erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Mulholland S et al. Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. 2012 Cochrane Database Syst Rev pmid:22972079
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Wang L et al. Persistence of resistance to erythromycin and tetracycline in swine manure during simulated composting and lagoon treatments. 2012 Microb. Ecol. pmid:21811793
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Pinto A et al. 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. 2012 Org. Lett. pmid:22519860
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Lam HS and Ng PC Use of prokinetics in the preterm infant. 2011 Curr. Opin. Pediatr. pmid:21178622
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DeDea L Erythromycin for GI motility; sunscreens; enoxaparin in obesity. 2011 JAAPA pmid:21850912
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Senthilkumaran S and Subramanian PT Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. 2011 Indian Pediatr pmid:22711153
Sugiyama E et al. The use of 13C-erythromycin as an in vivo probe to evaluate CYP3A-mediated drug interactions in rats. 2011 J Pharm Sci pmid:21618542
Qin X et al. Two paediatric cases of skin and soft-tissue infections due to clindamycin-resistant Staphylococcus aureus carrying a plasmid-encoded vga(A) allelic variant for a putative efflux pump. 2011 Int. J. Antimicrob. Agents pmid:21549571
Sigaroudinia MO and Quayle AR Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. 2011 Surgeon pmid:21550524
Szary NM et al. Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. 2011 Scand. J. Gastroenterol. pmid:21561232
Wei Z and Wang J Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. 2011 Anal. Chim. Acta pmid:21565301
Ren W and Markel DC Emerging ideas: can erythromycin reduce the risk of aseptic loosening? 2011 Clin. Orthop. Relat. Res. pmid:21584820
Torra S et al. Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). 2011 Int J Obes (Lond) pmid:20938444
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