erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| San Pedro de Saenz B et al. | FDE to macrolides. | 2002 | Allergy | pmid:11991294 |
| Gaisser S et al. | Parallel pathways for oxidation of 14-membered polyketide macrolactones in Saccharopolyspora erythraea. | 2002 | Mol. Microbiol. | pmid:11994157 |
| Kudelina RI and Olsuf'ev NG | [Further study of the sensitivity to erythromycin of strains of the causative agent of tularemia from different geographical sites]. | 1975 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:1199584 |
| Kato Y et al. | Functional expression of genes involved in the biosynthesis of the novel polyketide chain extension unit, methoxymalonyl-acyl carrier protein, and engineered biosynthesis of 2-desmethyl-2-methoxy-6-deoxyerythronolide B. | 2002 | J. Am. Chem. Soc. | pmid:11996558 |
| Munckhof WJ et al. | Recent appearance of clindamycin resistance in community-acquired methicillin-resistant Staphylococcus aureus (MRSA) in south-east Queensland. | 2002 | Med. J. Aust. | pmid:11999249 |
| Moonmangmee D et al. | L-erythrulose production by oxidative fermentation is catalyzed by PQQ-containing membrane-bound dehydrogenase. | 2002 | Biosci. Biotechnol. Biochem. | pmid:11999403 |
| Coates P et al. | Prevalence of antibiotic-resistant propionibacteria on the skin of acne patients: 10-year surveillance data and snapshot distribution study. | 2002 | Br. J. Dermatol. | pmid:12000382 |
| Champney WS and Miller M | Inhibition of 50S ribosomal subunit assembly in Haemophilus influenzae cells by azithromycin and erythromycin. | 2002 | Curr. Microbiol. | pmid:12000992 |
| Hsueh PR et al. | Increased prevalence of erythromycin resistance in streptococci: substantial upsurge in erythromycin-resistant M phenotype in Streptococcus pyogenes (1979-1998) but not in Streptococcus pneumoniae (1985-1999) in Taiwan. | 2002 | Microb. Drug Resist. | pmid:12002646 |
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| Grignon B et al. | Validation of diffusion methods for macrolide susceptibility testing of Helicobacter pylori. | 2002 | Microb. Drug Resist. | pmid:12002651 |
| Nilius AM et al. | Comparison of selection for mutants with reduced susceptibility to ABT-773, erythromycin and rifampicin in respiratory tract pathogens. | 2002 | J. Antimicrob. Chemother. | pmid:12003979 |
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| Braga PC | Rokitamycin: bacterial resistance to a 16-membered ring macrolide differs from that to 14- and 15-membered ring macrolides. | 2002 | J Chemother | pmid:12017366 |
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| Kim YH et al. | Purification and characterization of an erythromycin esterase from an erythromycin-resistant Pseudomonas sp. | 2002 | FEMS Microbiol. Lett. | pmid:12044681 |
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| Kobayashi Y et al. | Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice. | 2002 | Mol. Pharmacol. | pmid:12065749 |
| Li Y et al. | [Attenuated mRNA induction of molecules associated with neutrophil migration by 14-membered ring macrolides inhibits bleomycin induced acute lung injury in mice]. | 2002 | J Nippon Med Sch | pmid:12068316 |
| Krcmery V et al. | Trends in Streptococcus pyogenes resistance to erythromycin in Slovakia: is there a correlation with consumption? | 2002 | Scand. J. Infect. Dis. | pmid:12069033 |
| Gianneechini RE et al. | Antimicrobial susceptibility of udder pathogens isolated from dairy herds in the west littoral region of Uruguay. | 2002 | Acta Vet. Scand. | pmid:12071114 |
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| Reignier J et al. | Erythromycin and early enteral nutrition in mechanically ventilated patients. | 2002 | Crit. Care Med. | pmid:12072674 |
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| Nishikawa K et al. | Functional characteristics of the pylorus in patients undergoing pylorus--preserving gastrectomy for early gastric cancer. | 2002 | Surgery | pmid:12075173 |
| Cervin A et al. | One-year low-dose erythromycin treatment of persistent chronic sinusitis after sinus surgery: clinical outcome and effects on mucociliary parameters and nasal nitric oxide. | 2002 | Otolaryngol Head Neck Surg | pmid:12075221 |
| Thiboutot D et al. | A randomized, parallel, vehicle-controlled comparison of two erythromycin/benzoyl peroxide preparations for acne vulgaris. | 2002 | Clin Ther | pmid:12075945 |
| Bousquet-Melou A and Toutain PL | Effects of altered plasma alpha1-acid glycoprotein levels on pharmacokinetics of some basic antibiotics in pigs: simulation analysis. | 2002 | J. Vet. Pharmacol. Ther. | pmid:12081621 |
| Pfeifer B et al. | Process and metabolic strategies for improved production of Escherichia coli-derived 6-deoxyerythronolide B. | 2002 | Appl. Environ. Microbiol. | pmid:12089005 |
| DomÃnguez E et al. | Antibiotic resistance in Staphylococcus isolates obtained from fecal samples of healthy children. | 2002 | J. Clin. Microbiol. | pmid:12089295 |
| Cooper WO et al. | Very early exposure to erythromycin and infantile hypertrophic pyloric stenosis. | 2002 | Arch Pediatr Adolesc Med | pmid:12090829 |
| Draelos ZD and Tanghetti EA | Optimizing the use of tazarotene for the treatment of facial acne vulgaris through combination therapy. | 2002 | Cutis | pmid:12095065 |
| von Hunolstein C et al. | Penicillin tolerance amongst non-toxigenic Corynebacterium diphtheriae isolated from cases of pharyngitis. | 2002 | J. Antimicrob. Chemother. | pmid:12096018 |