erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Huang M et al. Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. 2015 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:26223917
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Takagi M et al. Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. 2015 Drug Metab. Pharmacokinet. pmid:26195223
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Dayie NT et al. Multidrug-Resistant Streptococcus pneumoniae Isolates from Healthy Ghanaian Preschool Children. 2015 Microb. Drug Resist. pmid:26172078
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Gagliotti C et al. A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. 2015 Acta Paediatr. pmid:26058421
Dermota U et al. Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. 2015 Int. J. Med. Microbiol. pmid:26055648
Drouet M et al. Endothelial Cell Toxicity of Vancomycin Infusion Combined with Other Antibiotics. 2015 Antimicrob. Agents Chemother. pmid:26055373
Reeves M et al. Acute colonic pseudo-obstruction in pregnancy. 2015 ANZ J Surg pmid:26044983
Vlakh EG et al. Preparation and characterization of macroporous monoliths imprinted with erythromycin. 2015 J Sep Sci pmid:26033867
Wang L et al. Changes in diversity of cultured bacteria resistant to erythromycin and tetracycline in swine manure during simulated composting and lagoon storage. 2015 Lett. Appl. Microbiol. pmid:26031793
Wang Z et al. MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. 2015 PLoS ONE pmid:25706647
Yoon IA et al. Clinical significance of serotype V among infants with invasive group B streptococcal infections in South Korea. 2015 Int. J. Infect. Dis. pmid:26026823
Gherardi G et al. Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy. 2015 Eur. J. Clin. Microbiol. Infect. Dis. pmid:26024763
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Pesola AK et al. Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. 2015 Euro Surveill. pmid:25990232
Sun XJ et al. Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. 2015 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:25957293
Guo MT et al. Insights into the amplification of bacterial resistance to erythromycin in activated sludge. 2015 Chemosphere pmid:25957255
Kasai A et al. Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011. 2015 J. Med. Microbiol. pmid:25934551
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Romaniszyn D et al. Epidemiology, antibiotic consumption and molecular characterisation of Staphylococcus aureus infections--data from the Polish Neonatology Surveillance Network, 2009-2012. 2015 BMC Infect. Dis. pmid:25888217
Park JY et al. Construction of a shuttle vector based on the small cryptic plasmid pJY33 from Weissella cibaria 33. 2015 Plasmid pmid:25882072
Jakubů V et al. Minimum inhibitory concentrations of erythromycin and other antibiotics for Czech strains of Bordetella pertussis. 2015 Epidemiol Mikrobiol Imunol pmid:25872990
Koutsogiannidis CP et al. Decreased DNA Disruption in the Porcine Neocortex with Erythromycin Preconditioning during Prolonged Hypothermic Circulatory Arrest: Evidence for Neuroprotection. 2015 J Card Surg pmid:25858150
Tojima I et al. Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. 2015 Auris Nasus Larynx pmid:25769240
Hao H et al. Identification of Campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex TaqMan MGB real-time PCR. 2015 J. Appl. Microbiol. pmid:25766481
Nonaka L et al. Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. 2015 Lett. Appl. Microbiol. pmid:25765542
Mills RO et al. Epidemiology of pneumococcal carriage in children under five years of age in Accra, Ghana. 2015 Infect Dis (Lond) pmid:25761718
Hersch M et al. Prokinetic drugs for gastric emptying in critically ill ventilated patients: Analysis through breath testing. 2015 J Crit Care pmid:25746849
Lee S et al. Functional analysis of Vibrio vulnificus RND efflux pumps homologous to Vibrio cholerae VexAB and VexCD, and to Escherichia coli AcrAB. 2015 J. Microbiol. pmid:25740377
Lysnyansky I et al. Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. 2015 Microb. Drug Resist. pmid:25734368
Abreu AC et al. Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. 2015 Microb. Drug Resist. pmid:25734256
Ou H et al. Selective removal of erythromycin by magnetic imprinted polymers synthesized from chitosan-stabilized Pickering emulsion. 2015 J. Hazard. Mater. pmid:25704432
Ikebe T et al. Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. 2015 Epidemiol. Infect. pmid:25703404
Li Y et al. Where macrolide resistance is prevalent. 2015 APMIS pmid:25703275
Chemler JA et al. Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination. 2015 J. Am. Chem. Soc. pmid:26230368
Choi JH et al. Distribution of emm types among group A Streptococcus isolates from children in Korea. 2015 Diagn. Microbiol. Infect. Dis. pmid:25700867
Luo H et al. Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. 2015 Avian Pathol. pmid:25690020
Sessa R et al. Effects of Mentha suaveolens essential oil on Chlamydia trachomatis. 2015 Biomed Res Int pmid:25685793
Shi JG et al. Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib. 2015 Clin. Pharmacol. Ther. pmid:25670523
Xu CW et al. First report of macrolide resistance gene erm(T) harbored by a novel small plasmid from Erysipelothrix rhusiopathiae. 2015 Antimicrob. Agents Chemother. pmid:25666150
Naquin A et al. Presence of antibiotic resistance genes in a sewage treatment plant in Thibodaux, Louisiana, USA. 2015 Bioresour. Technol. pmid:25662190
García-Mayor MA et al. Occurrence of erythromycin residues in sheep milk. Validation of an analytical method. 2015 Food Chem. Toxicol. pmid:25637760
Chan BC et al. Combating against methicillin-resistant Staphylococcus aureus - two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. 2015 J. Pharm. Pharmacol. pmid:25212982
Wu H et al. Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. 2015 Appl. Microbiol. Biotechnol. pmid:25549616
Cetecioglu Z et al. Acute effect of erythromycin on metabolic transformations of volatile fatty acid mixture under anaerobic conditions. 2015 Chemosphere pmid:25542637
Novak I and Kovač B Electronic structure of antibiotic erythromycin. 2015 Spectrochim Acta A Mol Biomol Spectrosc pmid:25528514
Ansari NN et al. A randomized clinical trial comparing pulsed ultrasound and erythromycin phonophoresis in the treatment of patients with chronic rhinosinusitis. 2015 Physiother Theory Pract pmid:25495769
Nagelreiter C et al. Dilution of semi-solid creams: influence of various production parameters on rheological properties and skin penetration. 2015 Int J Pharm pmid:25475015
Harmer CJ et al. A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. 2015 J. Antimicrob. Chemother. pmid:25468903
Wan J et al. Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. 2015 J. Hazard. Mater. pmid:25464321
Zhou Z et al. Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. 2015 Antimicrob. Agents Chemother. pmid:25451048
Hur J et al. Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. 2015 Chem. Res. Toxicol. pmid:25811541
Haxel BR et al. Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis. 2015 Laryngoscope pmid:25425539
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Galvidis I et al. Group determination of 14-membered macrolide antibiotics and azithromycin using antibodies against common epitopes. 2015 Anal. Biochem. pmid:25256165
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Kempe H et al. Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. 2015 Pharm. Res. pmid:25103333
Chen Y et al. The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m(3) fermenter. 2015 Bioprocess Biosyst Eng pmid:25042891
Llorca M et al. Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. 2015 Chemosphere pmid:24972175
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Ayazi P et al. Tick-borne Relapsing Fever in Children in the North-west of Iran, Qazvin. 2015 Prague Med Rep pmid:26445390
Yamaguchi M et al. Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche. 2015 Cell Rep pmid:26440893
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Borges V et al. Helicobacter pullorum isolated from fresh chicken meat: antibiotic resistance and genomic traits of an emerging foodborne pathogen. 2015 Appl. Environ. Microbiol. pmid:26386065
Dixit S and Park JH Enantioseparation of basic chiral drugs on a carbamoylated erythromycin-zirconia hybrid monolith using capillary electrochromatography. 2015 J Chromatogr A pmid:26372443
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Aydın S et al. The joint acute effect of tetracycline, erythromycin and sulfamethoxazole on acetoclastic methanogens. 2015 Water Sci. Technol. pmid:25909721
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