erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Stang EM and White MC | On the macrocyclization of the erythromycin core: preorganization is not required. | 2011 | Angew. Chem. Int. Ed. Engl. | pmid:21344559 |
Qin SS et al. | Antimicrobial resistance in Campylobacter coli isolated from pigs in two provinces of China. | 2011 | Int. J. Food Microbiol. | pmid:21349598 |
Nguyen NQ et al. | Plasma erythromycin concentrations predict feeding outcomes in critically ill patients with feed intolerance. | 2011 | Crit. Care Med. | pmid:21297459 |
Thenmozhi R et al. | Characterization of biofilms in different clinical M serotypes of Streptococcus pyogenes. | 2011 | J. Basic Microbiol. | pmid:21298675 |
Tosin M et al. | In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines. | 2011 | Chem. Commun. (Camb.) | pmid:21301753 |
Mingoia M et al. | Heterogeneity of Tn5253-like composite elements in clinical Streptococcus pneumoniae isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:21263055 |
Lubell Y et al. | Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. | 2011 | Trop. Med. Int. Health | pmid:21740488 |
Spigaglia P et al. | Multidrug resistance in European Clostridium difficile clinical isolates. | 2011 | J. Antimicrob. Chemother. | pmid:21771851 |
Jupelli M et al. | Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life. | 2011 | Lab. Invest. | pmid:21769086 |
Clifford V et al. | Variation in erythromycin and clindamycin resistance patterns between New Zealand and Australian group B streptococcus isolates. | 2011 | Aust N Z J Obstet Gynaecol | pmid:21806568 |
Nielsen EI et al. | Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization. | 2011 | Antimicrob. Agents Chemother. | pmid:21807983 |
Liu Y et al. | The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21570844 |
Samra Z et al. | Susceptibility of Ureaplasma urealyticum to tetracycline, doxycycline, erythromycin, roxithromycin, clarithromycin, azithromycin, levofloxacin and moxifloxacin. | 2011 | J Chemother | pmid:21571622 |
Bistrian BR | Enteral feeding: good, but not for everyone. | 2011 | Crit. Care Med. | pmid:21613857 |
Öberg AI et al. | β-Adrenergic inhibition of contractility in L6 skeletal muscle cells. | 2011 | PLoS ONE | pmid:21829455 |
Osman M and Ghosh SK | Semiparametric bayesian testing procedure for noninferiority trials with binary endpoints. | 2011 | J Biopharm Stat | pmid:21830923 |
Baronsky J et al. | Perfusion calorimetry in the characterization of solvates forming isomorphic desolvates. | 2011 | Eur J Pharm Sci | pmid:21726637 |
Dixon-Woods M et al. | Providing the results of research to participants: a mixed-method study of the benefits and challenges of a consultative approach. | 2011 | Clin Trials | pmid:21730081 |
Pannu J et al. | In vitro antibacterial activity of NB-003 against Propionibacterium acnes. | 2011 | Antimicrob. Agents Chemother. | pmid:21746943 |
Daram SR and Garretson R | Erythromycin is preferable to metoclopramide as a prokinetic in acute upper GI bleeding. | 2011 | Gastrointest. Endosc. | pmid:21704823 |
Albarellos GA et al. | Pharmacokinetics of erythromycin after intravenous, intramuscular and oral administration to cats. | 2011 | Vet. J. | pmid:19854664 |
Motoyama M et al. | Residues of pharmaceutical products in recycled organic manure produced from sewage sludge and solid waste from livestock and relationship to their fermentation level. | 2011 | Chemosphere | pmid:21570103 |
Bonofiglio L et al. | Dissemination of an erythromycin-resistant penicillin-nonsusceptible Streptococcus pneumoniae Poland(6B)-20 clone in Argentina. | 2011 | Microb. Drug Resist. | pmid:21128835 |
Zanoni RG et al. | Occurrence of Helicobacter pullorum in turkeys. | 2011 | Vet. Microbiol. | pmid:21144678 |
Altraif I et al. | Effect of erythromycin before endoscopy in patients presenting with variceal bleeding: a prospective, randomized, double-blind, placebo-controlled trial. | 2011 | Gastrointest. Endosc. | pmid:21145052 |
Bopp LH et al. | Activities of tigecycline and comparators against Legionella pneumophila and Legionella micdadei extracellularly and in human monocyte-derived macrophages. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21146719 |
Braga TM et al. | Involvement, and dissemination, of the enterococcal small multidrug resistance transporter QacZ in resistance to quaternary ammonium compounds. | 2011 | J. Antimicrob. Chemother. | pmid:21147826 |
Allen VG et al. | Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. | 2011 | Antimicrob. Agents Chemother. | pmid:21098249 |
Feneran AN et al. | Retinoid plus antimicrobial combination treatments for acne. | 2011 | Clin Cosmet Investig Dermatol | pmid:21760743 |
Mueller DH et al. | Constraints to implementing the Essential Health Package in Malawi. | 2011 | PLoS ONE | pmid:21695115 |
Pérez-Trallero E et al. | In vitro activities of retapamulin and 16 other antimicrobial agents against recently obtained Streptococcus pyogenes isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:21343452 |
Filić D et al. | Crystal structure and physicochemical properties of crystalline form of 2'-O-{3-[(7-chloro-4-quinolinyl)amino]propyl}-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A. | 2011 | J Pharm Sci | pmid:21394721 |
van den Bosch S et al. | Erythromycin to promote bedside placement of a self-propelled nasojejunal feeding tube in non-critically ill patients having pancreatitis: a randomized, double-blind, placebo-controlled study. | 2011 | Nutr Clin Pract | pmid:21447772 |
Louvet JN et al. | Simultaneous Gram and viability staining on activated sludge exposed to erythromycin: 3D CLSM time-lapse imaging of bacterial disintegration. | 2011 | Int J Hyg Environ Health | pmid:21420358 |
Serdoz F et al. | Development and pharmacokinetic evaluation of erythromycin lipidic formulations for oral administration in rainbow trout (Oncorhynchus mykiss). | 2011 | Eur J Pharm Biopharm | pmid:21402156 |
Dow GS et al. | Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice. | 2011 | Malar. J. | pmid:21645370 |
Piccialli V et al. | Isolation of a bis-iodurated tetra-THF as a trace product from the oxidation of squalene with RuOâ‚„ and its double ring expansion to a novel bis-THF-bis-THP compound. | 2011 | Molecules | pmid:21709619 |
Justa RF et al. | Bacillary angiomatosis in HIV-positive patient from Northeastern Brazil: a case report. | 2011 | Rev. Soc. Bras. Med. Trop. | pmid:22031085 |
Jakeman DL and Sadeghi-Khomami A | A β-(1,2)-glycosynthase and an attempted selection method for the directed evolution of glycosynthases. | 2011 | Biochemistry | pmid:22035228 |
Zhou Y et al. | [Detection and the antibiotic susceptibility analysis of mycoplasma and chlamydia in urogenital tract infections of 327 cases patients with tubal infertility]. | 2011 | Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi | pmid:21977592 |
Farkas B et al. | [Frequency and antibiotic resistance of Ureaplasma urealyticum and Mycoplasma hominis in genital samples of sexually active individuals]. | 2011 | Orv Hetil | pmid:21979223 |
Gray KL et al. | The outpatient institutional antibiogram does not accurately reflect the susceptibility of prepartum group B streptococcal isolates to erythromycin and clindamycin. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:21982562 |
Sugawara A et al. | Novel 12-membered non-antibiotic macrolides from erythromycin A; EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents. | 2011 | Bioorg. Med. Chem. Lett. | pmid:21524580 |
Cong C et al. | Synthesis and antibacterial activity of novel 4″-O-benzimidazolyl clarithromycin derivatives. | 2011 | Eur J Med Chem | pmid:21524827 |
Ando F et al. | Synergic effects of β-estradiol and erythromycin on hERG currents. | 2011 | J. Membr. Biol. | pmid:21484263 |
Flaman AS et al. | The effect of interferon-α on the expression of cytochrome P450 3A4 in human hepatoma cells. | 2011 | Toxicol. Appl. Pharmacol. | pmid:21466820 |
Zou LK et al. | Erythromycin resistance and virulence genes in Enterococcus faecalis from swine in China. | 2011 | New Microbiol. | pmid:21344149 |
Liu L et al. | Disappearance of sexual dimorphism in triptolide metabolism in monosodium glutamate treated neonatal rats. | 2011 | Arzneimittelforschung | pmid:21428244 |
Lee Y et al. | Chemistry and biology of macrolide antiparasitic agents. | 2011 | J. Med. Chem. | pmid:21428405 |
Bansal BK et al. | Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health. | 2011 | Trop Anim Health Prod | pmid:20844949 |