erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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De Azavedo JC et al. | Prevalence and mechanisms of macrolide resistance in clinical isolates of group A streptococci from Ontario, Canada. | 1999 | Antimicrob. Agents Chemother. | pmid:10471555 |
Huovinen P | Causes, diagnosis and treatment of pharyngitis. | 1999 Jun-Jul | Compr Ther | pmid:10470516 |
Di Lorenzo C et al. | Effect of sequential erythromycin and octreotide on antroduodenal manometry. | 1999 | J. Pediatr. Gastroenterol. Nutr. | pmid:10467994 |
Manners BT et al. | An investigation of antibiotic resistance of Staphylococcus aureus in general practice. | 1976 | Practitioner | pmid:1046672 |
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Odland BA et al. | Antimicrobial activity of gatifloxacin (AM-1155, CG5501), and four other fluoroquinolones tested against 2,284 recent clinical strains of Streptococcus pneumoniae from Europe, Latin America, Canada, and the United States. The SENTRY Antimicrobial Surveillance Group (Americas and Europe). | 1999 | Diagn. Microbiol. Infect. Dis. | pmid:10459483 |
Boyanova L et al. | Characteristics and trends in macrolide resistance among Helicobacter pylori strains isolated in Bulgaria over four years. | 1999 | Diagn. Microbiol. Infect. Dis. | pmid:10459482 |
Watanakunakorn C | Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. | 1976 | Am. J. Med. | pmid:1045861 |
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Morales WJ et al. | Change in antibiotic resistance of group B streptococcus: impact on intrapartum management. | 1999 | Am. J. Obstet. Gynecol. | pmid:10454674 |
Tamaoki J et al. | Macrolide antibiotics protect against immune complex-induced lung injury in rats: role of nitric oxide from alveolar macrophages. | 1999 | J. Immunol. | pmid:10453038 |
Wang H et al. | Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro. | 1999 | Zhongguo Yao Li Xue Bao | pmid:10452125 |
Cohen J et al. | Mediterranean spotted fever in pregnancy. | 1999 | Scand. J. Infect. Dis. | pmid:10447334 |
Vorland LH et al. | Interference of the antimicrobial peptide lactoferricin B with the action of various antibiotics against Escherichia coli and Staphylococcus aureus. | 1999 | Scand. J. Infect. Dis. | pmid:10447328 |
Jones KL et al. | The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. | 1999 | Am. J. Gastroenterol. | pmid:10445530 |
Moss AJ et al. | A review of the cardiac systemic side-effects of antihistamines: ebastine. | 1999 | Clin. Exp. Allergy | pmid:10444238 |
Schiano P et al. | [Gastroparesis of central origin: usefulness of erythromycin]. | 1999 | Can J Anaesth | pmid:10442972 |
Limia A et al. | Five-year analysis of antimicrobial susceptibility of the Streptococcus milleri group. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10442424 |
Albini E et al. | Activity of aerosol thiamphenicol glycinate acetylcysteinate in a mouse model of S. pyogenes pneumonia. | 1999 | Arzneimittelforschung | pmid:10442213 |
Blackwell BA et al. | Oxidative deamination of hydrolyzed fumonisin B(1) (AP(1)) by cultures of Exophiala spinifera. | 1999 | Nat. Toxins | pmid:10441035 |
Kearney GC et al. | Structural elucidation studies of erythromycins by electrospray tandem mass spectrometry II. | 1999 | Rapid Commun. Mass Spectrom. | pmid:10440983 |
Sakai C et al. | Nocardia asteroides pneumonia, subcutaneous abscess and meningitis in a patient with advanced malignant lymphoma: successful treatment based on in vitro antimicrobial susceptibility. | 1999 | Intern. Med. | pmid:10440509 |
Drug interactions. | 1999 | Med Lett Drugs Ther | pmid:10436770 | |
Kumar A and Will EJ | Necrotizing fasciitis and Legionnaires' disease after combined renal and pancreatic transplantation: a penalty of overseas travel. | 1999 | Nephrol. Dial. Transplant. | pmid:10435897 |
Barone A et al. | Microbiotica associated with refractory periodontis. Prevalence and antibiotic susceptibility. | 1999 | Minerva Stomatol | pmid:10434536 |
Krecic-Shepard ME et al. | In vivo comparison of putative probes of CYP3A4/5 activity: erythromycin, dextromethorphan, and verapamil. | 1999 | Clin. Pharmacol. Ther. | pmid:10430108 |
Credito KL et al. | Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. | 1999 | Antimicrob. Agents Chemother. | pmid:10428930 |
Giovanetti E et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains in Italy and heterogeneity of inducibly resistant strains. | 1999 | Antimicrob. Agents Chemother. | pmid:10428916 |
Johnson MM et al. | Effect of carbon dioxide on testing of susceptibilities of respiratory tract pathogens to macrolide and azalide antimicrobial agents. | 1999 | Antimicrob. Agents Chemother. | pmid:10428903 |
Callréus T et al. | Changes in gastrointestinal motility influence the absorption of desmopressin. | 1999 | Eur. J. Clin. Pharmacol. | pmid:10424324 |
Bachmann K et al. | A study of the interaction between dirithromycin and astemizole in healthy adults. | 1997 Feb-Mar | Am J Ther | pmid:10423595 |
Okada J et al. | [Changes of antimicrobial susceptibility of anaerobic bacteria from clinical specimens (author's transl)]. | 1975 | Jpn J Antibiot | pmid:1042183 |
Cvetkovic M et al. | OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. | 1999 | Drug Metab. Dispos. | pmid:10421612 |
Latorre G et al. | [Chlamydia pneumoniae pneumonia]. | 1998 Jan-Mar | Rev Med Univ Navarra | pmid:10420952 |
de Sousa G et al. | A multi-laboratory evaluation of cryopreserved monkey hepatocyte functions for use in pharmaco-toxicology. | 1999 | Chem. Biol. Interact. | pmid:10418972 |
Kearney JA et al. | In vitro activities of the oxazolidinone compounds linezolid (PNU-100766) and eperzolid (PNU-100592) against middle ear isolates of Streptococcus pneumoniae. | 1999 | Int. J. Antimicrob. Agents | pmid:10418759 |
Albini E et al. | In vitro antibacterial activity of thiamphenicol glycinate acetylcysteinate against respiratory pathogens. | 1999 | Arzneimittelforschung | pmid:10417871 |
Lee DO and Lee CD | Serotonin syndrome in a child associated with erythromycin and sertraline. | 1999 | Pharmacotherapy | pmid:10417041 |
Matsumoto H et al. | Sensitivity of fresh isolates of Haemophilus to current antibiotics. | 1975 | Jpn J Antibiot | pmid:1041598 |
Finegold SM | Antimicrobial therapy of anaerobic infections. | 1975 | Postgrad Med | pmid:1041514 |
Driessen JH | A computer study of bacterial resistance patterns to antibiotics. | 1975 | Chemotherapy | pmid:1041490 |
Lin CF and Chung TC | Cloning of erythromycin-resistance determinants and replication origins from indigenous plasmids of Lactobacillus reuteri for potential use in construction of cloning vectors. | 1999 | Plasmid | pmid:10413663 |
Wagenvoort JH et al. | How useful is the Chlamydia micro-immunofluorescence (MIF) test for the gynaecologist? | 1999 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:10413220 |
Drici MD et al. | Comparison of tegaserod (HTF 919) and its main human metabolite with cisapride and erythromycin on cardiac repolarization in the isolated rabbit heart. | 1999 | J. Cardiovasc. Pharmacol. | pmid:10413072 |
Messini M et al. | Bacteremia after dental treatment in mentally handicapped people. | 1999 | J. Clin. Periodontol. | pmid:10412852 |
Oguri T et al. | [Multiple drug resistance of Enterobacter-Serratia group isolated from clinical materials (author's transl)]. | 1975 | Jpn J Antibiot | pmid:1041281 |