erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ivashkin VT et al. | [The epidemiological, clinical, diagnostic and treatment aspects of Legionella infection]. | 1992 | Voen Med Zh | pmid:1448947 |
Hsieh PF et al. | The Klebsiella pneumoniae YfgL (BamB) lipoprotein contributes to outer membrane protein biogenesis, type-1 fimbriae expression, anti-phagocytosis, and in vivo virulence. | 2016 | Virulence | pmid:27029012 |
Novick R | Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. | 1967 | Virology | pmid:4227577 |
Owens RA and Bruening G | The pattern of amino acid incorporation into two cowpea mosaic virus proteins in the presence of ribosome-specific protein synthesis inhibitors. | 1975 | Virology | pmid:124497 |
Inoue M et al. | Integration of the erythromycin (ero) resistance gene of a staphylococcal plasmid into S1ppen.ion phage. | 1976 | Virology | pmid:134503 |
Kreft A et al. | JAK2-V617F-mutated myeloproliferative neoplasms reveal different allele burden within hematopoietic cell lineages: a microdissection study of bone marrow trephine biopsies. | 2011 | Virchows Arch. | pmid:22006129 |
DUGAS M | [Erythromycin]. | 1954 | Vie Med | pmid:13179453 |
MASPETIOL R et al. | [The propionic ester of erythromycin in ORL]. | 1961 | Vie Med | pmid:14470873 |
Kovaleva NP | [Susceptibility to antibiotics of Staphylococcus and Bact. coli]. | 1973 | Veterinariia | pmid:4618399 |
Saryev GA et al. | [Erythromycin in abortion of the sheep caused by Chlamydia]. | 1977 | Veterinariia | pmid:595362 |
SimetskiÄ OA | [Erythromycin in the treatment of cows with subclinical mastitis]. | 1965 | Veterinariia | pmid:5895871 |
Parikov VA et al. | [Effectiveness of antimastitis preparations]. | 1976 | Veterinariia | pmid:1014354 |
Bajwa NS et al. | Pharmacokinetic profile of erythromycin after intramammary administration in lactating dairy cows with specific mastitis. | 2007 | Vet. Res. Commun. | pmid:17225083 |
Villar D et al. | Novobiocin inhibits both UDP-glucuronosyltransferase and cytochrome P450-mediated enzyme activities in pig liver microsomes. | 1998 | Vet. Res. Commun. | pmid:9810637 |
Carletti M et al. | In vitro formation of metabolic-intermediate cytochrome P450 complexes in rabbit liver microsomes by tiamulin and various macrolides. | 2003 Jul-Aug | Vet. Res. | pmid:12911857 |
Jackson G and Boughton E | A mild outbreak of bovine mastitis associated with Mycoplasma bovigenitalium. | 1991 | Vet. Rec. | pmid:1781137 |
Edmondson PW | An economic justification of "blitz" therapy to eradicate Streptococcus agalactiae from a dairy herd. | 1989 | Vet. Rec. | pmid:2514481 |
Laven RA and Hunt H | Evaluation of copper sulphate, formalin and peracetic acid in footbaths for the treatment of digital dermatitis in cattle. | 2002 | Vet. Rec. | pmid:12199433 |
Boyer PJ | Outbreak of clinical mastitis in dairy cows following 'blitz' therapy. | 1997 | Vet. Rec. | pmid:9253837 |
Lacey RW | Rarity of tylosin resistance in human pathogenic bacteria. | 1988 | Vet. Rec. | pmid:3293307 |