystic fibrosis. | 2002 | Pharmacotherapy | pmid:11837560 |
| Petrakis IE et al. | Hyperglycemia attenuates erythromycin-induced acceleration of liquid-phase gastric emptying of hypertonic liquids in healthy subjects. | 2002 | Dig. Dis. Sci. | pmid:11837735 |
| Cane DE et al. | Precursor-directed biosynthesis: biochemical basis of the remarkable selectivity of the erythromycin polyketide synthase toward unsaturated triketides. | 2002 | Chem. Biol. | pmid:11841945 |
| Nieto JE et al. | Use of an extracorporeal circuit to evaluate effects of intraluminal distention and decompression on the equine jejunum. | 2002 | Am. J. Vet. Res. | pmid:11843129 |
| LeMahieu RA et al. | A facile preparation or erythronolide A oxime. | 1975 | J. Antibiot. | pmid:1184479 |
| Mizukane R et al. | An elderly patient with hemophagocytic syndrome due to severe mycoplasma pneumonia with marked hypercytokinemia. | 2002 | Respiration | pmid:11844970 |
| Speciale A et al. | Minimal inhibitory concentrations and time-kill determination of moxifloxacin against aerobic and anaerobic isolates. | 2002 | Int. J. Antimicrob. Agents | pmid:11850163 |
| Shortridge VD et al. | Comparison of in vitro activities of ABT-773 and telithromycin against macrolide-susceptible and -resistant streptococci and staphylococci. | 2002 | Antimicrob. Agents Chemother. | pmid:11850262 |
| McDermott JS et al. | Importance of species selection in arrythmogenic models of Q-T interval prolongation. | 2002 | Antimicrob. Agents Chemother. | pmid:11850295 |
| Uh Y et al. | Penicillin-resistant Aerococcus viridans bacteremia associated with granulocytopenia. | 2002 | J. Korean Med. Sci. | pmid:11850599 |
| Swart EL et al. | Correlation between midazolam and lignocaine pharmacokinetics and MEGX formation in healthy volunteers. | 2002 | Br J Clin Pharmacol | pmid:11851636 |
| Louik C et al. | Erythromycin use during pregnancy in relation to pyloric stenosis. | 2002 | Am. J. Obstet. Gynecol. | pmid:11854652 |
| RodrÃguez-Avial I et al. | [In vitro activity of six fluoroquinolones and penicillin against 101 viridans group streptococci characterized by their susceptibility to erythromycin]. | 2001 | Rev Esp Quimioter | pmid:11856983 |
| Chou CC and Wu D | Torsade de pointes induced by metoclopramide in an elderly woman with preexisting complete left bundle branch block. | 2001 | Chang Gung Med J | pmid:11858397 |
| Casellas JM et al. | In vitro activity of the new ketolide ABT-773 against community acquired respiratory tract isolates and Viridans Streptococci. | 2002 | Diagn. Microbiol. Infect. Dis. | pmid:11858905 |
| Guchelaar HJ et al. | Pharmacokinetic-pharmacodynamic modeling of the inhibitory effect of erythromycin on tumour necrosis factor-alpha and interleukin-6 production. | 2001 | Fundam Clin Pharmacol | pmid:11860530 |
| Yamakawa T et al. | In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone. | 2002 | J. Antimicrob. Chemother. | pmid:11864945 |
| Karpova GV et al. | Early and delayed effects of carboplatin on the blood system. | 2001 | Bull. Exp. Biol. Med. | pmid:11865323 |
| Lotgering FK et al. | [Erythromycin in premature rupture of membranes beneficial to the health of the child]. | 2002 | Ned Tijdschr Geneeskd | pmid:11865663 |
| Sondheimer JM | A question that won't go away. | 2002 | J. Pediatr. Gastroenterol. Nutr. | pmid:11865812 |
| Zhanel GG and Hoban DJ | Ketolides in the treatment of respiratory infections. | 2002 | Expert Opin Pharmacother | pmid:11866679 |
| Wardell JN et al. | Decreasing the hyphal branching rate of Saccharopolyspora erythraea NRRL 2338 leads to increased resistance to breakage and increased antibiotic production. | 2002 | Biotechnol. Bioeng. | pmid:11870604 |
| Mas MR et al. | Comparison of effects of cholecystokinin and erythromycin on bile chemistry and gallstone formation in aged guinea pigs. | 2002 Jan-Feb | Indian J Gastroenterol | pmid:11871842 |
| Cui M et al. | A density-functional study of the mechanism for the diastereoselective epoxidation of chiral allylic alcohols by the titanium peroxy complexes. | 2002 | J. Org. Chem. | pmid:11871869 |
| Muirhead GJ et al. | The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers. | 2002 | Br J Clin Pharmacol | pmid:11879258 |
| Janowski T et al. | Combined gnRH and PGF2alpha application in cows with endometritis puerperalis treated with antibiotics. | 2001 | Reprod. Domest. Anim. | pmid:11885741 |