erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Igari J and Kano M | [Basic study on chemotherapy of urinary tract infection. 3. Effect of urine pH on antibacterial activity of macrolides, lincomycin and clinimycin on Escherichia coli]. | 1968 | Jpn J Antibiot | pmid:4887887 |
Lange A and Volkening R | [Resistance quota of some bacterial species to various antibiotics]. | 1968 | Med Welt | pmid:4888218 |
Savel'eva TL | [Antibiotics in the treatment of actinomycoses]. | 1968 | Antibiotiki | pmid:4878102 |
RychlÃk I and Cerná J | Cross resistance of Escherichia coli B. ribosomes to inhibition of the puromycin reaction by erythromycin, spiramycin and chloramphenicol. | 1968 | Hoppe-Seyler's Z. Physiol. Chem. | pmid:4878426 |
Kiselev RN | [Intestinal microflora in mice and its change under the effect of antibiotics]. | 1968 | Antibiotiki | pmid:4879870 |
Garanin BA | [Sensitivity toward antibiotics of Shigella, isolated rom the patients in years 1960-1965, from the data from Hospital of Infectious Diseases]. | 1968 | Antibiotiki | pmid:4880237 |
Gomez JR and Gomez G | Comparative trial of erythromycin and tetracycline in common infections found in general practice. | 1968 | Br J Clin Pract | pmid:4880249 |
Kaempfer R | Ribosomal subunit exchange during protein synthesis. | 1968 | Proc. Natl. Acad. Sci. U.S.A. | pmid:4880603 |
Nuzzolo L et al. | [Research on the antibacterial activity in vitro, and on blood concentrations in man, of an association of erythromycin with sulfadiazine, sulfamerazine and sulfamethazine]. | 1968 | Clin Ter | pmid:4883849 |
Avian tuberculosis. | 1968 | Scott Med J | pmid:4884700 | |
Anaka K and Teraoka H | Effect of erythromycin on polylysine synthesis directed by polyadenylic acid in an Escherichia coli cell-free system. | 1968 | J. Biochem. | pmid:4885037 |
Bouanchaud DH et al. | Elimination by ethidium bromide of antibiotic resistance in enterobacteria and staphylococci. | 1968 | J. Gen. Microbiol. | pmid:4885039 |
Tanaka K et al. | Erythromycin-resistant mutant of Escherichia coli with altered ribosomal protein component. | 1968 | Science | pmid:4886608 |
Linnane AW et al. | The biogenesis of mitochondria. V. Cytoplasmic inheritance of erythromycin resistance in Saccharomyces cerevisiae. | 1968 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5238670 |
Linnane AW et al. | The biogenesis of mitochondria, VI. Biochemical basis of the resistance of Saccharomyces cerevisiae toward antibiotics which specifically inhibit mitochondrial protein synthesis. | 1968 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5240029 |
Woods R | Antibiotic treatment of pyogenic infections of dental origin. | 1968 | Aust Dent J | pmid:5240656 |
Berthelot et al. | [Clinical study and determination of blood and salivary level of erythromycin ethyl-succinate]. | 1968 | Inf Dent | pmid:5245648 |
Cooper RG et al. | An erythromycin-resistant pneumococcus. | 1968 | Med. J. Aust. | pmid:4385911 |
Lang N et al. | On the mechanism of hormone action. VII. Induction by cortisol of a messenger RNA coding for tyrosine-alpha-ketoglutarate transaminase for an in vitro system. | 1968 | Acta Endocrinol. | pmid:4384442 |
Corse J and Williams RE | Antibiotic resistance of coagulase-negative staphylococci and micrococci. | 1968 | J. Clin. Pathol. | pmid:5191722 |
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Schonell ME et al. | Disseminated infection with Mycobacterium avium: I. Clinical features, treatment and pathology. | 1968 | Tubercle | pmid:4969143 |
Clark J et al. | Disseminated infection with Mycobacterium avium: II. Bacteriology and drug susceptibility. | 1968 | Tubercle | pmid:4969144 |
Saggers BA and Lawson D | In vivo penetration of antibiotics into sputum in cystic fibrosis. | 1968 | Arch. Dis. Child. | pmid:4969417 |
Franco S et al. | Erythromycin in childhood pneumonias. | 1968 | Curr Ther Res Clin Exp | pmid:4969674 |
Edmond E et al. | Avian tuberculosis. | 1968 | Scott Med J | pmid:5751239 |
Pulverer G | [Studies with lysotaphin. II. Lysostaphin sensitivity of 230 strains of Staph. aureus of animal origin]. | 1968 | Z Med Mikrobiol Immunol | pmid:5751715 |
Mikuni M et al. | [Present status of chemotherapy in ophthalmology, with special reference to recent antibiotics]. | 1968 | Ganka | pmid:5752591 |
Willcox RR | Erythromycin in the treatment of non-gonococcal urethritis. | 1968 | Br J Vener Dis | pmid:5761021 |
Schultz EJ | Evaluation of erythromycin in the treatment of infectious bovine mastitis. | 1968 | J. Am. Vet. Med. Assoc. | pmid:5761379 |
Gabraschanski P | [Gallimycin for therapy and prophylaxis of some diseases or the rock partridge in Bulgaria]. | 1968 | Dtsch Tierarztl Wochenschr | pmid:5693286 |
Monnier J and Bourse R | [Antibacterial activity in vitro of a new rifamycin: rifamide]. | 1968 | Pathol Biol | pmid:4972879 |
Poralla K and Zähner H | [Metabolic products of microorganisms. 62. The inhibition of the incorporation of threonine in sRNA in cell-free systems and of the synthesis of proteins and nucleic acids in the cell by the antibiotic borrelidin]. | 1968 | Arch Mikrobiol | pmid:4974079 |
Ozawa A | [On the sensitivity of various gram-negative bacilli to demethylchlortetracycline (Ledermycin)]. | 1968 | Jpn J Antibiot | pmid:4974355 |
Malski M | [Effect of penicillin, aureomycin, chloramphenicol and erythromycin on tubercle bacilli]. | 1968 | Gruzlica | pmid:4974660 |
Benzi G et al. | [Effect of erythromycin, various tetracyclines and rifomycin SV, on extrahepatic bile ducts]. | 1968 | Boll Chim Farm | pmid:4976427 |
Wakuta T | Mutual relationship of Candida and Lactobacillus in mixed culture. | 1968 | Bull. Tokyo Med. Dent. Univ. | pmid:4976549 |
Vakulenko NA | [Unification of the method for determination of biological activity of antibiotics by means of single test culture]. | 1968 | Antibiotiki | pmid:4976625 |
Rotheim MB and Ravin AW | Inactivation and reversion of multisite streptomycin resistance mutations of Pneumococcus. | 1968 | Mol. Gen. Genet. | pmid:5713396 |
Onodera T et al. | Effect of fluid and antibiotic administration on experimental fecal peritonitis. | 1968 | Tohoku J. Exp. Med. | pmid:5715596 |
Smith LT et al. | Reproductive performance of pheasant breeder hens. | 1968 | Poult. Sci. | pmid:5716660 |
Velluti G and Grifa P | [In vitro activity of erythromycin on various mycobacterium strains]. | 1968 | G Mal Infett Parassit | pmid:4976935 |
Levy A et al. | [Study "in vitro" and "in vivo" using erythromycin stearate in the therapy of respiratory and cutaneous infections]. | 1968 | Rev Bras Med | pmid:5717048 |
Acocella G et al. | Biliary excretion of antibiotics in man. | 1968 | Gut | pmid:5717103 |
Voors AW and Stewart GT | Statistical analysis of staphylococcal infection in hospital patients in relation to use of antibiotics and other factors. | 1968 | J Hyg (Lond) | pmid:5250128 |
Kanno M et al. | [Study on progressive muscular dystrophy. 1. Influence of the various drugs on serum enzyme activity and the degree of disability]. | 1968 | Iryo | pmid:5717702 |
Schlecht S and Westphal O | [Antibiotic sensitivity in S- and R-forms of Salmonella minnesota]. | 1968 | Naturwissenschaften | pmid:5725584 |
Akzhigitov GH et al. | [The treatment of traumatic pancreatitis with antibiotics and their secretion with pancreatic juice]. | 1968 | Vestn. Khir. Im. I. I. Grek. | pmid:5729234 |
Sugiyama H | [Experimental studies on control of dental caries. 2. Erythromycin and oral microbial flora]. | 1968 | Aichi Gakuin Daigaku Shigakkai Shi | pmid:5261349 |
Mozziconacci P and Attal C | [Treatment of rheumatic cardiopathies]. | 1968 | Sem Hop | pmid:4307324 |
Cairella M and Marasà G | [The chemoantibiotics in infections of the bile ducts]. | 1968 | Clin Ter | pmid:4982819 |
da Silva WB et al. | [Use of a chloramphenicol-erythromycin combination in the treatment of lung diseases in children]. | 1968 | Hospital (Rio J) | pmid:5308493 |
Puito L | [Antibiotic therapy in infancy]. | 1968 | Pediatria (Napoli) | pmid:4312284 |
Jones PH and Rowley EK | Chemical modifications of erythromycin antibiotics. I. 3'-de(dimethylamino)erythromycin A and B. | 1968 | J. Org. Chem. | pmid:5636610 |
Thomas DY and Wilkie D | Recombination of mitochondrial drug-resistance factors in Saccharomyces cerevisiae. | 1968 | Biochem. Biophys. Res. Commun. | pmid:5637042 |
Petit JF et al. | Biosynthesis of the peptidoglycan of bacterial cell walls. VII. Incorporation of serine and glycine into interpeptide bridges in Staphylococcus epidermidis. | 1968 | J. Biol. Chem. | pmid:5638592 |
Hanley JE et al. | An evaluation and comparison of spectinomycin and spectinomycin-erythromycin combinations for infectious coryza. | 1968 | Avian Dis. | pmid:5643698 |
Breitfellner G et al. | [Staphylococci in the Vienna area. Epidemiology, antibiotic sensitivity and therapeutic aspects]. | 1968 | Wien. Klin. Wochenschr. | pmid:5188335 |
Sotaniemi E and Huhti E | Bronchial asthma and toxic hepatitis. | 1968 | Ann Allergy | pmid:5644356 |
Parisi JT and Suling WJ | Antibiotic resistance of glycine-resistant variants of Staphylococcus aureus. | 1968 | Can. J. Microbiol. | pmid:5188340 |
Desmyter J | Lincomycin resistance of erythromycin-resistant cocci. | 1968 | N. Engl. J. Med. | pmid:5644571 |
Bulger RJ and Sherris JC | Decreased incidence of antibiotic resistance among Staphylococcus aureus. A study in a university hospital over a 9-year period. | 1968 | Ann. Intern. Med. | pmid:5188901 |
Popovici GG et al. | The influence of some antibiotics on glucose-6-P-NADP-oxido-reductase (G6PDH) activity. | 1968 | Arch Int Pharmacodyn Ther | pmid:5646007 |
Sprunt K et al. | Penicillin resistant alpha Streptococci in pharynx of patients given oral penicillin. | 1968 | Pediatrics | pmid:5188913 |
Novick RP and Roth C | Plasmid-linked resistance to inorganic salts in Staphylococcus aureus. | 1968 | J. Bacteriol. | pmid:5646621 |
Alberti RL | Teeth discoloration and enamel hypoplasia caused by erythromycin. | 1968 | S. Afr. Med. J. | pmid:5647172 |
Doyle WM et al. | Pulmonary disease caused by Mycobacterium xenopei. | 1968 | Am. Rev. Respir. Dis. | pmid:5647216 |
Thomas DY and Wilkie D | Inhibition of mitochondrial synthesis in yeast by erythromycin: cytoplasmic and nuclear factors controlling resistance. | 1968 | Genet. Res. | pmid:5648765 |
Osman HG et al. | Factors influencing the biosynthesis of erythromycin by Streptomyces erythreus. | 1968 | Z. Allg. Mikrobiol. | pmid:4916831 |
Simon C and Latz E | [Antibiotic therapy of staphylococcal infections. The influence of chloramphenicol and erythromycin on the bactericidal effect of penicillin G and methicillin in vitro]. | 1968 | Med Welt | pmid:5663162 |
Narasimhan MJ and Ganla VG | The broad-spectrum and the macrolide antibiotics and the ciliary barrier. | 1968 | Hindustan Antibiot Bull | pmid:5663533 |
Bertrand JL | [Combination of propionyl-erythromycin, tetracycline and lysozyme in anti-infective therapy in adults and children]. | 1968 | Lyon Med | pmid:5664960 |
Bülow P | A new epidemic phage type of Staphylococcus aureus. 3. Occurrence and spread of "type 6557", with special reference to the consumption of some antibiotics. | 1968 | Acta Pathol Microbiol Scand | pmid:4244485 |
Lamb AJ et al. | The biogenesis of mitochondria. 4. The differentiation of mitochondrial and cytoplasmic protein synthesizing systems in vitro by antibiotics. | 1968 | Biochim. Biophys. Acta | pmid:5667290 |
Macfarlane JA et al. | Spiramycin the the prevention of postoperative staphylococcal infection. | 1968 | Lancet | pmid:4169066 |
Pacha RE | Characteristics of Cytophaga psychrophila (Borg) isolated during outbreaks of bacterial cold-water disease. | 1968 | Appl Microbiol | pmid:4169926 |
Chisholm WS | Erythromycin-sulfas in pediatric practice: efficacy and patient acceptance. | 1968 | Ariz Med | pmid:5674274 |
Johnstone FR and Cockcroft WH | Clostridium welchii resistance to tetracycline. | 1968 | Lancet | pmid:4170649 |
Higashide E et al. | Enduracidin, a new antibiotic. I. Streptomyces fungicidicus No. B5477, an enduracidin producing organism. | 1968 | J. Antibiot. | pmid:5674368 |
Hadida E et al. | [Dissecting cellulitis of the scalp]. | 1968 | Bull Soc Fr Dermatol Syphiligr | pmid:5677894 |
Chernomordik AB | [Antibiotic lincomycin]. | 1968 | Antibiotiki | pmid:4894135 |
VaÄsberg GE and Meshkov MI | [Treatment of patients with microbial eczema by prodigiozan in combination with antibiotics]. | 1968 | Antibiotiki | pmid:5678111 |
Gause GG and Grünberger D | Translational characteristics of ribosomes and coding properties of transfer RNA in the mutant of bacterium paracoli with the increased GC content of DNA. | 1968 | Biochim. Biophys. Acta | pmid:5680608 |
Arret B and Eckert J | New developments in antibiotic interference thresholds of microbial assays. | 1968 | J Pharm Sci | pmid:4297949 |
Wayland LG and Weiss PJ | Identification of antibiotics in sensitivity disks. | 1968 | J Pharm Sci | pmid:4173079 |
Swart H | [A case of Gaffkya sepsis]. | 1968 | Ned Tijdschr Geneeskd | pmid:5680825 |
Rouquès L | [Scarlet fever in 1968]. | 1968 | Presse Med | pmid:5305215 |
Winningham DG et al. | Diffusion of antibiotics from plasma into prostatic fluid. | 1968 | Nature | pmid:4298194 |
Peterson JM and Guild WR | Fractionated strands of bacterial deoxyribonucleic acid. 3. Transformation efficiencies and rates of phenotypic expression. | 1968 | J. Bacteriol. | pmid:4387147 |
Grady JE | Recent developments in lincomycin research. | 1968 | Int Z Klin Pharmakol Ther Toxikol | pmid:4388454 |
Tereshin IM and Belousova II | [Effect of some antibiotics on the transfer of the resistance to tetracycline and chloramphenicol by means of the episome factor (Rtf)]. | 1968 | Antibiotiki | pmid:4298603 |
Rodovalho SF | [Tolerance and efficiency of erythromycin suppositories used in respiratory infections in ambulatory pediatric practice]. | 1968 | Hospital (Rio J) | pmid:5306207 |
Nakazawa S et al. | [Experimental chemotherapy of Proteus vulgaris infection]. | 1968 | Jpn J Antibiot | pmid:4299624 |
Hirasawa K | [Studies on renin-angiotensin system. I. Angiotensinase activities in hepatic disorders]. | 1968 | Jpn. Circ. J. | pmid:4299837 |
Alterio DL | [Clinico-parasitological evaluation of an anti-ameba therapeutic activity of a new non-absorbable erythromycin stearate preparation]. | 1968 | Hospital (Rio J) | pmid:5307504 |
Ganança MM | [Use of erythromycin suppositories in the treatment of otorhinolaryngologic infections in children]. | 1968 | Hospital (Rio J) | pmid:5307873 |
Barnes RW et al. | Studies of sterility of calf venous blood. | 1968 | Surgery | pmid:4300855 |
Ruczaj Z | Sensitivity of microorganisms to antibiotics produced by them. | 1968 | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:4302938 |
Siegenthaler W et al. | [New antibiotics, with the exception of penicillins, streptomycin, tetracyclines and chloramphenicol]. | 1968 | Antibiot Chemother | pmid:4302993 |
Minkova GL | [On the sensitivity of microflora of burn wounds to antibiotics]. | 1968 | Antibiotiki | pmid:4305269 |