erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
pmid:5110814
pmid:16888699
pmid:17760348
pmid:
Sebrechts T et al. Serial Gastric Ultrasound to Evaluate Gastric Emptying After Prokinetic Therapy With Domperidone and Erythromycin in a Surgical Patient With a Full Stomach: A Case Report. 2018 A A Pract pmid:29634526
Mirza S et al. Influence of solvents on the variety of crystalline forms of erythromycin. 2003 AAPS PharmSci pmid:12866939
Mirza S et al. Crystal morphology engineering of pharmaceutical solids: tabletting performance enhancement. 2009 AAPS PharmSciTech pmid:19184449
Pignatello R et al. Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. 2011 AAPS PharmSciTech pmid:21479751
Petrakis IE et al. Hyperglycemia attenuates erythromycin-induced acceleration of solid-phase gastric emptying in healthy subjects. 2002 May-Jun Abdom Imaging pmid:12173362
Gore RM et al. Drug-induced disorders of the stomach and duodenum. 1999 Jan-Feb Abdom Imaging pmid:9933666
Wang X et al. Mesoporous titanium zirconium oxide nanospheres with potential for drug delivery applications. 2013 ACS Appl Mater Interfaces pmid:24150740
Leirós M et al. Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons. 2014 ACS Chem Neurosci pmid:24219236
McCusker KP and Fujimori DG The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance. 2012 ACS Chem. Biol. pmid:22208312
Koryakina I et al. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. 2017 ACS Chem. Biol. pmid:28103677
Sundermann U et al. Enzyme-directed mutasynthesis: a combined experimental and theoretical approach to substrate recognition of a polyketide synthase. 2013 ACS Chem. Biol. pmid:23181268
Buchholz TJ et al. Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains. 2009 ACS Chem. Biol. pmid:19146481
Kasey CM et al. Development of Transcription Factor-Based Designer Macrolide Biosensors for Metabolic Engineering and Synthetic Biology. 2018 ACS Synth Biol pmid:28950701
Tixador R et al. Preliminary results of Cytos 2 experiment. 1985 Acta Astronaut pmid:11542841
Raczyńska-Bojanowska K et al. Carboxylation of propionyl-CoA in erythromycin biosynthesis. 1970 Acta Biochim. Pol. pmid:5495362
Olajuyigbe OO et al. In vitro pharmacological interaction of caffeine and first-line antibiotics is antagonistic against clinically important bacterial pathogens. 2017 Acta Biochim. Pol. pmid:28612062
Klita S and Szafranśki P Comparison of the mechanism of action of cyclic 11,12-erythromycin A carbonate and erythromycin A. 1980 Acta Biochim. Pol. pmid:7023159
Ruczaj Z et al. On the release of enzymes upon lysozyme treatment of Streptomyces. 1969 Acta Biochim. Pol. pmid:4312597
Gottfredsson M and Steingrímsdóttir H Disseminated invasive aspergillosis in a patient with acute leukaemia. 2006 Acta Biomed pmid:16918060
Kocik L and Crnjakovic D [Injuries of the peripheral blood vessels]. 1976 Acta Chir Iugosl pmid:779378
WICKMAN K Nosocomial infection with erythromycin-resistant straphylococci in a burns and plastic surgery unit. 1958 Acta Chir Scand pmid:13532327
Biver A et al. [Coagulase positive staphylococci isolated from victims of severe burns]. 1971 Acta Chir. Belg. pmid:4948663
Lornoy W and Steyaert J Ototoxicity of erythromycin lactobionate. 1979 Acta Clin Belg pmid:314715
Yourassowsky E [Kinetics of the action of antibiotics in plasma medium]. 1967 Acta Clin Belg pmid:5594390
Vanhoof R et al. In vitro susceptibilities of 176 clinical isolates of Streptococcus pneumoniae to 11 beta-lactams, erythromycin, and tetracycline. 1996 Acta Clin Belg pmid:8997755
Harvengt C Clarithromycin-idarubicin. 1991 Acta Clin Belg pmid:1665945
YOURASSOWSKY E and BEUMER J [EPIDEMIOLOGICAL STUDY OF STAPHYLOCOCCUS AUREUS INFECTIONS AT THE BRUGMANN HOSPITAL]. 1963 Acta Clin Belg pmid:14045898
Devos H et al. Resistance of Campylobacter spp. to ciprofloxacin and erythromycin in a Belgian peripheral hospital. 2007 Nov-Dec Acta Clin Belg pmid:18351190
Monsieur I et al. Severe community-acquired pneumonia caused by atypical organisms. 1997 Acta Clin Belg pmid:9204587
Vanhoof R et al. In vitro evaluation of the antibiotic susceptibility of Streptococcus pneumoniae: pneumococci relatively resistant to penicillin in Brussels. 1980 Acta Clin Belg pmid:6916583
LAMBERT J et al. [Osler's endocarditis lenta with Streptococci resistant to other antibiotics cured by erythromycin]. 1955 Jan-Feb Acta Clin Belg pmid:14375643
Yourassowsky E [Sensitivity of gram negative bacilli to lincomycin and erythromycin in alkaline media]. 1971 Acta Clin Belg Suppl pmid:4948540
Lynch VM et al. Structure of a protected C3-C10 subunit of erythromycin and its C8 epimer. 1992 Acta Crystallogr C pmid:1388943
Lynch VM et al. A novel dioxabicyclo[3.3.1]nonane, a key intermediate in the synthesis of erythronolide B seco-acid. 1994 Acta Crystallogr C pmid:7946151
Lynch VM et al. Structure of a protected C(1)-C(10) subunit of C(2)-epi-erythronolides A and B. 1989 Acta Crystallogr C pmid:2610960
Lynch VM et al. Structure of a protected C(1)-C(10) subunit of erythronolides A and B. 1989 Acta Crystallogr C pmid:2610985
Langer V et al. Stereoisomers of 1,2-diaryl-1,3-propanediols: erythro forms. 2007 Acta Crystallogr C pmid:17339721
Davydova N et al. Crystals of a mutant form of ribosomal protein L22 rendering bacterial ribosomes resistant to erythromycin. 2001 Acta Crystallogr. D Biol. Crystallogr. pmid:11468402
Sanchez MA and Rorat E Fine needle aspiration diagnosis of intramuscular bacillary angiomatosis. A case report. 1996 Jul-Aug Acta Cytol. pmid:8693899
Bertini B et al. Cytopathology of nipple discharge due to Pityrosporum orbiculare and cocci in an elderly woman. 1975 Jan-Feb Acta Cytol. pmid:46660
Leyden JJ et al. Topical antibiotics and topical antimicrobial agents in acne therapy. 1980 Acta Derm Venereol Suppl (Stockh) pmid:6451130
Holm SE and Burman LG General considerations by a clinical bacteriologist regarding antibiotic therapy in acne. 1980 Acta Derm Venereol Suppl (Stockh) pmid:6451131
Kligman AM et al. Acne therapy with tretinoin in combination with antibiotics. 1975 Jan 27-29 Acta Derm Venereol Suppl (Stockh) pmid:130772
Valsecchi R and Cainelli T Gingival hyperplasia induced by erythromycin. 1992 Acta Derm. Venereol. pmid:1350410
Guin JD et al. Antibiotic sensitivity of comedonal Propionibacterium acnes. 1979 Acta Derm. Venereol. pmid:94223
Gudjónsson H Experiments to induce febrile Jarisch-Herxheimer reaction in syphilitic rabbits with penicillin and erythromycin. 1972 Acta Derm. Venereol. pmid:4118397