erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Shang Y et al. | Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis. | 2011 | Chin. Med. J. | pmid:21362305 |
Pateron D et al. | Erythromycin infusion or gastric lavage for upper gastrointestinal bleeding: a multicenter randomized controlled trial. | 2011 | Ann Emerg Med | pmid:21333385 |
Cai XJ et al. | [Protective effects of erythromycin on human bronchial epithelial cells impaired by interleukin-4]. | 2011 | Zhonghua Yi Xue Za Zhi | pmid:22094097 |
Otsu K et al. | Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. | 2011 | Pharmacology | pmid:22116077 |
Zhang L et al. | Synthesis and antibacterial activity of new 4″-O-carbamates of 11,12-cyclic carbonate erythromycin A 6,9-imino ether. | 2011 | J. Antibiot. | pmid:21245870 |
Nielsen EI et al. | Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model. | 2011 | Antimicrob. Agents Chemother. | pmid:21282424 |
Belousoff MJ et al. | Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21282615 |
Spigaglia P et al. | Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. | 2011 | Emerging Infect. Dis. | pmid:21291621 |
Huppertz A et al. | Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor of organic anion transporting peptides (OATP). | 2011 | J Magn Reson Imaging | pmid:21274983 |
Maeda Y et al. | Comparison of minimum inhibitory concentration by broth microdilution testing versus standard disc diffusion testing in the detection of penicillin, erythromycin and ciprofloxacin resistance in viridans group streptococci. | 2011 | J. Med. Microbiol. | pmid:21852527 |
Chen Y et al. | Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions. | 2011 | Drug Metab. Dispos. | pmid:21835977 |
Ahmetagic A et al. | Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. | 2011 | Plasmid | pmid:21839110 |
Zhou L et al. | Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. | 2011 | Vaccine | pmid:21839135 |
Senthilkumaran S and Subramanian PT | Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. | 2011 | Indian Pediatr | pmid:22711153 |
Qin X et al. | Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. | 2011 | Int. J. Antimicrob. Agents | pmid:21549571 |
Sigaroudinia MO and Quayle AR | Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. | 2011 | Surgeon | pmid:21550524 |
Juntunen P et al. | Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. | 2011 | Vet. Microbiol. | pmid:21397412 |
Boghigian BA et al. | Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. | 2011 | J. Ind. Microbiol. Biotechnol. | pmid:21487833 |
Spurling GK et al. | Antibiotics for bronchiolitis in children. | 2011 | Cochrane Database Syst Rev | pmid:21678346 |
Matsson EM et al. | Biliary excretion of ximelagatran and its metabolites and the influence of erythromycin following intraintestinal administration to healthy volunteers. | 2011 | J Clin Pharmacol | pmid:20663994 |
Amachawadi RG et al. | Selection of fecal enterococci exhibiting tcrB-mediated copper resistance in pigs fed diets supplemented with copper. | 2011 | Appl. Environ. Microbiol. | pmid:21705534 |
Tanamachi C et al. | [A case of Desulfovibrio desulfuricans cultured from blood in Japan]. | 2011 | Rinsho Byori | pmid:21706860 |
Mikura S et al. | Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. | 2011 | Transl Res | pmid:21708354 |
Richter SS et al. | Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009. | 2011 | Antimicrob. Agents Chemother. | pmid:21709080 |
Muruganathan G et al. | Interaction study of moxifloxacin and lomefloxacin with co-administered drugs. | 2011 | Pak J Pharm Sci | pmid:21715267 |
Lobanov KV et al. | Reconstruction of Purine Metabolism in Bacillus subtilis to Obtain the Strain Producer of AICAR: A New Drug with a Wide Range of Therapeutic Applications. | 2011 | Acta Naturae | pmid:22649686 |
Aknin LB et al. | It's the recipient that counts: spending money on strong social ties leads to greater happiness than spending on weak social ties. | 2011 | PLoS ONE | pmid:21347326 |
Manneck T et al. | Schistosoma mansoni: antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo. | 2011 | Exp. Parasitol. | pmid:20732321 |
Wang SM et al. | Clinical significance of erythromycin-resistant Campylobacter jejuni in children. | 2011 | J Microbiol Immunol Infect | pmid:21531355 |
Dinh QT et al. | Measurement of trace levels of antibiotics in river water using on-line enrichment and triple-quadrupole LC-MS/MS. | 2011 | Talanta | pmid:21807177 |
Pignatello R et al. | Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. | 2011 | AAPS PharmSciTech | pmid:21479751 |
Keelan JA et al. | Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. | 2011 | Am. J. Obstet. Gynecol. | pmid:21481833 |
Fan C and He J | Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. | 2011 | Water Res. | pmid:21482429 |
Franke RM et al. | Effect of ABCC2 (MRP2) transport function on erythromycin metabolism. | 2011 | Clin. Pharmacol. Ther. | pmid:21451505 |
Li Y et al. | Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. | 2011 | J. Appl. Microbiol. | pmid:20961364 |
Vuppalanchi R et al. | Drug-induced QT prolongation in cirrhotic patients with transjugular intrahepatic portosystemic shunt. | 2011 | J. Clin. Gastroenterol. | pmid:20962670 |
Park HH et al. | The effect of macrolides on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. | 2010 Sep-Oct | Am J Rhinol Allergy | pmid:21244734 |
Luiz DB et al. | Identification of degradation products of erythromycin A arising from ozone and advanced oxidation process treatment. | 2010 Sep-Oct | Water Environ. Res. | pmid:20942335 |
Al-Talib HI et al. | Methicillin-resistant Staphylococcus aureus nosocomial infection trends in Hospital Universiti Sains Malaysia during 2002-2007. | 2010 Sep-Oct | Ann Saudi Med | pmid:20697171 |
Murray MA et al. | Ocular bacillary angiomatosis in an immunocompromised man. | 2010 Sep-Oct | Ophthal Plast Reconstr Surg | pmid:20683276 |
Taneja N et al. | Emergence of tetracycline resistance in Vibrio cholerae O1 biotype El Tor serotype Ogawa from north India. | 2010 Oct-Dec | Indian J Pathol Microbiol | pmid:21045454 |
Dutil M | Benzoyl peroxide: enhancing antibiotic efficacy in acne management. | 2010 Nov-Dec | Skin Therapy Lett. | pmid:21076800 |
Levin TT et al. | Case report: delirium due to a diltiazem-fentanyl CYP3A4 drug interaction. | 2010 Nov-Dec | Gen Hosp Psychiatry | pmid:21112467 |
Bornstein E et al. | Photodamage to multidrug-resistant gram-positive and gram-negative bacteria by 870 nm/930 nm light potentiates erythromycin, tetracycline and ciprofloxacin. | 2010 May-Jun | Photochem. Photobiol. | pmid:20408973 |
Taylor SJ et al. | Treating delayed gastric emptying in critical illness: metoclopramide, erythromycin, and bedside (cortrak) nasointestinal tube placement. | 2010 May-Jun | JPEN J Parenter Enteral Nutr | pmid:20467010 |
Zhang LX et al. | Febrile ulceronecrotic Mucha-Habermann's disease with pulmonary involvement. | 2010 May-Jun | Pediatr Dermatol | pmid:20609148 |
Vorster M et al. | Erythromycin as an alternative to reduce interfering extra-cardiac activity in myocardial perfusion imaging. | 2010 May-Jun | Cardiovasc J Afr | pmid:20532452 |
Poulard F et al. | Impact of not measuring residual gastric volume in mechanically ventilated patients receiving early enteral feeding: a prospective before-after study. | 2010 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:19861528 |
Torrelo A et al. | Extensive comedonal and cystic acne in Patau syndrome. | 2010 Mar-Apr | Pediatr Dermatol | pmid:20537076 |
Armangil D et al. | Maternal pertussis is hazardous for a newborn: a case report. | 2010 Mar-Apr | Turk. J. Pediatr. | pmid:20560262 |