erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Alexander RE and Grogan DM Long-acting erythromycins: assessing their role in treating outpatient odontogenic infections. 2009 Tex Dent J pmid:19472551
Majumdar S et al. Vitreal kinetics of quinidine in rabbits in the presence of topically coadministered P-glycoprotein substrates/modulators. 2009 Drug Metab. Dispos. pmid:19406953
Zonenschain D et al. Erythromycin- and tetracycline-resistant lactobacilli in Italian fermented dry sausages. 2009 J. Appl. Microbiol. pmid:19426258
Bostan K et al. Prevalence and antibiotic susceptibility of thermophilic Campylobacter species on beef, mutton, and chicken carcasses in Istanbul, Turkey. 2009 Microb. Drug Resist. pmid:19432522
Crider KS et al. Antibacterial medication use during pregnancy and risk of birth defects: National Birth Defects Prevention Study. 2009 Arch Pediatr Adolesc Med pmid:19884587
Markel DC et al. Inhibitory effects of erythromycin on wear debris-induced VEGF/Flt-1 gene production and osteolysis. 2009 Inflamm. Res. pmid:19262986
Zheng J et al. Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin. 2009 J. Mol. Biol. pmid:19265703
Zou X et al. Oxygen uptake rate optimization with nitrogen regulation for erythromycin production and scale-up from 50 L to 372 m3 scale. 2009 Bioresour. Technol. pmid:18929481
Chan JC et al. Epidemiological analysis of Streptococcus pyogenes infections in Hong Kong. 2009 Pathology pmid:20001348
Hariharan H et al. Antimicrobial drug resistance as determined by the E-test in Campylobacter jejuni, C. coli, and C. lari isolates from the ceca of broiler and layer chickens in Grenada. 2009 Comp. Immunol. Microbiol. Infect. Dis. pmid:18329712
Sader HS et al. Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. 2009 Antimicrob. Agents Chemother. pmid:19289528
Razzaq A et al. Erythromycin establishes early oral feeding in neonates operated for congenital intestinal atresias. 2009 Pediatr. Surg. Int. pmid:19290531
Lindqvist M et al. A clonal outbreak of methicillin-susceptible Staphylococcus aureus with concomitant resistance to erythromycin, clindamycin and tobramycin in a Swedish county. 2009 Scand. J. Infect. Dis. pmid:19294581
Sambo N et al. Effect of the aqueous extract of Psidium guajava on erythromycin-induced liver damage in rats. 2009 Niger J Physiol Sci pmid:20234760
Kumar S et al. Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. 2009 Drug Metab. Dispos. pmid:19299527
Graham JS et al. A multi-centre dose-escalation and pharmacokinetic study of diflomotecan in patients with advanced malignancy. 2009 Cancer Chemother. Pharmacol. pmid:18654747
May T et al. Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. 2009 Antimicrob. Agents Chemother. pmid:19721076
Ghosh P et al. Modeling a macrocyclic bis[spirodiepoxide] strategy to erythronolide A. 2009 Org. Lett. pmid:19725523
Marcellini L et al. Esculentin-1b(1-18)--a membrane-active antimicrobial peptide that synergizes with antibiotics and modifies the expression level of a limited number of proteins in Escherichia coli. 2009 FEBS J. pmid:19725877
Nam HM et al. Antimicrobial resistance of streptococci isolated from mastitic bovine milk samples in Korea. 2009 J. Vet. Diagn. Invest. pmid:19737768
Cui L et al. Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus. 2009 Antimicrob. Agents Chemother. pmid:19124662
Biedenbach DJ et al. Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates. 2009 Antimicrob. Agents Chemother. pmid:19124664
Morgenstern K et al. In vitro susceptibility of Borrelia spielmanii to antimicrobial agents commonly used for treatment of Lyme disease. 2009 Antimicrob. Agents Chemother. pmid:19075048
Jakeman DL et al. Antimicrobial activities of jadomycin B and structurally related analogues. 2009 Antimicrob. Agents Chemother. pmid:19075054
House B et al. Acid-stress-induced changes in enterohaemorrhagic Escherichia coli O157 : H7 virulence. 2009 Microbiology (Reading, Engl.) pmid:19497950
Wu L et al. In vitro effects of erythromycin on RANKL and nuclear factor-kappa B by human TNF-alpha stimulated Jurkat cells. 2009 Int. Immunopharmacol. pmid:19500694
Takagi Y et al. Erythromycin-induced CXCR4 expression on microvascular endothelial cells. 2009 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:19502290
Ozaki K et al. Effects of mitemcinal (GM-611), an orally active erythromycin-derived prokinetic agent, on delayed gastric emptying and postprandial glucose in a new minipig model of diabetes. 2008 Sep-Oct J. Diabetes Complicat. pmid:18413164
Rassi H and Ghasemi SF Production of novel chemotherapeutic drugs by Streptomycetes. 2008 Oct-Dec Lik. Sprava pmid:19663015
Pomero G et al. [Neonatal group B Streptococcus infection: an integrated approach (of clinical pathologists, gynecologists, midwives, pediatricians-neonatologists) of the functional area of Cuneo (Italy)]. 2008 Nov-Dec Pediatr Med Chir pmid:19431950
Vlieghe ER et al. Trends of norfloxacin and erythromycin resistance of Campylobacter jejuni/Campylobacter coli isolates recovered from international travelers, 1994 to 2006. 2008 Nov-Dec J Travel Med pmid:19090796
Van Der Beek MT et al. Mycobacterium chelonae keratitis in a patient with Sjögren's syndrome. 2008 Mar-Apr Eur J Ophthalmol pmid:18320526
Angel MR et al. Prevalence of inducible clindamycin resistance in gram positive organisms in a tertiary care centre. 2008 Jul-Sep Indian J Med Microbiol pmid:18695329
Farrant P et al. Is erythromycin an effective treatment for chronic bullous disease of childhood? A national survey of members of the British Society for Paediatric Dermatology. 2008 Jul-Aug Pediatr Dermatol pmid:18789096
MacLaren R et al. Erythromycin vs metoclopramide for facilitating gastric emptying and tolerance to intragastric nutrition in critically ill patients. 2008 Jul-Aug JPEN J Parenter Enteral Nutr pmid:18596312
Bitarães EL et al. Compliance with antibiotic prophylaxis in children with sickle cell anemia: a prospective study. 2008 Jul-Aug J Pediatr (Rio J) pmid:18688558
Landzinski J et al. Gastric motility function in critically ill patients tolerant vs intolerant to gastric nutrition. 2008 Jan-Feb JPEN J Parenter Enteral Nutr pmid:18165446
Nouri M et al. Effect of erythromycin and gentamicin on abomasal emptying rate in suckling calves. 2008 Jan-Feb J. Vet. Intern. Med. pmid:18289310
Winters M et al. Epidemiology of invasive pneumococcal disease in BC during the introduction of conjugated pneumococcal vaccine. 2008 Jan-Feb Can J Public Health pmid:18435393
Ilisz I et al. Enantioseparation of beta-methyl-substituted amino acids with cyclodextrins by capillary zone electrophoresis. 2008 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:18514044
Verma P et al. A curious eruption: erythema gyratum repens in resolving pustular psoriasis. 2008 J Eur Acad Dermatol Venereol pmid:18005020
Montagnani F et al. Pneumococcal disease in a paediatric population in a hospital of central Italy: a clinical and microbiological case series from 1992 to 2006. 2008 J. Infect. pmid:18222005
Chen Y et al. Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea fermentation. 2008 Appl. Environ. Microbiol. pmid:18223111
Buiter HJ et al. Erythromycin precipitation in vena femoralis: investigation of crystals found in postmortem material of an intensive care unit patient. 2008 Ther Drug Monit pmid:18223476
Ressner RA et al. Activity of the Diaminopyrimidine AR-709 against recently collected multidrug-resistant isolates of invasive Streptococcus pneumoniae from North America. 2008 Antimicrob. Agents Chemother. pmid:18180346
Sader HS et al. Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. 2008 Antimicrob. Agents Chemother. pmid:18180353
Isoherranen N et al. The influence of CYP3A5 expression on the extent of hepatic CYP3A inhibition is substrate-dependent: an in vitro-in vivo evaluation. 2008 Drug Metab. Dispos. pmid:17954524
Starner TD et al. Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. 2008 Antimicrob. Agents Chemother. pmid:17954687
Morozumi M et al. Increased macrolide resistance of Mycoplasma pneumoniae in pediatric patients with community-acquired pneumonia. 2008 Antimicrob. Agents Chemother. pmid:17954691
Dias R and Caniça M Trends in resistance to penicillin and erythromycin of invasive pneumococci in Portugal. 2008 Epidemiol. Infect. pmid:17697443
Pedersen M and Hammer K The role of MOR and the CI operator sites on the genetic switch of the temperate bacteriophage TP901-1. 2008 J. Mol. Biol. pmid:18930065
Parrella E and Longo VD The chronological life span of Saccharomyces cerevisiae to study mitochondrial dysfunction and disease. 2008 Methods pmid:18930829
Dogan B et al. Antistreptococcal treatment of guttate psoriasis: a controlled study. 2008 Int. J. Dermatol. pmid:18937661
Gai Y et al. Synthesis of 3,6-bicyclolides: a novel class of macrolide antibiotics. 2008 Bioorg. Med. Chem. Lett. pmid:18996692
Kenyon S et al. Childhood outcomes after prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7-year follow-up of the ORACLE I trial. 2008 Lancet pmid:18804274
Russell AR and Steer PJ Antibiotics in preterm labour--the ORACLE speaks. 2008 Lancet pmid:18804275
Ramstedt KL et al. Changes in gallbladder volume in healthy dogs after food was withheld for 12 hours followed by ingestion of a meal or a meal containing erythromycin. 2008 Am. J. Vet. Res. pmid:18447796
Prasher P et al. Bilateral chronic peripheral ulcerative keratitis secondary to cat-scratch disease. 2008 Eye Contact Lens pmid:18463489
Fenoll A et al. In vitro activity of oral cephalosporins against pediatric isolates of Streptococcus pneumoniae non-susceptible to penicillin, amoxicillin or erythromycin. 2008 J Chemother pmid:18467242
Lambertsen L et al. Erythromycin resistance caused by erm(A) subclass erm(TR) in a Danish invasive pneumococcal isolate: are erm(A) pneumococcal isolates overlooked? 2008 Scand. J. Infect. Dis. pmid:18584554
Vaara M et al. Novel polymyxin derivatives carrying only three positive charges are effective antibacterial agents. 2008 Antimicrob. Agents Chemother. pmid:18591267
Amsler KM et al. In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. 2008 Antimicrob. Agents Chemother. pmid:18591277
DiPersio LP et al. Prevalence of the erm(T) gene in clinical isolates of erythromycin-resistant group D Streptococcus and Enterococcus. 2008 Antimicrob. Agents Chemother. pmid:18285483
Khalil H et al. Synergy between polyethylenimine and different families of antibiotics against a resistant clinical isolate of Pseudomonas aeruginosa. 2008 Antimicrob. Agents Chemother. pmid:18285485
Cochetti I et al. erm(B)-carrying elements in tetracycline-resistant pneumococci and correspondence between Tn1545 and Tn6003. 2008 Antimicrob. Agents Chemother. pmid:18285489
Cassiday PK et al. Co-infection with two different strains of Bordetella pertussis in an infant. 2008 J. Med. Microbiol. pmid:18287306
Yang Y [Mechanism and clinical application of erythromycin as a gastrointestinal prokinetic agent in children]. 2008 Zhongguo Dang Dai Er Ke Za Zhi pmid:18289489
Inoue D et al. Erythromycin attenuates MUC5AC synthesis and secretion in cultured human tracheal cells infected with RV14. 2008 Respirology pmid:18339018
Ahlin G et al. Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. 2008 J. Med. Chem. pmid:18788725
Hayashi S et al. Characterization of multinuclear hepatocytes induced in rats by mitemcinal (GM-611), an erythromycin derivative. 2008 Toxicol Pathol pmid:18776165
Liu ZQ et al. Efflux pump gene hefA of Helicobacter pylori plays an important role in multidrug resistance. 2008 World J. Gastroenterol. pmid:18777600
Venkatasubramani N et al. Erythromycin lacks colon prokinetic effect in children with functional gastrointestinal disorders: a retrospective study. 2008 BMC Gastroenterol pmid:18718006
Komuro I et al. Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBPbeta. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:18719105
Yang F et al. Antimicrobial susceptibility and molecular epidemiology of Streptococcus pneumoniae isolated from Shanghai, China. 2008 Int. J. Antimicrob. Agents pmid:18723327
Seemungal TA et al. Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations. 2008 Am. J. Respir. Crit. Care Med. pmid:18723437
Mally M and Cornelis GR Genetic tools for studying Capnocytophaga canimorsus. 2008 Appl. Environ. Microbiol. pmid:18723653
Dorfman MS et al. The pharmacodynamic properties of azithromycin in a kinetics-of-kill model and implications for bacterial conjunctivitis treatment. 2008 Adv Ther pmid:18369536
Mendes RE et al. First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States. 2008 Antimicrob. Agents Chemother. pmid:18391032
Karabiber N and Mert Dinc B Erythromycin-heteroresistant methicillin-resistant Staphylococcus aureus isolates from Turkey. 2008 Clin. Microbiol. Infect. pmid:18397328
Korolkiewicz RP and Kuziemski K Use of erythromycin in prevention or treatment of postoperative ileus. 2008 Urology pmid:18400282
Luppens SB et al. Effect of Veillonella parvula on the antimicrobial resistance and gene expression of Streptococcus mutans grown in a dual-species biofilm. 2008 Oral Microbiol. Immunol. pmid:18402603
Min YH et al. Molecular analysis of constitutive mutations in ermB and ermA selected in vitro from inducibly MLSB-resistant enterococci. 2008 Arch. Pharm. Res. pmid:18409053
Besier S et al. The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates. 2008 Antimicrob. Agents Chemother. pmid:18378706
Reinert RR et al. Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. 2008 Antimicrob. Agents Chemother. pmid:18378707
Kumari N et al. Detection of pbp2b and ermB genes in clinical isolates of Streptococcus pneumoniae. 2008 J Infect Dev Ctries pmid:19738350
Bendahou A et al. Characterization of Staphylococcus species isolated from raw milk and milk products (lben and jben) in North Morocco. 2008 J Infect Dev Ctries pmid:19738354
Betancor L et al. Improved catalytic activity of a purified multienzyme from a modular polyketide synthase after coexpression with Streptomyces chaperonins in Escherichia coli. 2008 Chembiochem pmid:19021139
Olsson C et al. Identification of genes for the ghrelin and motilin receptors and a novel related gene in fish, and stimulation of intestinal motility in zebrafish (Danio rerio) by ghrelin and motilin. 2008 Gen. Comp. Endocrinol. pmid:17582410
Rhodes LD et al. Characterization of Renibacterium salmoninarum with reduced susceptibility to macrolide antibiotics by a standardized antibiotic susceptibility test. 2008 Dis. Aquat. Org. pmid:18814542
Moore SD and Sauer RT Revisiting the mechanism of macrolide-antibiotic resistance mediated by ribosomal protein L22. 2008 Proc. Natl. Acad. Sci. U.S.A. pmid:19015512
Yao SM et al. Antimicrobial susceptibility testing of Bordetella pertussis in Taiwan prompted by a case of pertussis in a paediatric patient. 2008 J. Med. Microbiol. pmid:19018032
Westaway SM et al. The discovery of biaryl carboxamides as novel small molecule agonists of the motilin receptor. 2008 Bioorg. Med. Chem. Lett. pmid:19006669
Priscila G et al. Expression of the bacterial hemoglobin gene from Vitreoscilla stercoraria increases rifamycin B production in Amycolatopsis mediterranei. 2008 J. Biosci. Bioeng. pmid:19111646
Limouris GS et al. Selective hepatic arterial infusion of In-111-DTPA-Phe1-octreotide in neuroendocrine liver metastases. 2008 Eur. J. Nucl. Med. Mol. Imaging pmid:18536916
Crasta OR et al. Genome sequence of Brucella abortus vaccine strain S19 compared to virulent strains yields candidate virulence genes. 2008 PLoS ONE pmid:18478107
Pinto A et al. Synthesis and pharmacological characterization at glutamate receptors of the four enantiopure isomers of tricholomic acid. 2008 J. Med. Chem. pmid:18338843
Gan M et al. Glycosides from the root of Iodes cirrhosa. 2008 J. Nat. Prod. pmid:18327912
Bartels AL et al. Decreased blood-brain barrier P-glycoprotein function in the progression of Parkinson's disease, PSP and MSA. 2008 J Neural Transm (Vienna) pmid:18265929
Zhang M et al. Recombinant anti-vascular endothelial growth factor fusion protein efficiently suppresses choridal neovasularization in monkeys. 2008 Mol. Vis. pmid:18246030
Li X et al. Fluorinated porphyrin tweezer: a powerful reporter of absolute configuration for erythro and threo diols, amino alcohols, and diamines. 2008 J. Am. Chem. Soc. pmid:18211067