erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Hargreaves CA et al. | Effects of co-trimoxazole, erythromycin, amoxycillin, tetracycline and chloroquine on sperm function in vitro. | 1998 | Hum. Reprod. | pmid:9740442 |
Barg N | Comparison of four antibiotics in a murine model of necrotizing cutaneous infections caused by toxigenic Streptococcus pyogenes and Staphylococcus aureus. | 1998 | J. Antimicrob. Chemother. | pmid:9738847 |
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Colsky AS et al. | Analysis of antibiotic susceptibilities of skin wound flora in hospitalized dermatology patients. The crisis of antibiotic resistance has come to the surface. | 1998 | Arch Dermatol | pmid:9722732 |
Paul VK et al. | Erythromycin treatment of pregnant women to reduce the incidence of low birth weight and preterm deliveries. | 1998 | Int J Gynaecol Obstet | pmid:9722132 |
Kessie G et al. | Plasmid profile and antibiotic resistance in coagulase-negative staphylococci isolated from polluted water. | 1998 | J. Appl. Microbiol. | pmid:9721646 |
Reeves AR et al. | Physical-genetic map of the erythromycin-producing organism Saccharopolyspora erythraea. | 1998 | Microbiology (Reading, Engl.) | pmid:9720036 |
Faghih R et al. | Synthesis of 9-deoxo-4''-deoxy-6,9-epoxyerythromycin derivatives: novel and acid-stable motilides. | 1998 | J. Med. Chem. | pmid:9719592 |
Korting HC et al. | Current antimicrobial susceptibility of cutaneous bacteria to first line antibiotics. | 1998 | Int. J. Antimicrob. Agents | pmid:9716294 |
Kent S et al. | T wave alternans associated with HIV cardiomyopathy, erythromycin therapy, and electrolyte disturbances. | 1998 | South. Med. J. | pmid:9715223 |
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Cornaglia G et al. | Resistance of Streptococcus pyogenes to erythromycin and related antibiotics in Italy. The Italian Surveillance Group for Antimicrobial Resistance. | 1998 | Clin. Infect. Dis. | pmid:9710676 |
Doherty TJ et al. | Acetaminophen as a marker of gastric emptying in ponies. | 1998 | Equine Vet. J. | pmid:9705120 |
Takamori M et al. | [A case of legionnaire's disease due to Legionella pneumophila serogroup 6]. | 1998 | Nippon Naika Gakkai Zasshi | pmid:9702025 |
Takizawa H et al. | Erythromycin and clarithromycin attenuate cytokine-induced endothelin-1 expression in human bronchial epithelial cells. | 1998 | Eur. Respir. J. | pmid:9701415 |
Pearlman MD et al. | Frequent resistance of clinical group B streptococci isolates to clindamycin and erythromycin. | 1998 | Obstet Gynecol | pmid:9699763 |
Wagner D | CYP3A4 and the erythromycin breath test. | 1998 | Clin. Pharmacol. Ther. | pmid:9695728 |
Woo EK et al. | Multiple antibiotic resistance in Streptococcus pneumoniae. | 1998 | Med. J. Aust. | pmid:9695709 |
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Minas W et al. | Improved erythromycin production in a genetically engineered industrial strain of Saccharopolyspora erythraea. | 1998 Jul-Aug | Biotechnol. Prog. | pmid:9694676 |
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Weissman KJ et al. | Origin of starter units for erythromycin biosynthesis. | 1998 | Biochemistry | pmid:9692995 |
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