erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Occupational Injuries D060051 1 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Lung Injury D055371 33 associated lipids
Atrioventricular Block D054537 1 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Seroma D049291 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Ileus D045823 3 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Pelvic Infection D034161 1 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Epidural Abscess D020802 1 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Sepsis D018805 11 associated lipids
Abdominal Abscess D018784 2 associated lipids
Arthralgia D018771 8 associated lipids
Gastroparesis D018589 2 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Acneiform Eruptions D017486 3 associated lipids
Skin Diseases, Vascular D017445 1 associated lipids
Skin Diseases, Papulosquamous D017444 2 associated lipids
Gastric Outlet Obstruction D017219 1 associated lipids
Skin Diseases, Viral D017193 2 associated lipids
Skin Diseases, Bacterial D017192 8 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Chalazion D017043 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Ragosta M et al. Potentially fatal interaction between erythromycin and disopyramide. 1989 Am. J. Med. pmid:2467560
Gumaste VV Erythromycin-induced pancreatitis. 1989 Am. J. Med. pmid:2729328
Curtis LH et al. Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients. 2003 Am. J. Med. pmid:12586234
Nattel S et al. Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism. 1990 Am. J. Med. pmid:2382671
Klein JO Emerging perspectives in management and prevention of infections of the respiratory tract in infants and children. 1985 Am. J. Med. pmid:4014286
Rudin JE et al. Failure of erythromycin in treatment of Legionella micdadei pneumonia. 1984 Am. J. Med. pmid:6607673
Diehl AM et al. Cholestatic hepatitis from erythromycin ethylsuccinate. Report of two cases. 1984 Am. J. Med. pmid:6609640
Parker RH et al. Erythromycin-resistant pneumococcal osteomyelitis. 1970 Am. J. Med. pmid:5415405
Sacristán JA and Soto J Erythromycin ototoxicity: methodology and conclusions. 1993 Am. J. Med. pmid:8430720
Tablan OC and Reyes MP Chronic interstitial pulmonary fibrosis following Mycoplasma pneumoniae pneumonia. 1985 Am. J. Med. pmid:4025379
DAVIS DS and ROMANSKY MJ Successful treatment of gonococcic endocarditis with erythromycin; review of the literature. 1956 Am. J. Med. pmid:13354638
Augenbraun MH et al. Chlamydia pneumoniae pneumonia with pleural effusion: diagnosis by culture. 1991 Am. J. Med. pmid:1951390
Swanson DJ et al. Erythromycin ototoxicity: prospective assessment with serum concentrations and audiograms in a study of patients with pneumonia. 1992 Am. J. Med. pmid:1731511
Friedland L et al. Ocular and pericardial involvement in Legionnaires' disease. 1984 Am. J. Med. pmid:6507461
Bolton WK et al. Ventriculojugular shunt nephritis with Corynebacterium bovis. Successful therapy with antibiotics. 1975 Am. J. Med. pmid:1163549
Stocks JM et al. Ofloxacin in community-acquired lower respiratory infections. A comparison with amoxicillin or erythromycin. 1989 Am. J. Med. pmid:2690620
Watanakunakorn C Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. 1976 Am. J. Med. pmid:1045861
Bowler WA et al. Gastrointestinal side effects of intravenous erythromycin: incidence and reduction with prolonged infusion time and glycopyrrolate pretreatment. 1992 Am. J. Med. pmid:1546723
Unertl KE et al. Ciprofloxacin in the treatment of legionellosis in critically ill patients including those cases unresponsive to erythromycin. 1989 Am. J. Med. pmid:2589356
SOLOMON S and JOHNSTON B The clinical use of erythromycin. 1955 Am. J. Med. Sci. pmid:13268445
Kislak JW et al. Susceptibility of pneumococci to nine antibiotics. 1965 Am. J. Med. Sci. pmid:4378532
Kayser FH and Mak TM Methicillin-resistant staphylococci. 1972 Am. J. Med. Sci. pmid:4486503
AUSTRIAN R and ROSENBLUM R The relative efficacy of erythromycin (ilotycin) and of penicillin in the treatment of pneumococcal lobar pneumonia. 1953 Am. J. Med. Sci. pmid:13104398
Simon HJ Antimicrobial susceptibility of group D hemolytic streptococci (enterococci). 1967 Am. J. Med. Sci. pmid:5180810
BLOUGH HA et al. Serum levels and clinical results with erythromycin propionate. 1960 Am. J. Med. Sci. pmid:13801645
CICCANTELLI MJ and GARRY MW Erythromycin: an evaluation for clinical toxicity. 1956 Am. J. Med. Sci. pmid:13362260
ROBINSON MM Hepatic dysfunction associated with triacetyloleandomycin and propionyl erythromycin ester lauryl sulfate. 1962 Am. J. Med. Sci. pmid:14492926
Devasia RA et al. Compliance with azithromycin versus erythromycin in the setting of a pertussis outbreak. 2009 Am. J. Med. Sci. pmid:19301451
Williams ME et al. Legionnaires' disease with acute renal failure. 1980 May-Jun Am. J. Med. Sci. pmid:7424965
Toala P et al. Susceptibility of group D streptococcus (enterococcus) to 21 antibiotics in vitro, with special reference to species differences. 1969 Am. J. Med. Sci. pmid:4984452
HIRSCH HA and FINLAND M Effect of food on the absorption of erythromycin propionate, erythromycin stearate and triacetyloleandomycin. 1959 Am. J. Med. Sci. pmid:13661157
Holoshitz J et al. Listeria monocytogenes pericarditis in a chronically hemodialyzed patient. 1984 Jul-Aug Am. J. Med. Sci. pmid:6465192
Feigin RD et al. Treatment of penicillin-resistant staphylococcal infections with clindamycin. 1971 Am. J. Med. Sci. pmid:5578775
GRIFFITH RS and BLACK HR COMPARISON OF THE BLOOD LEVELS OBTAINED AFTER SINGLE AND MULTIPLE DOSES OF ERYTHROMYCIN ESTOLATE AND ERYTHROMYCIN STEARATE. 1964 Am. J. Med. Sci. pmid:14106882
Rodríguez-Gutiérrez R et al. Herpes zoster ophthalmicus masked by hymenoptera stings. 2014 Am. J. Med. Sci. pmid:23085675
HIRSCH HA et al. Effect of food on absorption of a new form of erythromycin propionate. 1960 Am. J. Med. Sci. pmid:14401969
McGehee RF et al. Comparative studies of antibacterial activity in vitro and absorption and excretion of lincomycin and clinimycin. 1968 Am. J. Med. Sci. pmid:4386950
Oppenheimer S and Turek M Laboratory and clinical evaluation of 7-chloro-7-deoxylincomycin. 1968 Am. J. Med. Sci. pmid:4386951
CLAPPER WE et al. THE SUSCEPTIBILITY OF CERTAIN BACTERIA TO LINCOMYCIN AS RELATED TO ATTAINABLE SERUM LEVELS IN HUMAN ADULTS. 1964 Am. J. Med. Sci. pmid:14130319
FISCHER HW and HOAK JC MIMICRY OF ACUTE CHOLECYSTITIS BY ERYTHROMYCIN ESTOLATE REACTIONS. REPORT OF 2 CASES. 1964 Am. J. Med. Sci. pmid:14130320
McCabe WR and Lorian V Comparison of the antibacterial activity of rifampicin and other antibiotics. 1968 Am. J. Med. Sci. pmid:4387027
Martinez JA et al. Diffuse panbronchiolitis in Latin America. 2000 Am. J. Med. Sci. pmid:10746829
Baird IM et al. Case report. Clinical manifestations and treatment of Legionnaires' disease. 1979 Mar-Apr Am. J. Med. Sci. pmid:463949
Gray BM Case report: Rhodococcus equi pneumonia in a patient infected by the human immunodeficiency virus. 1992 Am. J. Med. Sci. pmid:1595781
Rao KV and Ralston RA Meningitis due to Campylobacter fetus intestinalis in a kidney transplant recipient. A case report. 1987 Am. J. Nephrol. pmid:3324765
Beckner RR et al. Ototoxicity of erythromycin gluceptate. 1981 Am. J. Obstet. Gynecol. pmid:7211980
Friberg J Genital mycoplasma infections. 1978 Am. J. Obstet. Gynecol. pmid:362924
Alger LS and Lovchik JC Comparative efficacy of clindamycin versus erythromycin in eradication of antenatal Chlamydia trachomatis. 1991 Am. J. Obstet. Gynecol. pmid:1872343
Owen J et al. Randomized trial of prophylactic antibiotic therapy after preterm amnion rupture. 1993 Am. J. Obstet. Gynecol. pmid:8238160
Yost NP et al. An appraisal of treatment guidelines for antepartum community-acquired pneumonia. 2000 Am. J. Obstet. Gynecol. pmid:10920320