erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Wong PW et al. | Multiple organ toxicity from addition of erythromycin to long-term lovastatin therapy. | 1998 | South. Med. J. | pmid:9496876 |
Kondoh K and Hashiba M | [Inhibitory effect of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. | 1998 | Nippon Jibiinkoka Gakkai Kaiho | pmid:9493436 |
Pereda A et al. | The loading domain of the erythromycin polyketide synthase is not essential for erythromycin biosynthesis in Saccharopolyspora erythraea. | 1998 | Microbiology (Reading, Engl.) | pmid:9493390 |
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Nalepa P and Micherdzińska K | [Severe pneumonia caused by Chlamydia pneumoniae in a patient treated with steroids for bronchial asthma]. | 1997 | Pol. Merkur. Lekarski | pmid:9461730 |
Rampling A et al. | Community-acquired Legionnaires' disease following minimal exposure to a contaminated source. | 1997 | J. Infect. | pmid:9459407 |
Pfaller MA et al. | In vitro activity of cefepime and ceftazidime against 197 nosocomial blood stream isolates of streptococci: a multicenter sample. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9458985 |
Pfaller MA et al. | Nosocomial streptococcal blood stream infections in the SCOPE Program: species occurrence and antimicrobial resistance. The SCOPE Hospital Study Group. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9458983 |
Borek AP et al. | Evolving clinical problems with Streptococcus pneumoniae: increasing resistance to antimicrobial agents, and failure of traditional optochin identification in Chicago, Illinois, between 1993 and 1996. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9458976 |
Mathis C and Malbert CH | Erythromycin gastrokinetic activity is partially vagally mediated. | 1998 | Am. J. Physiol. | pmid:9458776 |
Yeates RA et al. | Pharmacokinetic and pharmacodynamic interaction study between midazolam and the macrolide antibiotics, erythromycin, clarithromycin, and the azalide azithromycin. | 1997 | Int J Clin Pharmacol Ther | pmid:9455717 |
Shirai R et al. | [Analysis of cases allowed to cease erythromycin therapy for diffuse panbronchiolitis--comparative study between patients with cessation of the therapy and patients continuing the therapy]. | 1997 | Kansenshogaku Zasshi | pmid:9455056 |
Granados MA and French L | Antibiotic treatment in preterm PROM. | 1998 | J Fam Pract | pmid:9451358 |
Cocuzza CE et al. | High incidence of erythromycin-resistant Streptococcus pyogenes in Monza (North Italy) in untreated children with symptoms of acute pharyngo-tonsillitis: an epidemiological and molecular study. | 1997 | Microb. Drug Resist. | pmid:9442490 |
Chen B et al. | Ameliorating effect of erythromycin on bleomycin-induced pulmonary fibrosis: role of alveolar macrophage activation and cytokine release. | 1997 | Respirology | pmid:9441129 |
Fenton LJ and Light IJ | Congenital syphilis after maternal treatment with erythromycin. | 1976 | Obstet Gynecol | pmid:943741 |
Karbowski M et al. | Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes. | 1997 | Biochim. Biophys. Acta | pmid:9434138 |
Folwaczny C et al. | [Effects of various prokinetic drugs on gastrointestinal transit times in patients with progressive systemic scleroderma]. | 1997 | Z Gastroenterol | pmid:9432812 |
Freidank H | [Diagnosis and therapy of Chlamydia pneumoniae and trachomatis]. | 1997 | Internist (Berl) | pmid:9432510 |
Park HJ et al. | Effect of erythromycin on gastric emptying in healthy individuals assessed by radio-opaque markers and plasma acetaminophen levels. | 1997 | J. Gastroenterol. | pmid:9430010 |
Ross EA and Koo LC | Improved nutrition after the detection and treatment of occult gastroparesis in nondiabetic dialysis patients. | 1998 | Am. J. Kidney Dis. | pmid:9428453 |
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Martins JC et al. | Optimal detection of weak nJ(1H- 119Sn) couplings by gradient-enhanced 1D and 2D heteronuclear multiple-quantum correlation spectroscopy. Application to a novel tin derivative of erythromycin A. | 1997 | J. Magn. Reson. | pmid:9424309 |
Midolo PD et al. | Antimicrobial resistance testing of Helicobacter pylori: a comparison of Etest and disk diffusion methods. | 1997 | Pathology | pmid:9423225 |
Marsden AF et al. | Engineering broader specificity into an antibiotic-producing polyketide synthase. | 1998 | Science | pmid:9422686 |
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Guin JD et al. | Antibiotic sensitivity of comedonal Propionibacterium acnes. | 1979 | Acta Derm. Venereol. | pmid:94223 |
Fischman AJ et al. | The role of positron emission tomography in pharmacokinetic analysis. | 1997 | Drug Metab. Rev. | pmid:9421680 |