erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Airway Obstruction D000402 13 associated lipids
Tuberculosis D014376 20 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nocardia Infections D009617 6 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Hearing Loss, Sensorineural D006319 8 associated lipids
Otitis Media D010033 12 associated lipids
Adenocarcinoma D000230 166 associated lipids
Bacterial Infections D001424 21 associated lipids
Otitis Externa D010032 8 associated lipids
Pain D010146 64 associated lipids
Autoimmune Diseases D001327 27 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Stomach Diseases D013272 7 associated lipids
Genital Diseases, Female D005831 7 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pulmonary Fibrosis D011658 24 associated lipids
Skin Neoplasms D012878 12 associated lipids
Pleurisy D010998 20 associated lipids
Inflammation D007249 119 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Genital Diseases, Male D005832 3 associated lipids
Sexually Transmitted Diseases D012749 4 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Bone Resorption D001862 7 associated lipids
Arthritis D001168 41 associated lipids
Surgical Wound Infection D013530 7 associated lipids
Abscess D000038 13 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Heart Failure D006333 36 associated lipids
Osteitis D010000 10 associated lipids
Osteomyelitis D010019 10 associated lipids
Liver Diseases D008107 31 associated lipids
Corneal Diseases D003316 13 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Pancreatitis D010195 10 associated lipids
Hypersensitivity D006967 22 associated lipids
Acne Vulgaris D000152 35 associated lipids
Osteolysis D010014 8 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Pawlowski AC et al. The evolution of substrate discrimination in macrolide antibiotic resistance enzymes. 2018 Nat Commun pmid:29317655
Ababou A New insights into the structural and functional involvement of the gate loop in AcrB export activity. 2018 Biochim. Biophys. Acta pmid:29126836
Li A et al. Development of Guanfacine Extended-Release Dosing Strategies in Children and Adolescents with ADHD Using a Physiologically Based Pharmacokinetic Model to Predict Drug-Drug Interactions with Moderate CYP3A4 Inhibitors or Inducers. 2018 Paediatr Drugs pmid:29098603
Tapia C et al. 2018 Rev Chilena Infectol pmid:29912257
Jaén-Gil A et al. An automated on-line turbulent flow liquid-chromatography technology coupled to a high resolution mass spectrometer LTQ-Orbitrap for suspect screening of antibiotic transformation products during microalgae wastewater treatment. 2018 J Chromatogr A pmid:29910089
Kulesa A et al. Combinatorial drug discovery in nanoliter droplets. 2018 Proc. Natl. Acad. Sci. U.S.A. pmid:29899149
Ersoy B et al. The anti-inflammatory effects of erythromycin, clarithromycin, azithromycin and roxithromycin on histamine-induced otitis media with effusion in guinea pigs. 2018 J Laryngol Otol pmid:29888693
Nishina T et al. [A case of relapsed neurosyphilis with progressive left hemiparesis]. 2018 Rinsho Shinkeigaku pmid:29863099
Zhang Z et al. The pathogenic and antimicrobial characteristics of an emerging Streptococcus agalactiae serotype IX in Tilapia. 2018 Microb. Pathog. pmid:29859291
Chuo SC et al. Reverse micelle Extraction of Antibiotics using an Eco-friendly Sophorolipids Biosurfactant. 2018 Sci Rep pmid:29323139
Teixeira DDS et al. Topical chlorhexidine, povidone-iodine and erythromycin in the repair of traumatic ulcers on the rat tongue: Clinical, histological and microbiological evaluation. 2018 Arch. Oral Biol. pmid:29316457
Patil BN and Taranath TC Limonia acidissima L. leaf mediated synthesis of silver and zinc oxide nanoparticles and their antibacterial activities. 2018 Microb. Pathog. pmid:29248515
Ramos CJ et al. The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability. 2018 J. Biol. Chem. pmid:29158262
Dias-Souza MV et al. Euterpe oleracea pulp extract: Chemical analyses, antibiofilm activity against Staphylococcus aureus, cytotoxicity and interference on the activity of antimicrobial drugs. 2018 Microb. Pathog. pmid:29146496
Cao Q et al. Haemophilus parasuis CpxRA two-component system confers bacterial tolerance to environmental stresses and macrolide resistance. 2018 Microbiol. Res. pmid:29146255
Schafhauser BH et al. Global review and analysis of erythromycin in the environment: Occurrence, bioaccumulation and antibiotic resistance hazards. 2018 Environ. Pollut. pmid:29587215
Kleinert C et al. T lymphocyte-proliferative responses of harbor seal (Phoca vitulina) peripheral blood mononuclear cells (PBMCs) exposed to pharmaceuticals in vitro. 2018 Mar. Pollut. Bull. pmid:29475659
Chen CJ et al. Clinical and molecular features of MDR livestock-associated MRSA ST9 with staphylococcal cassette chromosome mecXII in humans. 2018 J. Antimicrob. Chemother. pmid:29048488
Pérez RA et al. Analysis of macrolide antibiotics in water by magnetic solid-phase extraction and liquid chromatography-tandem mass spectrometry. 2017 J Pharm Biomed Anal pmid:28858671
Zankari E et al. PointFinder: a novel web tool for WGS-based detection of antimicrobial resistance associated with chromosomal point mutations in bacterial pathogens. 2017 J. Antimicrob. Chemother. pmid:29091202
Giguère S et al. Antimicrobial Resistance in . 2017 Microbiol Spectr pmid:29052538
Liu J et al. Interaction of erythromycin and ketoconazole on the neurological, biochemical and behavioral responses in crucian carp. 2017 Environ. Toxicol. Pharmacol. pmid:28802958
Štšepetova J et al. Assessment of phenotypic and genotypic antibiotic susceptibility of vaginal Lactobacillus sp. 2017 J. Appl. Microbiol. pmid:28574626
Tanaka Y et al. Applicability of ribosome engineering to vitamin B12 production by Propionibacterium shermanii. 2017 Biosci. Biotechnol. Biochem. pmid:28532245
Demczuk WHB et al. Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. 2017 PLoS ONE pmid:28531208
Cheled-Shoval S et al. From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. 2017 Molecules pmid:28513558
Sato T et al. Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. 2017 Microbiol. Immunol. pmid:28504455
Wozniak A et al. Importance of adhesins in the recurrence of pharyngeal infections caused by Streptococcus pyogenes. 2017 J. Med. Microbiol. pmid:28463664
Pavlova A et al. Toward the rational design of macrolide antibiotics to combat resistance. 2017 Chem Biol Drug Des pmid:28419786
Sugimoto N et al. Invasive pneumococcal disease caused by mucoid serotype 3 Streptococcus pneumoniae: a case report and literature review. 2017 BMC Res Notes pmid:28057059
Liu J et al. Modulation of erythromycin-induced biochemical responses in crucian carp by ketoconazole. 2017 Environ Sci Pollut Res Int pmid:28004371
Hillitt KL et al. Antimicrobial activity of Manuka honey against antibiotic-resistant strains of the cell wall-free bacteria Ureaplasma parvum and Ureaplasma urealyticum. 2017 Lett. Appl. Microbiol. pmid:27992658
Numanović F et al. Presence and resistance of Streptococcus agalactiae in vaginal specimens of pregnant and adult non-pregnant women and association with other aerobic bacteria. 2017 Med Glas (Zenica) pmid:27917849
Parthasarathy G et al. Relationship Between Gastric Emptying and Diurnal Glycemic Control in Type 1 Diabetes Mellitus: A Randomized Trial. 2017 J. Clin. Endocrinol. Metab. pmid:27880079
Pavlović D et al. Synthesis of novel 15-membered 8a-azahomoerythromycin A acylides: Consequences of structural modification at the C-3 and C-6 position on antibacterial activity. 2017 Eur J Med Chem pmid:27657812
Lim SK et al. Macrolide resistance mechanisms and virulence factors in erythromycin-resistant Campylobacter species isolated from chicken and swine feces and carcasses. 2017 J. Vet. Med. Sci. pmid:27593510
Ricker EB and Nuxoll E Synergistic effects of heat and antibiotics on Pseudomonas aeruginosa biofilms. 2017 Biofouling pmid:29039211
Bitew A et al. Species distribution and antibiotic susceptibility profile of bacterial uropathogens among patients complaining urinary tract infections. 2017 BMC Infect. Dis. pmid:28962545
Öksüz L and Gürler N [Serotype distribution and antibiotic resistance of Streptococcus pneumoniae strains isolated from the adult patients in a Turkish üniversity hospital]. 2017 Mikrobiyol Bul pmid:28929957
Pan M and Chu LM Transfer of antibiotics from wastewater or animal manure to soil and edible crops. 2017 Environ. Pollut. pmid:28866424
Wekselman I et al. The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel. 2017 Structure pmid:28689968
Truong-Bolduc QC et al. Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump. 2017 Antimicrob. Agents Chemother. pmid:28584148
Blackwell GA and Hall RM The Determinant and the Genes in Acinetobacter Plasmids Are Each Part of Discrete Modules Flanked by Inversely Oriented p (XerC-XerD) Sites. 2017 Antimicrob. Agents Chemother. pmid:28533235
Duelge KJ et al. An LC-MS/MS method for the determination of antibiotic residues in distillers grains. 2017 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:28415016
Atkinson CT et al. Expression of acquired macrolide resistance genes in Haemophilus influenzae. 2017 J. Antimicrob. Chemother. pmid:28961896
Zhou Z et al. Combination of Erythromycin and Curcumin Alleviates Induced Osteomyelitis in Rats. 2017 Front Cell Infect Microbiol pmid:28884090
Peng Z et al. Genomic insights into the pathogenicity and environmental adaptability of Enterococcus hirae R17 isolated from pork offered for retail sale. 2017 Microbiologyopen pmid:28799224
Quinn KL et al. Macrolides, Digoxin Toxicity and the Risk of Sudden Death: A Population-Based Study. 2017 Drug Saf pmid:28421551
Zhao L et al. Occurrence of erythromycin and its degradation products residues in honey. Validation of an analytical method. 2017 J Sep Sci pmid:28121061
Dreno B et al. Skin microbiome and acne vulgaris: Staphylococcus, a new actor in acne. 2017 Exp. Dermatol. pmid:28094874