erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Nie XP et al. Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole exposure to the antioxidant system in Pseudokirchneriella subcapitata. 2013 Environ. Pollut. pmid:22982550
Ishihara K et al. Distribution of antimicrobial-resistant lactic acid bacteria in natural cheese in Japan. 2013 Microbiol. Immunol. pmid:23930694
Pedersen JM et al. Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). 2013 Toxicol. Sci. pmid:24014644
Zhang L et al. Design, synthesis and biological evaluation of azithromycin glycosyl derivatives as potential antibacterial agents. 2013 Bioorg. Med. Chem. Lett. pmid:23937982
Herath SC and Poole P Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD). 2013 Cochrane Database Syst Rev pmid:24288145
Liang JH and Han X Structure-activity relationships and mechanism of action of macrolides derived from erythromycin as antibacterial agents. 2013 Curr Top Med Chem pmid:24200358
Matejcek A and Goldman RD Treatment and prevention of ophthalmia neonatorum. 2013 Can Fam Physician pmid:24235191
Kamal A et al. Anti-tubercular agents. Part 8: synthesis, antibacterial and antitubercular activity of 5-nitrofuran based 1,2,3-triazoles. 2013 Bioorg. Med. Chem. Lett. pmid:24206766
Rallis E et al. Topical 5% benzoyl peroxide and 3% erythromycin gel: experience with 191 patients with papulopustular acne. 2013 Acta Dermatovenerol Croat pmid:24183219
Sugino K et al. Granulomatous-lymphocytic interstitial lung disease in a patient with common variable immunodeficiency. 2013 Intern. Med. pmid:24292765
Wang X et al. Mesoporous titanium zirconium oxide nanospheres with potential for drug delivery applications. 2013 ACS Appl Mater Interfaces pmid:24150740
Wu C et al. Identification of elaiophylin derivatives from the marine-derived actinomycete Streptomyces sp. 7-145 using PCR-based screening. 2013 J. Nat. Prod. pmid:24164206
Arao M et al. Clostridium difficile colitis induced by long-term low-dosage erythromycin. 2013 Pediatr. Infect. Dis. J. pmid:24008746
Kirm B et al. SACE_5599, a putative regulatory protein, is involved in morphological differentiation and erythromycin production in Saccharopolyspora erythraea. 2013 Microb. Cell Fact. pmid:24341557
Olender A et al. The cause of Actinomyces canalictulis--a case study. 2013 Ann Agric Environ Med pmid:24364446
Yin YD et al. [Survey of macrolide resistance in Mycoplasma pneumoniae in adult patients with community-acquired pneumonia in Beijing, China]. 2013 Zhonghua Jie He He Hu Xi Za Zhi pmid:24503430
Ansari NN et al. Treatment of chronic rhinosinusitis using erythromycin phonophoresis. 2013 Physiother Theory Pract pmid:22891948
Chen DK et al. [Mechanism of hetero-erythromycin resistant Staphylococcus aureus and a comparison of detection methods]. 2013 Zhonghua Yi Xue Za Zhi pmid:24548451
Koulaouzidis A et al. Do prokinetics influence the completion rate in small-bowel capsule endoscopy? A systematic review and meta-analysis. 2013 Curr Med Res Opin pmid:23790243
Lin MH et al. Penetration of erythromycin through Staphylococcus epidermidis biofilm. 2013 Chin. Med. J. pmid:23876889
Winnicka K et al. The effect of PAMAM dendrimers on the antibacterial activity of antibiotics with different water solubility. 2013 Molecules pmid:23881050
Hennenberg M et al. The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction. 2013 J. Biomed. Sci. pmid:23815815
Mu Y et al. Synergistic effects of anti-CmeA and anti-CmeB peptide nucleic acids on sensitizing Campylobacter jejuni to antibiotics. 2013 Antimicrob. Agents Chemother. pmid:23817373
González-Abad MJ and Alonso-Sanz M [Incidence and susceptibility of Campylobacter jejuni in pediatric patients: involvement in bacteremia]. 2013 Rev Esp Quimioter pmid:23817644
Sanz-Rodríguez N et al. [Accuracy of Etest method to study Campylobacter spp. susceptibility to erythromycin, ciprofloxacin and tetracycline]. 2013 Rev Esp Quimioter pmid:23817649
James GD et al. Use of long-term antibiotic treatment in COPD patients in the UK: a retrospective cohort study. 2013 Prim Care Respir J pmid:23839240
Mu X et al. Effects of erythromycin and rifampicin on immunomodulatory gene expression and cellular function in human polymorphonuclear leukocytes. 2013 Chemotherapy pmid:24852442
Oplinger RW and Wagner EJ Control of Flavobacterium psychrophilum: tests of erythromycin, streptomycin, osmotic and thermal shocks, and rapid pH change. 2013 J. Aquat. Anim. Health pmid:23241009
Chae HS et al. Use of a novel Escherichia coli-leuconostoc shuttle vector for metabolic engineering of Leuconostoc citreum to overproduce D-lactate. 2013 Appl. Environ. Microbiol. pmid:23241984
Papapetropoulos N et al. Abscesses and wound infections due to Staphylococcus lugdunensis: report of 16 cases. 2013 Infection pmid:23242962
Berger A et al. Two cases of cutaneous diphtheria associated with occupational pig contact in Germany. 2013 Zoonoses Public Health pmid:23280311
Juntunen P et al. Absence of tetracycline resistance in Campylobacter coli isolates from Finnish finishing pigs treated with chlortetracycline. 2013 J. Appl. Microbiol. pmid:23282197
Mavri A and Smole Možina S Resistance to bile salts and sodium deoxycholate in macrolide- and fluoroquinolone-susceptible and resistant Campylobacter jejuni and Campylobacter coli strains. 2013 Microb. Drug Resist. pmid:23289436
Lin KJ et al. Safety of macrolides during pregnancy. 2013 Am. J. Obstet. Gynecol. pmid:23254249
Sánchez Valenzuela A et al. Phenotypic and molecular antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium isolated from different traditional fermented foods. 2013 Foodborne Pathog. Dis. pmid:23259502
Sanad YM et al. Molecular epidemiology and public health relevance of Campylobacter isolated from dairy cattle and European starlings in Ohio, USA. 2013 Foodborne Pathog. Dis. pmid:23259503
Drago L et al. Phenotypic and genotypic antibiotic resistance in some probiotics proposed for medical use. 2013 Int. J. Antimicrob. Agents pmid:23313535
Sanger GJ et al. Motilin: towards a new understanding of the gastrointestinal neuropharmacology and therapeutic use of motilin receptor agonists. 2013 Br. J. Pharmacol. pmid:23189978
Rams TE et al. Antibiotic susceptibility of periodontal Enterococcus faecalis. 2013 J. Periodontol. pmid:23106507
Osterman IA et al. A nascent proteome study combining click chemistry with 2DE. 2013 Proteomics pmid:23161590
Elborn JS and Tunney MM Macrolides and bronchiectasis: clinical benefit with a resistance price. 2013 JAMA pmid:23532247
Chan BC et al. Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase. 2013 Phytomedicine pmid:23541215
Tarran R et al. Nonantibiotic macrolides prevent human neutrophil elastase-induced mucus stasis and airway surface liquid volume depletion. 2013 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:23542952
Reveiz L and Cardona AF Antibiotics for acute laryngitis in adults. 2013 Cochrane Database Syst Rev pmid:23543536
Moriya S et al. Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells. 2013 Int. J. Oncol. pmid:23546223
Akiyoshi T et al. Mechanism-based inhibition profiles of erythromycin and clarithromycin with cytochrome P450 3A4 genetic variants. 2013 Drug Metab. Pharmacokinet. pmid:23514827
Müller W et al. German Francisella tularensis isolates from European brown hares (Lepus europaeus) reveal genetic and phenotypic diversity. 2013 BMC Microbiol. pmid:23517149
Lasnier O et al. Two cases of corneal abrasions in children exposed to liquid detergent capsules. 2013 Can. J. Ophthalmol. pmid:23561618
Methicillin resistant Staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern. 2013 Indian J. Med. Res. pmid:23563381
Rogers GB et al. Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. 2013 Thorax pmid:23564400