erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Zhang W et al. Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. 2011 Curr. Microbiol. pmid:20924584
Hewer RC et al. PKA and Epac synergistically inhibit smooth muscle cell proliferation. 2011 J. Mol. Cell. Cardiol. pmid:20971121
Fessler AT et al. Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. 2011 Antimicrob. Agents Chemother. pmid:20876371
Nakashima R et al. Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. 2011 Nature pmid:22121023
Abarzúa F et al. [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. 2011 Rev Chilena Infectol pmid:22052397
Song W et al. Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. 2011 Int J Nanomedicine pmid:22228990
Hiller NL et al. Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. 2011 PLoS ONE pmid:22205975
Zhang Q et al. Knocking out of tailoring genes eryK and eryG in an industrial erythromycin-producing strain of Saccharopolyspora erythraea leading to overproduction of erythromycin B, C and D at different conversion ratios. 2011 Lett. Appl. Microbiol. pmid:21175699
Lam HS and Ng PC Use of prokinetics in the preterm infant. 2011 Curr. Opin. Pediatr. pmid:21178622
Ma S et al. Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. 2011 Eur J Med Chem pmid:21159410
Raynes Greenow CH et al. Antibiotics for ureaplasma in the vagina in pregnancy. 2011 Cochrane Database Syst Rev pmid:21901685
Wunder DB et al. Sorption of antibiotics to biofilm. 2011 Water Res. pmid:21334040
Wei Z and Wang J Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. 2011 Anal. Chim. Acta pmid:21565301
Ren W and Markel DC Emerging ideas: can erythromycin reduce the risk of aseptic loosening? 2011 Clin. Orthop. Relat. Res. pmid:21584820
Torra S et al. Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). 2011 Int J Obes (Lond) pmid:20938444
Li AP and Doshi U Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. 2011 Drug Metab Lett pmid:21722087
Imperi M et al. Invasive neonatal GBS infections from an area-based surveillance study in Italy. 2011 Clin. Microbiol. Infect. pmid:21722258
Wan G et al. Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. 2011 Cell. Signal. pmid:21723942
Miyashita N et al. Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age. 2011 J. Infect. Chemother. pmid:20676912
Chen I et al. Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. 2011 J. Clin. Microbiol. pmid:21068284
Modali SD and Zgurskaya HI The periplasmic membrane proximal domain of MacA acts as a switch in stimulation of ATP hydrolysis by MacB transporter. 2011 Mol. Microbiol. pmid:21696464
Jorgensen JH et al. Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. 2011 J. Clin. Microbiol. pmid:21697321
Wenzel F et al. Alterations of serum erythropoietin and thrombopoietin levels in patients undergoing Coronary Artery Bypass Grafting (CABG). 2011 Clin. Hemorheol. Microcirc. pmid:22214710
Mansi Y et al. Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants. 2011 Neonatology pmid:21701222
Amarir-Bouhram J et al. Low efficiency of homology-facilitated illegitimate recombination during conjugation in Escherichia coli. 2011 PLoS ONE pmid:22194937
Ng PC Erythromycin as a prokinetic agent in newborns--useful or doubtful. Commentary on Y. Mansi et al.: Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants (Neonatology 2011;100:290-294). 2011 Neonatology pmid:21701224
Sarig H et al. Functional studies of cochleate assemblies of an oligo-acyl-lysyl with lipid mixtures for combating bacterial multidrug resistance. 2011 FASEB J. pmid:21676947
Boghigian BA et al. Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. 2011 Biotechnol. Bioeng. pmid:21337322
Kataoka M et al. Estimation of P-glycoprotein-mediated efflux in the oral absorption of P-gp substrate drugs from simultaneous analysis of drug dissolution and permeation. 2011 Eur J Pharm Sci pmid:21963456
Hernández y Ballinas A et al. [Comparison of maternal and perinatal outcomes in the conservative treatment preterm premature membrane rupture between the use of erythromycin and clindamycin]. 2011 Ginecol Obstet Mex pmid:21966834
Gupta R et al. A 14-year-old with rectal bleeding and abdominal pain. 2011 J. Pediatr. Gastroenterol. Nutr. pmid:21970991
Boleda MA et al. Behavior of pharmaceuticals and drugs of abuse in a drinking water treatment plant (DWTP) using combined conventional and ultrafiltration and reverse osmosis (UF/RO) treatments. 2011 Environ. Pollut. pmid:21459501
Zhang Z et al. Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21498135
Del Grosso M et al. Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. 2011 Antimicrob. Agents Chemother. pmid:21502613
Loreto ES et al. In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics. 2011 Antimicrob. Agents Chemother. pmid:21537028
Chen HX et al. [Compound erythromycin sustained release preparation and its in vitro release]. 2011 Yao Xue Xue Bao pmid:22260035
Park HH et al. The effect of macrolides on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. 2010 Sep-Oct Am J Rhinol Allergy pmid:21244734
Luiz DB et al. Identification of degradation products of erythromycin A arising from ozone and advanced oxidation process treatment. 2010 Sep-Oct Water Environ. Res. pmid:20942335
Al-Talib HI et al. Methicillin-resistant Staphylococcus aureus nosocomial infection trends in Hospital Universiti Sains Malaysia during 2002-2007. 2010 Sep-Oct Ann Saudi Med pmid:20697171
Murray MA et al. Ocular bacillary angiomatosis in an immunocompromised man. 2010 Sep-Oct Ophthal Plast Reconstr Surg pmid:20683276
Taneja N et al. Emergence of tetracycline resistance in Vibrio cholerae O1 biotype El Tor serotype Ogawa from north India. 2010 Oct-Dec Indian J Pathol Microbiol pmid:21045454
Dutil M Benzoyl peroxide: enhancing antibiotic efficacy in acne management. 2010 Nov-Dec Skin Therapy Lett. pmid:21076800
Levin TT et al. Case report: delirium due to a diltiazem-fentanyl CYP3A4 drug interaction. 2010 Nov-Dec Gen Hosp Psychiatry pmid:21112467
Bornstein E et al. Photodamage to multidrug-resistant gram-positive and gram-negative bacteria by 870 nm/930 nm light potentiates erythromycin, tetracycline and ciprofloxacin. 2010 May-Jun Photochem. Photobiol. pmid:20408973
Taylor SJ et al. Treating delayed gastric emptying in critical illness: metoclopramide, erythromycin, and bedside (cortrak) nasointestinal tube placement. 2010 May-Jun JPEN J Parenter Enteral Nutr pmid:20467010
Zhang LX et al. Febrile ulceronecrotic Mucha-Habermann's disease with pulmonary involvement. 2010 May-Jun Pediatr Dermatol pmid:20609148
Vorster M et al. Erythromycin as an alternative to reduce interfering extra-cardiac activity in myocardial perfusion imaging. 2010 May-Jun Cardiovasc J Afr pmid:20532452
Poulard F et al. Impact of not measuring residual gastric volume in mechanically ventilated patients receiving early enteral feeding: a prospective before-after study. 2010 Mar-Apr JPEN J Parenter Enteral Nutr pmid:19861528
Torrelo A et al. Extensive comedonal and cystic acne in Patau syndrome. 2010 Mar-Apr Pediatr Dermatol pmid:20537076
Armangil D et al. Maternal pertussis is hazardous for a newborn: a case report. 2010 Mar-Apr Turk. J. Pediatr. pmid:20560262
Tempera G et al. In vitro activity of cefditoren versus other antibiotics against S. pneumoniae clinical strains isolated in Italy. 2010 Jul-Sep Int J Immunopathol Pharmacol pmid:20943054
Pal N et al. Detection of inducible clindamycin resistance among Staphylococcal isolates from different clinical specimens in western India. 2010 Jul-Sep J Postgrad Med pmid:20739762
Darling EK and McDonald H A meta-analysis of the efficacy of ocular prophylactic agents used for the prevention of gonococcal and chlamydial ophthalmia neonatorum. 2010 Jul-Aug J Midwifery Womens Health pmid:20630358
Smith G Differential diagnosis of red eye. 2010 Jul-Aug Pediatr Nurs pmid:20860262
Dorobăţ OM et al. [Antibiotic resistance of Gram-positive cocci isolated in 2008]. 2010 Apr-Jun Bacteriol Virusol Parazitol Epidemiol pmid:21553473
Pană M et al. [Study of Streptococcus pneumoniae strains resistant to antibiotics analyzed at "Cantacuzino" NIRDMI during 2006-2008]. 2010 Apr-Jun Bacteriol Virusol Parazitol Epidemiol pmid:21553474
Nica M et al. [Bacterial strains isolated from systemic infections and reported for evaluation and antibiotic resistance surveillance by the "Dr. Victor BabeÅŸ" Clinical Hospital for Infectious and Tropical Diseases, Bucharest]. 2010 Apr-Jun Bacteriol Virusol Parazitol Epidemiol pmid:21553481
Namikawa H et al. Effect of erythromycin A and its new derivative EM201 on type I collagen production by cultured dermal fibroblasts. 2010 Arch. Dermatol. Res. pmid:19578864
Dhamdhere G et al. Interplay between drug efflux and antioxidants in Escherichia coli resistance to antibiotics. 2010 Antimicrob. Agents Chemother. pmid:20876376
He ZY et al. Effect of 6 months of erythromycin treatment on inflammatory cells in induced sputum and exacerbations in chronic obstructive pulmonary disease. 2010 Respiration pmid:20881376
Liu Y et al. 9-Dihydroerythromycin ethers as motilin agonists--developing structure-activity relationships for potency and safety. 2010 Bioorg. Med. Chem. pmid:20869254
Leszczyńska K et al. Modulation of exogenous antibiotic activity by host cathelicidin LL-37. 2010 APMIS pmid:20955455
Atkins JL et al. Enhancement of antimicrobial activity by synthetic ion channel synergy. 2010 Chem. Commun. (Camb.) pmid:20931142
van der Beek MT et al. Inaccuracy of routine susceptibility tests for detection of erythromycin resistance of Campylobacter jejuni and Campylobacter coli. 2010 Clin. Microbiol. Infect. pmid:19438640
Aguilera R C et al. [Antimicrobial susceptibility, capsular serotypes and clonal relationship of invasive streptococcus pneumoniae isolates in adult population of the Bio-Bio region, Chile. 2005-2006]. 2010 Rev Chilena Infectol pmid:21186502
Pazoki-Toroudi H et al. Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. 2010 J Dermatolog Treat pmid:20394495
Stringer E et al. Treatment of trichomoniasis in pregnancy in sub-Saharan Africa does not appear to be associated with low birth weight or preterm birth. 2010 S. Afr. Med. J. pmid:20429491
Chandra B et al. Catalytic asymmetric synthesis of complex polypropionates: Lewis base catalyzed aldol equivalents in the synthesis of erythronolide B. 2010 Angew. Chem. Int. Ed. Engl. pmid:20209542
Yao J et al. Novel enoyl-ACP reductase (FabI) potential inhibitors of Escherichia coli from Chinese medicine monomers. 2010 Bioorg. Med. Chem. Lett. pmid:19959361
Tokuda A et al. Effects of macrolides on antigen-induced increases in cough reflex sensitivity in guinea pigs. 2010 Pulm Pharmacol Ther pmid:19835975
Padilla E et al. Klebsiella pneumoniae AcrAB efflux pump contributes to antimicrobial resistance and virulence. 2010 Antimicrob. Agents Chemother. pmid:19858254
Glass SK et al. Canadian province-level risk factor analysis of macrolide consumption patterns (2000-2006). 2010 J. Antimicrob. Chemother. pmid:19864333
Goetting-Minesky MP and Fenno JC A simplified erythromycin resistance cassette for Treponema denticola mutagenesis. 2010 J. Microbiol. Methods pmid:20691222
Mazzoncini JP et al. Human metapneumovirus: an emerging respiratory pathogen. 2010 J Emerg Med pmid:18584996
Banche G et al. Synergistic effect of erythromycin on polymorphonuclear cell antibacterial activity against erythromycin-resistant phenotypes of Streptococcus pyogenes. 2010 Int. J. Antimicrob. Agents pmid:20692129
Shi HY et al. Effects of erythromycin on voriconazole pharmacokinetics and association with CYP2C19 polymorphism. 2010 Eur. J. Clin. Pharmacol. pmid:20669013
Bourne CR et al. Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1. 2010 Antimicrob. Agents Chemother. pmid:20606069
Bohnert JA et al. Optimized Nile Red efflux assay of AcrAB-TolC multidrug efflux system shows competition between substrates. 2010 Antimicrob. Agents Chemother. pmid:20606071
Horner P Chlamydia (uncomplicated, genital). 2010 BMJ Clin Evid pmid:21718568
Ren W et al. Efficacy of periprosthetic erythromycin delivery for wear debris-induced inflammation and osteolysis. 2010 Inflamm. Res. pmid:20607583
Ortiz-Pérez A et al. High frequency of macrolide resistance mechanisms in clinical isolates of Corynebacterium species. 2010 Microb. Drug Resist. pmid:20624090
Dundar D et al. Macrolide and tetracycline resistance and emm type distribution of Streptococcus pyogenes isolates recovered from Turkish patients. 2010 Microb. Drug Resist. pmid:20624096
Zhang H et al. Investigating the role of native propionyl-CoA and methylmalonyl-CoA metabolism on heterologous polyketide production in Escherichia coli. 2010 Biotechnol. Bioeng. pmid:19806677
Harris JB et al. Cholera's western front. 2010 Lancet pmid:21112083
Kwatra D et al. Interaction of gatifloxacin with efflux transporters: a possible mechanism for drug resistance. 2010 Int J Pharm pmid:20573570
Ying L and Tang D Recent advances in the medicinal chemistry of novel erythromycin-derivatized antibiotics. 2010 Curr Top Med Chem pmid:20536419
Fernandes NF et al. Pityriasis lichenoides et varioliformis acuta: a disease spectrum. 2010 Int. J. Dermatol. pmid:20465660
El-Mahdy TS et al. Detection of a new erm(X)-mediated antibiotic resistance in Egyptian cutaneous propionibacteria. 2010 Anaerobe pmid:20541615
Kana BD et al. Depletion of resuscitation-promoting factors has limited impact on the drug susceptibility of Mycobacterium tuberculosis. 2010 J. Antimicrob. Chemother. pmid:20542905
Kadlec K and Schwarz S Identification of the novel dfrK-carrying transposon Tn559 in a porcine methicillin-susceptible Staphylococcus aureus ST398 strain. 2010 Antimicrob. Agents Chemother. pmid:20498309
Levêque D et al. [Mechanisms of pharmacokinetic drug-drug interactions]. 2010 Rev Med Interne pmid:19740579
Woosley LN et al. CEM-101 activity against Gram-positive organisms. 2010 Antimicrob. Agents Chemother. pmid:20176910
Mulhbacher J et al. Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways. 2010 PLoS Pathog. pmid:20421948
Morrow BJ et al. In vitro antibacterial activities of JNJ-Q2, a new broad-spectrum fluoroquinolone. 2010 Antimicrob. Agents Chemother. pmid:20176911
Fraser RJ and Bryant L Current and future therapeutic prokinetic therapy to improve enteral feed intolerance in the ICU patient. 2010 Nutr Clin Pract pmid:20130155
Cocco G and Gasparyan AY Myocardial ischemia in Wegener's granulomatosis: coronary atherosclerosis versus vasculitis. 2010 Open Cardiovasc Med J pmid:20360980
Auerbach T et al. The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20080686
Krenauer A et al. EBV-associated post-transplantation B-cell lymphoproliferative disorder following allogenic stem cell transplantation for acute lymphoblastic leukaemia: tumor regression after reduction of immunosuppression--a case report. 2010 Diagn Pathol pmid:20356360
Cousens S et al. Antibiotics for pre-term pre-labour rupture of membranes: prevention of neonatal deaths due to complications of pre-term birth and infection. 2010 Int J Epidemiol pmid:20348116
Di Luca MC et al. Lysogenic transfer of mef(A) and tet(O) genes carried by Phim46.1 among group A streptococci. 2010 Antimicrob. Agents Chemother. pmid:20643900