erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Mokhber-Dezfooli MR et al. | Effect of abomasal emptying rate on the apparent efficiency of colostral immunoglobulin G absorption in neonatal Holstein-Friesian calves. | 2012 | J. Dairy Sci. | pmid:22981576 |
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Gazzola S et al. | Assessment of tetracycline and erythromycin resistance transfer during sausage fermentation by culture-dependent and -independent methods. | 2012 | Food Microbiol. | pmid:22365347 |
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Shore EM and Yudin MH | Choice of antibiotic for group B streptococcus in women in labour based on antibiotic sensitivity testing. | 2012 | J Obstet Gynaecol Can | pmid:22385665 |
Pinto A et al. | 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. | 2012 | Org. Lett. | pmid:22519860 |
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Zhang W et al. | Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. | 2011 | Curr. Microbiol. | pmid:20924584 |
Hewer RC et al. | PKA and Epac synergistically inhibit smooth muscle cell proliferation. | 2011 | J. Mol. Cell. Cardiol. | pmid:20971121 |
Shang Y et al. | Dexamethasone protects airway epithelial cell line NCI-H292 against lipopolysaccharide induced endoplasmic reticulum stress and apoptosis. | 2011 | Chin. Med. J. | pmid:21362305 |
Pateron D et al. | Erythromycin infusion or gastric lavage for upper gastrointestinal bleeding: a multicenter randomized controlled trial. | 2011 | Ann Emerg Med | pmid:21333385 |
Cai XJ et al. | [Protective effects of erythromycin on human bronchial epithelial cells impaired by interleukin-4]. | 2011 | Zhonghua Yi Xue Za Zhi | pmid:22094097 |
Otsu K et al. | Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. | 2011 | Pharmacology | pmid:22116077 |
Nakashima R et al. | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. | 2011 | Nature | pmid:22121023 |
Abarzúa F et al. | [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. | 2011 | Rev Chilena Infectol | pmid:22052397 |
Song W et al. | Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. | 2011 | Int J Nanomedicine | pmid:22228990 |
Hiller NL et al. | Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. | 2011 | PLoS ONE | pmid:22205975 |
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Belousoff MJ et al. | Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21282615 |
Spigaglia P et al. | Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. | 2011 | Emerging Infect. Dis. | pmid:21291621 |
Huppertz A et al. | Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor of organic anion transporting peptides (OATP). | 2011 | J Magn Reson Imaging | pmid:21274983 |
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Ma S et al. | Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. | 2011 | Eur J Med Chem | pmid:21159410 |
DeDea L | Erythromycin for GI motility; sunscreens; enoxaparin in obesity. | 2011 | JAAPA | pmid:21850912 |
Maeda Y et al. | Comparison of minimum inhibitory concentration by broth microdilution testing versus standard disc diffusion testing in the detection of penicillin, erythromycin and ciprofloxacin resistance in viridans group streptococci. | 2011 | J. Med. Microbiol. | pmid:21852527 |
Chen Y et al. | Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions. | 2011 | Drug Metab. Dispos. | pmid:21835977 |
Ahmetagic A et al. | Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. | 2011 | Plasmid | pmid:21839110 |
Zhou L et al. | Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. | 2011 | Vaccine | pmid:21839135 |
Wu J et al. | Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination. | 2011 | Appl. Environ. Microbiol. | pmid:21841022 |
Raynes Greenow CH et al. | Antibiotics for ureaplasma in the vagina in pregnancy. | 2011 | Cochrane Database Syst Rev | pmid:21901685 |
Wunder DB et al. | Sorption of antibiotics to biofilm. | 2011 | Water Res. | pmid:21334040 |
Senthilkumaran S and Subramanian PT | Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. | 2011 | Indian Pediatr | pmid:22711153 |
Sugiyama E et al. | The use of 13C-erythromycin as an in vivo probe to evaluate CYP3A-mediated drug interactions in rats. | 2011 | J Pharm Sci | pmid:21618542 |
Qin X et al. | Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. | 2011 | Int. J. Antimicrob. Agents | pmid:21549571 |
Sigaroudinia MO and Quayle AR | Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. | 2011 | Surgeon | pmid:21550524 |
Szary NM et al. | Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. | 2011 | Scand. J. Gastroenterol. | pmid:21561232 |
Wei Z and Wang J | Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. | 2011 | Anal. Chim. Acta | pmid:21565301 |
Ren W and Markel DC | Emerging ideas: can erythromycin reduce the risk of aseptic loosening? | 2011 | Clin. Orthop. Relat. Res. | pmid:21584820 |
Torra S et al. | Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). | 2011 | Int J Obes (Lond) | pmid:20938444 |
Andini N and Nash KA | Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. | 2011 | FEMS Microbiol. Lett. | pmid:21718348 |
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Imperi M et al. | Invasive neonatal GBS infections from an area-based surveillance study in Italy. | 2011 | Clin. Microbiol. Infect. | pmid:21722258 |
Wan G et al. | Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. | 2011 | Cell. Signal. | pmid:21723942 |
Kalmokoff M et al. | Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. | 2011 | J. Appl. Microbiol. | pmid:21395944 |
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Boghigian BA et al. | Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. | 2011 | J. Ind. Microbiol. Biotechnol. | pmid:21487833 |
Miyashita N et al. | Community-acquired macrolide-resistant Mycoplasma pneumoniae pneumonia in patients more than 18 years of age. | 2011 | J. Infect. Chemother. | pmid:20676912 |
Chen I et al. | Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. | 2011 | J. Clin. Microbiol. | pmid:21068284 |
Spurling GK et al. | Antibiotics for bronchiolitis in children. | 2011 | Cochrane Database Syst Rev | pmid:21678346 |
Matsson EM et al. | Biliary excretion of ximelagatran and its metabolites and the influence of erythromycin following intraintestinal administration to healthy volunteers. | 2011 | J Clin Pharmacol | pmid:20663994 |
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Mikura S et al. | Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. | 2011 | Transl Res | pmid:21708354 |
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Del Grosso M et al. | Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. | 2011 | Antimicrob. Agents Chemother. | pmid:21502613 |
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