erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Namikawa H et al. | Effect of erythromycin A and its new derivative EM201 on type I collagen production by cultured dermal fibroblasts. | 2010 | Arch. Dermatol. Res. | pmid:19578864 |
| He ZY et al. | Effect of 6 months of erythromycin treatment on inflammatory cells in induced sputum and exacerbations in chronic obstructive pulmonary disease. | 2010 | Respiration | pmid:20881376 |
| Liu Y et al. | 9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety. | 2010 | Bioorg. Med. Chem. | pmid:20869254 |
| Leszczyńska K et al. | Modulation of exogenous antibiotic activity by host cathelicidin LL-37. | 2010 | APMIS | pmid:20955455 |
| Atkins JL et al. | Enhancement of antimicrobial activity by synthetic ion channel synergy. | 2010 | Chem. Commun. (Camb.) | pmid:20931142 |
| Keurulainen L et al. | Design and synthesis of 2-arylbenzimidazoles and evaluation of their inhibitory effect against Chlamydia pneumoniae. | 2010 | J. Med. Chem. | pmid:20932010 |
| Dunkle JA et al. | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20876128 |
| van der Beek MT et al. | Inaccuracy of routine susceptibility tests for detection of erythromycin resistance of Campylobacter jejuni and Campylobacter coli. | 2010 | Clin. Microbiol. Infect. | pmid:19438640 |
| Aguilera R C et al. | [Antimicrobial susceptibility, capsular serotypes and clonal relationship of invasive streptococcus pneumoniae isolates in adult population of the Bio-Bio region, Chile. 2005-2006]. | 2010 | Rev Chilena Infectol | pmid:21186502 |
| Cetin ES et al. | Distribution of genes encoding resistance to macrolides, lincosamides and streptogramins among clinical staphylococcal isolates in a Turkish university hospital. | 2010 | J Microbiol Immunol Infect | pmid:21195981 |
| Pazoki-Toroudi H et al. | Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. | 2010 | J Dermatolog Treat | pmid:20394495 |
| Stringer E et al. | Treatment of trichomoniasis in pregnancy in sub-Saharan Africa does not appear to be associated with low birth weight or preterm birth. | 2010 | S. Afr. Med. J. | pmid:20429491 |
| Chandra B et al. | Catalytic asymmetric synthesis of complex polypropionates: Lewis base catalyzed aldol equivalents in the synthesis of erythronolide B. | 2010 | Angew. Chem. Int. Ed. Engl. | pmid:20209542 |
| Yao J et al. | Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. | 2010 | Bioorg. Med. Chem. Lett. | pmid:19959361 |
| Tokuda A et al. | Effects of macrolides on antigen-induced increases in cough reflex sensitivity in guinea pigs. | 2010 | Pulm Pharmacol Ther | pmid:19835975 |
| Padilla E et al. | Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. | 2010 | Antimicrob. Agents Chemother. | pmid:19858254 |
| Glass SK et al. | Canadian province-level risk factor analysis of macrolide consumption patterns (2000-2006). | 2010 | J. Antimicrob. Chemother. | pmid:19864333 |
| Goetting-Minesky MP and Fenno JC | A simplified erythromycin resistance cassette for Treponema denticola mutagenesis. | 2010 | J. Microbiol. Methods | pmid:20691222 |
| Mazzoncini JP et al. | Human metapneumovirus: an emerging respiratory pathogen. | 2010 | J Emerg Med | pmid:18584996 |
| Banche G et al. | Synergistic effect of erythromycin on polymorphonuclear cell antibacterial activity against erythromycin-resistant phenotypes of Streptococcus pyogenes. | 2010 | Int. J. Antimicrob. Agents | pmid:20692129 |
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| Horner P | Chlamydia (uncomplicated, genital). | 2010 | BMJ Clin Evid | pmid:21718568 |
| Ren W et al. | Efficacy of periprosthetic erythromycin delivery for wear debris-induced inflammation and osteolysis. | 2010 | Inflamm. Res. | pmid:20607583 |
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| Kana BD et al. | Depletion of resuscitation-promoting factors has limited impact on the drug susceptibility of Mycobacterium tuberculosis. | 2010 | J. Antimicrob. Chemother. | pmid:20542905 |
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| Gunell M et al. | In vitro activity of azithromycin against nontyphoidal Salmonella enterica. | 2010 | Antimicrob. Agents Chemother. | pmid:20498312 |
| Zähner D et al. | Human antimicrobial peptide LL-37 induces MefE/Mel-mediated macrolide resistance in Streptococcus pneumoniae. | 2010 | Antimicrob. Agents Chemother. | pmid:20498319 |
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| Krenauer A et al. | EBV-associated post-transplantation B-cell lymphoproliferative disorder following allogenic stem cell transplantation for acute lymphoblastic leukaemia: tumor regression after reduction of immunosuppression--a case report. | 2010 | Diagn Pathol | pmid:20356360 |
| Sun H et al. | Hepatic clearance, but not gut availability, of erythromycin is altered in patients with end-stage renal disease. | 2010 | Clin. Pharmacol. Ther. | pmid:20090676 |
| Cousens S et al. | Antibiotics for pre-term pre-labour rupture of membranes: prevention of neonatal deaths due to complications of pre-term birth and infection. | 2010 | Int J Epidemiol | pmid:20348116 |
| Devirgiliis C et al. | Identification of tetracycline- and erythromycin-resistant Gram-positive cocci within the fermenting microflora of an Italian dairy food product. | 2010 | J. Appl. Microbiol. | pmid:20092542 |