erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Kudoh S [Pathophysiology of diffuse panbronchiolitis and progress of the therapy]. 1996 Nihon Kyobu Shikkan Gakkai Zasshi pmid:9216178
Tenson T et al. Erythromycin resistance peptides selected from random peptide libraries. 1997 J. Biol. Chem. pmid:9211885
Itoh Z Motilin and clinical application. 1997 Peptides pmid:9210180
Kluger MT Erythromycin--a pro-kinetic and pro-arrhythmogenic agent. 1997 Anaesth Intensive Care pmid:9209631
Nakata K et al. [Suppressive effect of clarithromycin on the production of verotoxin by E. coli O157]. 1997 Kansenshogaku Zasshi pmid:9209125
Nakamura A [Prevalence of antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in a children's hospital]. 1997 Kansenshogaku Zasshi pmid:9209123
Vagliasindi M Use of flurythromycin ethylsuccinate in infections of lower airways due to sensitive germs: multicenter comparative study with clarithromycin. 1997 Int J Clin Pharmacol Ther pmid:9208340
Lagasse JP et al. [Acute reversible pan-dysautonomia: effect of erythromycin on gastrointestinal involvement]. 1997 Gastroenterol. Clin. Biol. pmid:9208000
Gleason PP et al. Medical outcomes and antimicrobial costs with the use of the American Thoracic Society guidelines for outpatients with community-acquired pneumonia. 1997 JAMA pmid:9207335
Rampe D and Murawsky MK Blockade of the human cardiac K+ channel Kv1.5 by the antibiotic erythromycin. 1997 Naunyn Schmiedebergs Arch. Pharmacol. pmid:9205959
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Rosser EJ German shepherd dog pyoderma: a prospective study of 12 dogs. 1997 Jul-Aug J Am Anim Hosp Assoc pmid:9204474
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Kabir I et al. Erythromycin and trimethoprim-sulphamethoxazole in the treatment of cholera in children. 1996 J Diarrhoeal Dis Res pmid:9203786
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Son R et al. Antibiotic resistance and plasmid profile of Aeromonas hydrophila isolates from cultured fish, Telapia (Telapia mossambica). 1997 Lett. Appl. Microbiol. pmid:9203404
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Shimada T et al. Cytochrome P450-dependent drug oxidation activities in liver microsomes of various animal species including rats, guinea pigs, dogs, monkeys, and humans. 1997 Arch. Toxicol. pmid:9195021
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Reines HD et al. Use of standard colon preparation in elective colectomy for carcinoma of the colon. 1977 Nov-Dec Rev Surg pmid:918536
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Roe DE et al. Mobile rRNA methylase genes coding for erythromycin resistance in Actinobacillus actinomycetemcomitans. 1996 J. Antimicrob. Chemother. pmid:9182102
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Resnick J et al. Delayed gastric emptying and postoperative ileus after nongastric abdominal surgery: part II. 1997 Am. J. Gastroenterol. pmid:9177505
Young H et al. Azithromycin and erythromycin resistant Neisseria gonorrhoeae following treatment with azithromycin. 1997 Int J STD AIDS pmid:9175650
Rybak MJ et al. Pharmacodynamics of RP 59500 (quinupristin-dalfopristin) administered by intermittent versus continuous infusion against Staphylococcus aureus-infected fibrin-platelet clots in an in vitro infection model. 1997 Antimicrob. Agents Chemother. pmid:9174199
Gibert Agulló A et al. [Generalized acute exanthematous pustulosis: two case reports]. 1997 An. Esp. Pediatr. pmid:9173852
Berg-Candolfi M et al. Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression. 1996 Xenobiotica pmid:9173679
Piérard GE [Pharma Clinics. Drug of the month. Benzamycin, an up-date on topical treatment of acne]. 1997 Rev Med Liege pmid:9173479
Koch B et al. Construction of specific erythromycin resistance mutations in the temperate lactococcal bacteriophage TP901-1 and their use in studies of phage biology. 1997 Appl. Environ. Microbiol. pmid:9172365
Leloup L et al. Single-crossover integration in the Lactobacillus sake chromosome and insertional inactivation of the ptsI and lacL genes. 1997 Appl. Environ. Microbiol. pmid:9172327
Somkuti GA et al. Molecular properties of the erythromycin resistance plasmid pPV141 from Staphylococcus chromogenes. 1997 Plasmid pmid:9169203
Scalabrino G et al. Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord. 1997 Exp. Neurol. pmid:9168827
Lin JC and Quasny HA QT prolongation and development of torsades de pointes with the concomitant administration of oral erythromycin base and quinidine. 1997 May-Jun Pharmacotherapy pmid:9165570
Cheng CL et al. Steady-state pharmacokinetics of delavirdine in HIV-positive patients: effect on erythromycin breath test. 1997 Clin. Pharmacol. Ther. pmid:9164415
Yanagihara K et al. [Efficacy of erythromycin inhalation in chronic respiratory infection caused by Pseudomonas aeruginosa]. 1997 Kansenshogaku Zasshi pmid:9164089
Sugihara E Effect of macrolide antibiotics on neutrophil function in human peripheral blood. 1997 Kansenshogaku Zasshi pmid:9164088
Hessler PE et al. Isolation of isoflavones from soy-based fermentations of the erythromycin-producing bacterium Saccharopolyspora erythraea. 1997 Appl. Microbiol. Biotechnol. pmid:9163954
Heaton MP and Handwerger S Conjugative mobilization of a vancomycin resistance plasmid by a putative Enterococcus faecium sex pheromone response plasmid. 1995 Microb. Drug Resist. pmid:9158753
Matsuhashi M et al. Cellular signals regulating antibiotic sensitivities of bacteria. 1996 Microb. Drug Resist. pmid:9158728
Mitsuyama T et al. Inhibition by erythromycin of human pulmonary artery endothelial cell injury induced by human neutrophils. 1997 Respiration pmid:9154672
Carroll KC et al. Susceptibility of beta-hemolytic streptococci to nine antimicrobial agents among four medical centers in Salt Lake City, Utah, USA. 1997 Diagn. Microbiol. Infect. Dis. pmid:9154408