erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (20)
- J. Antimicrob. Chemother. (9)
- Drug Metab. Dispos. (2)
- Others (20)
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lengyel C et al. | [Erythrocyte-induced "torsade de pointes" ventricular tachycardia]. | 1997 | Orv Hetil | pmid:9153994 |
| Ehrmann EH | Infective endocarditis and practical guides for successful dentistry. | 1997 | Aust Dent J | pmid:9153847 |
| McDonald PJ et al. | Studies on absorption of a newly developed enteric-coated erythromycin base. | 1977 | J Clin Pharmacol | pmid:915024 |
| Colburn WA et al. | Pharmacokinetics of erythromycin on repetitive dosing. | 1977 | J Clin Pharmacol | pmid:915023 |
| Watts JL and Salmon SA | Activity of selected antimicrobial agents against strains of Staphylococcus aureus isolated from bovine intramammary infections that produce beta-lactamase. | 1997 | J. Dairy Sci. | pmid:9149974 |
| Panhuyzen-Goedkoop NM and Crijns HJ | [Iatrogenic collapse; can this be prevented?]. | 1997 | Ned Tijdschr Geneeskd | pmid:9148161 |
| Barrett MS and Jones RN | Antimicrobial activity and spectrum of sparfloxacin tested against erythromycin-resistant Streptococcus pneumoniae isolates. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:9147907 |
| Kendall BJ et al. | The effect of intravenous erythromycin on solid meal gastric emptying in patients with chronic symptomatic post-vagotomy-antrectomy gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9146779 |
| Schülin T et al. | In vitro activity of RU 64004, a new ketolide antibiotic, against gram-positive bacteria. | 1997 | Antimicrob. Agents Chemother. | pmid:9145901 |
| Ross JI et al. | Clinical resistance to erythromycin and clindamycin in cutaneous propionibacteria isolated from acne patients is associated with mutations in 23S rRNA. | 1997 | Antimicrob. Agents Chemother. | pmid:9145890 |
| Ednie LM et al. | Susceptibilities of 228 penicillin- and erythromycin-susceptible and -resistant pneumococci to RU 64004, a new ketolide, compared with susceptibilities to 16 other agents. | 1997 | Antimicrob. Agents Chemother. | pmid:9145864 |
| Sturm AW et al. | Over-the-counter availability of antimicrobial agents, self-medication and patterns of resistance in Karachi, Pakistan. | 1997 | J. Antimicrob. Chemother. | pmid:9145830 |
| Wise R et al. | The activity of the methylpiperazinyl fluoroquinolone CG 5501: a comparison with other fluoroquinolones. | 1997 | J. Antimicrob. Chemother. | pmid:9145816 |
| Ng PC et al. | Erythromycin treatment for gastrointestinal dysmotility in preterm infants. | 1997 | J Paediatr Child Health | pmid:9145359 |
| Tsuruta S et al. | Effects of erythromycin, clarithromycin and rokitamycin on nifedipine metabolism in rats. | 1997 | Biol. Pharm. Bull. | pmid:9145220 |
| Cucchiara S et al. | Antroduodenal motor effects of intravenous erythromycin in children with abnormalities of gastrointestinal motility. | 1997 | J. Pediatr. Gastroenterol. Nutr. | pmid:9144124 |
| Knothe H | Medical implications of macrolide resistance and its relationship to the use of tylosin in animal feeds. | 1977 | Infection | pmid:914361 |
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| GarcÃa-Martos P et al. | Increase in high resistance to penicillin of clinical isolates of Streptococcus pneumoniae in Cádiz, Spain. | 1997 May-Jun | Chemotherapy | pmid:9142458 |
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| Furuya E | Removal of interference by erythromycin, phenazopyridine, and methenamine mandelate in the Porter-Silber reaction. | 1977 | Clin. Chem. | pmid:912880 |
| Nakagawa A et al. | A search for Pseudomonas alginate biosynthesis inhibitors from microbial metabolites. | 1997 | J. Antibiot. | pmid:9127207 |
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| Samsom M et al. | Effects of oral erythromycin on fasting and postprandial antroduodenal motility in patients with type I diabetes, measured with an ambulatory manometric technique. | 1997 | Diabetes Care | pmid:9118759 |
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| Leach AJ et al. | A prospective study of the impact of community-based azithromycin treatment of trachoma on carriage and resistance of Streptococcus pneumoniae. | 1997 | Clin. Infect. Dis. | pmid:9114185 |
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| Monji H et al. | Highly sensitive high-performance liquid chromatographic determination method for a new erythromycin derivative, EM523, and its major metabolites in human plasma and urine using post-column tris(2,2'-bipyridine) ruthenium(III) chemiluminescence detection. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9106057 |
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| Kato A | [Effect of erythromycin and clarithromycin on ion transport across dissected canine tracheal epithelium]. | 1997 | Nippon Jibiinkoka Gakkai Kaiho | pmid:9103848 |
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| Singh G et al. | An audit of the problems in management of patients with gonorrhoea. | 1997 | Int J STD AIDS | pmid:9089036 |
| Sato F et al. | EM574, an erythromycin derivative, is a motilin receptor agonist in the rabbit. | 1997 | Eur. J. Pharmacol. | pmid:9088872 |