erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Lung Neoplasms D008175 171 associated lipids
Adenocarcinoma D000230 166 associated lipids
Edema D004487 152 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hemolysis D006461 131 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Inflammation D007249 119 associated lipids
Hypertension D006973 115 associated lipids
Weight Gain D015430 101 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Leukemia D007938 74 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Pain D010146 64 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Psoriasis D011565 47 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Leukemia P388 D007941 43 associated lipids
Arthritis D001168 41 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Hypotension D007022 41 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Nervous System Diseases D009422 37 associated lipids
Lung Diseases D008171 37 associated lipids
Heart Failure D006333 36 associated lipids
Epilepsy D004827 35 associated lipids
Acne Vulgaris D000152 35 associated lipids
Fever D005334 35 associated lipids
Glomerulonephritis D005921 35 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Uremia D014511 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Diarrhea D003967 32 associated lipids
Liver Diseases D008107 31 associated lipids
Cardiomegaly D006332 31 associated lipids
Drug Eruptions D003875 30 associated lipids
Dermatitis D003872 30 associated lipids
Obesity D009765 29 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Nasal Polyps D009298 26 associated lipids
Pseudomonas Infections D011552 25 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
He M et al. Dynamics of serotype 14 Streptococcus pneumoniae population causing acute respiratory infections among children in China (1997-2012). 2015 BMC Infect. Dis. pmid:26163293
Piccinelli G et al. Characterization and antibiotic susceptibility of Streptococcus agalactiae isolates causing urinary tract infections. 2015 Infect. Genet. Evol. pmid:26144658
Wang P et al. Serotype distribution, antimicrobial resistance, and molecular characterization of invasive group B Streptococcus isolates recovered from Chinese neonates. 2015 Int. J. Infect. Dis. pmid:26141418
Høye S An extraordinary tale of an ordinary case. 2015 Tidsskr. Nor. Laegeforen. pmid:26130550
Romaniszyn D et al. Epidemiology, antibiotic consumption and molecular characterisation of Staphylococcus aureus infections--data from the Polish Neonatology Surveillance Network, 2009-2012. 2015 BMC Infect. Dis. pmid:25888217
Park JY et al. Construction of a shuttle vector based on the small cryptic plasmid pJY33 from Weissella cibaria 33. 2015 Plasmid pmid:25882072
Jakubů V et al. Minimum inhibitory concentrations of erythromycin and other antibiotics for Czech strains of Bordetella pertussis. 2015 Epidemiol Mikrobiol Imunol pmid:25872990
Koutsogiannidis CP et al. Decreased DNA Disruption in the Porcine Neocortex with Erythromycin Preconditioning during Prolonged Hypothermic Circulatory Arrest: Evidence for Neuroprotection. 2015 J Card Surg pmid:25858150
Kovač J et al. Antibiotic resistance modulation and modes of action of (-)-α-pinene in Campylobacter jejuni. 2015 PLoS ONE pmid:25830640
Naquin A et al. Presence of antibiotic resistance genes in a sewage treatment plant in Thibodaux, Louisiana, USA. 2015 Bioresour. Technol. pmid:25662190
García-Mayor MA et al. Occurrence of erythromycin residues in sheep milk. Validation of an analytical method. 2015 Food Chem. Toxicol. pmid:25637760
van Eijk E et al. Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5. 2015 BMC Genomics pmid:25636331
Gao P et al. Impacts of coexisting antibiotics, antibacterial residues, and heavy metals on the occurrence of erythromycin resistance genes in urban wastewater. 2015 Appl. Microbiol. Biotechnol. pmid:25631280
Blix HS et al. Antibiotic prescriptions and cycles of Mycoplasma pneumoniae infections in Norway: can a nationwide prescription register be used for surveillance? 2015 Epidemiol. Infect. pmid:25388750
Lo HH et al. Antibiotic susceptibility pattern and erythromycin resistance mechanisms in beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates from central Taiwan. 2015 J Microbiol Immunol Infect pmid:24856419
Li X et al. Differential roles of the hemerythrin-like proteins of Mycobacterium smegmatis in hydrogen peroxide and erythromycin susceptibility. 2015 Sci Rep pmid:26607739
Cheng C et al. Ciprofloxacin plus erythromycin or ambroxol ameliorates endotracheal tube-associated Pseudomonas aeruginosa biofilms in a rat model. 2015 Pathol. Res. Pract. pmid:26601615
O'Connor SE Engineering of Secondary Metabolism. 2015 Annu. Rev. Genet. pmid:26393965
Borges V et al. Helicobacter pullorum isolated from fresh chicken meat: antibiotic resistance and genomic traits of an emerging foodborne pathogen. 2015 Appl. Environ. Microbiol. pmid:26386065
Dixit S and Park JH Enantioseparation of basic chiral drugs on a carbamoylated erythromycin-zirconia hybrid monolith using capillary electrochromatography. 2015 J Chromatogr A pmid:26372443
Michael-Kordatou I et al. Erythromycin oxidation and ERY-resistant Escherichia coli inactivation in urban wastewater by sulfate radical-based oxidation process under UV-C irradiation. 2015 Water Res. pmid:26360228
Ozbayram EG et al. Acute effects of various antibiotic combinations on acetoclastic methanogenic activity. 2015 Environ Sci Pollut Res Int pmid:25408075
Aydın S et al. The joint acute effect of tetracycline, erythromycin and sulfamethoxazole on acetoclastic methanogens. 2015 Water Sci. Technol. pmid:25909721
Mazumdar G and Shome K Stevens-Johnson syndrome following use of metronidazole in a dental patient. 2014 Jan-Feb Indian J Pharmacol pmid:24550598
Ishibashi K et al. Short-term intravenous antimicrobial prophylaxis for elective rectal cancer surgery: results of a prospective randomized non-inferiority trial. 2014 Surg. Today pmid:23989910
Wang S et al. Comparison of microbial communities in sequencing batch reactors (SBRs) exposed to trace erythromycin and erythromycin-Hâ‚‚O. 2014 Appl. Microbiol. Biotechnol. pmid:24072160
Liao D et al. Quantitative differences between primary and secondary peristaltic contractions of the esophagus. 2014 Dig. Dis. Sci. pmid:24682721
Caierão J et al. Serotypes and genotypes of invasive Streptococcus pneumoniae before and after PCV10 implementation in southern Brazil. 2014 PLoS ONE pmid:25356595
Arenz S et al. Drug sensing by the ribosome induces translational arrest via active site perturbation. 2014 Mol. Cell pmid:25306253
Belén Flórez A et al. Molecular identification and quantification of tetracycline and erythromycin resistance genes in Spanish and Italian retail cheeses. 2014 Biomed Res Int pmid:25302306
Wyatt TA et al. cAMP-dependent protein kinase activation decreases cytokine release in bronchial epithelial cells. 2014 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25150062
Abarzúa F et al. [Prevalence of anal-vaginal colonization of Streptococcus agalactiae in third trimester of pregnancy and susceptibility to macrolides and lincosamides, in pregnant women controlled at Clínica Alemana Temuco, Southern Chile]. 2014 Rev Chilena Infectol pmid:25146205
Carls A et al. Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. 2014 Br J Clin Pharmacol pmid:25139487
Compain F et al. Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids. 2014 Antimicrob. Agents Chemother. pmid:25136004
Wagner G et al. [Childhood granulomatous periorificial dermatitis]. 2014 Hautarzt pmid:25115983
Mott M et al. Susceptibility profiles and correlation with pneumococcal serotypes soon after implementation of the 10-valent pneumococcal conjugate vaccine in Brazil. 2014 Int. J. Infect. Dis. pmid:24389158
Johansson M et al. Sequence-dependent elongation dynamics on macrolide-bound ribosomes. 2014 Cell Rep pmid:24836000
Borbón-Esquer EM et al. SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. 2014 Scand. J. Infect. Dis. pmid:24832853
Wang Z et al. High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. 2014 Clin. Microbiol. Infect. pmid:24816168
Allen LN Mild meningococcaemia, pyrexia protocols and a problematic public health response. 2014 BMJ Case Rep pmid:24811106
Mulatu G et al. Prevalence of Shigella, Salmonella and Campylobacter species and their susceptibility patters among under five children with diarrhea in Hawassa town, south Ethiopia. 2014 Ethiop J Health Sci pmid:24795510
Wu P et al. SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea. 2014 J. Ind. Microbiol. Biotechnol. pmid:24793123
Yosida M et al. Involvement of cAMP/EPAC/TRPM2 activation in glucose- and incretin-induced insulin secretion. 2014 Diabetes pmid:24824430
Siira L et al. Antimicrobial resistance in relation to sero- and genotypes among invasive Streptococcus pneumoniae in Finland, 2007-2011. 2014 Microb. Drug Resist. pmid:24266666
Benito D et al. Genetic lineages, antimicrobial resistance, and virulence in Staphylococcus aureus of meat samples in Spain: analysis of immune evasion cluster (IEC) genes. 2014 Foodborne Pathog. Dis. pmid:24479575
Boomkamp SD et al. Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. 2014 Br. J. Pharmacol. pmid:24467222
Jun BY et al. Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. 2014 Surg Endosc pmid:24380989
Ren WP et al. Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. 2014 J. Biomed. Mater. Res. Part B Appl. Biomater. pmid:24347324
Brenciani A et al. Genetic determinants and elements associated with antibiotic resistance in viridans group streptococci. 2014 J. Antimicrob. Chemother. pmid:24343896
Lu WC et al. Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. 2014 Neurol. Sci. pmid:24277204