erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Kjeldgaard J et al. Residual antibiotics disrupt meat fermentation and increase risk of infection. 2012 MBio pmid:22930338
Sakatis MZ et al. Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. 2012 Chem. Res. Toxicol. pmid:22931300
Li SL et al. A single tube modified allele-specific-PCR for rapid detection of erythromycin-resistant Mycoplasma pneumoniae in Beijing. 2012 Chin. Med. J. pmid:22931973
Nimgaonkar A et al. Gastrointestinal dysmotility. 2012 Dig. Dis. Sci. pmid:22038542
Fazeli M et al. Erythromycin enhances abomasal emptying in healthy unweaned lambs as shown by acetaminophen absorption test. 2012 J. Vet. Pharmacol. Ther. pmid:22066489
Reutenauer-Patte J et al. Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways. 2012 Am. J. Pathol. pmid:22192627
Villaseñor-Sierra A et al. Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010. 2012 Int. J. Infect. Dis. pmid:22217469
Luangtongkum T et al. Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. 2012 Antimicrob. Agents Chemother. pmid:22183170
Blode H et al. Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. 2012 Contraception pmid:22445438
Kanazu T et al. Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. 2012 Biopharm Drug Dispos pmid:22447511
Liu X et al. Potentials and mechanisms of genotoxicity of six pharmaceuticals frequently detected in freshwater environment. 2012 Toxicol. Lett. pmid:22450446
Mehra T et al. Treatment of severe acne with low-dose isotretinoin. 2012 Acta Derm. Venereol. pmid:22377969
Ogawa W et al. Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. 2012 Gene pmid:22391093
Diacon AH et al. Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. 2012 Antimicrob. Agents Chemother. pmid:22391540
Peano C et al. Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain. 2012 Microb. Cell Fact. pmid:22401291
Yuzawa S et al. Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases. 2012 Biochemistry pmid:22509729
El-Adawy H et al. Determination of antimicrobial sensitivities of Campylobacter jejuni isolated from commercial turkey farms in Germany. 2012 Avian Dis. pmid:23397839
Cannon JA et al. Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections. 2012 Dis. Colon Rectum pmid:23044677
Kaul M et al. A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization. 2012 J. Med. Chem. pmid:23050700
Du Plessis LH et al. In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum. 2012 J. Antibiot. pmid:23093037
Henningsen E and Bygum A Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. 2011 Sep-Oct Pediatr Dermatol pmid:21895758
Ezhova NM et al. [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. 2011 Nov-Dec Prikl. Biokhim. Mikrobiol. pmid:22288199
Zhang W et al. Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. 2011 Curr. Microbiol. pmid:20924584
Hewer RC et al. PKA and Epac synergistically inhibit smooth muscle cell proliferation. 2011 J. Mol. Cell. Cardiol. pmid:20971121
Stang EM and White MC On the macrocyclization of the erythromycin core: preorganization is not required. 2011 Angew. Chem. Int. Ed. Engl. pmid:21344559
Fessler AT et al. Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. 2011 Antimicrob. Agents Chemother. pmid:20876371
Qin SS et al. Antimicrobial resistance in Campylobacter coli isolated from pigs in two provinces of China. 2011 Int. J. Food Microbiol. pmid:21349598
Song M et al. Antibiotic susceptibility of Propionibacterium acnes isolated from acne vulgaris in Korea. 2011 J. Dermatol. pmid:21352337
Liu BY et al. Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole on photosynthetic apparatus in Selenastrum capricornutum. 2011 Ecotoxicol. Environ. Saf. pmid:21353704
Crivellaro S et al. Surveillance of methicillin-resistant Staphylococcus aureus isolated in Torino (northwest Italy). 2011 Diagn. Microbiol. Infect. Dis. pmid:21353947
Ogungbenro K et al. A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients. 2011 Pharm. Res. pmid:20949310
Lubell Y et al. Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. 2011 Trop. Med. Int. Health pmid:21740488
Spigaglia P et al. Multidrug resistance in European Clostridium difficile clinical isolates. 2011 J. Antimicrob. Chemother. pmid:21771851
Lam HS and Ng PC Use of prokinetics in the preterm infant. 2011 Curr. Opin. Pediatr. pmid:21178622
Jupelli M et al. Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life. 2011 Lab. Invest. pmid:21769086
Clifford V et al. Variation in erythromycin and clindamycin resistance patterns between New Zealand and Australian group B streptococcus isolates. 2011 Aust N Z J Obstet Gynaecol pmid:21806568
Ma S et al. Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. 2011 Eur J Med Chem pmid:21159410
Nielsen EI et al. Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization. 2011 Antimicrob. Agents Chemother. pmid:21807983
Mak PJ et al. Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. 2011 J. Am. Chem. Soc. pmid:21207936
Ren GW et al. Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. 2011 Foodborne Pathog. Dis. pmid:21166562
Gardner L et al. Photochemical control of bacterial signal processing using a light-activated erythromycin. 2011 Mol Biosyst pmid:21785768
Srinivasan U et al. Identification of a novel keyhole phenotype in double-disk diffusion assays of clindamycin-resistant erythromycin-sensitive strains of Streptococcus agalactiae. 2011 Microb. Drug Resist. pmid:21166574
Khan NW et al. Antimicrobial activity of erythromycin and clarithromycin against clinical isolates of Escherichia coli, Staphylococcus aureus, Klebsiella and Proteus by disc diffusion method. 2011 Pak J Pharm Sci pmid:21190914
Wunder DB et al. Sorption of antibiotics to biofilm. 2011 Water Res. pmid:21334040
Ren W and Markel DC Emerging ideas: can erythromycin reduce the risk of aseptic loosening? 2011 Clin. Orthop. Relat. Res. pmid:21584820
Öberg AI et al. β-Adrenergic inhibition of contractility in L6 skeletal muscle cells. 2011 PLoS ONE pmid:21829455
Osman M and Ghosh SK Semiparametric bayesian testing procedure for noninferiority trials with binary endpoints. 2011 J Biopharm Stat pmid:21830923
Torra S et al. Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). 2011 Int J Obes (Lond) pmid:20938444
Baronsky J et al. Perfusion calorimetry in the characterization of solvates forming isomorphic desolvates. 2011 Eur J Pharm Sci pmid:21726637
Dixon-Woods M et al. Providing the results of research to participants: a mixed-method study of the benefits and challenges of a consultative approach. 2011 Clin Trials pmid:21730081
Akshay S et al. Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. 2011 Antimicrob. Agents Chemother. pmid:21730122
Li MJ et al. High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. 2011 Analyst pmid:20944848
Pannu J et al. In vitro antibacterial activity of NB-003 against Propionibacterium acnes. 2011 Antimicrob. Agents Chemother. pmid:21746943
Daram SR and Garretson R Erythromycin is preferable to metoclopramide as a prokinetic in acute upper GI bleeding. 2011 Gastrointest. Endosc. pmid:21704823
Ma X et al. Novel C-4'' modified azithromycin analogs with remarkably enhanced activity against erythromycin-resistant Streptococcus pneumoniae: the synthesis and antimicrobial evaluation. 2011 Eur J Med Chem pmid:21855183
Soehnlen MK et al. In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method. 2011 J. Vet. Diagn. Invest. pmid:21908288
Albarellos GA et al. Pharmacokinetics of erythromycin after intravenous, intramuscular and oral administration to cats. 2011 Vet. J. pmid:19854664
Brodesser S and Kolter T Dihydroceramide desaturase inhibition by a cyclopropanated dihydroceramide analog in cultured keratinocytes. 2011 J Lipids pmid:21490810
Motoyama M et al. Residues of pharmaceutical products in recycled organic manure produced from sewage sludge and solid waste from livestock and relationship to their fermentation level. 2011 Chemosphere pmid:21570103
Kalmokoff M et al. Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. 2011 J. Appl. Microbiol. pmid:21395944
Juntunen P et al. Longitudinal on-farm study of the development of antimicrobial resistance in Campylobacter coli from pigs before and after danofloxacin and tylosin treatments. 2011 Vet. Microbiol. pmid:21397412
Haenni M et al. ermB-mediated erythromycin resistance in Streptococcus uberis from bovine mastitis. 2011 Vet. J. pmid:20667752
Boghigian BA et al. Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess. 2011 J. Ind. Microbiol. Biotechnol. pmid:21487833
Chen I et al. Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. 2011 J. Clin. Microbiol. pmid:21068284
Bilk S et al. Antimicrobial susceptibilities and occurrence of resistance genes in bovine Helcococcus ovis isolates. 2011 Vet. Microbiol. pmid:21131144
Zou X et al. An assessment of seed quality on erythromycin production by recombinant Saccharopolyspora erythraea strain. 2011 Bioresour. Technol. pmid:21134745
Palmieri C et al. Different genetic elements carrying the tet(W) gene in two human clinical isolates of Streptococcus suis. 2011 Antimicrob. Agents Chemother. pmid:21115784
Jorgensen JH et al. Collaborative evaluation of an erythromycin-clindamycin combination well for detection of inducible clindamycin resistance in beta-hemolytic streptococci by use of the CLSI broth microdilution method. 2011 J. Clin. Microbiol. pmid:21697321
Mansi Y et al. Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants. 2011 Neonatology pmid:21701222
Ng PC Erythromycin as a prokinetic agent in newborns--useful or doubtful. Commentary on Y. Mansi et al.: Randomized controlled trial of a high dose of oral erythromycin for the treatment of feeding intolerance in preterm infants (Neonatology 2011;100:290-294). 2011 Neonatology pmid:21701224
Sarig H et al. Functional studies of cochleate assemblies of an oligo-acyl-lysyl with lipid mixtures for combating bacterial multidrug resistance. 2011 FASEB J. pmid:21676947
Shingate BB et al. Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain. 2011 Eur J Med Chem pmid:21664730
Hoa PT et al. Antibiotic contamination and occurrence of antibiotic-resistant bacteria in aquatic environments of northern Vietnam. 2011 Sci. Total Environ. pmid:21669325
Joao EC et al. Group B Streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile. 2011 Scand. J. Infect. Dis. pmid:21671824
Fry DE Colon preparation and surgical site infection. 2011 Am. J. Surg. pmid:21429471
de Morais e Silva FA et al. Rosacea fulminans in pregnancy with ocular perforation. 2011 J Dtsch Dermatol Ges pmid:21366860
Feneran AN et al. Retinoid plus antimicrobial combination treatments for acne. 2011 Clin Cosmet Investig Dermatol pmid:21760743
Mueller DH et al. Constraints to implementing the Essential Health Package in Malawi. 2011 PLoS ONE pmid:21695115
Ma L et al. Green fluorescent protein labeling of Listeria, Salmonella, and Escherichia coli O157:H7 for safety-related studies. 2011 PLoS ONE pmid:21483738
Xiong L et al. Lignans and neolignans from Sinocalamus affinis and their absolute configurations. 2011 J. Nat. Prod. pmid:21469695
Boghigian BA et al. Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. 2011 Biotechnol. Bioeng. pmid:21337322
Dow GS et al. Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice. 2011 Malar. J. pmid:21645370
Piccialli V et al. Isolation of a bis-iodurated tetra-THF as a trace product from the oxidation of squalene with RuOâ‚„ and its double ring expansion to a novel bis-THF-bis-THP compound. 2011 Molecules pmid:21709619
Zhang Z et al. Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:21498135
Del Grosso M et al. Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. 2011 Antimicrob. Agents Chemother. pmid:21502613
Loreto ES et al. In vitro susceptibility of Pythium insidiosum to macrolides and tetracycline antibiotics. 2011 Antimicrob. Agents Chemother. pmid:21537028
Nakamura PA et al. Antimicrobial resistance profiles and genetic characterisation of macrolide resistant isolates of Streptococcus agalactiae. 2011 Mem. Inst. Oswaldo Cruz pmid:21537668
Ozkok IP et al. Respirometric assessment of substrate binding by antibiotics in peptone biodegradation. 2011 J Environ Sci Health A Tox Hazard Subst Environ Eng pmid:22029701
Shaala LA et al. Brominated arginine-derived alkaloids from the red sea sponge Suberea mollis. 2011 J. Nat. Prod. pmid:21542602
Justa RF et al. Bacillary angiomatosis in HIV-positive patient from Northeastern Brazil: a case report. 2011 Rev. Soc. Bras. Med. Trop. pmid:22031085
Zhao DL et al. Characterization of a cryptic plasmid pSM429 and its application for heterologous expression in psychrophilic Pseudoalteromonas. 2011 Microb. Cell Fact. pmid:21542941
Jakeman DL and Sadeghi-Khomami A A β-(1,2)-glycosynthase and an attempted selection method for the directed evolution of glycosynthases. 2011 Biochemistry pmid:22035228
Gannon M et al. Clinical inquiries. Which oral antibiotics are best for acne? 2011 J Fam Pract pmid:21544278
Zhou Y et al. [Detection and the antibiotic susceptibility analysis of mycoplasma and chlamydia in urogenital tract infections of 327 cases patients with tubal infertility]. 2011 Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi pmid:21977592
Chia HY et al. Follicular spicules associated with Propionibacterium acnes in response to erythromycin. 2011 J. Dermatol. pmid:21544949
Farkas B et al. [Frequency and antibiotic resistance of Ureaplasma urealyticum and Mycoplasma hominis in genital samples of sexually active individuals]. 2011 Orv Hetil pmid:21979223
Gray KL et al. The outpatient institutional antibiogram does not accurately reflect the susceptibility of prepartum group B streptococcal isolates to erythromycin and clindamycin. 2011 Diagn. Microbiol. Infect. Dis. pmid:21982562
Sedighi I et al. Nasal carriage of methicillin resistant Staphylococcus aureus and their antibiotic susceptibility patterns in children attending day-care centers. 2011 Acta Microbiol Immunol Hung pmid:21983324
Meinertz JR et al. Chronic toxicity of erythromycin thiocyanate to Daphnia magna in a flow-through, continuous exposure test system. 2011 Bull Environ Contam Toxicol pmid:21984684
Bansal BK et al. Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health. 2011 Trop Anim Health Prod pmid:20844949