erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Li SL et al. | A single tube modified allele-specific-PCR for rapid detection of erythromycin-resistant Mycoplasma pneumoniae in Beijing. | 2012 | Chin. Med. J. | pmid:22931973 |
Nimgaonkar A et al. | Gastrointestinal dysmotility. | 2012 | Dig. Dis. Sci. | pmid:22038542 |
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Villaseñor-Sierra A et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010. | 2012 | Int. J. Infect. Dis. | pmid:22217469 |
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Blode H et al. | Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. | 2012 | Contraception | pmid:22445438 |
Kanazu T et al. | Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. | 2012 | Biopharm Drug Dispos | pmid:22447511 |
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Mehra T et al. | Treatment of severe acne with low-dose isotretinoin. | 2012 | Acta Derm. Venereol. | pmid:22377969 |
Ogawa W et al. | Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. | 2012 | Gene | pmid:22391093 |
Diacon AH et al. | Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22391540 |
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Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
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Hewer RC et al. | PKA and Epac synergistically inhibit smooth muscle cell proliferation. | 2011 | J. Mol. Cell. Cardiol. | pmid:20971121 |
Stang EM and White MC | On the macrocyclization of the erythromycin core: preorganization is not required. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21344559 |
Fessler AT et al. | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:20876371 |
Qin SS et al. | Antimicrobial resistance in Campylobacter coli isolated from pigs in two provinces of China. | 2011 | Int. J. Food Microbiol. | pmid:21349598 |
Song M et al. | Antibiotic susceptibility of Propionibacterium acnes isolated from acne vulgaris in Korea. | 2011 | J. Dermatol. | pmid:21352337 |
Liu BY et al. | Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole on photosynthetic apparatus in Selenastrum capricornutum. | 2011 | Ecotoxicol. Environ. Saf. | pmid:21353704 |
Crivellaro S et al. | Surveillance of methicillin-resistant Staphylococcus aureus isolated in Torino (northwest Italy). | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21353947 |
Ogungbenro K et al. | A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients. | 2011 | Pharm. Res. | pmid:20949310 |
Lubell Y et al. | Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. | 2011 | Trop. Med. Int. Health | pmid:21740488 |
Spigaglia P et al. | Multidrug resistance in European Clostridium difficile clinical isolates. | 2011 | J. Antimicrob. Chemother. | pmid:21771851 |
Lam HS and Ng PC | Use of prokinetics in the preterm infant. | 2011 | Curr. Opin. Pediatr. | pmid:21178622 |
Jupelli M et al. | Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life. | 2011 | Lab. Invest. | pmid:21769086 |
Clifford V et al. | Variation in erythromycin and clindamycin resistance patterns between New Zealand and Australian group B streptococcus isolates. | 2011 | Aust N Z J Obstet Gynaecol | pmid:21806568 |
Ma S et al. | Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. | 2011 | Eur J Med Chem | pmid:21159410 |
Nielsen EI et al. | Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization. | 2011 | Antimicrob. Agents Chemother. | pmid:21807983 |
Mak PJ et al. | Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. | 2011 | J. Am. Chem. Soc. | pmid:21207936 |
Ren GW et al. | Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. | 2011 | Foodborne Pathog. Dis. | pmid:21166562 |
Gardner L et al. | Photochemical control of bacterial signal processing using a light-activated erythromycin. | 2011 | Mol Biosyst | pmid:21785768 |
Srinivasan U et al. | Identification of a novel keyhole phenotype in double-disk diffusion assays of clindamycin-resistant erythromycin-sensitive strains of Streptococcus agalactiae. | 2011 | Microb. Drug Resist. | pmid:21166574 |
Khan NW et al. | Antimicrobial activity of erythromycin and clarithromycin against clinical isolates of Escherichia coli, Staphylococcus aureus, Klebsiella and Proteus by disc diffusion method. | 2011 | Pak J Pharm Sci | pmid:21190914 |
Wunder DB et al. | Sorption of antibiotics to biofilm. | 2011 | Water Res. | pmid:21334040 |
Ren W and Markel DC | Emerging ideas: can erythromycin reduce the risk of aseptic loosening? | 2011 | Clin. Orthop. Relat. Res. | pmid:21584820 |
Öberg AI et al. | β-Adrenergic inhibition of contractility in L6 skeletal muscle cells. | 2011 | PLoS ONE | pmid:21829455 |
Osman M and Ghosh SK | Semiparametric bayesian testing procedure for noninferiority trials with binary endpoints. | 2011 | J Biopharm Stat | pmid:21830923 |
Torra S et al. | Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). | 2011 | Int J Obes (Lond) | pmid:20938444 |
Baronsky J et al. | Perfusion calorimetry in the characterization of solvates forming isomorphic desolvates. | 2011 | Eur J Pharm Sci | pmid:21726637 |
Dixon-Woods M et al. | Providing the results of research to participants: a mixed-method study of the benefits and challenges of a consultative approach. | 2011 | Clin Trials | pmid:21730081 |
Akshay S et al. | Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. | 2011 | Antimicrob. Agents Chemother. | pmid:21730122 |
Li MJ et al. | High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. | 2011 | Analyst | pmid:20944848 |
Pannu J et al. | In vitro antibacterial activity of NB-003 against Propionibacterium acnes. | 2011 | Antimicrob. Agents Chemother. | pmid:21746943 |
Daram SR and Garretson R | Erythromycin is preferable to metoclopramide as a prokinetic in acute upper GI bleeding. | 2011 | Gastrointest. Endosc. | pmid:21704823 |
Ma X et al. | Novel C-4'' modified azithromycin analogs with remarkably enhanced activity against erythromycin-resistant Streptococcus pneumoniae: the synthesis and antimicrobial evaluation. | 2011 | Eur J Med Chem | pmid:21855183 |
Soehnlen MK et al. | In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method. | 2011 | J. Vet. Diagn. Invest. | pmid:21908288 |
Albarellos GA et al. | Pharmacokinetics of erythromycin after intravenous, intramuscular and oral administration to cats. | 2011 | Vet. J. | pmid:19854664 |
Brodesser S and Kolter T | Dihydroceramide desaturase inhibition by a cyclopropanated dihydroceramide analog in cultured keratinocytes. | 2011 | J Lipids | pmid:21490810 |
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Kalmokoff M et al. | Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. | 2011 | J. Appl. Microbiol. | pmid:21395944 |
Juntunen P et al. | Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. | 2011 | Vet. Microbiol. | pmid:21397412 |
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Boghigian BA et al. | Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. | 2011 | J. Ind. Microbiol. Biotechnol. | pmid:21487833 |
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Zou X et al. | An assessment of seed quality on erythromycin production by recombinant Saccharopolyspora erythraea strain. | 2011 | Bioresour. Technol. | pmid:21134745 |
Palmieri C et al. | Different genetic elements carrying the tet(W) gene in two human clinical isolates of Streptococcus suis. | 2011 | Antimicrob. Agents Chemother. | pmid:21115784 |
Jorgensen JH et al. | Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. | 2011 | J. Clin. Microbiol. | pmid:21697321 |
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Gannon M et al. | Clinical inquiries. Which oral antibiotics are best for acne? | 2011 | J Fam Pract | pmid:21544278 |
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Chia HY et al. | Follicular spicules associated with Propionibacterium acnes in response to erythromycin. | 2011 | J. Dermatol. | pmid:21544949 |
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Gray KL et al. | The outpatient institutional antibiogram does not accurately reflect the susceptibility of prepartum group B streptococcal isolates to erythromycin and clindamycin. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21982562 |
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Meinertz JR et al. | Chronic toxicity of erythromycin thiocyanate to Daphnia magna in a flow-through, continuous exposure test system. | 2011 | Bull Environ Contam Toxicol | pmid:21984684 |
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