erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, belongs to the TnGBS family of integrative and conjugative elements. | 2014 | Antimicrob. Agents Chemother. | pmid:24449773 |
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Cai HL et al. | Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. | 2014 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:24424301 |
Khannous L et al. | Isolation of a novel amylase and lipase-producing Pseudomonas luteola strain: study of amylase production conditions. | 2014 | Lipids Health Dis | pmid:24405763 |
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Wu H et al. | Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea. | 2014 | Microb. Cell Fact. | pmid:25391994 |
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Arenz S et al. | Drug sensing by the ribosome induces translational arrest via active site perturbation. | 2014 | Mol. Cell | pmid:25306253 |
Belén Flórez A et al. | Molecular identification and quantification of tetracycline and erythromycin resistance genes in Spanish and Italian retail cheeses. | 2014 | Biomed Res Int | pmid:25302306 |
Farley R et al. | Antibiotics for bronchiolitis in children under two years of age. | 2014 | Cochrane Database Syst Rev | pmid:25300167 |
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Katayama Y et al. | Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. | 2014 | Brain Res. | pmid:25264351 |
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Kemp MW et al. | Repeated maternal intramuscular or intraamniotic erythromycin incompletely resolves intrauterine Ureaplasma parvum infection in a sheep model of pregnancy. | 2014 | Am. J. Obstet. Gynecol. | pmid:24589547 |
Carls A et al. | Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. | 2014 | Br J Clin Pharmacol | pmid:25139487 |
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Compain F et al. | Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids. | 2014 | Antimicrob. Agents Chemother. | pmid:25136004 |
Hoover WD et al. | Topical antibiotic monotherapy prescribing practices in acne vulgaris. | 2014 | J Dermatolog Treat | pmid:24171409 |
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Shen Y et al. | Mitigative effect of erythromycin on PMMA challenged preosteoblastic MC3T3-E1 cells. | 2014 | ScientificWorldJournal | pmid:25110723 |
Tagawa J et al. | Development of a novel plasmid vector pTIO-1 adapted for electrotransformation of Porphyromonas gingivalis. | 2014 | J. Microbiol. Methods | pmid:25102110 |
Serna-Tamayo C et al. | Neonatal and infantile acne vulgaris: an update. | 2014 | Cutis | pmid:25101339 |
Kinouchi H et al. | Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance. | 2014 | Biol. Pharm. Bull. | pmid:25087959 |
Bos JC et al. | Antimicrobial susceptibility of Streptococcus pneumoniae in adult patients with pneumococcal pneumonia in an urban hospital in Mozambique. | 2014 | BMC Res Notes | pmid:24568650 |
Feng Y et al. | Prevalence, distribution, and diversity of Escherichia coli, Staphylococcus aureus, and Salmonella in kiwifruit orchards and processing plants. | 2014 | Foodborne Pathog. Dis. | pmid:25054781 |
Sahu AK et al. | Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. | 2014 | Biomed Res Int | pmid:25045692 |
Piccinelli G et al. | In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae. | 2014 | Antimicrob. Agents Chemother. | pmid:24379197 |
Ramos FL and Criner GJ | Use of long-term macrolide therapy in chronic obstructive pulmonary disease. | 2014 | Curr Opin Pulm Med | pmid:24378875 |
Johansson M et al. | Sequence-dependent elongation dynamics on macrolide-bound ribosomes. | 2014 | Cell Rep | pmid:24836000 |
Jing YR et al. | The synthesis of novel taxoids for oral administration. | 2014 | Bioorg. Med. Chem. | pmid:24332858 |
Borbón-Esquer EM et al. | SCCmec types and pvl gene in methicillin-resistant Staphylococcus aureus strains from children hospitalized in a tertiary care hospital in Mexico. | 2014 | Scand. J. Infect. Dis. | pmid:24832853 |
Wang Z et al. | High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. | 2014 | Clin. Microbiol. Infect. | pmid:24816168 |
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Murphree CA et al. | Antibiotic resistance among cultured bacterial isolates from bioethanol fermentation facilities across the United States. | 2014 | Curr. Microbiol. | pmid:24748439 |
Sakamoto N et al. | Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. | 2014 | Intern. Med. | pmid:24739609 |
Dechert-Schmitt AM et al. | Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. | 2014 | Nat Prod Rep | pmid:24514754 |
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Boomkamp SD et al. | Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model. | 2014 | Br. J. Pharmacol. | pmid:24467222 |
Jun BY et al. | Premedication with erythromycin improves endoscopic visualization of the gastric mucosa in patients with subtotal gastrectomy: a prospective, randomized, controlled trial. | 2014 | Surg Endosc | pmid:24380989 |
Ren WP et al. | Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. | 2014 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:24347324 |
Brenciani A et al. | Genetic determinants and elements associated with antibiotic resistance in viridans group streptococci. | 2014 | J. Antimicrob. Chemother. | pmid:24343896 |
Lu WC et al. | Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. | 2014 | Neurol. Sci. | pmid:24277204 |
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Dalbøge CS et al. | Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. | 2014 | J. Cyst. Fibros. | pmid:24035278 |
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Wang Z et al. | MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. | 2015 | PLoS ONE | pmid:25706647 |
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Lysnyansky I et al. | Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. | 2015 | Microb. Drug Resist. | pmid:25734368 |
Abreu AC et al. | Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. | 2015 | Microb. Drug Resist. | pmid:25734256 |
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Nagelreiter C et al. | Dilution of semi-solid creams: influence of various production parameters on rheological properties and skin penetration. | 2015 | Int J Pharm | pmid:25475015 |
Harmer CJ et al. | A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. | 2015 | J. Antimicrob. Chemother. | pmid:25468903 |
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Ayazi P et al. | Tick-borne Relapsing Fever in Children in the North-west of Iran, Qazvin. | 2015 | Prague Med Rep | pmid:26445390 |
Banik A et al. | Inducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital. | 2015 | J Infect Dev Ctries | pmid:26230122 |
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