erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ridley EJ and Davies AR | Practicalities of nutrition support in the intensive care unit: the usefulness of gastric residual volume and prokinetic agents with enteral nutrition. | 2011 | Nutrition | pmid:21295944 |
Nguyen NQ et al. | Plasma erythromycin concentrations predict feeding outcomes in critically ill patients with feed intolerance. | 2011 | Crit. Care Med. | pmid:21297459 |
Thenmozhi R et al. | Characterization of biofilms in different clinical M serotypes of Streptococcus pyogenes. | 2011 | J. Basic Microbiol. | pmid:21298675 |
Yuan H et al. | [The effect of erythromycin on transforming growth factor-β(1) and secretory leukocyte proteinase inhibitor in a rat model of chronic obstructive pulmonary disease]. | 2011 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:22041779 |
Vadlapatla RK et al. | Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin. | 2011 | Int J Pharm | pmid:21864659 |
Lubell Y et al. | Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. | 2011 | Trop. Med. Int. Health | pmid:21740488 |
Spigaglia P et al. | Multidrug resistance in European Clostridium difficile clinical isolates. | 2011 | J. Antimicrob. Chemother. | pmid:21771851 |
RodrÃguez C et al. | [Resistance phenotypes and genotypes of Streptococcus pyogenes clinical isolates in Chile over a 10-year period]. | 2011 | Rev Med Chil | pmid:22215392 |
Lee HY et al. | Improved precursor-directed biosynthesis in E. coli via directed evolution. | 2011 | J. Antibiot. | pmid:21081955 |
Maezono H et al. | Antibiofilm effects of azithromycin and erythromycin on Porphyromonas gingivalis. | 2011 | Antimicrob. Agents Chemother. | pmid:21911560 |
Lehtopolku M et al. | Ribosomal mutations as the main cause of macrolide resistance in Campylobacter jejuni and Campylobacter coli. | 2011 | Antimicrob. Agents Chemother. | pmid:21911571 |
Drago L et al. | Macrolide resistance and in vitro selection of resistance to antibiotics in Lactobacillus isolates. | 2011 | J. Microbiol. | pmid:21887650 |
Liu K et al. | Direct entry to erythronolides via a cyclic bis[allene]. | 2011 | J. Am. Chem. Soc. | pmid:21894913 |
Bosnjakovic A et al. | Poly(amidoamine) dendrimer-erythromycin conjugates for drug delivery to macrophages involved in periprosthetic inflammation. | 2011 | Nanomedicine | pmid:21059404 |
Bonofiglio L et al. | Dissemination of an erythromycin-resistant penicillin-nonsusceptible Streptococcus pneumoniae Poland(6B)-20 clone in Argentina. | 2011 | Microb. Drug Resist. | pmid:21128835 |
Zanoni RG et al. | Occurrence of Helicobacter pullorum in turkeys. | 2011 | Vet. Microbiol. | pmid:21144678 |
Panigaj M et al. | Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. | 2011 | PLoS ONE | pmid:21912705 |
Zaed AM and Sutherland A | Total synthesis of clavaminol A, C and H. | 2011 | Org. Biomol. Chem. | pmid:21879135 |
Taillon MP et al. | Potentially new isobaric metabolite of fluvastatin observed by LC-MS/MS during incurred sample analysis. | 2011 | Bioanalysis | pmid:21877892 |
Koulnis M et al. | Negative autoregulation by Fas stabilizes adult erythropoiesis and accelerates its stress response. | 2011 | PLoS ONE | pmid:21760888 |
Serisier DJ and Martin ML | Long-term, low-dose erythromycin in bronchiectasis subjects with frequent infective exacerbations. | 2011 | Respir Med | pmid:21367595 |
Almofti YA et al. | Impact of erythromycin resistance on the virulence properties and fitness of Campylobacter jejuni. | 2011 | Microb. Pathog. | pmid:21377522 |
Luo DQ et al. | In vitro activities of erythromycin, tetracycline and levofloxacin alone and in dual combinations against ureaplasma spp. | 2011 | Chemotherapy | pmid:21430380 |
Yongsheng J et al. | Antitumor activity of erythromycin on human neuroblastoma cell line (SH-SY5Y). | 2011 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:21336720 |
Pérez-Trallero E et al. | In vitro activities of retapamulin and 16 other antimicrobial agents against recently obtained Streptococcus pyogenes isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:21343452 |
Filić D et al. | Crystal structure and physicochemical properties of crystalline form of 2'-O-{3-[(7-chloro-4-quinolinyl)amino]propyl}-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A. | 2011 | J Pharm Sci | pmid:21394721 |
Wu JC and Sung JJ | Pharmacologic therapy for nonvariceal upper gastrointestinal bleeding. | 2011 | Gastrointest. Endosc. Clin. N. Am. | pmid:21944417 |
Kovacs TO and Jensen DM | Endoscopic therapy for severe ulcer bleeding. | 2011 | Gastrointest. Endosc. Clin. N. Am. | pmid:21944418 |
Ozkok IP et al. | Respirometric assessment of substrate binding by antibiotics in peptone biodegradation. | 2011 | J Environ Sci Health A Tox Hazard Subst Environ Eng | pmid:22029701 |
Justa RF et al. | Bacillary angiomatosis in HIV-positive patient from Northeastern Brazil: a case report. | 2011 | Rev. Soc. Bras. Med. Trop. | pmid:22031085 |
Tilmant K et al. | Comparison of a genomic and a multiplex cell imaging approach for the detection of phospholipidosis. | 2011 | Toxicol In Vitro | pmid:21515356 |
Ma X and Ma S | Significant breakthroughs in search for anti-infectious agents derived from erythromycin A. | 2011 | Curr. Med. Chem. | pmid:21517774 |
Boecxstaens V et al. | Modulation of the postprandial acid and bile pockets at the gastro-oesophageal junction by drugs that affect gastric motility. | 2011 | Aliment. Pharmacol. Ther. | pmid:21517922 |
Sugawara A et al. | Novel 12-membered non-antibiotic macrolides from erythromycin A; EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21524580 |
Cong C et al. | Synthesis and antibacterial activity of novel 4″-O-benzimidazolyl clarithromycin derivatives. | 2011 | Eur J Med Chem | pmid:21524827 |
Bansal BK et al. | Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health. | 2011 | Trop Anim Health Prod | pmid:20844949 |
Park HH et al. | The effect of macrolides on myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. | 2010 Sep-Oct | Am J Rhinol Allergy | pmid:21244734 |
Luiz DB et al. | Identification of degradation products of erythromycin A arising from ozone and advanced oxidation process treatment. | 2010 Sep-Oct | Water Environ. Res. | pmid:20942335 |
Al-Talib HI et al. | Methicillin-resistant Staphylococcus aureus nosocomial infection trends in Hospital Universiti Sains Malaysia during 2002-2007. | 2010 Sep-Oct | Ann Saudi Med | pmid:20697171 |
Murray MA et al. | Ocular bacillary angiomatosis in an immunocompromised man. | 2010 Sep-Oct | Ophthal Plast Reconstr Surg | pmid:20683276 |
Taneja N et al. | Emergence of tetracycline resistance in Vibrio cholerae O1 biotype El Tor serotype Ogawa from north India. | 2010 Oct-Dec | Indian J Pathol Microbiol | pmid:21045454 |
Dutil M | Benzoyl peroxide: enhancing antibiotic efficacy in acne management. | 2010 Nov-Dec | Skin Therapy Lett. | pmid:21076800 |
Levin TT et al. | Case report: delirium due to a diltiazem-fentanyl CYP3A4 drug interaction. | 2010 Nov-Dec | Gen Hosp Psychiatry | pmid:21112467 |
Bornstein E et al. | Photodamage to multidrug-resistant gram-positive and gram-negative bacteria by 870 nm/930 nm light potentiates erythromycin, tetracycline and ciprofloxacin. | 2010 May-Jun | Photochem. Photobiol. | pmid:20408973 |
Taylor SJ et al. | Treating delayed gastric emptying in critical illness: metoclopramide, erythromycin, and bedside (cortrak) nasointestinal tube placement. | 2010 May-Jun | JPEN J Parenter Enteral Nutr | pmid:20467010 |
Zhang LX et al. | Febrile ulceronecrotic Mucha-Habermann's disease with pulmonary involvement. | 2010 May-Jun | Pediatr Dermatol | pmid:20609148 |
Vorster M et al. | Erythromycin as an alternative to reduce interfering extra-cardiac activity in myocardial perfusion imaging. | 2010 May-Jun | Cardiovasc J Afr | pmid:20532452 |
Poulard F et al. | Impact of not measuring residual gastric volume in mechanically ventilated patients receiving early enteral feeding: a prospective before-after study. | 2010 Mar-Apr | JPEN J Parenter Enteral Nutr | pmid:19861528 |
Torrelo A et al. | Extensive comedonal and cystic acne in Patau syndrome. | 2010 Mar-Apr | Pediatr Dermatol | pmid:20537076 |
Armangil D et al. | Maternal pertussis is hazardous for a newborn: a case report. | 2010 Mar-Apr | Turk. J. Pediatr. | pmid:20560262 |
Tempera G et al. | In vitro activity of cefditoren versus other antibiotics against S. pneumoniae clinical strains isolated in Italy. | 2010 Jul-Sep | Int J Immunopathol Pharmacol | pmid:20943054 |
Pal N et al. | Detection of inducible clindamycin resistance among Staphylococcal isolates from different clinical specimens in western India. | 2010 Jul-Sep | J Postgrad Med | pmid:20739762 |
Darling EK and McDonald H | A meta-analysis of the efficacy of ocular prophylactic agents used for the prevention of gonococcal and chlamydial ophthalmia neonatorum. | 2010 Jul-Aug | J Midwifery Womens Health | pmid:20630358 |
Smith G | Differential diagnosis of red eye. | 2010 Jul-Aug | Pediatr Nurs | pmid:20860262 |
Dorobăţ OM et al. | [Antibiotic resistance of Gram-positive cocci isolated in 2008]. | 2010 Apr-Jun | Bacteriol Virusol Parazitol Epidemiol | pmid:21553473 |
Pană M et al. | [Study of Streptococcus pneumoniae strains resistant to antibiotics analyzed at "Cantacuzino" NIRDMI during 2006-2008]. | 2010 Apr-Jun | Bacteriol Virusol Parazitol Epidemiol | pmid:21553474 |
Nica M et al. | [Bacterial strains isolated from systemic infections and reported for evaluation and antibiotic resistance surveillance by the "Dr. Victor BabeÅŸ" Clinical Hospital for Infectious and Tropical Diseases, Bucharest]. | 2010 Apr-Jun | Bacteriol Virusol Parazitol Epidemiol | pmid:21553481 |
Bhaduri S and Montford D | Paromomycin treatment of recalcitrant Trichomonas vaginalis. | 2010 | Int J STD AIDS | pmid:20852211 |
Parker DL et al. | Elevated International Normalized Ratio associated with concurrent use of ophthalmic erythromycin and warfarin. | 2010 | Am J Health Syst Pharm | pmid:20044367 |
Omar SH et al. | Sub-antibiotic doses of erythromycin as a prokinetic in abdominal surgeries: reviving the old. | 2010 | J Egypt Soc Parasitol | pmid:21268547 |
Mohammadizadeh M et al. | Efficacy of prophylactic oral erythromycin to improve enteral feeding tolerance in preterm infants: a randomised controlled study. | 2010 | Singapore Med J | pmid:21221501 |
Xie L et al. | [Efficacy of low-dose oral erythromycin as an adjuvant therapy for cytomegalovirus infection]. | 2010 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:20199738 |
Mnif H et al. | [Bacillary angiomatosis]. | 2010 | Ann Dermatol Venereol | pmid:20227575 |
Nam G et al. | Synthesis and antibacterial activity of new 9-O-arylpropenyloxime ketolides. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20338761 |
Bowling JE et al. | Detection of inducible clindamycin resistance in beta-hemolytic streptococci by using the CLSI broth microdilution test and erythromycin-clindamycin combinations. | 2010 | J. Clin. Microbiol. | pmid:20392918 |
Vellinga D et al. | A string of pearls. | 2010 | J. Pediatr. | pmid:20394941 |
Dib JR et al. | First report of linear megaplasmids in the genus Micrococcus. | 2010 | Plasmid | pmid:19850076 |
Ma C et al. | Synthesis and antibacterial activity of novel 11,12-cyclic carbonate azithromycin 4''-O-carbamate derivatives. | 2010 | J. Antibiot. | pmid:19911029 |
Aslam M et al. | Characterization of antimicrobial resistance in Enterococcus spp. recovered from a commercial beef processing plant. | 2010 | Foodborne Pathog. Dis. | pmid:19911933 |
Zavadska D et al. | Macrolide resistance in group A beta haemolytic Streptococcus isolated from outpatient children in Latvia. | 2010 | APMIS | pmid:20477812 |
Lizier M et al. | Comparison of expression vectors in Lactobacillus reuteri strains. | 2010 | FEMS Microbiol. Lett. | pmid:20455948 |
Jarrett R et al. | Differing obstetric outcomes of rosacea fulminans in pregnancy: report of three cases with review of pathogenesis and management. | 2010 | Clin. Exp. Dermatol. | pmid:20456381 |
Olender A and Niemcewicz M | Macrolide, lincosamide, and streptogramin B-constitutive-type resistance in Corynebacterium pseudodiphtheriticum isolated from upper respiratory tract specimens. | 2010 | Microb. Drug Resist. | pmid:20438346 |
Pérez-Trallero E et al. | Antimicrobial resistance among respiratory pathogens in Spain: latest data and changes over 11 years (1996-1997 to 2006-2007). | 2010 | Antimicrob. Agents Chemother. | pmid:20439616 |
Useglio M et al. | TDP-L-megosamine biosynthesis pathway elucidation and megalomicin a production in Escherichia coli. | 2010 | Appl. Environ. Microbiol. | pmid:20418422 |
Lowe R et al. | Predicting phospholipidosis using machine learning. | 2010 | Mol. Pharm. | pmid:20799726 |
Liu Y et al. | 9-Dihydroerythromycins as non-antibiotic motilin receptor agonists. | 2010 | Bioorg. Med. Chem. Lett. | pmid:20801039 |
Qi Y et al. | Synthesis and antibacterial activity of novel 4''-O-carbamoyl erythromycin-A derivatives. | 2010 | Arch. Pharm. (Weinheim) | pmid:20803622 |
Jung H and Lee NY | [Evaluation of MicroScan Synergies plus Positive Combo 3 Panels for identification and antimicrobial susceptibility testing of Staphylococcus aureus and Enterococcus species]. | 2010 | Korean J Lab Med | pmid:20805709 |
Agrawal V et al. | Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase. | 2010 | Pharmacogenet. Genomics | pmid:20697309 |
Allas U and Tenson T | A method for selecting cis-acting regulatory sequences that respond to small molecule effectors. | 2010 | BMC Mol. Biol. | pmid:20698993 |
Dai L et al. | First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces. | 2010 | Antimicrob. Agents Chemother. | pmid:20585133 |
Javsicas LH et al. | Disposition of oral telithromycin in foals and in vitro activity of the drug against macrolide-susceptible and macrolide-resistant Rhodococcus equi isolates. | 2010 | J. Vet. Pharmacol. Ther. | pmid:20646201 |
Bellissimo-Rodrigues F et al. | Bacillary angiomatosis in a pregnant woman. | 2010 | Int J Gynaecol Obstet | pmid:20650456 |
Chemli J et al. | [Kawasaki disease and Mycoplasma pneumoniae infection]. | 2010 | Med Mal Infect | pmid:20650584 |
Wang CH et al. | [Effect of interstitial cells of Cajal on gastrointestinal motility induced by motilin receptor agonist ABT-229]. | 2010 | Zhonghua Er Ke Za Zhi | pmid:20654011 |
Dando SJ et al. | Maternal administration of erythromycin fails to eradicate intrauterine ureaplasma infection in an ovine model. | 2010 | Biol. Reprod. | pmid:20610808 |
Eggo MC | Molecular regulation of thyroid gland function. | 2010 | Curr Opin Endocrinol Diabetes Obes | pmid:20616713 |
Zhang H et al. | Complete biosynthesis of erythromycin A and designed analogs using E. coli as a heterologous host. | 2010 | Chem. Biol. | pmid:21095573 |
Tunca M et al. | Topical nadifloxacin 1% cream vs. topical erythromycin 4% gel in the treatment of mild to moderate acne. | 2010 | Int. J. Dermatol. | pmid:21091683 |
van den Bruele T et al. | Campylobacter jejuni bacteremia and Helicobacter pylori in a patient with X-linked agammaglobulinemia. | 2010 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:20556465 |
Yergeau E et al. | Metatranscriptomic analysis of the response of river biofilms to pharmaceutical products, using anonymous DNA microarrays. | 2010 | Appl. Environ. Microbiol. | pmid:20562274 |
Aitken CE and Puglisi JD | Following the intersubunit conformation of the ribosome during translation in real time. | 2010 | Nat. Struct. Mol. Biol. | pmid:20562856 |
Wultańska D et al. | [Prevalence of Clostridium difficile in the gastrointestinal tract of hospitalized children under two years of age]. | 2010 | Med Dosw Mikrobiol | pmid:20564974 |
Sai Y et al. | Proton-coupled erythromycin antiport at rat blood-placenta barrier. | 2010 | Drug Metab. Dispos. | pmid:20566696 |
Hölzel CS et al. | Resistance to linezolid in a porcine Clostridium perfringens strain carrying a mutation in the rplD gene encoding the ribosomal protein L4. | 2010 | Antimicrob. Agents Chemother. | pmid:20065060 |
Keenan JD et al. | Cost analysis of povidone-iodine for ophthalmia neonatorum prophylaxis. | 2010 | Arch. Ophthalmol. | pmid:20065233 |
Lehtopolku M et al. | Antimicrobial susceptibilities of multidrug-resistant Campylobacter jejuni and C. coli strains: in vitro activities of 20 antimicrobial agents. | 2010 | Antimicrob. Agents Chemother. | pmid:20038624 |
Severin JA et al. | Nasal carriage of methicillin-resistant and methicillin-sensitive strains of Staphylococcus sciuri in the Indonesian population. | 2010 | Antimicrob. Agents Chemother. | pmid:20837756 |
Jeong JW et al. | In vitro and in vivo activities of LCB01-0371, a new oxazolidinone. | 2010 | Antimicrob. Agents Chemother. | pmid:20855730 |